A study has identified a set of plasma proteins that can be used to diagnose and monitor patients with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD). The researchers created a molecular disease trajectory, which identifies key sets of genes involved in the disease progression.
A new review article proposes a gene-to-landscape framework to assess aquatic ecosystem health, predicting collapse and tipping points. The framework spans four interconnected scales, integrating molecular signals and landscape stability for early warning systems.
A recent breakthrough allows independently trained AI models to trade capabilities and boost overall performance when merged into a single system. By modifying just one core layer, the 'SyMerge' framework enables mutually beneficial synergy between models, solving the long-standing problem of task interference.
Scientists developed a 2D thermo-optic modulation platform using QD film based micro-ring resonators, achieving a 19.77-fold increase in tuning sensitivity and a 50-fold improvement in modulation speed compared to conventional devices. The hybrid system enables real-time high-speed reconfiguration with enhanced performance and reduced ...
Flexible electromagnetic induction-type tactile sensors offer a promising route for low-power, robust and self-powered interfaces. The researchers provided a systematic roadmap for development, including application-oriented design and multimodal integration with other sensing mechanisms.
A new mixed-frequency heterodyne demodulation (MHD) architecture has been developed to address limitations of existing multi-gas LITES systems. The novel architecture enables simultaneous detection of two gas species, achieving low-crosstalk detection and excellent linearity.
A new study reveals that tiny gaps in ultra-thin devices can strongly influence unwanted electrical leakage. Researchers found that conventional expectations about insulating materials can change at the atomic scale, requiring engineers to consider the full device structure.
A Hong Kong-based research team found that home-based exercise videos increase children's moderate-to-vigorous physical activity by 6-7 minutes. Parent support strategies grounded in Self-Determination Theory also help sustain motivation and meet psychological needs, leading to improved overall physical activity levels.
A new study tracks the spatiotemporal evolution of photogenerated holes in a facet-engineered bismuth vanadate photocatalyst. The research reveals three sequential steps: ultrafast charge separation, defect-state trapping, and rapid interfacial hole transfer mediated by oxygen-related defects.
Researchers developed nanoparticles that retain their protective coating in normal tissue but shed it upon reaching tumor tissue, releasing anticancer drugs. This technology reduces systemic side effects and enhances treatment efficacy.
A simple outdoor flood alarm is being developed by a UT Hydrology professor to detect life-threatening floods as water rises on individual properties. The low-tech alarm triggers a loud warning and light when water reaches a preset height, making it reliable during emergencies.
A new study of penguins and krill found that repeated predator disturbance can alter prey behavior, leading to functional prey depletion. Penguins had to dive deeper and travel farther to encounter prey, but feeding rates remained unchanged once prey were encountered.
A study found that some toad populations recover from a deadly fungus due to the early maturation of antimicrobial peptides in their tadpole stage. This immunity allows them to survive as adults, suggesting that environmental factors such as temperature may play a role in disease progression.
A new study by University of Notre Dame economist Santosh Kumar Gautam found that India's universal immunization programme significantly reduced infant and under-five mortality rates. However, the programme had mixed effects on educational attainment, with some regions seeing increased primary school completion while others experienced...
The strategic alliance combines Insilico's Pharma.AI platform with Bora's global capabilities to explore a next-generation drug innovation model. The partnership aims to accelerate Bora's transition towards AI-driven drug discovery and development, leveraging Insilico's comprehensive research and development strategies.
Researchers developed a high-resolution monitoring approach combining drone-based multispectral imaging with ensemble machine learning models. The method revealed how surrounding industrial, agricultural, residential, and green areas influence water quality in urban rivers.
A new study reveals that macrophages, a key immune cell type, age differently across tissues and between sexes. The researchers found that aging macrophages become more focused on responding to stress and cellular damage, but lose some molecular programs involved in maintaining healthy tissue structure.
Researchers created a platform to study chronic pancreatitis pathogenesis and identify potential treatments by generating patient-derived organoids. The organoids revealed consistent dysfunction in the CFTR protein, which may be a future effective therapeutic target.
A gene therapy approach has restored several disease-relevant traits in a mouse model of fragile X syndrome, including reduced seizure susceptibility and improved brain activity markers. The study's findings suggest that restoring the FMRP protein could improve symptoms such as sensory hypersensitivity and repetitive behavior.
Patients who suffered a serious heart attack had higher levels of micro and nanoplastics in their blood compared to those with chronic ischemic heart disease and normal coronary arteries. The study also revealed that people exposed to higher levels of air pollution and smokers had higher levels of microplastics in their blood.
Higher cultural engagement is associated with lower physiological ageing and improved health markers. Adults who participate in frequent cultural activities have a younger physiological age, suggesting that cultural engagement can help support healthy ageing.
