The new centre supports multiple clinical trials in parallel, enabling comprehensive evaluations of organ health across physiological systems. It also provides hands-on training opportunities for healthcare professionals, bridging the gap between theoretical knowledge and practical application.
A new study from Trinity College Dublin finds that dexamethasone can reduce inflammation in TB patients while enhancing the function of their macrophages to kill Mycobacterium tuberculosis. The research suggests using steroids as an adjunct therapy in conjunction with existing treatments, particularly in cases with excessive inflammation.
NTU Singapore's partnership with the Millennium Technology Prize expands its global network and strengthens its mission to recognize technological innovations. The prize recognizes breakthroughs that address global challenges and improve human wellbeing.
Researchers from the University of South Australia explore the connection between the gut and brain to decipher their role in mental health and wellbeing. The study found that changes in the gut microbiome can directly affect brain chemistry, suggesting a potential link between gut health and mental illness.
Scientists have discovered a surprising strategy plants use to thrive in sulphur-deficient conditions by releasing glutathione, which enhances plant growth but reduces bacterial growth. This 'trans-kingdom fitness trade-off' has implications for designing better microbial solutions for resilient crops.
Denis Evseenko and Toby Maher are developing a regenerative drug to block cells that promote fibrosis in the lungs, aiming to slow or reverse IPF damage. The team plans to test the safety and therapeutic potential of their drug-like molecules in animals and human cells.
A collaborative team at Scripps Research is creating the first atlas of interoception, a process by which the nervous system monitors physiological signals to maintain vital functions. The team aims to build a comprehensive framework for mapping internal sensory pathways using $14.2 million NIH funding.
A study analyzing S. macrophylla's natural populations in Kalimantan revealed distinct genetic structures among northeastern, central, and southwestern populations. The ancestral population shows highest genetic diversity and is recommended for conservation as a separate management unit.
The East Asian Summer Monsoon has shaped the genomic evolution of Engelhardia species through significant variations in genome size and gene number. Phylogenomic analyses reveal divergence between evergreen and deciduous lineages around 52 Mya, coinciding with EASM intensification.
The research emphasizes the importance of coordinating China's multi-level carbon markets in the context of global carbon pricing. Local pilot markets are seen as experimental fields for innovation, covering small enterprises and promoting regulatory experimentation.
Researchers developed a multiphysics model that couples electrochemical and mechanical dynamics in all-solid-state batteries. The model enhances interfacial stability and lithiation kinetics by regulating electrochemical potential gradients.
Researchers have developed a novel electrolyte design for potassium-ion batteries using fluorinated triethyl phosphate, enabling fire-retardant and high-performance electrodes. The electrolyte supports reversible potassium storage in graphite anodes and addresses key barriers in PIB commercialization.
Researchers developed DeMemSeg, an AI-driven pipeline that accurately segments overlapping membrane structures with accuracy comparable to expert manual analysis. The approach enables large-scale, objective, and quantitative analysis of morphological data, providing a foundational technology for advancing disease mechanisms.
Researchers analyze the 'dead Mn' dilemma in MnO2 chemistry, proposing strategies to enhance electrochemical reversibility and cycling stability. Mitigation approaches include optimizing deposition conditions, regulating proton supply, and reactivating inactive species using redox mediators.
Researchers at University of Tsukuba predicted the intensity of 21-cm radio signal in different dark matter models using numerical simulations. The results imply hydrogen gas produced a characteristic signal that could reveal dark matter mass and velocity if detected globally.
A recent study published in Medical Research Archives found that incorporating canned beans into a diet reduces shortfalls in essential nutrients and improves overall diet quality among U.S. adults. The research also highlighted the impact of replacing high-protein foods with canned beans on achieving optimal nutrient intake.
Research finds primary caregivers in urban under-resourced communities highlight the importance of parent input to boost equitable access to out-of-school-time activities. Key strategies include broad outreach, structural investments, and family engagement to improve participation and quality., The study suggests that enrichment and re...
