A new study reveals that CDK8 helps plants allocate sulfur for growth and defense by regulating the use of sulfur in molecular machinery. Plants can switch between high-sulfur and low-sulfur defense strategies, conserving sulfur when necessary, to maintain immunity.
Researchers developed a programmable virtual metasurface that converts invisible infrared images into visible light while dynamically controlling focus. The system uses software-defined optical patterns and can be reconfigured in real time, offering a new approach for infrared imaging and wavefront control.
Researchers investigated potential locations for small-scale ammonia plants using electrolysis, which could reduce emissions and dependence on global supply chains. Hybrid plants combining local renewable energy with grid electricity perform best, offering a more economical solution.
Researchers identified a key driver of liver fibrosis progression: FSP1+ macrophages that activate PGK1 through lactylation. This self-reinforcing loop amplifies glycolytic signaling, promoting liver fibrosis. A cell penetrating peptide targeting PGK1 lactylation blocks fibrosis progression in preclinical models.
Researchers found that aged mice brains show increased micronuclei, which microglia internalize, leading to changes in morphology and gene expression. This process may contribute to age-associated inflammation and vascular dysfunction.
Researchers discovered branched O-mannose glycans play a crucial role in maintaining nodes of Ranvier and efficient nerve signaling. The study found that these sugar structures help preserve the narrow architecture required for fast and reliable communication.
Researchers developed a new class of optical storage technology that combines phase-change materials with responsive hydrogels for full-color image multiplexing. The device offers robust rewritability and can be controlled using environmental conditions, enabling user-friendly and secure data encryption.
A new study in Nature Communications reveals a hidden source of antibiotic resistance in Australian soil. The mcr-12 gene was found in contaminated freshwater sediment and provides bacteria with resistance to polymyxin, a critical last line antibiotic.
Researchers have identified a protein called vitronectin that triggers the scarring in lungs leading to idiopathic pulmonary fibrosis. This discovery opens up a new potential treatment pathway using the vitronectin-macrophage pathway to inhibit scar tissue growth.
Researchers presented a comprehensive system-level review of polymer-based flexible wireless sensors for seamless skin-like mechanical compliance with real-time health monitoring. The review breaks siloed tradition by addressing sensing mechanisms, wireless systems, manufacturing strategies, materials, and clinical applications.
Researchers from Tianjin University and Lund University developed a pioneering in-cylinder active reduction strategy to combat high NOx emissions from ammonia-fueled internal combustion engines. The study successfully reduced NOx emissions by 14.4% using an ammonia post-injection technique.
Researchers have developed a novel hierarchical hydrogel electrolyte that balances mechanical robustness and ionic conductivity, enabling ultralong-life flexible zinc-ion batteries with impressive performance. The bioinspired design achieves exceptional ionic conductivity and accelerates Zn2+ desolvation kinetics.
Researchers unveil high-performance, earth-abundant Fe-N-C catalysts using AI and quantum chemistry. The 'dual modulation' strategy accelerates oxygen reduction reaction in fuel cells, enabling cheaper and more efficient hydrogen fuel cells.
UCSF Health Converge accelerates development of AI tools for real-world care delivery by co-developing solutions with select companies. The program focuses on building patient-centered, clinically effective AI solutions that align with UCSF Health's standards.
SFU's significant reduction in greenhouse gas emissions is a result of decades of strategic energy management, infrastructure investment, and collaboration with external partners. The university's progress builds upon its commitment to resilience and sustainability, values reflected in its 'What's Next: The SFU Strategy'.
Sylvester researchers develop AI-powered fracture prediction models, train as wildland firefighters to reduce cancer risk, and discover new targets for pancreatic cancer treatment. A new tumor-on-a-chip model shows how pancreatic cancer hijacks immune cells.
A Mayo Clinic-led study found that continuing maintenance therapy beyond two years did not improve overall survival for patients with standard-risk multiple myeloma. The findings suggest that treatment duration can be safely tailored, reducing treatment burden and costs.
A team of researchers from Saitama University has discovered a natural peptide aptamer called Calmodulin-binding peptide (CBP) that can selectively recognize two structurally distinct proteins, calmodulin and human midkine. CBP binds to calmodulin in the presence of calcium ions and to human midkine in the presence of sodium ions.
A research team used a simple physical model to connect sublattice melting with cooperative and spatially heterogeneous ion transport, revealing a fundamental mechanism behind superionic conduction. The findings offer a unified explanation for this phenomenon, which could guide the design of next-generation solid-state batteries.
A new study from UT Health San Antonio found a link between long sleep hours and higher levels of an Alzheimer's-related protein in the blood. The research suggests that long sleep may reflect early neurodegenerative processes, but more sleep is not always better for brain health.
Researchers argue that social media restrictions should be viewed as part of a complex system rather than isolated policies. They suggest using systems mapping to anticipate effects and design more balanced approaches, considering factors such as school engagement, social connections, and industry responses.
