Researchers at the University of Münster have found that using biomarkers to identify high-risk patients can significantly reduce the risk of kidney damage after major surgery. The approach has great potential to help sepsis patients too, and the team is working to incorporate these findings into international guidelines for the treatm...
A new study reveals that mitochondria in dry plant seeds are fully functional and contain the necessary proteins for cellular respiration. This allows seeds to germinate rapidly within minutes of water uptake, using stored carbohydrates, proteins, and fats for energy.
Researchers found five stages of silicic acid formation in fossilised wood, spanning 200 million years and documenting temperature, pressure, and composition conditions. The study uses quartz cathodoluminescence, fluid inclusions, and other techniques to reconstruct the geological history of the Saale Basin in central Germany.
Researchers at University of Münster and National and Kapodistrian University of Athens used cryo-electron microscopy to elucidate the structure of UapA transporter, a key fungal transporter. The study reveals a specialized 'elevator-type' transport mechanism that could lead to new antifungal drug strategies.
A team of researchers from the University of Münster and RIKEN research institute has discovered a previously unknown mechanism for salt tolerance in plants. They found that a particular chemical mark in the 'histone code' plays a crucial role in adapting to salt stress.
Researchers at University of Münster develop new light-driven reaction sequence, triggering sequential molecular transformations in a single vessel. The method enables efficient conversion of nitrogen-containing aromatic rings into complex three-dimensional molecular scaffolds.
Researchers found that a single parameter in the differential blood count can identify at-risk patients on hospital admission following a heart attack. Immature immune cells, specifically preneutrophils, significantly increase short-term risk of death.
Researchers have discovered that immune cells, specifically neutrophils, use neurotransmitters like dopamine and adrenaline to communicate in real-time. This finding has significant implications for understanding the regulation of the immune system.
Researchers discovered a previously unknown enzyme system in anaerobic bacteria that converts toxic chloromethane into non-toxic substances. The system, found in species Acetobacterium dehalogenans, has implications for environmental remediation and climate research.
A new study has discovered a crucial protein interaction that controls the photosynthetic machinery in plants. The discovery sheds light on how plants adapt to changes in light conditions and balance the light-harvesting capacities of both photosystems, enabling efficient energy transformation.
A recent study published in Nature Energy found that switching to a new battery technology does not automatically open the door to new market players due to established companies' structural advantages. The researchers analyzed over 15,000 patents and found significant knowledge transfer between lithium-ion and sodium-ion batteries.
Chemists at the University of Münster developed a new method to produce high-grade housane molecules, which are small tri- or quadripartite ring molecules crucial for drug development and materials science. The reaction is triggered by photocatalysis, enabling efficient access to valuable products.
Biologists have discovered that the talin protein is crucial for successful cell adhesion in animals, a mechanism likely developed from single-celled organisms. The study reveals the evolutionary conservation of this ancient adhesion mechanism, providing new insights into the origins of animal tissues and organs.
Researchers discovered that parasitic plants produce substances in their seeds that trigger the development of feeding organs, allowing them to attach to hosts quickly and effectively. This 'self-activation' mechanism enables parasites to infest hosts with high success rates, making them difficult to control.
A targeted treatment approach significantly reduces moderate and severe acute kidney injury after major surgery in high-risk patients identified by biomarkers. The study shows that a closely monitored set of clinical measures provides effective protection in the first hours after surgery.
A team of scientists simulated high-pressure conditions and found that onion-like layering in iron alloys can explain seismic anomalies in the Earth's inner core. This discovery suggests a compositional gradient with increasing core depth, linking anisotropy to chemical stratification.
A research team at the University of Münster has developed a new measurement method that combines fluorescence microscopy with MALDI mass spectrometry imaging, revealing metabolic differences in tumors. This allows for faster and more precise diagnoses and targeted therapies.
Researchers predict EU will need to meet 250 TWh annually for local battery cell production by 2050, offsetting 90 TWh of upstream fossil fuel energy. Maximizing recycling rates could reduce import dependency and future energy demand.
A team from the University of Münster has developed a method for recycling dry-processed lithium ion battery cathodes, separating materials and granulating them for reuse. The process is attractive not only for sustainability but also for cost efficiency.
A new study has identified a genetic biomarker that predicts which multiple sclerosis patients will respond well to treatment with glatiramer acetate. This allows for personalized therapy decisions to be made before starting treatment, with those carrying the HLA-A*03:01 gene variant showing significant clinical benefits.
A study by researchers at the University of Münster found that deploying end-of-life EV batteries as stationary energy storage devices can significantly reduce greenhouse gas emissions. By prioritizing reuse, countries with high renewable energies can save up to 56 million tons of carbon dioxide emissions.
Scientists have developed a new method for scanning tunnelling microscopy that enables the investigation of buried interfaces and atomic-scale structures. The technique allows for high-spatial resolution analysis of both surface and subsurface layers, revealing local magnetic properties and stacking sequences.
A research team from the University of Münster has developed a new way to produce spin waveguides, allowing for large networks capable of processing information efficiently. The team created the largest spin waveguide network to date, with precise control over properties such as wavelength and reflection.
A new international study provides deep insights into the genomes of superorganisms by analyzing the genetic basis of ant evolution. The researchers sequenced and compared the genomes of over 140 ant species, uncovering a series of evolutionary innovations that led to the emergence of distinct queen and worker castes.
Researchers have discovered that rocks from the Earth-facing side of the Moon contain a surprisingly high amount of chlorine, suggesting volcanic eruptions may be responsible for its distribution. This finding provides new clues about the Moon's origin and evolution, including the formation and chemical changes of its crust.
