Dr. Kenneth M. Murphy is being recognized for his groundbreaking research on dendritic cell subsets, which regulate adaptive immune responses and have advanced the understanding of antigen presentation and immune system regulation. His work has informed strategies to enhance antitumor immunity and cancer immunotherapy.
A new SemCom framework prioritizes interpretability and compatibility with existing systems, enhancing transmission efficiency and robustness. The framework outperforms state-of-the-art methods in image transmission by over 20%, showcasing its potential for efficient semantic transmission in emerging 6G applications.
Researchers developed a graphite addition method to fabricate high-performance silicon carbide optical mirrors. The approach reduces free silicon content by 18.18% and enhances overall performance.
A new study by POSTECH researchers found that the protein tau interacts with DNA during cell division, forming condensates that capture microtubules. This interaction affects chromosome alignment and can lead to cellular abnormalities even in healthy cells.
This study reveals that HDAC3 epigenetically represses RASAL1, a key antifibrotic regulator, leading to enhanced fibroblast activation and extracellular matrix deposition in renal fibrosis. Restoring RASAL1 expression or inhibiting HDAC3 activity attenuates renal fibrosis.
Scientists developed a multifunctional molecule passivation strategy, achieving record-high EQE at 6,441 cd m^-2 and eliminating roll-off. The devices maintain 18.47% EQE at 9,587 cd m^-2 with nearly eliminated roll-off, showcasing improved optical performance.
A recent study published in Respiratory Physiology & Neurobiology found that breathing therapy devices don't affect all parts of the airway equally, with some areas experiencing stronger pressure and friction. The research provides valuable insights into how to improve device settings for patients with respiratory disorders.
A research team from the Chinese Academy of Sciences has developed a comprehensive model simulating the present-day dynamics of western North America's lithosphere and convecting mantle. The study reveals that magma beneath supervolcanoes originates in the shallow asthenosphere, challenging traditional hypotheses about magma generation.
A wireless ureteral stent sleeve, UroSleeve, tracks intrarenal pressure through resonance shifts, detecting pressure changes linked to hydronephrosis in an ex vivo porcine kidney model. The system could enable continuous remote follow-up and reduce dependence on episodic radiographic imaging.
Researchers from OIST used medieval records and buried trees to identify a sub-extreme solar proton event between winter 1200 CE and spring 1201 CE. They also reconstructed the Sun's activity cycle, which was shorter than today's eleven-year cycles.
A new study from UC Riverside shows that a locally adapted population of SoCal honeybees can naturally suppress deadly mites. The hybrid bees are less susceptible to Varroa mite infestations and cross-thresholds, making them more resistant than commercial breeds.
Researchers developed DARC-NESS, a model that explains why nightmares persist in children and how to break the cycle through tailored therapy. By focusing on nightmare efficacy and child response mechanisms, clinicians can create effective treatment plans to empower kids to master their dreams.
Scientists at University of Rochester identify a key mechanism behind methane production in the open ocean, which could worsen global warming. The research suggests that phosphate scarcity triggers methane-producing microbes to thrive, leading to more methane released into the atmosphere.
The Barrow Neuro Analytics Center has nearly doubled its dedicated research space to 18,000 square feet, supporting growing neurological research programs. Researchers at the center are globally renowned for their work on Parkinson's disease, Alzheimer's, and other neurological disorders using data-focused methods.
Two new TB vaccines, VPM1002 and Immuvac, demonstrate safety and effectiveness in preventing progression to active TB in latent infection, particularly in children. However, they do not offer general protection against all forms of TB or prevent weight-related mortality.
A study estimates that quitting tobacco could give a major economic uplift to over 20 million households in India, with the greatest impact felt in rural areas and among the poorest households. The analysis suggests that these households would receive a significant boost in income, potentially moving up one or two economic classes.
Natalie Bennett argues that the current food system is unsustainable, with half of global calories coming from just three crops. She proposes alternative approaches rooted in indigenous experience, such as permaculture and agroecological methods.
A new study by Bernard Capp reveals that refusing to doff one's hat was a potent act of political defiance during the civil war era, with elite men both adopting and resisting the practice. In contrast, an 18th-century Englishman's hat remained a powerful symbol of personal protection.