A systematic review and meta-analysis found that weight loss drugs can reduce key symptoms of binge eating disorder, including binge eating episodes, loss-of-control eating, and emotional eating. The study suggests that these medications could be an important part of treatment plans for people with binge eating disorder.
A study found that Black African and Caribbean women in the UK are less likely to attend breast cancer screening due to limited knowledge and trust issues with healthcare providers. Researchers recommend stronger links between GP practices, breast screening services, and community champions to improve awareness and attendance.
KAIST develops robot that can autonomously choose gait strategy for its surroundings, switching between walking, running, jumping, and other locomotion skills. The team generated 15.5 hours of training data using computer simulations alone, enabling the robot to move quickly and stably in real outdoor environments.
Researchers analyzed data from over 500,000 births in Scotland to examine the effects of epidural analgesia on newborn health. The study found no association between epidural use and serious neurological conditions, sepsis, or cerebral palsy in childhood.
Data shows Black doctors are up to 30 times less likely to be offered medical training posts, with some specialties seeing a gap of over 100-to-1, while Asian applicants face similar challenges. The findings highlight ongoing barriers faced by ethnic minorities in the UK health service.
Researchers developed an analytical technique to evaluate culture media quality by analyzing patterns of fluorescence from synthetic polymer probes. This technology detects quality differences in serum, stem cell, and microbial cultures with high precision, improving reproducibility.
Researchers are engineering biochar-based composites to overcome limitations, such as insufficient adsorption capacity and limited selectivity for certain emerging pollutants. The new review highlights the importance of balancing treatment performance with environmental safety throughout the material's life cycle.
A condition affecting 170 million adolescents and women worldwide is being redefined to capture its complexity, including its far-reaching health impacts on metabolism, mental health, and reproductive systems. The proposed name change aims to improve awareness among patients and providers, encouraging more comprehensive care.
A new study uses machine learning to predict chemical toxicity in rare and endangered species, reducing the need for direct biological testing. The model achieved strong performance predicting acute and chronic toxicity, with life stage being a key factor.
A new study reveals that carefully designed power cycles can convert more of LNG's overlooked resource into useful electricity. Researchers found that a two-stage Rankine cycle with reheating produces the most effective design, generating up to 9.2 megawatts of net power.
The ECOG-ACRIN ENDURANCE trial found that indefinite lenalidomide maintenance had no survival benefit and more toxicity compared to stopping treatment after 2 years in patients not undergoing a stem cell transplant. The study suggests that fixed duration treatment can significantly reduce healthcare costs.
Researchers at Texas A&M University have found a way to intervene early in traumatic brain injuries using a natural, gut-derived chemical that prevents post-traumatic epilepsy from taking root. The treatment reduced brain inflammation, improved memory and mood, protected brain cells, made seizures both rarer and harder to trigger.
Scientists harness non-Abelian anyons to perform any operation a quantum computer needs, eliminating the need for expensive magic state distillation. The approach enables fault-tolerant computations and has potential applications in quantum error correction and basic physics research.
A new study from the University of Washington highlights the potential consequences of losing roadless protections on rivers and drinking water supply. The study found that over 80,000 miles of rivers receive some protection from the rule, reaching 25 million people across the country.
Scientists at MD Anderson Cancer Center have identified a previously unknown mechanism by which T cells attack and eliminate acute myeloid leukemia (AML) cells. The discovery reveals that AML cells use a CD64-dependent pathway to evade traditional MHC recognition, potentially explaining why AML is sensitive to immune-based treatments.
A recent study published in Neurology found that Black individuals born outside the US have a significantly lower risk of stroke compared to those born in the US. The study, which analyzed data from over 64,000 adults, also found that immigrants who arrived within 15 years of the survey had a 73% lower odds of stroke.
A study reveals that forests and rivers work together to strengthen amphibian microbiomes and protect them from a deadly fungus. The research found that disconnected habitats impair the ability to recruit defensive microbes.
A pair of studies by NYU psychology researchers found that teaching leadership is not an innate trait and encouraging diverse mental representations of successful leaders can significantly increase teens' sense of belonging in leadership roles. By changing young people's views on leadership, the research suggests strengthening ambition...
A study found that college students who spent more time online and experienced online harassment were more likely to report suicidal thoughts. Cisgender men showed the strongest link between time spent online and suicidal thoughts, while online harassment was linked to higher risk across all gender groups.
The Perseverance rover has discovered evidence of repeated asteroid impacts creating a 3.9-billion-year-old 'weather report' from early Mars, preserving a record of variable-sized impacts and potential interaction with water or ice. The findings offer insights into one of the most turbulent chapters in the solar system's history.
A new study finds that most Americans view illicit drugs as a serious national problem, but perceive little progress in addressing it. Perceived progress on drug policy is strongly linked to political affiliation, with Republicans and Democrats having starkly different views.