A new study by University of East Anglia finds that housing associations are more effective than government work programmes at helping the long-term unemployed in deprived areas. The research suggests a person-centred approach with strength-based and long-term support is key to success.
A new study found that cognitive performance peaks during ovulation, while physical activity level has a greater influence on brain function. Reaction times are faster and errors are lower when active compared to inactive women, with a difference of around 70 milliseconds.
Low to moderate-severity fires boost bird populations with effects lasting up to 35 years, contrary to traditional fire suppression practices. Forest managers can use controlled burns and pyrodiversity to benefit majority of birds in the forest.
A global study found that biochar significantly reduces methane and nitrous oxide emissions in composting, while conserving nitrogen and stabilizing carbon. The optimal amount of biochar added is critical, with 10-20% achieving the strongest reductions.
The Brain & Behavior Research Foundation recognizes five leading psychiatric researchers for their groundbreaking work on mental illness. The award winners will present their cutting-edge research at the BBRF International Mental Health Research Symposium in October 2025.
Researchers at William & Mary's Batten School and VIMS have successfully restored bay scallop populations to their former range along the Eastern Shore of Virginia, with an average density of 0.114 scallops per square meter. The population is expected to double in less than 1.5 years, potentially leading to a future recreational fishery.
The Brain & Behavior Research Foundation hosts a free, public event featuring research presentations on various mental health topics. Attend in-person or virtually and register now to attend the symposium.
A new study reveals that multitasking makes phishing detection harder, but introducing brief reminders can significantly improve accuracy. Researchers found that working memory load and message framing cues affect detection performance.
Neli Ulrich, a leading epidemiologist, has been elected as vice president and president-elect of the AACI Board of Directors. She will serve for two years before assuming the presidency of the organization, with a focus on advancing cancer research, prevention, and care.
Researchers at Stanford University have solved the famous Poisson model for heterogenous materials, enabling the design of stronger, cheaper materials. The new approach uses a statistical method to predict material properties based on random point knowledge.
This study investigates the effects of polyherbal supplement MD-1 on high-fat diet-induced diabetes in C57BL/6J mice. MD-1 treatment significantly reduces blood glucose, triacylglycerol, and total cholesterol levels, improving adipose tissue function.
During the 2024 total solar eclipse, researchers discovered that bird species sing as if it were dawn, even when only dark for four minutes. The study used a smartphone app and automated recorders to collect data on over 100,000 bird vocalizations, revealing 29 species showed clear changes in behavior.
Research reveals that the April 2024 total solar eclipse disrupted bird behavior, with some species bursting into song after the Sun returned. The study, combining citizen science and machine learning, found that the temporary darkness reset birds' biological clocks, prompting them to behave as if a new day had begun.
Researchers have unraveled the structure of two key malaria parasite proteins, offering opportunities for new vaccines that block mosquito transmission. The discovery is a significant step towards eradicating the deadly disease.
Researchers at Università Cattolica del Sacro Cuore develop immersive VR experiences mimicking psychedelic substances' effects on cognitive and emotional processes. The study shows significant effects on flexibility, creativity, and emotional state, with potential for integrating cyberdelics into therapeutic protocols.
Recent research from the American Meteorological Society reveals a false global heat record, suggests that severe weather events are increasing in frequency, and predicts an expansion of fire-prone areas. The study also examines the impact of cold wakes on tropical cyclone rainfall and finds that they intensify with global warming.
Researchers monitored new-onset atrial fibrillation after CABG to assess long-term risk and guide treatment recommendations. The study found very low AF burden in patients, challenging current guideline recommendations for oral anticoagulation.
Researchers at Harvard Medical School developed Dr. CaBot, an AI system that can generate a differential diagnosis and explain its nuanced reasoning like an expert diagnostician. The system reached a comparable final diagnosis to a human expert in a published case presentation, demonstrating its potential for medical educators and phys...
Researchers developed a new gene therapy that reversed symptoms related to SYNGAP1-related disorders in mice, including intellectual disability, epilepsy, and risk-taking behaviors. The therapy successfully delivered a working copy of the SYNGAP1 gene into brain cells using an adeno-associated virus, offering hope for treatment in humans.
