Researchers at ETH Zurich discovered a previously unrecognised mechanism for reduced fertility in polyploids, where twisted pollen tubes fail to reach the egg cells. The study found two genes controlling pollen tube growth, which are highly conserved and could be applied to plant breeding.
Scientists at Shandong University have created a novel approach to fabricate high-performance NiTiNb shape memory alloys using laser powder bed fusion. The in-situ alloying process yields good mechanical and functional properties, surpassing conventional casting methods. By integrating material synthesis and structure forming, research...
A research study investigates the role of TOR signalling in regulating seedling vigor, graft junction healing, and shoot-to-root communications. The study highlights the potential for improving grafting techniques and understanding plant communication to impact agricultural productivity and sustainability.
Scientists at Linköping University have created sheets of gold only a single atom layer thick, termed goldene. This material has given gold new properties that can make it suitable for applications such as carbon dioxide conversion, hydrogen production, and selective production of value-added chemicals.
A new AI-based model at Stanford Hospital predicts patient decline and flags physicians and nurses, enhancing communication and intervention. The study saw a significant improvement in clinical outcomes, with a 10.4% decrease in deterioration events among high-risk patients.
Small extracellular vesicles from young blood have been shown to dramatically extend lifespan, rejuvenate whole-body physiology, and reverse age-related degenerative changes in mice. The study demonstrates that these vesicles stimulate the expression of PGC-1 through their miRNA cargoes, ultimately improving mitochondrial functions.
Researchers at Van Andel Institute have identified a gene expression pattern, akin to a disease-related fingerprint, in brain cells with Lewy bodies. This finding sheds light on the molecular changes that occur in these cells, which are key pathological hallmarks of Parkinson's disease and some dementias.
A new study from Michigan State University suggests that political confidence can be a barrier to tolerating differing opinions, leading to discrimination and hostility. Those with high internal political efficacy are more likely to sever social ties and refuse conversations over political differences.
Despite rising temperatures in the region, Yellowstone Lake's ice cover has not changed over the past century, according to new research. Increased snowfall has acted as a buffer against warmer weather, delaying ice break-up and protecting the lake's unique ice phenology.
For the first time, scientists have created a system that interfaces two key components of quantum networks: quantum information creation and storage. The team used regular optical fibres to transmit quantum data, enabling long-distance communication and paving the way for distributed computing and secure communication.
Researchers have discovered a star orbiting a massive black hole 33 times heavier than the sun's mass, located 1500 light-years away from Earth. The binary system Gaia BH3 contains an ordinary star that seems to have formed over ten billion years ago.
Qualitative research finds that locum doctors face significant patient safety challenges due to unfamiliar work environments, lack of support, and inadequate governance arrangements. The study calls on NHS leaders to rethink their approaches to engaging and supporting locums, and for locums themselves to reflect on their experiences.
A systematic review found a lack of reporting on ethnicity and underrepresentation of ethnic minority groups in MLTC intervention studies. Ethnic minorities are more likely to experience higher levels of socioeconomic deprivation, which contributes to the development of MLTCs.
Researchers discovered a crucial amino acid exchange that enables PsiM to carry out double methylation during evolution. The enzyme plays a key role in psilocybin production, with implications for biotechnological production of the active ingredient.
A new study suggests that ammonia could be a smart and energy-efficient fuel in the race to achieve net zero in shipping. The NTNU researchers' model shows that IMO's ambitions have a strong impact on shipowners' choice of propulsion systems.
Researchers found that schools' perception of girls as more emotionally open leads to them being prioritized for mental health support, while boys are often overlooked due to disruptive behaviors. This creates a new form of gender inequality, where both genders remain 'trapped' in unhelpful stereotypes.
Scientists at Princeton Plasma Physics Laboratory successfully simulate a novel combination method for managing fusion plasma. By combining electron cyclotron current drive (ECCD) and resonant magnetic perturbations (RMP), researchers can create a more stable plasma edge, reducing the amount of current required to generate RMPs.
Researchers developed novel therapeutic bispecific antibodies targeting IgM and B-cell surface antigens, which directly inhibited cell proliferation via cell-cycle arrest and apoptosis in vitro. These findings suggest that anti-IgM/B-cell surface antigen-binding specific antibodies are promising therapeutic agents for B-cell malignancies.
The new Lancet Commission on Breast Cancer warns that people with metastatic breast cancer have been often forgotten, highlighting key barriers and inequities in healthcare. The report advocates for six crucial areas for change, including improving early diagnosis programs and communication with patients.
Scientists discovered a 201-million-year-old fossilized plant that exhibited net-like veining, similar to modern flowering plants. The ancient plant, Furcula granulifer, is part of an extinct group of seed ferns that failed to evolve efficient leaves.