Researchers at Rice University have discovered a new way to enable pi interactions between dioxygen and f-block metals like neodymium, creating lanthanide-oxos. This breakthrough could lead to the development of highly reactive molecules as synthetic replacements for iron-oxo.
A real-world study found that adults taking GLP-1 RAs for weight loss have significantly lower total energy and protein intake. The use of an AI-powered nutritional tracking app revealed that 88% of users were under national protein guidelines, with many skipping meals to reduce protein intake.
A new study reveals that tropical trees have more positive interactions with their neighbors, leading to increased diversity and richness in these ecosystems. This finding may help explain why tropical forests are home to so many tree species.
A study by Cornell University researchers found that prompting employees to reflect on unintended outcomes leads to more creative ideas during brainstorming. Reflecting on past 'happy accidents' helps individuals regain control, leading to higher-quality ideas.
Researchers at São Paulo State University developed a theoretical framework for short Kitaev chains to serve as spectroscopic tools for identifying quantum statistics. The 'poor man's Majorana' configuration allows for the detection of quantum nature through spectral signatures.
A new system combines AI and EMS to physically guide users through unfamiliar tasks, marking a leap toward general-purpose, context-aware embodied assistance. Users are guided by dynamically generated muscle cues, adapting to mistakes and re-prompting the system for corrections.
Dr. Hongmei Wang joins Stem Cell Reports as an Associate Editor, bringing expertise in early embryo and placental development. Her laboratory investigates mechanisms governing embryonic and placental development, with potential for improving reproductive health outcomes.
A new longitudinal study from Université de Montréal finds that three simple movement habits in toddlerhood significantly predict a more physically active lifestyle in adolescence. Active play with parents, limited screen time, and sufficient sleep are key predictors of later physical activity levels.
Researchers at National Jewish Health used radiomics to analyze chest CT scans from 320 people with sarcoidosis, identifying four distinct imaging profiles linked to differences in lung function and disease severity. The approach could help advance diagnosis and patient care by providing objective measurements of lung abnormalities.
A national survey found significant disparities in IBS diagnosis across sex and racial groups in the US. Men and Black patients are less likely to receive a formal diagnosis compared to women and white patients, despite similar reported healthcare-seeking behavior and symptom severity.
A new study suggests that AI-written text messages can motivate older adults to move more, but cultural insensitivity and quality issues affect their responses. Participants rated only about 5% of the messages as culturally insensitive and roughly 6% had quality problems.
A new study by University of Maryland researcher Meredith Gore and colleagues found that traded wild mammals are 1.5 times more likely to share infectious agents with humans than species not involved in trade. The risk is higher for animals traded illegally or sold live, which fuels the demand for exotic pets.
A new $1.75 million grant from the Merck Foundation aims to address barriers to good heart health in Atlanta communities. The partnership delivers more personal support, pairing patients with community health workers who coordinate care and services.
MIT Sloan researchers demonstrate a new approach to designing social science experiments by applying integrative experiment design to a longstanding question about punishment in public goods games. The study reveals how punishment's effect on collective welfare can swing from substantially harmful to substantially helpful, depending on...
The Tennessee State University College of Agriculture and the University of Tennessee Institute of Agriculture have launched a joint seed funding program to support collaborative research projects focused on precision agriculture, biotechnology, and food security. The program aims to develop solutions that benefit producers, communitie...
A recent study found a significant link between very high PFAS exposure and an increased incidence of asthma in children. Researchers analyzed data from over 11,000 children born in Sweden and discovered that the risk of developing asthma was around 40% higher among those with very high PFAS exposure.
A retrospective cohort study found that outpatient early methadone dose titration is associated with improved treatment retention in individuals using fentanyl. This approach also lowers the risk of opioid toxicity, according to Canadian and US clinical guidance.
The discovery of an ancient egg containing the embryo of Lystrosaurus reveals that its ancestors laid eggs, and offers insights into their reproductive strategy. The large eggs suggest that Lystrosaurus did not produce milk for its young, and its precocial hatchlings were capable of feeding themselves.
