A study by RIKEN researchers identifies a MYCN-driven biomarker that predicts the risk of liver cancer. The biomarker, known as the MYCN niche score, uses machine learning to analyze gene expression patterns and indicates whether a tumor-free liver is at high risk for developing tumors.
A new theory asserts that associative learning depends less on repetition and more on time passing between rewards, explaining why students who cram don't perform well. The study's findings could shift the way we look at learning and addiction, potentially speeding up artificial intelligence by borrowing from this new approach.
This method successfully solves the challenge of generating C,N,N-trialkyl α-amino radicals in aliphatic amides, enabling gram-scale reactions with low catalyst loadings. The reaction exhibits good functional group tolerance, making it suitable for late-stage modification of complex molecules.
The all-virtual Cal Poly Climate Solutions Now conference will address a wide range of climate topics, including energy, water, waste, business sustainability, agriculture, education, and more. Presenters from various industries will share strategies, tools, and information to help mitigate climate change.
A new Edith Cowan University study found that advertisements encouraging healthy choices can reduce cravings and intentions to consume unhealthy foods. In some cases, a 15-second message may be more effective than traditional 30-second commercials, especially for those with higher BMI categories.
A nationwide Japanese study of 270,000 patients found that widespread mask-wearing during the pandemic significantly lowered PM2.5-associated risk of MINOCA, a non-obstructive type of heart attack. The study suggests that simple protective measures like mask use can mitigate cardiovascular risks associated with air pollution.
In a new study, researchers at Uppsala University clarified family relationships in four graves from a 5,500-year-old hunter-gatherer culture at Ajvide on Gotland. DNA analyses suggest that the people were well aware of family lineages and that relationships beyond the immediate family played an important role. The analysis showed that...
A systematic review suggests that exercise has small, short-lived effects on knee osteoarthritis pain compared to placebo or no treatment. Moderate certainty evidence indicates negligible effects for hip and small effects for hand osteoarthritis. The findings question the universal promotion of exercise as a first-line treatment.
A long-term field experiment shows that combining biochar with compost and sludge can improve how sandy soils retain water, reducing cumulative drainage by over 40%. The triple combination of biochar, sludge, and compost formed a more stable soil structure that retained water more effectively than any single amendment alone.
A new low-energy method produces ethylene from waste gas, using electricity to create a chemical building block from syngas. The device is more than 60% efficient and can work with renewable energy sources, setting the stage for a greener ethylene supply chain.
Researchers report a significant association between muscle strength and lower mortality risk in women aged 63-99 years. Grip strength and chair stands were found to be key indicators of muscular strength, with even small improvements leading to notable reductions in death risk.
To meet basic copper demands, prices must rise substantially and mining processes need reforms. Recycling and alternative materials can alleviate some demand but may come with higher emissions.
A new study found that black carbon, a highly stable form of carbon, persists in mangrove sediments and enhances the climate mitigation potential of coastal wetlands. Mangroves store both organic and dissolved black carbon, which can travel through water and influence marine carbon cycles.
Researchers at Tongji University identified ferrihydrite as the mineral that effectively traps chromium while storing organic carbon. The study's findings provide a new blueprint for environmental remediation using nature-based solutions to clean up contaminated mine soils and fight climate change.
Researchers developed an oxygen-delivering gel to heal chronic wounds that fail to heal for more than a month. The gel conforms to the wound's shape and provides continuous oxygen levels, helping transform nonhealing wounds into normal injuries.
Researchers at Ohio State University Wexner Medical Center found that stellate ganglion block enhances the effectiveness of cognitive processing therapy for treating PTSD, leading to faster symptom reduction and improved outcomes.
A new study finds salcaprozate sodium may have adverse biological effects on the gut and beyond, including shifts in potentially harmful gut bacteria and elevated inflammatory markers. The research highlights an important gap in understanding the long-term impact of repeated SNAC exposure.
A team of astronomers led by UMass Amherst has discovered a population of dusty, star-forming galaxies at the edge of the universe, formed 13 billion years ago. These galaxies are linked to ultrabright, young galaxies and massive quiescent galaxies, providing new insights into galaxy evolution.
UCLA researchers have developed a novel gene-editing approach using lipid nanoparticles to deliver a full-length CFTR gene into human airway cells. The study shows promise for treating cystic fibrosis by correcting the underlying genetic mutation, which could lead to more effective and long-term therapies.
Dr. Zon's pioneering research has illuminated how blood develops in embryos, leading to a deeper understanding of rare blood diseases, including pregnancy complications. His discoveries have also led to breakthrough treatments for genetic blood disorders affecting babies and children.