A new testing protocol combining clinical history with multiple home stool tests could significantly speed up diagnosis of inflammatory bowel disease (IBD) by reducing the need for unnecessary colonoscopies. Serial faecal calprotectin tests were found to strongly predict possible IBD, Crohn's Disease, and Ulcerative Colitis.
Scientists at Sanford Burnham Prebys have identified promising links between common HIV drugs and a reduced incidence of Alzheimer's disease. The study analyzed over 225,000 medical records and found that RT inhibitor exposure was associated with a statistically significant reduced incidence and prevalence of AD.
A new study published in Royal Society Open Science found that shared ancestry and transformative experiences can strengthen psychological bonding with humanity at large, motivating prosocial action on a global scale. The research suggests that fostering a shared global identity could facilitate cooperation on the global level.
Researchers at the University of Pittsburgh have discovered how to overcome resistance to conventional immunotherapies in metastatic uveal melanoma. They developed a clinical tool called Uveal Melanoma Immunogenic Score (UMIS) to predict patient response and improve treatment outcomes.
A three-year research project at the University of Oldenburg examines the resettlement history of Hazor, a Bronze Age megacity in eastern Mediterranean, and its impact on early Israelite identities. The team aims to uncover how narratives about these events influenced the shaping of early Israelite cultures.
Researchers develop novel method to prepare carbonized polymer nanodots emitting multi-color ultra-long Room-temperature phosphorescence from blue to green. The resulting materials exhibit high quantum yield and resistance to photobleaching, holding great promise for security and data protection applications.
Researchers found that ~60% of tissues exhibit a significant negative correlation between age and stemness score, indicating a pan-tissue decline in stemness. This study adds weight to the idea that stem cell deterioration contributes to human aging, with hematopoietic stem cells from older individuals showing higher stemness scores.
Researchers have identified 59 benzylisoquinoline alkaloids in lotus, showing significant pharmacological potential in treating life-threatening diseases. The study highlights the importance of understanding biosynthetic pathways and structural modifications to develop effective clinical drugs.
The study found that chronic administration of melatonin prevents obesity and reduces visceral obesity by around 3%. Melatonin also enhances weight loss when combined with cold water bathing. The researchers recommend incorporating melatonin, natural light exposure, and physical activity into daily routines to manage obesity.
Researchers developed a technology to detect infectious disease viruses in real-time using a single nano-spectroscopic sensor. The system uses molecular fingerprinting and can detect specific substances with tailored detection, enabling rapid and precise analysis.
Scientists at CNIC have identified mechanisms by which anthracyclines damage the hearts of cancer patients, leading to cardiac injury. The study suggests that a protein-enriched diet may prevent muscle atrophy caused by anthracycline chemotherapy.
A new study finds that elite coaches are migrating to Western countries due to dual imbalances between sending and receiving nations. Researchers interviewed Korean coaches who sought better coaching environments with more modernisation and athlete welfare.
A new study found that nasal cells from children respond quickly to SARS-CoV-2 by increasing interferon, restricting viral replication. In contrast, nasal cells from elderly individuals produce more infectious virus particles and experience increased cell shedding and damage.
A new study in the Global Strategy Journal shows that corporate misconduct, such as corruption and discrimination, can negatively impact foreign subsidiary performance. The research monitored 335 subsidiaries in 109 countries over nine years, finding that social irresponsibility hurts sales regardless of where the incident occurred.
A new USC-led study on rats that fed a high-fat, sugary diet during adolescence found impaired memory and disrupted acetylcholine levels. The researchers suggest that a junk food-filled diet in teens may disrupt their brains' memory ability for a long time.
A comprehensive atlas of ageing human muscle reveals genetic and cellular processes behind muscle deterioration, including new cell populations that may explain age-related differences. The study also identifies compensatory mechanisms to counteract ageing, offering avenues for future therapies.
Researchers at Bar-Ilan University developed a new AI confidence measure that distinguishes between high- and low-confidence decision making in deep learning architectures. This breakthrough enables the creation of safer and more reliable autonomous vehicles by prioritizing human intervention when confidence levels are lower.
Cyanobacteria have been found to manipulate microorganisms to promote their own photosynthesis by regulating nitrogen and carbohydrate metabolism. This newly discovered gene, NirP1, plays a key role in this process, allowing cyanobacteria to export nitrite that stimulates the growth of beneficial microorganisms.
Scientists have developed a novel maleic acid-treated bacterial cellulose gel that significantly improves bone repair outcomes. The gel's enhanced biocompatibility and osteogenic gene expression promote cell proliferation and differentiation, paving the way for potential applications in tissue engineering.
Researchers develop AI-assisted algorithm to analyze surgical videos of cataract surgeries in Global South, aiming to improve surgical outcomes and training. The algorithm can work with conventional image material and smartphone videos, addressing the need for resource-saving solutions in these countries.