Lauer and Barnes advocate for a national scientist databank, like the National Practitioner Data Bank, to promote transparency on staff misconduct. This approach could help institutions avoid problematic hires while allowing preventive steps to be taken by new employers.
A team of researchers discovered that the way cells sense oxygen determines if regeneration can even begin in mammalian limbs. They found that regenerative-competent amphibians show reduced oxygen-sensing capacity, while mammals respond strongly to oxygen and switch off regenerative programs.
Researchers found that Vibrio cholerae can efficiently acquire new sedentary chromosomal integron (SCI) gene cassettes from extracellular DNA. This process allows the bacteria to diversify its antiviral defenses and potentially expand its protection against viruses in different environments.
Researchers document a decades-long study of wild chimpanzee behavior, revealing a rare permanent split and subsequent lethal conflict within the Ngogo chimpanzee group. The study suggests that shifting social ties, competition over resources, and leadership changes can contribute to group divisions and violence.
A Swedish study found that high prenatal PFAS exposure is associated with a higher incidence of asthma in childhood. The research used a register-based cohort of children born between 2006 and 2013 to assess the relationship between maternal exposure and asthma outcomes.
A study led by Cleo Bertelsmeier found that wild mammals traded for pets, meat, or fur are 1.5 times more likely to share infectious agents with humans. The risk is higher when species are traded illegally or alive.
A recent study led by Cedars-Sinai Health Sciences University found that the same brain neurons are activated when people perceive and imagine objects. The research provides a detailed understanding of the neural mechanism underlying visual perception and creation of mental images in the human brain.
A new study links global wildlife trade to increased transmission of human-infecting pathogens, with traded mammals 40% more likely to harbor these diseases. The duration of species in trade amplifies this risk, suggesting cross-species transmission is inherent to the trade.
A large-scale experiment found that punishment consistently increases cooperation, but its effect on collective welfare varies depending on factors such as communication, contribution framing, and interaction duration. The study suggests that these elements interact in complex ways, with communication being the most influential factor.
A new analysis from UC San Francisco argues that diagnostics are being overlooked, slowing progress against major diseases despite advances in targeted therapies. The study suggests that nearly half of the world's population lacks adequate access to diagnostics due to inadequate investment and insurance reimbursement.
Researchers at the University of Texas at Austin observe permanent fission in wild chimpanzees, resulting in sustained intergroup violence. The findings suggest that relational dynamics can drive polarization and lethal conflict in chimps without language, ethnicity, or ideology.
A team led by Jiefu Li developed a new method to examine proteins lining the inside surface of blood vessels, revealing two proteins and pathways that play a role in opening and closing the blood-brain barrier. This discovery could help scientists understand how the barrier functions and develop better ways to deliver medicines for neu...
A new study by University Hospitals Harrington Heart & Vascular Institute highlights the long-term impact of preventive heart and vascular care. The study shows a significant decline in cardiovascular mortality rates after investments in local cardiac care, with notable reductions among older age groups.
A new multi-layer ionospheric mapping function for PPP-AR has been validated, improving convergence times by 4-10% and early-stage positioning. The method outperforms conventional Single Layer Model (SLM) in equatorial regions where ionospheric gradients are hardest to tame.
Researchers at UT MD Anderson have made significant advancements in cancer care, including a blood-based biomarker for cancer risk in people with Lynch Syndrome and a new target to sensitize pancreatic tumors to immunotherapy. The studies also identified a strategy to overcome radiation therapy resistance in lung cancer.
A mathematical model identifies universal patterns in competitive systems, revealing an optimal 'sweet spot' where excellence and opportunity coexist. The study found that high-performing systems strike a delicate balance between demand and opportunity.
Researchers have created a 3D experimental system to study the response of low-grade gliomas to drugs, providing a more realistic environment for testing treatments. The system uses organoids from pluripotent stem cells to replicate glioma development and characteristics.
Researchers developed an analytic tool using machine learning to predict how CPAP affects cardiovascular disease risk in patients with obstructive sleep apnea. The study found significant variation in treatment response across the cohort, identifying subgroups who benefited or were harmed by the therapy.