The University of Pennsylvania School of Nursing will honor Diane Dodge with the 2026 Penn Nursing Renfield Foundation Award for her visionary leadership in addressing maternal health barriers. The award supports Tiba Foundation's efforts to scale the Boda Girls model, providing one million health services over five years.
A new study by Dr. Alex Gileles-Hillel and colleagues found that children with sleep apnea are twice as likely to contract the flu or COVID-19. The researchers suggest prioritizing annual vaccinations for these children to prevent severe respiratory complications.
A Cornell University study reveals that an existing FDA-approved drug, AMD3100, can prevent the sequestration of immune T cells from tumors, allowing them to attack cancer cells. The treatment shows promise for fibrolamellar carcinoma, a rare and fatal liver cancer with no cure.
University of Tennessee economist Charles Martinez recommends updating sales data reporting methods to account for the growing 'beef on dairy' trend. The trend involves breeding dairy cattle specifically for beef production, generating higher premiums for crossbred calves.
A new NIH study links maternal smoking during pregnancy to increased risk of hypertension and high blood pressure in children. The ECHO Cohort study examined the relationship between prenatal smoking exposure and childhood blood pressure.
A large cohort study found that air pollution exposure increases the risk of Alzheimer's disease, particularly in individuals who have experienced a stroke. The study suggests that improving air quality could be an important way to prevent dementia and protect older adults.
A team of researchers from North Carolina State University has created a new method to produce ultra-stretchable, superomniphobic materials using laser ablation. The materials can withstand extreme stretching and deformations while maintaining their liquid-repellent properties.
Researchers tracked individual honey bees to record high-resolution flight paths in natural landscapes, revealing precise navigation and unique routes. Visual landmarks aid the bees' navigation, increasing the precision of their flight paths.
Researchers developed a new method for extracting spectral information from OCT images and combining it with AI to identify lipid-rich plaques. The approach shows strong classification performance and can highlight suspicious regions throughout the image.
Researchers in Lund have presented a new model for cooperation that will shorten lead times and reduce costs. The Cell and Gene Therapy Navigator tool helps identify imbalances and future bottlenecks in projects.
The journal explores the convergence of computational biology, artificial intelligence, and healthcare innovation, with a focus on precision medicine and enhanced patient care. Submissions are accepted from researchers, clinicians, and technologists on topics such as AI in medicine, computational genomics, and drug discovery.
SeaCast consistently outperforms the Copernicus operational model over a 10-day forecast horizon and extends predictions to 15 days, generating forecasts in just 20 seconds using a single GPU. This advancement enables rapid 'what-if' scenario testing and probabilistic ensemble forecasts.
A study by University of Texas at Dallas bioengineers found that both cancerous and noncancerous colon tissue from young patients with colorectal cancer was mechanically stiffer than in older patients. This stiffness may promote the development of early-onset colorectal cancer, a condition rising over the past 30 years.
The Ecological Society of America has named 20 graduate students who will receive policy, communication and career training in Washington, D.C., followed by meetings with lawmakers on Capitol Hill.
Researchers developed antibody–drug conjugates that combine CD4 mimic and neutralizing antibodies to target HIV entry, showing seven times better efficacy than existing approaches. The strategy aims to block HIV before it enters the host cell, offering a more targeted therapeutic profile and potentially reducing adverse effects.
A new study uses AI to predict which ulcerative colitis patients with low-grade dysplasia are at high risk of developing colorectal cancer. The model integrates risk factors from narrative clinical notes, enabling more accurate and timely surveillance and potentially reducing treatment delays.
Researchers developed a new computational approach to predict chemotherapy response in triple-negative breast cancer, outperforming current methods. The TmS biomarker accurately sorts patients into those with favorable or poor prognosis, highlighting its potential as an effective starting point for patient stratification.
Researchers used satellite imagery and machine learning to estimate HDI scores for 61,530 municipalities and counties. The results show that over half the global population lives in areas with different development tiers than their national level, highlighting the need for finer-grained data to inform policy decisions.
The Brain Trauma Foundation has updated its guidelines for the care of patients with penetrating traumatic brain injury (pTBI) with new evidence-based recommendations and treatment algorithms. The guidelines aim to balance complexity with convenience for use during emergencies, providing practical flowcharts for clinicians.
The University of California San Diego School of Medicine and UC San Diego Health are now part of the NICHD Maternal-Fetal Care Network, expanding access to research on pregnancy and newborn health. Clinical trials will focus on maternal mortality, prematurity birth rates, and infant mortality rates.