Researchers at the University of Tokyo developed an AI-based framework, scHDeepInsight, to rapidly and consistently identify immune cells from gene data. The system uses hierarchical learning and image-based representation to distinguish broad and fine subtypes with improved accuracy and consistency.
A new pilot project by Frankfurt University Medicine and Münster University Hospital has shown that deep brain stimulation can significantly reduce stuttering frequency and severity. The treatment, which involves implanting a thin wire into the left thalamus of the brain, was found to decrease stuttering by 46% in one patient.
A report by Digital Science assesses Australia's National Persistent Identifier (PID) Strategy, highlighting strengths and weaknesses. The study recommends improving data citation and ORCID adoption for non-traditional research outputs.
A new lab-designed protein has been discovered to regulate blood glucose levels, offering a potential new treatment avenue for people with Type 1 diabetes. The substance combines insulin and glucagon into one molecule, signaling the liver to respond naturally.
A study on C. elegans reveals that dissolved biochar affects nematode growth and physiology, with lower doses promoting development and higher doses disrupting normal functions. The findings highlight the need for careful dosing and oversight when deploying biochar in agricultural systems.
The American Heart Association's Periodic Table of Food Initiative data visualization challenge aims to translate complex biomolecular information into actionable insights. Participants will create compelling visualizations that reflect nutritional quality, molecular diversity, sustainability impact, or cultural relevance.
The study identified chemical compounds that precisely block the interaction between RAS and a key pathway for tumour growth. The treatment has entered its first clinical trial in humans and has shown promising results, with potential to treat many different types of cancers while avoiding effects on healthy cells.
Genomic sequencing in newborns has been shown to detect hundreds of treatable conditions, including childhood cancers, cardiac disorders, and neurological issues. The test was found acceptable to parents and feasible using the same sample collected for the heel-prick test.
According to the BfR Consumer Monitor, only 10% of respondents expressed concern about raw milk's health risk. Raw milk can transmit pathogens, posing a risk to vulnerable populations such as children, pregnant women, and the elderly. Healthy adults also face an increased risk of mild to severe food poisoning from unboiled raw milk.
Angelo Forli's research project aims to investigate the hippocampus, a key region for memory and learning, to understand its mechanisms and adaptability. His team will explore how neural networks regain control of regenerated organs and develop new technologies inspired by brain's 'regenerative intelligence'.
A Dutch study found that vaccination coverage among children declined faster in households with lower income and those not attending daycare. The study, which analyzed over 2 million children, identified sociodemographic factors contributing to the decline, including parental education and migration background.
A nationwide analysis found that emergency Medicaid accounted for less than 1% of overall Medicaid spending in states with large undocumented populations. States with larger undocumented populations spent more per capita, but still faced minimal cost savings from cuts to emergency Medicaid.
Poor blood sugar control in adolescence increases the risk of painful future complications for people with type 1 diabetes. Children diagnosed with type 1 diabetes at a young age have trouble controlling their blood sugar as teens and are more likely to develop neuropathy in adulthood.
China's emerging AI regulation aims to balance oversight with openness, fostering collaboration and long-term innovation. The country's Model AI Law and Scholar's Proposal are key references for ongoing policy discussions, with a focus on exemptive laws, efficient adjudication, and experimentalist requirements.
A new study published in PLOS One found that running with a stroller reduces vertical loading metrics by up to 17%, potentially decreasing injury risk. However, torsional loading metrics increased significantly, posing a potential trade-off.
A new study analyzes 52 REDD+ initiatives certified under Verra's Verified Carbon Standard, finding widespread over-crediting of projects and only a minority meeting their reported emissions targets. However, the research suggests that even underperforming projects can deliver partial climate gains when implemented carefully.
A new study reveals that true crime media can be both a help and a hindrance to co-victims, with many experiencing a loss of privacy and trauma due to sensationalized coverage. The research highlights the need for ethical production practices and standards to protect co-victims from harm.