A rare case report highlights the challenges of diagnosing cervical angioleiomyoma, a benign tumor presenting symptoms similar to those of common gynecological conditions. The study describes a successful surgical excision and excellent clinical outcome for a young woman with persistent heavy menstrual bleeding and pelvic pain.
New research reveals altitude-dependent carbon storage mechanisms in diverse forest ecosystems. High-altitude conifer forests excel at storing carbon in biomass, while lower-elevation mixed broadleaf forests stabilize soil carbon. Effective forest management requires altitude-specific approaches to conserve biomass and enhance soil org...
Canadian agri-food leaders recommend strengthening food infrastructure, improving preparedness, and building resilience to protect against geopolitical threats, biological threats, trade disruptions, and supply chain vulnerabilities. The report outlines seven key recommendations to ensure Canada's long-term food resilience.
Researchers at St. Jude Children's Research Hospital discovered that smaller sub-compartments within the nucleolus form to finish the final steps of ribosome assembly. These sub-compartments lock major ribosome building blocks together until they are assembled, preventing a key protein from associating with them prematurely.
A new award will help advance the proof-of-concept work toward commercialization of an at-home HIV test that detects cases not caught by lab tests. The device, called Click Chemistry Amplified Nanopore (CAN) sensing, has shown promising results in early studies.
The University of Minnesota Medical School research team has received a $10 million NIH grant to study how animals fight infection. The team will utilize a 'cellular zoo' of living cells from over 100 animal species to understand how different species recognize and respond to viral infections.
Scientists have found a way for the circadian clock to produce a winter version, which can suppress reproduction and alter activity patterns in fruit flies. This discovery could lead to new ways to disrupt pest populations and improve human health by better understanding seasonal influences.
The 24hreview initiative presents a standardized, shared pre-submission integrity layer for the global academic publishing community. The platform has already piloted its approach with Wiley and seen reliable verification of manuscript integrity within 24 hours.
Scientists have unveiled a new structure of the kinesin-1 protein, showing how cells control its on-off switch. The discovery could shed light on incurable neurodegenerative diseases such as ALS and Charcot-Marie-Tooth Disease Type 2.
Researchers developed a hybrid technology combining human learning and machine learning in noninvasive BCIs, producing rapid and sustained gains in motor imagery control. The study demonstrates significant scientific and technological advancement in BCIs, establishing a scalable pathway toward robust neural interfaces.
A new species of colobus monkey, 'Likweli', has been identified by its distinctive facial markings and unique call. The rare species is found in the dense forests of Lomami National Park and is considered Endangered due to its small geographic range and population size.
A previously unknown species of African monkey, Colobus congoensis, has been identified in the Democratic Republic of Congo. The species, known locally as Likweli, features a distinctive orange face patch and is one of the rarest discoveries in modern primatology.
Scientists have discovered that marsupial forelimbs rapidly develop over a four-day period, challenging current understanding of limb development in vertebrates. This finding highlights the unique biology of marsupials and has important implications for conservation efforts.
Researchers developed a new way to uncover differences in how viruses infect and destroy individual microbial cells. The study used a mathematical modeling framework to analyze infection outcomes in individual cells, revealing striking accuracy and new insights into viral behavior.
Researchers have developed a new drug candidate, SB-0110, that boosts L-dopa's benefits while reducing dyskinetic side effects in animal models of Parkinson’s disease. The compound preserves the gene-activity patterns tied to L-dopa’s benefits while counteracting biological changes associated with dyskinesia.
A study published in PLOS Climate found that teleworking can reduce carbon emissions from commuting, but this benefit may be offset by increased utility use at home. More frequent and separate home office users produced higher emissions due to work-related housing and technology use.
Researchers found that providing honeybees with prebiotics and probiotics helped them survive thermal stress. The study suggests these nutritional supplements can buffer the survival of bees and improve antioxidant enzyme activity.
A groundbreaking study published in Science Translational Medicine has successfully restored the sense of touch in individuals with spinal cord injuries using brain-computer interface technology. The study found that electrical pulses delivered to the somatosensory cortex remained stable and localized over a period of up to 10 years, w...
Researchers from the University of Tokyo used limpet shell analysis to reconstruct the journeys of tiny creatures between hydrothermal vents, finding they explore sunlit upper ocean during larval stage. This discovery helps explain how animals living at isolated vent sites can spread over hundreds or thousands of kilometers.
A New Jersey meteorite contains high concentrations of salt and briny fluids that can create molecules vital for life on Earth. The discovery sheds light on the chemical origins of life on our planet.
The Trump administration's 2025 repeal of the US Roadless Rule could put 25 million Americans at risk due to loss of access to pristine watersheds. The study assesses the value of this rule for both human health and nature.
Researchers reconstructed past methane concentrations using clumped isotopes in air from the past, revealing significant changes since industrialization began. The study suggests human activities are disrupting the balance between methane emissions and breakdown, driving rising atmospheric methane concentrations.