The conference discusses how funded literary translations represent cultural diversity and impact global circulation of texts, publishing market, and cultural policies. It is part of the research project Translating diversity: institutional agents and literary translation policies in Ibero-America.
A McGill-led study found that non-producing oil and gas wells emit microbial methane at rates roughly three times higher than earlier estimates. The team collected samples from 401 non-producing wells across Canada and detected traces of microbial methane in over 50% of them.
Researchers at UTIA are studying the genetic, cellular and microbial factors that influence feed efficiency in cattle. By identifying cell types, characterizing microbes and determining genetic influences, they aim to develop practical improvements for producers.
Researchers at BESSY II discovered a new method to investigate hydroxyl radicals, gaining surprising insights into their reaction pathway. They found that the proton of the hydroxyl radical reacts with TEMPO first, revealing an unexpected intermediate state.
A recent study published in Ecological Applications found that habitat restoration efforts in Forest Park have increased native bird diversity, with increases mostly seen in native species. The research also highlights the importance of access to water and varied habitats for boosting biodiversity.
Several open-source AI models consistently produced summaries that were more comprehensive than physician-written versions, particularly in capturing molecular and genetic findings. The study found that Llama 3.1 and DeepSeek performed best among the six evaluated models.
A new framework was developed to enable SMEs to systematically assess their supply chain risks and take proactive steps to build resilience. The integrated approach combines expert knowledge with established methods, identifying 11 key hazards across the supply chain.
Researchers found that orangutans and chimpanzees exhibit exactness in mimicking each other's facial expressions, particularly laugh faces, with a level of precision similar to humans. The study suggests that this ability may have given great apes important advantages in social interactions.
Researchers have developed an integrated reiterative pipeline that uses machine learning and structural biology to identify promising vaccine targets across multiple related viruses simultaneously. The system evaluates viral proteins to identify short fragments called epitopes that can trigger a strong immune response.
Researchers have developed a lead-free thin film that significantly improves the efficiency of microdevices in harvesting energy from ambient motion. The Mn-doped bismuth ferrite film exhibits stronger piezoelectric behavior, lower dielectric loss, and improved device-level performance.
A majority of Americans value U.S. membership in NATO and consider it a meaningful security asset, but views are sharply divided along partisan lines. Democrats are more supportive of NATO than Republicans, who hold less favorable views on the alliance's benefits to U.S. security.
A new study reveals that street greenery can reduce heat stress in cities, but its benefits depend on local conditions. The cooling effect is stronger in tropical and continental climates, but weaker in dry and temperate climates.
SKP2 functions as a signaling hub orchestrating metabolic reprogramming, DNA damage response, stem cell maintenance, and synaptic plasticity. Dysregulation contributes to human diseases, including cancer and neurodegenerative conditions.
A new study from Finland found that receiving an ADHD diagnosis earlier is associated with better academic performance and lower school dropout rates. Young people diagnosed earlier had a higher grade point average at age 16 and were more likely to pursue academic degrees.
Researchers at the University of Waterloo have discovered a safer and more effective way to treat Alzheimer's disease by combining anti-amyloid antibodies with molecules found in grapes, berries, peanuts, and turmeric. This combination approach neutralizes amyloid protein clumping in the brain, leading to better outcomes.
A recent study proposes an AI-enhanced evaluation framework to optimize city-scale municipal living plastic waste (MLPW) management. The framework addresses complex interplay of physical material flows, spatial infrastructure, and socio-economic factors, achieving a 96.3% reduction in annual greenhouse gas emissions by 2060.
UCLA investigators present new research on targeted drug delivery for colorectal cancer, COVID-19's impact on breast cancer outcomes, and AI in cancer diagnosis. These studies offer insights into overcoming drug resistance, enhancing immune responses, and improving outcomes for patients with difficult-to-treat cancers.
The INSPIRE Conference will discuss key project findings, tools, and resources on inclusive gender equality in research and innovation. The event aims to sustain change and address future challenges through dialogue among policymakers, researchers, and stakeholders.