Researchers at UMass Amherst have developed a nanoparticle-based vaccine that prevents melanoma, pancreatic and triple-negative breast cancer in mice. The vaccine achieved remarkable survival rates, with up to 88% of vaccinated mice remaining tumor-free.
A new study reveals that greater noctule bats capture and consume migrating birds in flight, employing unique aerial handling techniques. The bats use echolocation to spot prey, then execute high-speed chases before capturing their quarry, often consuming it during prolonged flights.
Researchers developed an AI-based generative approach to discovering technology opportunities from patent maps using machine learning. The system translates patent vacancies into human-readable text, enabling the identification of untapped technologies and facilitating innovation forecasting.
A novel framework integrates Kolmogorov–Arnold networks with dynamic predictor pruning optimization to improve TC intensity prediction. TCI–KAN achieves superior accuracy in 6-h intensity forecasts, outperforming referenced best records by 31%, 13%, and 6%. The model's accuracy varies by region and TC category.
A new study has mapped thousands of proteins in human blood to reveal unique molecular fingerprints for each individual. This atlas will enable blood tests to distinguish troubling signs from common ones, and provide a baseline for comparison that healthcare providers can use to flag early deviations.
A novel disease prevention strategy targeting the Aedes mosquito species has been shown to reduce mosquito numbers by 60% and cases of dengue fever by 24% in a community. The study, conducted in Merida, Mexico, tested an intervention that used targeted indoor residual spraying of insecticide before outbreaks occur.
Researchers developed a bio-inspired dual-amplified patch that accelerates and enhances the uniform delivery of extracellular vesicles (EVs) through the skin. The innovative patch uses short microneedles to overcome the stratum corneum barrier, enabling pain-free transdermal delivery of EVs.
A new study by the University of Arkansas System Division of Agriculture reveals that water quality can significantly impact the type of microbial populations in poultry drinking water lines and litter. The study found a Bacillus species with probiotic properties was more prevalent in biofilms from poultry houses with normal sulfur-iro...
Research reveals that ovarian aging is not just about egg quality, but also the surrounding cells and tissues. The study found that eggs cluster in pockets surrounded by egg-free zones, which decline in density with age, influencing egg lifespan and maturation.
FastTrack uses machine learning force field and 3D PES sampling to predict atomic migration barriers accurately within minutes, overcoming limitations of traditional methods. It enables quantitative high-throughput screening of ion transport across vast material spaces.
Research by UPF reveals that people with Arabic and Chinese names receive fewer positive responses as buyers but are not rejected as sellers. They should offer up to 3% more to be treated equally. In contrast, minority sellers do not suffer significant discrimination.
A WSU-led study shows firearm-related deaths are increasing dramatically among high school youth, with 3,224 deaths in 2022 compared to 1,945 in 2001. The research highlights the need for adapted firearm safety guidance tailored to developmental stages.
Researchers propose a new model for Earth's oxygenation, finding that high nickel and urea concentrations kept cyanobacterial blooms rare. As these compounds became available at lower levels, they drove the expansion of cyanobacteria, leading to long-term oxygen release and the Great Oxidation Event.
Scientists at the University of Cambridge have developed a pioneering biosensor that can detect and track salicylic acid dynamics in living plants. The SalicS1 tool provides fresh insights into how plants coordinate local and systemic defenses against pathogens, with potential applications for improving crop resilience and understandin...
Scientists observed tiny but spontaneous distortions in the crystal lattice of Cu_xBi_2Se_3 as it entered a superconducting state. This marks the first clear evidence of a topological superconductor coupling to the crystal lattice, advancing understanding of exotic electronic states.
Researchers identified a previously unknown gene, SMARCAL1, that increases the risk of developing osteosarcoma in children and young adults. The study found that approximately 2.6% of children with osteosarcoma carry inherited mutations in SMARCAL1, which may weaken DNA repair and promote tumor growth.