Researchers have developed ultrathin, invisible on-skin electrodes that can measure biological signals without altering appearance or social interactions. These new sensors achieve this by closely matching the appearance and texture of natural skin, reducing reflections and eliminating visibility.
A study analyzing county-level data reveals broad geographic patterns and local factors influencing breastfeeding initiation in the US. Localized approaches addressing disparities in breastfeeding initiation are necessary to complement national policy efforts.
SourcePLOS·JournalPLOS Global Public Health·TypeObservational study·DateJul 15, 2026
A German analysis explores how COVID-19 disrupted typical transmission patterns of respiratory diseases, leading to shifts in their seasonal surges. The study found that population-level loss of immunity after the pandemic caused a buildup of susceptible hosts, resulting in earlier peak weeks for these surges.
SourcePLOS·JournalPLOS Global Public Health·TypeObservational study·DateJul 15, 2026
Researchers confirm discovery of new African monkey species Colobus congoensis, previously unknown in over 75 years. The species is distinct from other African colobus monkeys with unique cranial, dental, and skeletal characteristics.
A study in PLOS One identified T. rex as the likely cause of some tooth marks on fossils from Cretaceous-era Wyoming, providing insights into animal behavior and ecosystem dynamics. The researchers developed a guide to interpret tooth traces on fossils, distinguishing between natural and bite-related marks.
A study analyzing 30,527 English dementia patients found hospital readmissions associated with multiple factors including sex, health conditions and post-discharge care. The research highlights the importance of monitoring and managing these risk factors to prevent hospital readmissions.
Researchers found that horses' heart rates increased when viewing wolves, regardless of behavior, while keeping a poker face and not displaying overt behaviors. The study's findings have implications for horse welfare and rider safety, as horses may be experiencing internal agitation without physical signs.
A new analysis of over 110,000 papers submitted to Science and Science Advances reveals Western scientists, larger teams, and top-ranked universities have slight advantages in acceptance rates. The study provides insights into editorial dynamics and outcome disparities, shedding light on the peer review process.
A new study from Griffith University reveals how different cave environments leave distinct 'fingerprints' on skeletal remains, providing a powerful tool for reconstructing past environments and histories in challenging conditions. Bones preserved in underwater caves often preserve their structure and surfaces remarkably well, while un...
A University of Colorado Boulder-led study analyzed over 110,000 manuscript submissions to top-tier scientific journals, revealing that prestige, topic, and location matter most in determining publication. The study found a significant disadvantage for authors based in China and those studying social sciences.
Researchers analyzed isotope data from over 100 individuals to find that some societies relied heavily on maize grown within diversified agricultural systems. These communities developed resilient polycultural food-production systems combining domesticated crops with wild plants and local ecological knowledge.
Researchers have found four exoplanets orbiting Barnard's Star, all smaller than Earth and Venus, but larger than Mars. The planets' composition suggests they are rich in magnesium, which creates periclase, a mineral that does not store water effectively.
A new study from the University of Michigan highlights the limitations of framing loneliness as a solely medical issue. Chronic loneliness and social isolation are linked to higher risks of disease, death, and economic costs, but experts argue that healthcare alone cannot rebuild social ties or address underlying social issues.
Researchers at MIT have created a precise way to engineer artificial blood vessels by mechanically stretching and pulling a "blood vessel on a chip". The new method, reported in the Proceedings of the National Academy of Sciences, enables controlled sprouting of new vessels and programming of their growth patterns.
Researchers have identified a new fungal species, Semicentenialea rex, representing a new class of fungi called Semicentenialomycetes. The fungus was isolated from roots in Sweden and has unique characteristics that set it apart from other rust fungi.
Dr. Rui Yang receives a Burroughs Wellcome Fund Career Award for Medical Scientists to uncover genetic causes of life-threatening immune disorders and identify new treatment paths. The research aims to advance diagnosis and understanding of rare diseases while fostering the next generation of scientists.
Researchers at Texas A&M University designed a fictional hospital to demonstrate the business case for investing in better design. The model shows that by incorporating evidence-based design strategies, hospitals can recover their additional construction costs within two years and achieve over $100 million in net financial gains over t...
A Johns Hopkins Medicine team created a computational model to forecast which patients with hepatocellular carcinoma (HCC) will benefit from combination treatment using immunotherapy and targeted therapy. The spatial QSP modeling platform accurately predicted response rates for virtual patients, demonstrating its potential to inform pe...
Reducing carbon dioxide concentration improves microbial production of biodegradable plastic, such as poly[(R)-3-hydroxybutyrate]. Lower CO2 levels trigger adaptive cellular responses that enhance carbon utilization efficiency.
The Brain & Behavior Research Foundation recognizes six early-career scientists for their outstanding contributions to mental health research, including Dr. Joline Fan's work on brain circuitry and personalized neuromodulation therapies, and Dr. Nili Solomonov's development of scalable neuroscience-informed psychotherapies for depression.
