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National Comprehensive Cancer Network


Well-timed nudges help care providers to honor the wishes of patients with cancer according to JNCCN study

Researchers developed a two-pronged approach to encourage important conversations between patients with cancer and their oncologists about goals and preferences for care. The study found that combining reminders for both patients and providers at the right moment significantly increased serious illness conversations.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·TypeRandomized controlled/clinical trial·DateJun 15, 2026

New awards and publications showcase achievements from staff at the National Comprehensive Cancer Network

NCCN staff received awards and publications for advancing quality cancer care, including Dr. Alyssa Schatz's Leadership in Policy, Equity, and Advocacy award and Faviolla Baez-Cruz's publication on biochemical research. The National Comprehensive Cancer Network is recognized for its work to improve outcomes for people with cancer.

NCCN 2026 Annual Conference prepares cancer care providers worldwide for healing the whole patient

The NCCN 2026 Annual Conference emphasized the need for holistic care for adolescents and young adults with cancer, highlighting unique challenges and the importance of supportive services. The conference also addressed global cancer care realities and future strategies, emphasizing the need for collaboration and investment to address ...

Human approach is hypothesized to be superior to technology for supportive cancer care according to new data in JNCCN

A recent study found that team-based clinic participants perceived significant improvements in patient care, whereas technology-based clinic participants saw limited benefits. The study highlights the importance of human interaction and values-centered care in supportive cancer care.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateNov 10, 2025

New JNCCN study confirms it’s ‘never too late’ to see survival benefits from quitting smoking—even with late-stage cancer

Researchers found that patients with stage III or IV cancer who quit smoking lived significantly longer than those who continued smoking, with a two-fold lower rate of all-cause mortality. The study's findings emphasize the crucial role of smoking cessation support as part of standard cancer care.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateOct 9, 2025

New research in JNCCN offers a simplified way to identify harmful medications in older adults with cancer

Researchers evaluated a tool based on NCCN Guidelines to identify high-risk medications and their association with frailty and outcomes in over 380,000 older adults diagnosed with cancer. The study found that each additional high-risk medication increased the odds of being mildly or moderately-to-severely frail by 66%.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateSep 10, 2025

New research in JNCCN offers reassurance about localized prostate cancer prognosis

A study of 62,839 people diagnosed with non-metastatic prostate cancer in Sweden found that those treated according to NCCN Guidelines were likely to survive their cancer for their remaining life-expectancy. Those with low- and intermediate-risk cancer were six times more likely to die of other causes than prostate cancer.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateJul 10, 2025

New research in JNCCN finds stark disparities in treatment and survival time for people with pancreatic cancer

Researchers found significant disparities in quality of care and outcomes for patients with metastatic pancreatic cancer. Patients with higher social vulnerability indices were less likely to receive guideline-concordant systemic therapy, palliative care, or survive over 12 months.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateApr 9, 2025

Patient advocates from NCCN guidelines panels share their ‘united by unique’ stories for world cancer day

The National Comprehensive Cancer Network is joining the global effort to improve awareness and knowledge of cancer risks through its 'United by Unique' campaign. Patient advocates from NCCN guidelines panels are sharing their personal stories to highlight the importance of a people-centered approach in cancer care, which recognizes ev...

NCCN joins international meeting to improve cancer care in the Middle East and North Africa region

The National Comprehensive Cancer Network (NCCN) has joined a two-day meeting in Riyadh, Saudi Arabia, to review updated NCCN Clinical Practice Guidelines for the MENA region. The guidelines provide evidence-based expert consensus-driven recommendations for cancer prevention, screening, treatment, and supportive care, tailored for uniq...

New evidence-based information from NCCN offers tangible and moral support for people trying to quit smoking

The new NCCN Guidelines for Patients: Quitting Smoking provide critical support and guidance for individuals with cancer seeking to quit smoking. The guidelines offer a fresh perspective and renewed hope, featuring multiple evidence-based options, including nicotine replacement therapy, behavior therapy, and non-nicotine medicines.

Cancer genetic risk assessment guidelines expand to meet growing understanding of hereditary risk

The National Comprehensive Cancer Network has updated its guidelines for genetic/familial high-risk assessment, incorporating the latest scientific research and expert recommendations to enhance screening practices and treatment options. The expanded guidelines cover various cancer types and provide guidance on genetic testing, heredit...

National Comprehensive Cancer Network joins with Vietnam National Cancer Hospital to enhance cancer treatment

The National Comprehensive Cancer Network has joined forces with the Vietnam National Cancer Hospital to create Harmonized Guidelines for Vietnam, a framework for improving and standardizing cancer care in the country. The guidelines are based on NCCN's Clinical Practice Guidelines in Oncology, with modifications to reflect local needs.

New JNCCN study suggests Medicaid expansion improves cancer care and survival for people with aggressive type of breast cancer

A new study published in JNCCN found that Medicaid expansion was associated with longer survival rates and reduced treatment delays for patients with HR-negative, HER2-positive breast cancer. The study used data from the National Cancer Database to review results for women diagnosed with this type of breast cancer between 2010 and 2018.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateOct 24, 2024

New study in JNCCN supports chemotherapy option that reduces side effects for people with gastrointestinal cancers

Researchers found that omitting the bolus-specific 5-fluorouracil (5-FU) portion from common chemotherapy regimens improves tolerability without sacrificing treatment effectiveness. The study of 11,765 patients shows no decrease in overall survival but a notable reduction in cytopenias.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateSep 5, 2024

Pilot study in JNCCN explores new approach for reducing anxiety and improving quality of life after stem cell transplantation

Researchers developed a nine-week, phone-delivered positive psychology program called PATH to improve psychological well-being in blood cancer patients. The intervention had promising effects on patient-reported outcomes, with high participation and completion rates.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateJun 11, 2024

New findings in JNCCN illustrate pathway for screening high-risk individuals for pancreatic cancer in PRECEDE study

The PRECEDE study found that nearly 80% of participants in the highest-risk cohort completed baseline imaging, highlighting the feasibility of improving early detection and prevention for pancreatic cancer. Researchers recommend sorting individuals into three groups based on family history and genetic mutations to tailor surveillance.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateApr 16, 2024

Real world data shows impact of immunotherapy in populations underrepresented in clinical trials, according to JNCCN study

A recent study published in JNCCN found that patients from underrepresented groups treated with first-line immunotherapy for advanced Non-Small Cell Lung Cancer (NSCLC) showed similar survival outcomes as their White counterparts. The study analyzed data from 248 patients and highlighted the need for more diverse patient representation...

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateDec 11, 2023

New research in JNCCN suggests a simple and inexpensive option for reducing a major chemotherapy side-effect

New research suggests that vitamin D supplements can reduce the risk of peripheral neuropathy in patients undergoing paclitaxel treatment. The study found that patients with vitamin D deficiency were more likely to experience severe neuropathy, and that inducing vitamin D deficiency caused similar symptoms in a mice model study.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·DateNov 7, 2023

More Aggressive treatment doesn’t impact quality of life for metastatic colorectal cancer patients, according to new study in JNCCN

A new study published in JNCCN found that intensive local-regional treatment to remove as much tumor as possible did not significantly impact overall quality of life for patients with metastatic colorectal cancer. However, the treatment was associated with a higher risk of adverse events.

SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·TypeData/statistical analysis·DateOct 12, 2023