A study reveals an increasing polarisation between Asia and Western nations in future battery technologies, with Europe and the US focusing on improving existing lithium-ion batteries. Meanwhile, countries like China, Japan, and South Korea are investing in high-energy batteries and low-cost alternatives.
Researchers at the University of Münster developed a new strategy to swap carbon atoms with nitrogen atoms in pharmaceutical components, yielding biologically relevant compounds. The technique expands the synthetic toolbox for skeletal editing and offers new possibilities for drug design.
A recent study published in PLOS Biology found that behavioral experiments with insects exhibit a high level of non-reproducibility, with some results varying as much as 42%. Despite this, at least half of the findings could be successfully reproduced.
A research team has discovered that protein misfolding is a major cause of efficiency problems when using split inteins to produce proteins. By introducing specific mutations to the intein fragment, they were able to suppress aggregation and increase productivity.
The study reveals that the glycocalyx's main components are glycoproteins FMG1B and FMG1A, which regulate cilia adhesiveness without directly transmitting force for gliding motility. The findings expand knowledge of cellular regulation and protective mechanisms in other organisms.
A team of researchers has identified a calcium-activated bi-kinase module as the central molecular switch driving plant immune response. This discovery sheds light on how plants transmit immune signals from cell to cell without disrupting other signalling chains, using reactive oxygen species and calcium signals.
Scientists have developed genetically encoded biosensors to measure the ratio of NADPH to NADP⁺ in real-time, revealing new insights into cellular detoxification and protective function.
A study by the University of Münster's research team led by Prof Markus Lappe found that smooth eye movements cannot be performed for all types of visual motion, leading to a disruption of spatial perception. The researchers also discovered that the compensation mechanism for rapid eye movements is overridden when certain non-rigid mov...
Researchers at the University of Münster have developed a new method for synthesizing heteroatom-substituted 3D molecules, which are more stable than related flat rings. The innovative structures show promise as substitutes in drug molecules, offering new possibilities for drug development.
Researchers at the University of Münster deciphered the structure of α-latrotoxin, a potent neurotoxin that interferes with nervous system transmission. The toxin forms calcium-permeable membrane pores, inducing muscle contractions and spasms.
A new mathematical proof developed by Dr. Markus Tempelmayr and colleagues provides a method to solve certain classes of stochastic partial differential equations. This approach allows for the solution of complicated equations by combining solutions of simpler ones, offering a flexible tool for researchers.
Researchers have developed a synthesis method for introducing difluoromethyl groups into pyridines, a promising approach for new drugs and agrochemicals. The method allows precise introduction of the group at specific sites, overcoming a long-standing challenge in the chemistry field.
A team at the University of Münster developed an improved method for explaining machine predictions of chemical reactions, using mechanisms such as reproduction, mutation and selection. The algorithm creates customised molecular fingerprints that predict chemical reactions with surprising accuracy, suitable for predicting quantum chemi...
A German-Indian research team has achieved a significant breakthrough in developing miniaturized optical isolators by utilizing ultra-thin two-dimensional materials. The researchers successfully rotated the polarization of visible light by several degrees under small magnetic fields, paving the way for on-chip integration of optical co...
Chemists develop new reactions using model systems and substrates to demonstrate versatility. A new computer-aided method reduces subjective bias by analyzing real pharmaceutical compounds' complexity and structural properties. This improves data quality and facilitates machine learning applications.
Researchers have identified three distinct immunological endophenotypes of multiple sclerosis, defined by specific blood immune signatures. These findings could lead to more effective and tailored treatment strategies for patients with the disease.
A global survey of 45,000 individuals from 17 European countries reveals a collective downturn in psychological well-being after the Ukraine war, with vulnerable personalities struggling to recover. The study highlights the importance of mental health support, particularly for those already prone to stress.
A team from the University of Münster has detected biologically relevant nitrogen compounds and amino acids in an untreated English meteorite. The findings were made possible by a new type of detector design and high-resolution electron microscopy, offering insights into the origins of life on Earth.
A research team led by Dr. Ottaviano Rüsch from the University of Münster has discovered anomalous meter-sized rocks on the lunar surface covered in dust, exhibiting unique reflective properties. These findings provide insights into the processes that form and change the lunar crust, including potential magnetic anomalies.
Researchers at the University of Münster have developed a new method for converting carbon-nitrogen atom pairs in pyridines into carbon-carbon atom pairs through skeletal editing. This strategy has potential applications in the creation of new drugs and materials based on ring structures.
Researchers at the University of Münster found that DBT+SM detects invasive breast cancers more effectively than conventional DM, with a higher rate of early tumor stages. This approach may lead to improved screening effect and reduced breast cancer mortality.
A meta-analysis of 10,600 patients reveals that psychological interventions are highly effective in treating PTSD following multiple traumatic events. Trauma-focused cognitive behavioural therapy is the first line of treatment recommended in national guidelines, offering improved patient and therapist outcomes.
Researchers have developed a precise and efficient tool using 'single atom skeletal editing' to insert single carbon atoms into cyclic compounds, enabling ring size adjustment from five to six-membered rings. This approach opens up the way for designing and modifying complex molecular structures with potential industrial applications i...
A new AI-based method developed by IT specialists and physicians at the University of Münster can predict genetic features in leukaemia patients using high-resolution bone marrow images. The method extracts genetic aberrations from large datasets, enabling early diagnosis and targeted treatment without waiting for genetic analyses.
Researchers found that about one in a hundred infertile men with normal semen parameters have a loss of CatSper function, leading to failure of fertilization and medically assisted reproduction. The discovery enables evidence-based treatment and diagnosis of this channelopathy.