Researchers discovered that reducing microglial activity worsened abnormal electrical activity and increased seizure-like events in a mouse model of Alzheimer's disease. Microglia are not just drivers of inflammation but also perform important housekeeping functions to maintain healthy brain activity.
Researchers created a tool that leverages large language models to build novel languages with unique grammatical structures and vocabularies. The ConlangCrafter tool generates diverse languages, which can be used for creative applications such as video games and movies, or aid researchers in studying poorly documented languages.
Research from the University of Reading shows that cutting air pollution globally can strengthen the Indian monsoon, increasing rainfall by 0.28 millimetres a day across the country. The study found that regional action alone can have the opposite effect, reducing rainfall in parts of India.
Researchers have developed a systematic cross-calibration method for GPS satellite data, producing a long-term dataset that spans two full solar cycles. The calibrated dataset provides a reliable resource for studying relativistic electrons in medium Earth orbit, enabling more accurate predictions of electron flux enhancements.
A University of Stirling study found that most people in the UK don't fully understand dog laws and often believe stronger protections exist than actually do. Dog owners were consistently more confident but not more accurate in their knowledge, raising concerns about improving legal understanding.
A team of researchers from the University of Münster and RIKEN research institute has discovered a previously unknown mechanism for salt tolerance in plants. They found that a particular chemical mark in the 'histone code' plays a crucial role in adapting to salt stress.
Researchers developed a new computational approach to identify genes that characterize different cellular states from mRNA-seq data, offering more accurate and interpretable analysis of complex biological data. The Cartesian Distance-Based Gene Expression (CDBGE) algorithm was evaluated using multiple publicly available datasets, demon...
Researchers at Shaanxi Normal University have developed a novel titanium-chromium nitride catalyst that efficiently traps and rapidly converts polysulfides, key to improving Li-S battery efficiency. The new material demonstrates exceptional stability and effectiveness in suppressing the shuttle effect and enhancing conversion efficiency.
Researchers at ISTA discover how to turn single molecules into effective magnets, overcoming weak magnetic field limitations. The findings could lead to breakthroughs in nanoelectronics and the design of single-molecule nanodevices.
The Monell Chemical Senses Center has signed a 20-year lease to relocate and expand its operations to One uCity Square. The new facility will provide world-class support for sensory science discovery and strengthen Philadelphia's life sciences ecosystem.
Researchers developed DeepHHF, an AI model that identifies patients at high risk of heart failure up to five years in advance. The model analyzes standard ECG recordings and detects subtle abnormalities that are often imperceptible to the human eye.
The study identified specific climate measures for each city type, including infrastructure investment in heat protection, urban greening, and transport transition. Rapidly growing cities like Tirana and shrinking cities like Daugavpils benefit from nature-based solutions and infrastructure upgrades.
A new study found that students and staff involved with collegiate recovery programs held varying definitions of harm reduction, which shaped their perspectives on integrating it into CRPs. The study suggests opportunities to reframe harm reduction in a way that builds common ground and meets students' diverse recovery needs.
Researchers developed a new molecular strategy to control the critical interface in perovskite solar cells, resulting in a power conversion efficiency of 26.19%. The approach reduced interfacial disorder and nonradiative voltage losses while improving charge carrier transport.
A novel measurement cell enables in-situ/operando X-ray absorption spectroscopy measurements under high pressures and temperatures, providing new insights into thermocatalytic processes such as the Fischer-Tropsch synthesis. The setup is suitable for investigating catalytic gas-solid reactions under realistic operating conditions.
A USF study has identified South Florida as a crucial feeding ground for Atlantic tarpon, highlighting the importance of the region to the species' migrations. The research found that tarpon rely on distinct 'foraging landscapes' and can travel hundreds of kilometers to find food.
Researchers at Tsinghua University Press have created MXene-PVDF textiles that offer enhanced thermoregulation for adaptive personal protection, while also providing safe Joule heating. These materials are promising for wearable personal protection in extreme temperatures, enabling workers to operate safely and efficiently.
A specific subgroup of neutrophils signals the immune system to dial down its response, allowing regeneration. The study shows that the fine regulation of inflammation is crucial for healing and that unleashing the right signals can reactivate nerve regeneration.
A new study published in Environmental Research Letters found that climate mitigation and adaptation strategies often lack real-world data, hindering effective climate policy. Researchers identified the need for systematic collection of observational data across cities to determine what truly works, under which conditions, and for whom.
Researchers explored how AI and metabolic modeling can inform effective biocontrol strategies to combat antimicrobial resistance in built environments. Microbial biocontrol using 'good' microbes has shown promise, but inconsistent outcomes are due to various factors, including genetic differences and environmental stressors.
Post-Soviet Estonian films tend to focus on victimhood and resistance, while ignoring the Holocaust and collaboration with Nazi forces. Films like Awakening and In the Crosswind address deportation complexities, while others draw connections to the Holocaust for international audiences.
An international team of scientists developed a novel, catalyst-free plastic recycling process that uses only water and oxygen to convert various types of plastic waste into high-value organic acids. The method achieved near-complete conversion with minimal environmental impact.