60Nd, a UC3M spin-off, develops NeoMag to study tumor behavior, traumatic brain injuries, and wound healing processes. The technology enables researchers to replicate physical disease behaviors and identify new therapeutic targets.
Researchers found that ultrasounds performed too early during hospitalization were more likely to produce false positives, leading to additional invasive testing. Waiting until a fever resolved and closer to discharge did not prolong the hospital stay, but reduced unnecessary tests and added stress for families.
A systematic review found that musicians experience substantially higher rates of tinnitus, hearing loss, and hyperacusis compared to non-musicians. The study, which pooled data from 67 studies, revealed that 42.6% of musicians reported tinnitus, while 25.7% experienced hearing loss.
Research reveals that podocytes in aged rats adapt by increasing volume and forming atypical junctions to compensate for loss, while exporting unnecessary cellular components into the extracellular space. The study employed array tomography to elucidate age-related structural changes, shedding light on the mechanisms of aging glomeruli.
A new AI-powered algorithm, M-PACT, uses liquid biopsy to classify pediatric brain tumors based on DNA methylation patterns. The technology has been shown to achieve a high sensitivity rate of 92% in identifying brain tumors.
Researchers used mitochondrial DNA from 13 Jomon skeletons to examine population changes over time, finding a significant increase in eastern Japan between 13,000 and 8,000 years ago. This study suggests regional factors, such as climate and food resources, played a role in shaping the Jomon population history.
POST-PURPLE aims to convert urban wastewater and organic waste into valuable resources through innovative bio-based technologies. The project will demonstrate practical pathways toward cleaner, more circular urban biorefineries and reduce diffuse emissions.
A new study from Houston Methodist Research Institute finds that brain swelling during Alzheimer's treatment may indicate a stronger treatment response. Brain regions that swell have larger drops in brain plaques than areas that never swelled.
Researchers found that enhanced rock weathering can remove significant amounts of carbon from the atmosphere, with potential co-benefits for farmers. The method could remove up to 0.7-1.1 gigatons of carbon by 2100, depending on adoption rates.
A recent study at the University of Helsinki found that short periods of REM sleep impair horses' perseverance and performance in demanding learning tasks. Horses with longer REM sleep duration performed better in a reverse learning test, suggesting that REM sleep is associated with motivation and perseverance.
A psychology study found that social and emotional skills training benefits both younger and older adults equally. The study showed that participants in their twenties and those between 60-80 years old demonstrated similar improvements in emotional stability and extraversion after an eight-week personality intervention program.
A new study from Aarhus University finds that early puberty is associated with an increased risk of general psychological distress, psychiatric diagnoses, and the use of psychiatric medication. Girls who enter puberty early may have twice the risk of receiving psychiatric medication for mental health conditions compared to their peers.
A study found that forest conversion harm dung beetles by increasing temperatures and drying out the ground, making it hostile for them. The key species, Anoplotrupes stercorosus, is particularly affected, with its population declining as temperatures rise.
The JAX-NYSCF Collaborative and GSK are working together to develop human cellular models of neurodegenerative diseases. This collaboration aims to generate disease-relevant cellular models that can help scientists understand the underlying biology of neurodegenerative conditions like Alzheimer's disease.
Researchers analyzed downward climbing behaviors in 21 small-to-medium-sized arboreal mammal species to understand early primate evolution. They found primates used tail-first and side postures more often than non-primates, suggesting upright postures evolved to adapt to tree environments.
The collaboration aims to uncover actionable targets and biological pathways that may lead to personalized therapeutic options and improved outcomes for patients. Insilico's PandaOmics platform integrates clinical datasets with AI models to systematically prioritize druggable targets.
A Phase 2a trial of SPL026 demonstrated statistically significant and clinically meaningful reductions in depressive symptoms at two weeks, with effects lasting up to six months. The treatment was generally well-tolerated, and the findings provide clinical proof-of-concept for short-acting serotonergic modulation.
A new study by researchers from the University of Southern Denmark has found no evidence of naturally occurring DMT in the adult rat brain, even when its breakdown was inhibited. The study used highly sensitive methods to detect trace substances and examined whether administered DMT could be stored in serotonin neurons.
A new UCLA study found that adding immunotherapy to standard chemotherapy before surgery is safe and shows promise for some patients with borderline-resectable pancreatic cancer. The combination treatment helped patients live long enough to reach surgery, shrank tumors, and produced encouraging survival outcomes.
A new framework, BPR-LTC, integrates scientific research and bioethics into architectural planning for long-term care spaces. This approach aims to improve the health and well-being of residents by systematically incorporating evidence-based design principles.