Researchers at the University of Missouri-Columbia have discovered a protein, TG2, that contributes to arterial stiffening and inflammation linked to high blood pressure. By blocking TG2 activity, they found that inflammation can be reduced, potentially leading to more precise treatments for cardiovascular disease.
Dunpeng Cai is leading the search for a treatment for aortic valve calcification, a disease that affects millions of older adults worldwide and causes the heart's aortic valve to harden and narrow over time. His team plans to test a drug compound to slow or prevent the disease by blocking a protein called DOCK2.
Researchers found that enhancing autophagy, a cellular recycling process, helps preserve retinal nerve cells in glaucoma models. This approach may protect against cell loss and degeneration, potentially complementing current treatments.
Researchers found a simple scheduling change can improve sleep quality and biomarkers associated with inflammation in emergency medicine physicians. The earlier schedule helped align their sleep with the body's natural circadian rhythm, leading to measurable improvements.
Researchers from the University of Missouri discovered that the ratio of large and small stars in distant galaxies depends on their environment, potentially altering how scientists estimate galaxy mass and age. This breakthrough could lead to more accurate estimates and a better understanding of the universe's history.
A $1.15 million USDA grant is expanding the HotHog app, which predicts heat-related risks in pigs. The app provides location-specific forecasts and alerts to help producers prepare for extreme heat, improving animal welfare and production efficiency.
Researchers found that consistent daily routines lower pain and depression levels in older adults with insomnia. Maintaining a regular schedule helps synchronize the body's internal clock, leading to improved health outcomes.
Researchers at University of Missouri develop natural colorants from purple corn, showing stability and durability in various environments. The anthocyanins, rich in antioxidants, offer a viable path for food companies to create cleaner labels without sacrificing performance.
Researchers from University of Missouri-Columbia investigated mesenchymal-epithelial transition (MET) in the uterus, a process where cells rebuild the uterine lining after shedding. MET helps restore the uterine lining quickly, but its dysregulation can lead to inflammation, lesions, or cancer, potentially affecting fertility.
Researchers found that variable-rate seeding (VRS) can help farmers strike a better balance in corn and soybean fields. However, soybeans proved to be more complicated due to their adaptability to weather conditions. The study aims to make farming more accessible and efficient for small land holders using digital tools and data-driven ...
Researchers found that wood frogs' adaptation to salty water increases their vulnerability to ranavirus, a common and fatal disease. The study highlights the hidden costs of survival in wildlife under environmental stress.
A tiny parasite-carrying tick is posing a threat to Missouri's cattle, causing lethargy and weight loss in infected animals. Researchers analyzed DNA of collected ticks, finding that fewer than 1% carried the bacterium that causes bovine anaplasmosis.
A recent study from the University of Missouri-Columbia shows a potential way to protect transplanted islets without immunosuppressive drugs. Researchers engineered islets with thrombomodulin and CD47, which prevented harmful inflammation and allowed cells to respond to glucose naturally.
Researchers found that adding words like charming, cozy, or lovely to Airbnb listings boosted booking rates by roughly 0.2%, comparable to objective claims about amenities. The study's findings suggest that subjective praise can meaningfully shape consumer behavior without consumers feeling remorseful.
A new tool has been developed to identify blackouts during drinking, using objective memory tests that can detect blackouts in real-time. The study found a moderate correlation between not remembering an image while drinking and self-reported blackouts the next day.
Researchers at Mizzou's Molecular Imaging and Theranostics Center developed an automated approach to producing the prostate cancer treatment. The new method produces CTT1403 in just 38 minutes, compared to six hours with traditional methods, using a commercially available automated synthesis system.
Researchers found that amiloride, a common blood pressure medication, improves artery flexibility and lowers blood sugar levels in patients with obesity. The study suggests that amiloride could be a potential strategy to reduce arterial stiffening and cardiovascular risk in these patients.
University of Missouri researchers develop organic transistors that process information like biological neural networks, boosting brain-like computing and potentially leading to more energy-efficient artificial intelligence. The approach could lead to significant improvements in tasks such as pattern recognition and decision-making.
University of Missouri researchers developed an irrigation strategy that allows farmers to conserve water while maintaining crop quality. By tailoring water amounts based on plant growth stages, farmers can reduce water usage and costs.
Researchers have overcome epigenetic silencing to create genetically engineered chickens that can hatch with useful medical proteins. This breakthrough could lead to the development of stable lines of birds that lay eggs containing beneficial proteins.
Researchers developed a new flu vaccine approach targeting specific but distinct regions of the influenza virus protein. This method broadened the immune response, leading to broader protection against various strains. The study's findings have implications for fighting other fast-changing viruses like COVID-19 and RSV.
The University of Missouri is scaling up the use of virtual fencing, a cutting-edge agricultural technology that guides cattle to fresh grazing fields. With GPS-enabled collars, producers can save time and labor by eliminating physical fences, improving sustainability and profitability.
A new study from the University of Missouri identified over 10 genetic or molecular markers that predict follicular lymphoma relapse early, allowing for targeted surveillance testing. This could improve patient outcomes, reduce unnecessary imaging tests, and lower healthcare costs.
Researchers at the University of Missouri have found that the Amazon molly's ability to reproduce asexually is due to gene conversion, which preserves and repairs DNA inherited from both parent species. This process allows the fish to maintain genetic health despite millennia of cloning.
The University of Missouri is honoring three distinguished faculty members as 2025 AAAS Fellows. Paul de Figueiredo is being recognized for his contributions to microbiology, while Roman Ganta advances research on tick-borne diseases. Wesley Warren's expertise in genome-scale data analysis has reshaped research across multiple fields.