Scientists have discovered that oxygenic photosynthesis is possible with only one photosystem, overturning a long-held assumption in biology. The study, published in Nature Communications, shows that the absence of one photosystem can be compensated by an alternative mechanism.
Researchers discovered that cyanobacteria band together into protective flocs when attacked by predators, a survival strategy that could influence how carbon is stored in the world's waters. This behavior helps explain why cyanobacteria invest energy in forming flocs despite the apparent cost to their growth.
Incorporating structured, video-enhanced feedback into training programs halves prescribing errors by newly qualified doctors. This approach closes the performance gap between novice and experienced prescribers, demonstrates cost-effectiveness and scalability.
Researchers at the Hebrew University of Jerusalem have found that plants can successfully manufacture β-casein, one of the major proteins in cow's milk. The protein accumulated in an unexpected location inside plant cells, revealing a previously unknown pathway that could help improve animal protein production in crops.
Researchers at Johns Hopkins Medicine have found a potential therapeutic target that can improve the potency of decitabine, a chemotherapy commonly used to treat bone marrow disorders and acute myeloid leukemia. By blocking DCTPP1's function with newly identified inhibitors, cancer cells become more susceptible to decitabine's ability ...
Researchers have developed laser-constructed 3D self-supported CoCu metal-organic framework electrocatalysts that exhibit high OER activity and excellent long-term stability. The electrodes display rapid electrolyte exchange, strong electronic interaction, and minimal degradation over 300 hours.
The renowned jazz musician and teacher Terence Blanchard has been awarded the Gutenberg Teaching Award for his exceptional contributions to music education. The award is worth EUR 10,000 and recognizes Blanchard's promotion of an experimental and egalitarian teaching environment.
A mathematical framework based on knot theory characterizes knittability and classifies periodic textile structures based on how defects spread through them. The framework determines whether a textile structure is knittable and classifies different types of periodic textiles by analyzing propagation patterns.
Researchers have demonstrated a technique to fabricate large-area oxide twistronic materials with controlled twist angles and strong chemical bonding between layers. This allows for the creation of high-crystallinity oxide moiré superlattices, which could enable new functionalities in devices.
Researchers Cong Trinh and Seunghyun Ryu receive US Department of War funding to analyze fungal genes and develop new synthetic biology tools for mitigating fungal contamination in critical systems. The grant focuses on Candida species, which can degrade materials used in electronics, vehicles, and fuel systems.
A study analyzing 2.9 million sustainability indicators from 10 years of annual reports found that companies are increasingly disclosing climate data, but coverage of value chains and social factors remains patchy. Sustainability performance and transparency are converging, with a significant increase in disclosed indicators.
This economic evaluation characterizes U.S. lobbying spending in the mental health field from 2014 to 2024, revealing significant growth. The study highlights increasing lobbying efforts in psychiatry and psychology, suggesting a shift towards more prominent advocacy for mental health issues.
Researchers have discovered that naked mole-rat queens release a volatile compound called isopropyl myristate, which induces temporary infertility in other females and prevents rivalry within colonies. This scent also increases levels of prolactin, reducing fertility, while keeping progesterone levels low.
A sub-nanoscale polyoxometalate cluster-functionalized Fe3O4 nanozyme is designed for biomedical applications. The nanozyme exhibits pH-dependent bifunctional catalytic behavior, generating ROS in acidic environments and scavenging excess ROS as the wound environment shifts to physiological pH.
A shift to healthier diets could lead to a significant reduction in global agricultural land use and livestock production value, with potential benefits for human health and the environment. The study suggests that transforming food systems could result in a 42% decline in global livestock production value compared to 2020.
Research by Harvard Medical School found that traffic fatalities increased by 14.3% the day after mass shootings, resulting in nearly 20 additional deaths nationwide. The study analyzed internet search patterns and data from the Fatality Analysis Reporting System to identify a consistent pattern across the country.
Researchers at Columbia's Zuckerman Institute found that specialist neurons exist but are the exception, not the rule. Most neurons can display a huge diversity of responses and help the brain solve complex tasks.
Researchers developed a new allergen-specific IgE test to detect functional antibodies capable of triggering immune responses in food allergies. The improved AlphaCL method overcomes limitations of conventional tests, maintaining strong signal responses even with serum components present.
Research highlights the significant impact of modifiable risk factors on ischemic heart disease mortality in the US. High body mass index (BMI) and fasting plasma glucose levels have increased attributable risk over the study period, emphasizing the importance of addressing these factors to reduce mortality.
A new machine learning version of the Martin-Hopkins equation accurately assesses LDL cholesterol risk with minimal difference to the original, making it accessible to all laboratories. The simplified code enables clinicians and patients to make better decisions about starting treatments that prevent heart attacks and strokes.