Researchers have developed a high-performance supercapacitor made from upcycled water bottles, demonstrating improved capacitance and reduced production costs compared to traditional glass fiber separators. The PET-derived supercapacitor is fully recyclable and poised for market-ready devices within the next five to 10 years.
Ochsner Health's Genetic Wellness Assessment is an innovative screening tool that helps identify individuals at risk for hereditary cancers. The assessment evaluates personal and family history to provide personalized cancer screening and prevention plans.
The ASHG 2025 Annual Meeting will highlight advancements in rare disease research through long-read sequencing and collaboration. Genetic mechanisms of cancer risk and the clinical impact of latest epilepsy neurogenetics advances will also be showcased, along with decoding human aging and AI-powered genomics.
A new approach called Streamlined Life Cycle Assessment (SLCA) uses AI, 3D modeling, and secondary databases to assess a product's environmental footprint. SLCA cuts the time required for assessments from months to just one week, while maintaining accuracy.
Research published by the American Psychological Association found that short exposure to inspiring media can reduce stress and increase hope. Participants who watched inspirational videos or followed guided meditations reported feeling more hopeful and experiencing lower stress levels than those with no media use instructions.
A study published in Annals of Neurology reveals a genetic connection between errors in the EPG5 gene, which causes Vici syndrome, and Parkinson's disease. Researchers found that individuals with rare errors in EPG5 were more likely to develop Parkinson's disease and dementia.
Researchers have solved the puzzle around protein distribution in plant cells by discovering a phosphoinositide-mediated switch that regulates the Guided Entry of Tail-Anchored proteins (GET) pathway. This mechanism highlights the dynamic interplay between lipids and proteins in shaping cellular membranes.
A council of five AI models trained to deliberate together achieved higher accuracy on medical licensing exams than any single chatbot alone. This collaborative approach showed promise for improving the reliability and trustworthiness of AI tools in healthcare.
SourcePLOS·JournalPLOS Digital Health·TypeComputational simulation/modeling·DateOct 9, 2025
Thick-film organic photovoltaics (OPVs) hold promise for high-efficiency, scalable, and cost-effective solar cells. The study establishes guidelines for designing high-performance OPVs by bridging the gap between laboratory achievements and industrial manufacturing.
The European Space Agency's (ESA) Plato spacecraft has been completed with the installation of its sunshield and solar panels. The spacecraft is now set to undergo a series of tough exams before its planned launch in December 2026 on an Ariane 6 rocket.
Scientists have developed an end-to-end microbial process converting renewable plant oils into sustainable polyesters comparable to petroleum-based plastics. The two-step process achieved record-setting yields and productivity, paving the way for a scalable and environmentally viable alternative to fossil fuels.
A team of researchers analyzed teeth from five archaeological sites in the Euphrates Valley, revealing that early farming communities were inclusive and open to newcomers. Women were found to be more likely than men to move between communities, possibly to avoid inbreeding.
Researchers at City of Hope have identified a potential strategy to overcome treatment resistance in acute myeloid leukemia and uncovered racial disparities in triple-negative breast cancer. By targeting the ALKBH1 protein, which enhances energy production in cancer cells, scientists found that blocking this protein could make CAR T th...
In a study published in PLOS Biology, researchers found that young European great tits learn essential life skills from their older siblings and non-parental adults, rather than primarily from their parents. This suggests an alternative pathway to cultural inheritance and highlights the importance of sibling relationships in shaping bi...
A recent study by Waseda University researchers reveals that the Bank of Japan's large-scale ETF purchases have a significant impact on both the equity market and securities lending market, making short selling easier. This suggests that the stock market functions efficiently to some extent, mitigating distortions in stock prices.
A study of 105 dogs found that 33 exhibited compulsive engagement with toys despite negative consequences. Dogs showed excessive fixation on their toy, lack of interest in alternatives, and inability to calm down after toy removal.
A new study on Mars crater deposits reveals the planet went through repeated ice ages driven by shifts in its axial tilt, resulting in a gradual drying of the planet. The study provides insights that can be applied to Earth's changing environment and helps identify safe regions for future missions.