Researchers focus on developing transformer efficiency and heat recovery to enhance hydrogen production energy efficiency. The goal is to significantly reduce electricity consumption by up to 35% and increase net efficiency to 85%.
Scientists develop a new generation of energy-efficient transistors made from thin, lightweight electrically conducting films. The film-based switch can control the flow of electric current with high precision, enabling complex motion sequences or fixed positions.
The study found that ATF5 plays a critical role in coordinating mitochondrial quality control and adaptive stress signaling in skeletal muscle. Absence of ATF5 resulted in increased muscle fatigability and elevated ROS production, highlighting its importance in maintaining muscle function with age.
Researchers have mapped the molecular mechanism behind allergic reactions and developed tailored antibodies to block life-threatening responses. The findings suggest a new approach to targeting the most important allergens and provide a starting point for developing more precise treatments for severe allergy.
A randomized, open-label bridging clinical trial was conducted to evaluate the immunogenicity and safety of a 9-valent HPV vaccine in adolescents aged 9-17 years compared to young women. The study found non-inferior immune responses with seroconversion rates comparable to those in young women receiving three doses.
Mount Sinai ophthalmologist has developed a groundbreaking device enabling precise measurement of aqueous outflow during eye surgery. The technology offers improved accuracy and reduced complications, potentially transforming the field of ophthalmology.
Researchers found that far-right influencer Tommy Robinson used his Telegram channel to comment on events and legitimise violence during anti-immigration protests in 2024, shaping followers' interpretations of events without issuing direct instructions. The study identifies key tactics used by influencers to create emotional conditions...
A new study by IIASA researchers reveals that China's economic growth is being driven by the skills of its workforce, not just its large working-age population. Improvements in skill composition have become a key driver of economic expansion, and a more favorable age structure enhances economic returns to workforce skills.
The clinical guideline emphasizes personalized care, recommending pre-exercise cardiovascular risk assessment and individualized exercise prescriptions. Adults with T2D are advised to engage in at least 150 minutes of moderate-intensity aerobic exercise per week, or a combination of aerobic and resistance training.
A proposed embedded ethics approach facilitates ethically responsible research with human stem-cell-based embryo models by integrating continuous dialogue among scientists, ethicists, and regulators. This framework helps build trust and serves as a public policy tool to ensure that research meets both scientific and societal values.
A team-based program in community health clinics helped low-income patients reduce their blood pressure more than standard care alone. After 18 months, patients in the team-based program saw a significant drop in systolic blood pressure and showed better adherence to hypertension treatment.
Researchers found that watching an online performance in real time boosts several aspects of the viewing experience, including a common factor of heightened sense of presence. The liveness effect weakens when viewers cannot see a performer's face, but going live can benefit streamers by motivating audience engagement.
The research team will analyze mouse models and human brain tissue to identify cell types that show early signs of stress before neurons die. The multiscale model simulates how the progressive loss or disconnection of specific neurons disrupts memory-related brain networks.
Adults aged 75 or older without adenoma on prior colonoscopy have lower risk of subsequent colorectal cancer and CRC death. Despite this, those with prior adenoma may consider deprioritizing surveillance colonoscopy relative to other health concerns.
A study found that children who need dental care the most are less likely to participate in school-based cavity prevention programs, which can lead to significant savings for state Medicaid programs. Improving participation among high-risk children could save up to $2.4 million annually.
A national study found that unmet health-related social needs are associated with lower colorectal cancer screening rates, particularly among adults aged 50-64. Addressing these needs may support age-specific strategies to improve screening rates.
Scientists used CAR-T cell therapy to treat a patient with severe autoimmune hemolytic anemia, immune thrombocytopenia, and antiphospholipid antibody syndrome. The treatment achieved lasting remission without additional treatment for over a year.
Researchers identify previously unknown microbe living in close partnership with another organism inside stromatolites, providing insights into how complex life began. The discovery sheds light on the evolution of eukaryotes and the emergence of mitochondria.
A new machine-learning method detects sudden changes in fluid behavior, improving simulation capabilities for everyday applications like weather prediction and nuclear reactor safety. This enables faster design testing, real-time adjustments, and reduced computational burden.