A new study has mapped Europe's wetlands, identifying peatlands as the most critical type to restore for climate benefits. The map provides a basis for assessing where wetland restoration could deliver benefits for climate and biodiversity.
Researchers analyzed 17 clinical trials and found little evidence that smokers increase smoking behavior when switching to low-nicotine cigarettes. In fact, most participants smoked significantly fewer cigarettes after making the switch.
A research team developed an electron-injection-softened strategy to regulate the electronic structure of sulfur hosts, achieving a nearly barrier-free cascaded sulfur reduction reaction. This enables the formation of Li2S2/Li2S with high areal capacity and excellent stability.
A new study suggests that ketogenic diets can increase the risk of cancer in the small intestine, unlike their protective effect on colon cancer. The diet's effects are driven by fat metabolism rather than ketone bodies.
Researchers suggest that extreme space weather may have far worse effects on Earth's technology than previously thought. The study, published in Nature, found a direct relationship between solar wind strength and electric currents in the upper atmosphere, indicating no upper limit to Earth's response.
Researchers have found that stimulating a nerve in the external ear may help to ease inflammation in the lungs of mice. The study suggests a novel device could be developed to target inflammatory pathways and treat diseases like asthma, pulmonary fibrosis, and rheumatoid arthritis.
A new study suggests that adopting a flexitarian Planetary Health Diet could prevent around 15 million premature adult deaths per year. The transformation scenario projects a 9% reduction in global agricultural land use and a 60% decrease in livestock production value by 2050.
Research identifies SPP1+ macrophages as key drivers of intervertebral disc degeneration, leading to matrix destruction and disc deterioration. Targeting the SPP1 signaling pathway may offer an effective strategy for mitigating or reversing spinal degeneration.
Researchers have developed a new approach to designing drugs that can target multiple types of cancer cells, significantly improving treatment outcomes in mice. By self-assembling into two antibodies that bind together and attack multiple receptors, the modified antibody-drug conjugates outperformed standard treatments.
MXene terminal groups significantly influence its properties, such as electrical, optical, magnetic, and mechanical behavior. By custom-tailoring these terminal groups, researchers can create MXenes suitable for targeted applications, including thermoelectric materials and superconductors.
A recent study reveals a significant increase in desert dust pollution in southern Europe, with concentrations more than twice as high as in central and northern regions. The study also highlights the potential health risks of elevated desert dust levels, particularly for respiratory problems.
Researchers discovered that niobium diselenide and TaS₂ exhibit two strongly interacting superconducting states, resolving a long-standing mystery about their behavior. This finding provides new insight into superconductivity and could aid in designing better superconducting materials for future technologies.
A recent study published by the University of Sydney found that dexamphetamine and methylphenidate are equally effective in treating ADHD in children, with no significant differences in symptom improvement. However, children taking dexamphetamine experienced greater weight loss compared to those taking methylphenidate.
A Southwest Research Institute-led study proposes a connection between an asteroid collision and an inner-solar-system-wide bombardment episode 800 million years ago. The research suggests that the catastrophic breakup of the Eulalia parent body may have led to widespread impacts on Earth, coinciding with biological and geological chan...
Researchers found a high frequency of MIR142 gene mutations (37.1%) in primary CNS DLBCL, exceeding systemic DLBCL data. The study suggests that these mutations may disrupt miRNA function and require further investigation for potential clinical applications.
AC004854.2 is significantly upregulated in colorectal cancer tissues and correlates with poor clinical outcomes, increased tumor aggressiveness, and reduced overall survival. It disrupts the PUF60–FUBP1 complex and activates c-MYC transcription, driving CRC malignancy.
One in 11 Australian kids has high blood pressure, often symptom-free, which can damage young bodies for years before it's picked up. Lifestyle changes such as improving diet, increasing physical activity, and reducing salt intake can reverse or delay the need for medical intervention.
A comprehensive review in Biomedical Analysis assesses the current state and future of direct mass spectrometry for quality control, safety, and authentication of herbal medicines. The technology offers a dynamic way to ensure the safety and proper processing of potent herbal medicines by monitoring toxic compounds in real-time.
The meeting will explore breakthroughs in diabetes prevention and treatment, as well as innovative approaches to monitoring astronauts' health in space. Researchers will also discuss potential targets for slowing or preventing Alzheimer's disease in people with Down syndrome, and advancements in cervical cancer screening.
A buildup of bile acids caused by an unhealthy gut can drive breast cancer to other parts of the body, researchers reveal. The study found that replenishing beneficial bacteria or treating patients with FDA-approved bile acid sequestrants may reduce breast cancer metastasis.
A federal nicotine reduction strategy could drive U.S. smoking rates below 1% in 14 years, preventing millions of premature deaths and boosting productivity by $298 billion. Implementing such a policy would also significantly close smoking disparity gaps for individuals with major depression.
Researchers developed a nanoparticle system that uses cancer cells' own copper resources to activate cuproptosis, eliminating tumor cells while protecting healthy tissue. The targeted nanoparticles showed enhanced cellular uptake and were more lethal to breast cancer cells than non-targeted versions.