Scientists create a small drum that stores data sent with light in its sonic vibrations, allowing for secure transmission over long distances. This innovation has the potential to revolutionize quantum computing and enable an internet with quantum speed and security.
Researchers used thermodynamics to describe the expansion of the Universe, finding that adiabatic and anisotropic effects are accompanied by cooling due to the barocaloric effect. The study proposes a novel way to investigate anisotropic effects associated with the expansion of the Universe.
Hyperemesis gravidarum can significantly impact maternal health and infant well-being, leading to weight loss and dehydration. Treatment involves relieving symptoms with antiemetics and other medications, while remedies like ginger products may provide some relief.
A University of Washington study found that anti-Christian bias claims can be used to signal allyship with white Christian Americans, perpetuating implicit racialization. White Christians perceive politicians concerned about anti-Christian bias as more willing to fight for white people and less offensive than those concerned about anti...
Researchers at Graz University of Technology discovered three side-channel attacks on WebGPU browser interface, allowing them to access a computer's cache memory and extract sensitive information. The attacks were fast enough to succeed during normal surfing behavior, highlighting the need for browsers to address GPU security and priva...
Research by UniSA economists explores how small businesses in South Australia's Kangaroo Island and Barossa Valley regions adapted to disaster recovery, highlighting the importance of financial stability, online presence, and community support. The study found that a 'dynamic capabilities approach' is key to long-term recovery, and reg...
Scientists from Osaka University create borane molecules that exhibit red-shifted light emission upon binding to fluoride, enabling versatile materials for electronic display and chemical sensing applications. The researchers also achieve fine-tuning of the color of light emission by adjusting the quantity of added fluoride.
A team of scientists has created a single-cell atlas for the highly regenerative worm Pristina leidyi, revealing new insights into its regenerative abilities. The study characterizes all major annelid cell types and provides molecular signatures that could inform stem cell technologies and regenerative medicine.
The Yangtze River Basin faces severe water quality issues due to excessive fertilizer and pesticide use, as well as the inappropriate disposal of agricultural waste. The study highlights the need for balancing green agriculture with development to ensure food security and water quality.
Researchers identified a novel mechanism where APP-CTFs disrupt organellar communication, interfering with cellular homeostasis and leading to endolysosomal dysfunction. This finding suggests that preventing APP-CTF accumulation could be crucial for developing new AD treatments.
A study by researchers at Washington University School of Medicine has found that a drug used to treat epilepsy can prevent brain tumor formation and growth in mice with neurofibromatosis type 1 (NF1). The drug, lamotrigine, was shown to be effective at lower doses than those used for epilepsy, and its effects were lasting. The finding...
Research finds Parkinson's disease alters bodily sensations associated with basic emotions, shifting focus from chest to abdominal area. The study highlights the significance of non-motor symptoms in Parkinson's disease, raising new perspectives for treatment and research.
Researchers have discovered a greener way to produce ammonia, essential for fertilizers, by developing a new catalyst that works stably at relatively low temperatures. This breakthrough reduces the amount of energy needed to synthesize ammonia, making it an attractive alternative to fossil fuels.
A new vaccine, RQ3027, has been found to elicit superior neutralizing antibodies against several emerging SARS-CoV-2 variants. The study also showed that the vaccine was well-tolerated with no serious adverse reactions identified.
Researchers from the Institute for Basic Science created QLEDs using a ternary nanocomposite film that enhances carrier delivery to quantum dots, resulting in optimal device performance. The devices exhibit high brightness and low threshold voltage, with no damage when stretched up to 1.5 times.
Researchers investigated the role of microRNAs in regulating cardiomyocyte injury after coronary microembolization. They found that changes in miRNA levels decrease myocardial autophagy and worsen cardiac prognosis. This study suggests a potential strategic pathway for therapeutic intervention in CME management.
Contraceptive services experienced downward trends from an initial increase in the month after Dobbs v. Jackson, indicating growing challenges for access. The study found decreasing workforce numbers providing contraception methods.
A study of 898 patients with atrial fibrillation found that immediate recurrence during the blanking period after radiofrequency catheter ablation correlates with greater costs, hospitalization duration, and elevated 1-year cumulative AF recurrence rate. IEC was identified as an independent predictor of Im-Recurr.
A new study uses GEDI LiDAR to accurately map tree height composition in forests, revealing nuanced details of forest structures and their implications for biodiversity and carbon sequestration. This breakthrough technology offers a fresh perspective on forest ecosystems, enhancing ecological research and forest management.
A recent study by University of Hawaii at Manoa researchers highlights the hidden threat of global underground infrastructure vulnerability to sea-level rise. Shallow and saltier groundwater exacerbates corrosion and failure of critical systems such as sewer lines, roadways, and building foundations in cities worldwide.