Researchers found sustainable solutions in food waste for farming and pharmaceuticals, including bioactive compounds from millipede-digested coconut fibers. The American Chemical Society published four papers detailing these discoveries, providing new sources of materials for industries.
The 17th World Congress on Targeting Mitochondria will gather world's leading experts from biotechnology, pharma and academia to discuss health, longevity and precision medicine. Over 150 academic and institutional partners and 30 industrial and investment organizations are participating.
Researchers show low-molecular-weight kraft lignin restores insulin sensitivity and slashes blood glucose levels in diabetic rats. The fractionation process is simple, scalable, and cost-effective, positioning lignin as a renewable and non-toxic active ingredient for functional foods or therapies.
A new study warns that dental shame can lead to lower self-worth and unfavourable oral health care behaviours, exacerbating existing oral health inequalities. Researchers emphasize the need for non-judgmental environments where patients feel empowered to prioritize their oral health.
A genetic mechanism called diversity-generating retroelements accelerates evolution in gut bacteria, allowing them to adapt to new environments. This mechanism is more common in the gut microbiome than any other environment on Earth and enables microbes to change and adapt rapidly.
The PLD-REBCO industry has seen rapid development thanks to commercial compact fusion, enabling mass production of high-performance REBCO tapes with excellent in-field performance. However, challenges remain, including reducing costs and improving scalability, which require closer collaboration between industry and academia.
A study led by Julie Pilitsis, MD, PhD, found a possible connection between chronic pain and eosinophilia, a white blood cell condition, in patients undergoing spinal cord stimulation or implanted pain medicine pumps. The study suggests that eosinophilia may be an immune biomarker for chronic pain.
A 4-week intervention study found that adhering to UK Physical Activity Guidelines improves cardiorespiratory fitness and increases muscle thickness and strength in older adults. This study demonstrates the potential of physical activity guidelines for improving health and functional well-being in older adults.
A large-scale analysis of existing research finds that school-provided social and emotional learning programs improve students' academic achievement in addition to their social and emotional development. The study also highlights the importance of program duration and universal SEL instruction in schools.
Researchers from Australian National University have detected binary stars in the outer regions of 47 Tucanae, a globular cluster in the Milky Way. This discovery sheds light on how these clusters formed and evolved over billions of years.
Researchers found that quitting smoking more than doubles survival time among patients with advanced cancers. The study shows the benefits of integrated smoking cessation interventions into cancer treatment plans.
Long-term exposure to fine air pollutants like PM2.5 can impair metabolic health by disrupting the normal function of brown fat through complex epigenetic changes. The study identified two enzymes, HDAC9 and KDM2B, as key drivers of this process.
New research by Bayes Business School reveals the introduction of the National Living Wage has decreased labor mobility across firms, but its impact on workers' incentives to search for new jobs is unclear. The study suggests that rising wage floors may reduce job switches and make potentially risky job moves less attractive.
The AIM-HI Accelerator Fund has selected two companies, ResNovas Therapeutics and Chiara Biosciences, as winners of the 2025 Venture Competition. Both companies have demonstrated innovative approaches to targeted protein degradation and drug discovery, with potential to transform cancer treatment.
Researchers developed a refined analytical computational model for electromagnetic forces in HTS maglev systems, offering fast computation speed and clear parameter relationships. This enables comprehensive optimization and enhancement of the levitation system, reducing reliance on rare-earth permanent magnets.
Researchers found that patients with stage III or IV cancer who quit smoking lived significantly longer than those who continued smoking, with a two-fold lower rate of all-cause mortality. The study's findings emphasize the crucial role of smoking cessation support as part of standard cancer care.
A team of astronomers has discovered a mysterious dark object in the distant universe with a mass about 1 million times that of our Sun. The discovery is significant as it could confirm or refute theories about the nature of dark matter.
The Golden Goose Award recognizes federally funded research that unexpectedly benefits society, such as the development of cisplatin for testicular cancer treatment. The award also honors scientists who have made significant contributions to disease diagnostics.