A new study uses an AI model to predict type 2 diabetes risk based on behavioral and psychosocial information. The digital twin model found that loneliness, insomnia, and poor mental health substantially raise a person's future risk of developing the disease.
A new study found that nearly half of young survivors of the October 7 attacks developed atypical sensory patterns, causing everyday stimuli to be perceived as overwhelming threats. This altered sensory processing is directly tied to emotional distress and anxiety in children.
Researchers compare viral and MASLD cirrhosis pathogenic mechanisms, identifying shared pathways and diagnostic differences. The study aims to establish a framework for prevention, diagnosis, treatment, and monitoring of MASLD cirrhosis.
During the Covid-19 crisis, small community sports clubs in Brazilian favelas adapted to meet urgent needs by distributing food parcels, sharing public health information, and transporting residents to vaccination centres. These efforts strengthened trust and cooperation with local communities.
KIT presents groundbreaking technologies for future energy supply, transportation and communication. The institution demonstrates visioner modes of travel, new options in robotics, decisive steps towards the first nuclear fusion reactor.
Researchers from Tohoku University examined the role of materials databases in supporting modern artificial intelligence tools used in materials science. They found that database architecture can directly affect AI model performance and reliability. The study aims to improve database quality, connectivity, and develop new AI systems th...
New research highlights a critical paradox in marine conservation: protected areas can become 'toxic traps' for pollutants. The authors propose an integrated management framework to address this issue. Effective conservation requires considering ecosystem health and pollutant exposure.
Researchers at DGIST have developed a novel catalytic technology that can easily assemble key structural frameworks of bioactive compounds exclusively in the desired mirror-image form. The technology uses an inexpensive nickel catalyst to synthesize β-methylene carbonyl derivatives, which are crucial for pharmaceuticals.
New research reveals that mosquito net chemical coatings impact performance, with PFAS-based coatings altering how well a net works. The study suggests integrating conventional bioassays with surface chemistry and behavioral analysis to strengthen product development and regulatory evaluation.
A large regional species pool, driven by favorable climates, varied habitats, and stable historical climates, supports both high diversity and many rare trees. Forests with larger species pools require prioritized protection to preserve forest diversity and save rare and endemic species from human disturbance.
A new cathode material with a dual-crystal-phase structure improves the performance and stability of aqueous zinc-ion batteries. The material offers high capacity, rapid charging capabilities, and exceptional longevity.
Researchers developed a high-performance catalyst using abundant materials, exhibiting superior oxygen evolution activity and remarkable stability. The novel design paradigm, achieved through heterojunction-doping synergy, positions it as a viable alternative to iridium-based catalysts.
A new study found that influenza was detected in 11% of winter deaths, but only 17% had a confirmed diagnosis before death. The study highlights the gap between detection and official mortality records, suggesting influenza may play a larger role in winter mortality than routine surveillance captures.
A new high-density 10K SNP array for wax gourd has been created using GBTS technology. The array was used to analyze genetic distances among elite inbred lines and commercial cultivars, revealing two major groups with distinct population structures.
A new study introduces NARA, a computational framework that combines firefly algorithm with uncertainty-aware machine learning to make atomic structure prediction more robust. The method achieves higher efficiency than the widely used basin-hopping algorithm and recovers competing structures in a single run.
Researchers at Hiroshima University have developed a new approach to predicting harmful algal blooms by coupling three models and accounting for plankton species interactions. This improved forecasting can help prevent economic losses and protect fish stocks in countries like Chile, which has been hit hard by these blooms.
Researchers have discovered a brood pheromone released by clonal raider ant larvae that temporarily suppresses egg-laying in adult ants. The pheromone, MEHMP, is produced exclusively by larvae and helps synchronize brood care and reproduction in the colony.
A new optical-coupled scanning probe microscope uses a remote liquefaction cryogen-free system to visualize individual atoms and probe electronic and chemical properties without freezing budget. The system achieves stable base temperature and low noise levels, making it ideal for continuous experiments and studies of slow processes.
The Journal of Fast-Track Health will publish original research on global health challenges, including communicable and non-communicable diseases. The journal aims to bridge the gap between urban and national health responses through rigorous science and practice-oriented approaches.