A study of 470 patients who underwent free flap reconstruction found that holding blood thinners for too long increases complications. The researchers suggest that resuming blood thinners within 48 hours after surgery may be safe, reducing the risk of excessive bleeding and dangerous clotting.
A recent study by Mizzou researchers found that some young adults with autism exhibit abnormalities in dopamine transporters on brain scans, which could be early biomarkers for potential Parkinson's disease development. This discovery may help identify individuals at greater risk and inform preventative measures.
A novel delivery method using microscopic lipid bubbles has successfully delivered a neuroprotective molecule to the brain, improving motor function in mice with ALS. The breakthrough could pave the way for human clinical trials to slow down or halt disease progression.
Alpha-gal syndrome is a growing concern in Missouri and beyond, causing delayed symptoms such as hives, stomach pain, and severe throat swelling. Mizzou researchers and MU Extension are working together to educate the public about alpha-gal syndrome and provide resources for those affected.
A University of Missouri study reveals that private dark pools attract inexperienced investors and allow companies to delay sharing bad news, increasing the likelihood of sudden stock price crashes. Dark pools also enable accounting manipulation by allowing managers to hide bad news through unusual accounting adjustments.
Researchers developed a free-to-use software tool, PSBench, to verify the accuracy of artificial intelligence-based protein structure predictions. The database includes 1.4 million annotated protein models, verified by experts, and provides reliable information for building more accurate AI systems.
Researchers at Mizzou's Bond Life Sciences Center have discovered how a specific protein known as SRFR1 regulates root growth in plants. They unlocked a way to manipulate this protein to encourage longer root growth, which can potentially help plants better withstand drought.
Research by University of Missouri scientists found that road salt is deadly to freshwater snails when paired with the presence of predators, causing nearly 60% higher mortality rates. The study suggests practical solutions to reduce salt pollution in waterways, such as cutting road salt use by up to 50%.
The University of Missouri has launched its first human clinical trial using Eye90 microspheres, a radiopharmaceutical breakthrough device manufactured on campus. The study aims to assess the safety and effectiveness of Eye90 in treating unresectable liver tumors, including hepatocellular carcinoma and metastatic colorectal cancer.
A three-year project utilizing GPS-enabled collars and mobile apps enables efficient rotational grazing, improving soil health and reducing farmer labor. Four Missouri producers have seen significant increases in cover crop utilization, with one producer reporting nearly double the value from the same acre of land.
Researchers have developed special algae that can remove and reuse harmful microplastics from wastewater, cleaning the water as it grows. The engineered algae produces a volatile natural oil called limonene, making it water-repellent and attracting microplastics, which can then be collected and reused to create bioplastic products.
A new AI-driven model predicts patient risk of suffering a major adverse cardiac event (MACE) with higher accuracy than traditional predictive models. This improvement in prognostic risk assessment could help personalize individual care plans and maintain quality of life for patients.
Researchers at the University of Missouri are developing AI models to accurately detect melanoma by analyzing images of skin abnormalities. The technology can help dermatologists identify cases that may require closer attention, leading to earlier treatment and improved health outcomes.
Researchers discovered that inhibiting a protein called RBM20 can improve heart filling and flexibility in mice with heart failure. The study also found positive impacts on energy metabolism, mitochondrial function, antioxidant balance, and blood flow.
A Mizzou researcher developed an antibody that attaches to and lights up EphA2 protein in cancerous tumors, allowing for non-invasive detection and identification of patients who can benefit from targeted treatments. This innovation could save time and money while advancing precision medicine.
Researchers identified nine objects with characteristics of stars and galaxies, sparking new questions about the cosmos. These 'platypus galaxies' have narrow emission lines indicative of active star formation, defying expectations.
Researchers found that male fish exposed to vitamin C and potassium perchlorate showed improved fertility and less damage to their testes compared to those exposed only to the chemical. The study suggests a potential safeguard for individuals regularly exposed to these chemicals, including military personnel.
A new AI-assisted device, CanvasDx, has been shown to improve autism care access in rural Missouri communities. By reducing travel distances and processing times, families can receive diagnoses up to 5-7 months earlier.
Raghuraman Kannan and Henry Nguyen, University of Missouri professors, have been elected National Academy of Inventors (NAI) Fellows. They were selected for creating or facilitating inventions that have had a tangible impact on society, with over 5,300 U.S. patents between them.
Researchers from the University of Missouri-Columbia have identified several genes that may be potential therapeutic targets for Chronic Kidney Disease (CKD) by regulating gene activity. These genes are involved in the signs of kidney damage, including fibrosis and inflammation.
University of Missouri researchers are combining in-home sensor technology with artificial intelligence to monitor daily changes in ALS patients' health. The system uses machine learning to estimate a patient's score on the ALS Functional Rating Scale Revised, predicting potential problems before they occur.
Researchers at the University of Missouri discovered that adding oil-based dressings or sauces to kale increases its carotenoid absorption. Cooking with these dressings is equally effective as mixing them in after cooking. The study suggests novel dressings could further boost nutrient absorption from other vegetables.
Researchers developed a 'humanized' model of aortic valve calcification, enabling testing of potential treatments. The breakthrough could lead to new therapies to stop or reverse calcium buildup, improving outcomes for people with heart disease.
A pilot program at University of Missouri-Columbia's emergency department connects rural families with community resources, improving their health and stability. Nearly half of participating families reported unmet essential needs, with food insecurity being the most common.
Researchers at the University of Missouri are exploring the use of extracellular vesicles to target lung cancer. By manipulating these tiny messenger particles, scientists can deliver specific instructions to kill cancer cells while sparing healthy ones.