Researchers tested 54 avocado oil-labeled products and found 48 contained other oils. The study used fatty acids and sterols to verify authenticity, but 89% of products still failed due to adulteration. Food companies may not detect adulterated oil without rigorous testing.
Astronomers have discovered a third planet, Beta Pictoris d, in the system, which is 100 times fainter than Beta Pictoris b and 2.4 times more massive than Jupiter. The planet's wide orbit and extreme faintness make its detection a significant achievement.
The symposium marked the hospital's designation as a research-oriented hospital, featuring discussions on collaborative research ecosystems at various levels. Participants engaged in sessions covering future directions, strengthening regional and industry collaborations, and real-world cases of research commercialization.
A scoping review suggests astrocytic dysfunction may precede neuronal degeneration in CTE. Astrocytes' dysregulation contributes to the development of CTE's characteristic features through mechanisms including astrogliosis, disrupted waste clearance pathways, and chronic neuroinflammation.
A new study by Hanyang University researchers found that carbon-based pricing can increase pro-environmental behavioral intentions among tourists. Participants who knew wasteful consumption could increase their costs reported stronger conservation intentions.
The study reveals that local political connections and strong NGO support are crucial for securing formal recognition of customary land rights. Communities with influential leaders and advocacy organizations like AMAN tend to succeed, while those without face significant hurdles. The researchers propose simplifying bureaucratic procedu...
The Reticular Science Prize for Emerging Scholars and Innovators is awarded biennially to researchers with ten years or less of post-doctoral experience. The inaugural award will be presented at EuroMOF 2027, with a silver medal, $2,500 monetary award, and a certificate signed by the selection committee members.
Researchers from 12 countries have launched a global effort to document and study 'heritage' diets before they are lost. These diets, shaped by local environments and traditions, may hold vital clues to better health.
Research reveals a link between socio-economic factors and health outcomes for adults with congenital heart disease, highlighting the need for improved access to specialized cardiac care.
Research finds biodiversity delivers largest gains under extreme drought in drier grasslands, with stronger effects from species complementarity. In contrast, forests show no comparable context dependence under extreme drought.
Hydrogen displays varying behavior when in vanadium, but researchers have now discovered the role of crystal symmetry in controlling its quantum behavior. Highly symmetric structures allow hydrogen to tunnel between sites, while distorted structures suppress this effect.
A new collaborative study found loneliness strongly linked to poorer mental health and lower wellbeing, as well as worse general health. The research suggests that supporting people who feel lonely or socially isolated could help improve mental health and overall health.
Annual Reviews expands its event capabilities by acquiring Underline Science, enabling it to support scholarly societies and conference organizers globally. The acquisition combines conference expertise with AR's existing research community engagement, allowing organizations to strengthen stakeholder engagement and reach new audiences.
A new class of photoswitchable small molecule drugs has been developed to restore key visual functions in animal models of blindness. These compounds mimic the function of photoreceptor cells and show remarkable effectiveness at restoring sight using a simple and potentially patient-friendly approach.
Researchers found that brain-computer interface training improved the perception of smaller visuo-motor errors, whereas traditional behavioral training only enhanced detection for larger rotations. The training also showed contributions from brain regions controlling decision-making and visuospatial processing.
Research finds that medaka sperm velocity decreases by 20% after consecutive spawning, impacting fertilization rates. Sperm counts also vary between single and multiple-mating groups.
Researchers have developed a new version of the Daydreaming algorithm, which combines learning and cleaning to improve artificial memory systems' reliability even with biased data. The algorithm focuses on differences between pixels, allowing it to work effectively with strongly biased data, similar to real-world conditions.
A blood-based test for the biomarker p-tau217 has been shown to predict the risk of developing cognitive impairment due to Alzheimer's disease up to a decade earlier than previously thought. The study found that individuals with very high levels of p-tau217 had a 38% absolute risk of developing cognitive impairment over five years, and...
A new large-scale study estimates that roughly one-third of women experience perimenopause uncertainty, which is prevalent due to knowledge gaps, symptom confusion, and healthcare barriers. The study found that younger women are more likely to cite knowledge gaps, while older women face greater challenges with accessing care.
A study found microplastics in 92% of deep-sea snails and mussels from hydrothermal vents over 2,000 meters below the surface. The presence and accumulation of microplastics vary depending on feeding behavior and regional differences in ocean circulation.
A blood test measuring phosphorylated tau 217 (P-tau217) can estimate an individual's risk of developing cognitive impairment over 2, 5, and 10 years. Higher P-tau217 levels are associated with increased risk of progression to cognitive impairment in cognitively unimpaired older adults.
Researchers found that elephants' bone-conduction hearing is significantly improved due to their larger middle ear structures and ability to voluntarily close their ear canals. This allows them to transmit lower frequency sounds to the cochlea, enhancing low-frequency hearing by up to 30 times