A rapid and visual on-site detection system for Epizootic Hemorrhagic Disease Virus (EHDV) has been developed based on RT-ERA and CRISPR-Cas12a. This system achieves high sensitivity and specificity, making it suitable for point-of-care testing in field settings.
Enzyme-based glycan editing allows dynamic remodeling of N-glycans on living cells without compromising function. Recent breakthroughs include targeted tumor therapy and dual-transferase engineering of immune cells, highlighting the potential for precision glycobiology in immunity, cancer, and development.
Researchers developed a novel 'steric hindrance' strategy to create advanced single-atom catalysts outperforming traditional platinum benchmarks. The bulky metalloporphyrins provide spatial shields around metal centers, preventing agglomeration and ensuring high-performance in oxygen reduction reactions.
New research proposes that rock grains bond together at microscopic contact points, governing friction and stress release during earthquakes. This finding challenges existing models and suggests tectonic plates behave differently than previously assumed.
A study by researchers at the University of Gothenburg found that children born before 24 weeks of gestation incur significant societal costs, peaking in the first year of life. The need for support persists long after initial care, with severe complications often leading to more extensive and long-term support needs.
A new analysis of satellite data shows that global nighttime lighting is increasing by about 2% per year, despite regional fluctuations. In Europe, nighttime light emissions declined by 4% overall, but increased in China and India due to urbanization.
A new AI framework corrects forecast biases, achieving a 20% reduction in root-mean-square error for air temperature forecasts. The model supports bias correction of oceanic variables, enhancing forecast accuracy in meteorological and oceanic scenarios.
A new study from Finland shows that sauna bathing releases white blood cells into the bloodstream, playing a key role in the body's defense against pathogens and diseases. This periodic release of white blood cells is beneficial for immune defense.
Researchers developed a new imaging technique that captures both intensity and phase changes of an object in a single measurement. This allows scientists to observe ultrafast phenomena with unprecedented detail and speed, enabling the study of materials, biological processes, and high-power laser technologies.
A study of over 1500 patients with brain bleeds found that brain swelling in the first 24 hours and within 72 hours increased the risk of death or disability. Early intervention could potentially limit brain damage and improve recovery after stroke.
Four Ontario-based research teams are receiving funding to develop next-generation cancer therapies with improved efficacy and reduced side effects. The projects focus on breast and ovarian cancers, a hard-to-treat form of leukemia, and a 'master regulator' protein involved in many different cancers.
The study found that the MDGA1 protein modulates brain neural circuits and its mutation leads to over-excitation. Administering bazedoxifene restored normal behavior in male mice with autism-like behaviors.
A research team at DGIST has discovered a mechanism to treat dementia by regulating brain immune cells. Somatostatin, a neurotransmitter, prevents the overactivation of immune cells and restores their protective role in removing waste from the brain.
Researchers engineered pak choi with a chimeric protein targeting glycolytic enzymes to flavonoids biosynthesis, resulting in intensified sweet flavors. This breakthrough offers a blueprint for sustainable flavor improvement through metabolic engineering.
A study by IRB Barcelona researchers sheds light on the regulation of protein production in fatty liver cells, revealing a key role for CPEB4 in controlling gene expression. The findings provide new perspectives on the disease and its progression towards more severe forms.
Researchers at Insilico Medicine have developed novel small molecular inhibitors and extremely selective PROTACs targeting the serine/threonine kinase PKMYT1. The discovery utilizes noncovalent interactions to achieve selectivity, masking hydrogen-bond donors that negatively affect permeability and solubility.
Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development in mice. A single-letter insertion in a non-coding regulatory region caused XX mice to develop as males with testis and male genitalia.
The ACP's 2026 Internal Medicine Meeting will gather over 5,000 clinicians and experts to explore cutting-edge research and innovations in patient care. Keynote speaker Ashish K. Jha, MD, MPH, will discuss clinical leadership and trust in the age of information chaos.
Researchers have developed a novel all-optical method called laser optothermal nanobomb (LOTB) for efficient flattening of nanobubbles in 2D materials. The method leverages an optothermally induced phase transition and stress-pulling effect to remove gas from the bubbles, flattening the film without damaging its intrinsic properties.