A team of scientists at Heidelberg University has discovered a protein complex in chloroplasts that triggers the closure of microscopic pores on leaves to prevent water loss. This hormone, abscisic acid, is formed via biosynthesis and ensures plant survival during extreme drought conditions.
PhD candidate Jonah Branding's work provides a framework for evaluating animal consciousness, distinguishing between symmetry and asymmetry approaches. The study highlights the importance of considering hermit crabs as a case example to navigate complex questions about animal welfare and conservation policy.
Leading German business schools ESMT Berlin, Mannheim Business School, and WHU – Otto Beisheim School of Management have launched a joint initiative to bring greater international attention to Germany's advantages in science and education. The initiative aims to emphasize the country's affordable study programs, reliable structures for...
A.J. Jacobs will discuss strategies for communicating nuanced scientific information and building trust with the public. The event aims to foster excitement around research and evidence-based practice.
Researchers found that a high-fat, low-carb ketogenic diet can improve brain health and stop or slow cognitive decline in individuals with the APOE4 gene. This study suggests that precision nutrition tailored to an individual's genotype, gut microbiome, gender, and age may be more effective than a one-size-fits-all approach.
Plant functional diversity varies greatly depending on seasonal cycles and wet-dry periods, according to a new study that analyzed 4,000 satellite images. The researchers used AI algorithms to derive plant traits from the images and calculated quantitative measures of functional diversity.
This study found that TNF-α is highly expressed in asthma patients' airways and induces bronchial fibroblasts to produce inflammatory cytokines. The upregulated genes are closely related to eosinophil or neutrophil inflammation, indicating a role for bronchial fibroblasts in airway inflammation.
Researchers found that subtle changes in four amino acids of the naked mole-rat's cGAS enzyme enhance its ability to repair aging-related genetic damage. This allows for stronger interactions with repair factors, boosting HR repair and contributing to the species' extraordinary longevity.
Climate-driven oxygen loss can trigger expansion of microorganisms producing methylmercury, a potent neurotoxin. Ancient DNA analysis shows similar processes occurred in the past; modern warming oceans risk similar conditions.
A significant association was found between increased lung cancer incidence and higher reported exposure levels among World Trade Center (WTC) responders. Future studies will investigate specific exposures and histologic changes to clarify the role of WTC exposure on prognosis.
Using extreme ultraviolet high-harmonic interferometry, researchers tracked changes in the electronic bandgap of silica glass and magnesium oxide under strong laser excitation. The study found a shrinking bandgap in silica and a widening bandgap in magnesium oxide.
A new study found that implicit biases impact how much effort individuals, both autistic and non-autistic, put into charitable behaviors. While explicit biases were not a factor, participants showed self-bias in decisions, prioritizing their own efforts over others.
Researchers found that cancer cells in a tumor environment with acidosis can switch to more efficient energy production, using networks of mitochondria instead of fragmented structures. This adaptation helps cancer cells survive under adverse conditions, and could lead to new treatments targeting the energy metabolism of tumors.
This study found that aged rats living in socially enriched environments retained better memory and cognitive flexibility than those housed alone. Socially housed rats showed increased activity in the hippocampus and reduced overactivity in the anterior cingulate cortex, suggesting a more balanced and efficient neural response.
A new system developed by researchers at Nagoya University can detect genetic mutations in brain tumors with high accuracy and speed. The system successfully identified key markers for diagnosis of diffuse glioma, a common type of brain tumor.
Researchers have found that GLP-1 therapies may help reduce alcohol and other substance use by modulating neurobiological pathways underlying addictive behaviors. The therapies, which are commonly used to treat diabetes and obesity, have shown encouraging results in early clinical trials.
Researchers found that songbird juveniles rely heavily on their siblings and other adults for learning life skills when parental care is limited. In contrast, only about 25% of young birds learned to solve feeding puzzles from their parents.
Researchers have developed a novel imaging technique to visualize Toxoplasma's endocytosis process. The parasite actively recycles its membrane by absorbing parts through micropores and reusing them for daughter cells.