Researchers have discovered high levels of forever chemicals like PFAS in Svalbard reindeer, while toxic metals such as cadmium and lead have shown a decrease. The study suggests that PFAS levels have skyrocketed over the past decade, with implications for human consumption of the animals.
A new international research collaboration has developed lay descriptions to visualize the global burden of disease caused by facial pain. Facial pain affects everyday activities like eating and speaking, and is often long-lasting.
Researchers suggest that dark matter may consist of multiple particles, whose behavior varies depending on the cosmic environment. This could explain why a signal observed at the center of our galaxy is not seen in dwarf galaxies.
The Paranal solar ESPRESSO Telescope (PoET) has made its first observations, aiming to understand how stellar activity affects the detection of exoplanets. PoET uses the Sun's light to analyze distant star spectra and remove 'noise' that can mask planetary signals.
A new study by the University of Eastern Finland highlights the challenges faced by older immigrants in Finland when seeking social and healthcare services. The study found that lack of language skills, incorrect diagnoses, and discriminatory practices hinder their access to employment and citizenship. Improving interpreter services, p...
Researchers at Osaka Metropolitan University discovered that dragonfly visual protein detects red light similarly to mammals. This finding has potential applications in medical fields relying on red light-sensing, such as optogenetics.
Soft robots could work as medical implants, deliver drugs inside the body, and explore dangerous environments. The researchers designed a reconfigurable robot that can move repeatedly without degradation, using targeted heating to control motion and embedded temperature sensors for closed-loop control.
A new paper warns that halting and reversing biodiversity loss by 2030 is urgent to avoid destabilizing the Earth's vital systems. The authors call for a unified 'Nature Positive' approach to global environmental goals and governance.
Nancy L. Lewis, MD, MBS, FACP, a renowned biomedical researcher and clinical trials expert, has been appointed as the new Chief Scientific Officer of the National Comprehensive Cancer Network (NCCN). She will oversee NCCN's programs to advance clinical trials and improve cancer care outcomes globally.
A new study reveals that two key BET proteins, BRD2 and BRD4, perform distinct roles in gene activation. Blocking both simultaneously disrupts the process, producing unpredictable effects. Targeted therapies may be more effective if they distinguish between these roles.
Researchers have discovered that native soil bacteria can degrade persistent pollutants like dioxins without genetic engineering. Using decoy molecules, the bacteria's natural enzymes are tricked into breaking down these toxic compounds.
Researchers generated a comprehensive view of DNA methylation abnormalities in human MDS HSCs, uncovering a novel TET2-GFI1 axis that suppresses malignant transformation. The study identifies key hematopoietic regulators and provides a panoramic view of DNA methylation disruption in MDS.
Experiment with 195 students in Germany found that local forest soundscapes had stronger positive effects on mental wellbeing, especially when participants felt familiar with the sounds. The study revealed that perceived animal diversity and familiarity played a significant role in triggering feelings of awe and restoration.
Researchers used theoretical modelling to explore graphene's interaction with TiO2, finding that defects lead to strong covalent bonds and hybridised electronic states. This enables efficient charge transfer and reduces electron-hole recombination, boosting photocatalytic performance.
A global study reveals treelines shift upslope in 42% of cases, retreating in 25%, due to complex interactions between temperature and human interventions like land use changes. Treeline dynamics also influenced by natural disturbances like fires.
Scientists at the University of Virginia Health System have developed a suite of AI-powered tools, called YuelDesign, YuelPocket and YuelBond, to transform how new drugs are created. These tools can design drug molecules tailored to fit their protein targets exactly, even accounting for protein flexibility.
Scientists have identified two non-coding genes as the cause of autoimmune neonatal diabetes in 19 children. The discovery sheds light on the importance of non-protein coding genes and their role in human disease.
Scientists at the University of Kent have found that madecassic acid inhibits the ability of antibiotic-resistant E. coli to grow, suggesting it could serve as an alternative antimicrobial. The study shows three modified variants of the compound effectively inhibited cytochrome bd and shut down bacterial growth.