Astronomers have captured the first-ever radio image of two black holes orbiting each other at the centre of a quasar called OJ287. The observation confirms the existence of black hole pairs and provides insight into their orbital motion.
The MetaGraph digital tool enables fast and accurate searching of vast DNA sequence datasets, streamlining genetic research. By indexing raw data with metadata, researchers can identify specific mutations and rare hereditary diseases in patients, accelerating discoveries in fields like antibiotic resistance.
Researchers at MIT have found a hidden atomic order in metals that changes their properties, including mechanical strength and heat capacity. The discovery reveals a new physical phenomenon explaining the persistent patterns and provides a simple model to predict chemical patterns in metals.
Researchers at Texas A&M University have developed a new framework to protect industrial processing facilities from cyber threats. The framework identifies vulnerabilities, detects abnormal activity in real-time, and provides safeguards and mitigation strategies to maintain safe operations.
A new global standard has been established to harmonize outcomes measurement in dengue treatment trials, addressing a longstanding discrepancy that limits the comparison of evidence. The initiative aims to accelerate the development of treatments for dengue fever and improve clinical guidelines, with input from experts worldwide.
A team of researchers has shed light on how Europe's largest bat hunts and consumes small birds. The bats use loud and low-frequency ultrasound echolocation calls to detect prey at great distances, then pursue it in steep dives towards the ground, catching and eating birds in mid-air.
The International Society for Stem Cell Research (ISSCR) has released a comprehensive guide to accelerate the translation of human pluripotent stem cell-derived therapies into clinical trials and commercial use. The guidance outlines key principles and decision points for developing safe, effective, and regulatory-compliant products.
Researchers found compound drought-heatwave events rippling and persisting through the night, exacerbating heat-related health risks. Soil dryness plays a key role in triggering these extreme events, which can affect crops, wildfires, and daily life.
Researchers developed a portable sensor to detect synthetic cannabinoids in e-cigarette liquids and biological fluids, allowing for early intervention and harm reduction. The device shows high selectivity and sensitivity, detecting concentrations as low as 0.2 µM and identifying specific peaks that quantify substances present.
Researchers designed proteins with autonomous decision-making capabilities, controlling their localization based on environmental cues. This breakthrough enables more finely targeted drug delivery, reducing off-target effects and improving therapy efficacy.
A new study reveals that fossil fuel companies are failing to invest in renewables, with only 20% owning an operational project and renewable energy representing just 0.1% of their primary energy extraction.
Researchers at Washington State University found that early planting to avoid heat damage may actually hinder spring wheat productivity due to other growth issues. The study used computer modeling to show that moving crop plantings earlier in the season can expose crops to elevated heat or cold stress in later growth stages.
Researchers discovered that adults can better access their early memories after embodying a childlike version of their own face. Participants who viewed their childlike faces recalled significantly more episodic childhood memories than those who saw their adult faces.
A study published in Aging Cell suggests that hormone replacement therapy (HRT) can help reverse changes in the immune system caused by menopause, leading to a healthier immune profile. Women taking HRT showed fewer inflammatory monocytes and stronger infection-fighting ability compared to age-matched controls.
A study published in Nature Geoscience found that North American ice sheets caused over 30 feet of global sea-level rise between 8,000 and 9,000 years ago. This discovery challenges decades of research and has significant implications for understanding climate change.
A nationwide survey in Japan revealed that patients have a strong desire for involvement in allergy research, but researchers often fail to engage. The study identifies key priorities for improving patient-centered care, including training programs and digital tools.
A key molecular player, RfaH, has been identified as a protective shield for bacterial genes, enabling them to survive the hostile environment inside the body. The protein ensures transcription runs to completion, making it an anti-terminator that prevents premature termination of gene expression.
A pioneering case of pig-to-human liver xenotransplantation has been successfully demonstrated, with the genetically engineered porcine liver functioning for an extended period in a human recipient. The patient survived for 171 days despite complications such as xenotransplantation-associated thrombotic microangiopathy.