Researchers developed Buffer-and-Reinforce framework to preserve AI safety during personalized fine-tuning, maintaining high safety even in extreme settings. The framework achieved strong customized performance and state-of-the-art safety without additional safety data or increased computational cost.
Astronomers at Durham University have discovered the most distant example of a compact, star-forming structure at the heart of a galaxy, dating back over nine billion years. This finding reveals clear evidence of a nuclear disc forming at an early stage in cosmic history.
A study found that children born during the first COVID-19 lockdown in England had lower executive function skills, including difficulty focusing and regulating emotions. Overall language scores were at or above expected levels, but expressive language skills were below average.
A study on the lemon frost gecko, a pet reptile prone to aggressive tumours, has identified genomic changes associated with cancer. The findings may provide insights into why some animals are more susceptible to cancer than others.
The NSF Engines award will support QuantumCT's technology translation, workforce development, and incubator operations. The funds will also facilitate industry and community engagement to deliver broad societal benefits, including economic opportunities and innovative technology.
A new compound called ampyrone safely increases melanin production in human skin, offering a potential treatment for hypopigmentation disorders. The discovery could improve visual function and enhance patient quality of life for those with severe genetic forms of albinism.
The Resilient Energy Technology and Infrastructure Consortium will develop innovative ways to meet the nation's growing energy needs, generating 21,000 jobs and $1 billion in economic growth. The consortium will focus on advanced manufacturing, AI, cybersecurity, and energy technology.
Researchers from the University of Nebraska-Lincoln have identified a specific gut bacterium, Bacteroides uniformis, and its metabolites that can positively impact the body's immune response to cancer. The study found that these metabolites can suppress tumor growth and boost anti-tumor immunity in mice.
A study published by University of Cincinnati associate professor Nelly Elsayed highlights the importance of human review in AI-driven physicians' documentation to ensure transparency, privacy, and reliability. The research also emphasizes the need for clinicians to be trained on software before adoption to curb errors.
A recent study published in the Journal of the American College of Surgeons found that older adults who undergo high-risk emergency general surgery spend significantly fewer days living independently at home after surgery. The researchers analyzed outcomes for nearly 30,000 individuals aged 66 and older using a patient-centered measure...
A new study published in the Journal of the Royal Society Interface reveals that grazing animals like cattle and sheep can create elaborate terracettes, staircase-like ridges on hillsides. The research challenges a long-held assumption that wandering livestock cannot restructure landscapes on a large scale.
Researchers created a comprehensive single-cell map of the tumor immune microenvironment in multiple myeloma and its precursor conditions. The study identified five distinct subtypes, or 'ecotypes,' that capture meaningful insights into signaling pathways and genetic programs not fully explained by disease stage alone.
Scientists create a map of regolith thickness across the Moon using data from over 300 impact craters and lunar missions, estimating six meters in highlands and four meters in maria. This research provides valuable insights for future lunar exploration, including considerations for mission planning and resource utilization.
Researchers uncover how a family of tick-borne viruses, known as orthonairoviruses, evade the immune system by manipulating cellular communication pathways. This study highlights a significant pandemic risk posed by these viruses and emphasizes the need for continued surveillance and preparedness.
Eight Fred Hutch researchers will receive funding for projects guiding pancreatic cancer treatment decisions, improving CAR-T effectiveness, and stopping acute myeloid leukemia development. The Evergreen Fund, an internal grant program, aims to accelerate translational discoveries to commercial viability.
Karen Bernstein, co-founder of BioCentury Inc., has been elected as the new chair of Critical Path Institute's (C-Path) Board of Directors. She succeeds M. Wainwright Fishburn, Jr. Bernstein brings her expertise in drug development and analysis to the role, having worked in the biopharmaceutical sector since 1987.
A new study suggests that hair can significantly influence the effectiveness of personal decontamination procedures in biocontainment facilities. Researchers found that a minimum standardized shower time may be necessary for effective removal of non-enveloped viruses, and that hair products with low or no detergent activity showed litt...
The University of Cincinnati launches the Center for Alzheimer's and Neurodegenerative Diseases Research (CANDR) to improve dementia prevention and treatment outcomes. CANDR aligns with UC's mission to innovate and engage locally while addressing one of the region's most pressing public health challenges.
The University of Tennessee has won up to $160 million for the BRIDGES Engine, a collaborative initiative driving rural economic development in Tennessee and Alabama. The project aims to generate millions of dollars in additional annual income for farmers and create thousands of jobs across the state.
A new review calls on Mexico to add liver health to its existing chronic disease programs, citing the country's high liver disease prevalence. Liver disease affects nearly half of Mexican adults and is linked to diabetes and obesity.
A new review suggests that China's carbon reduction commitments can influence the environmental performance of the global palm oil industry by promoting sustainable production, traceability, and climate-responsible technologies. This could help reduce palm oil's climate footprint while protecting livelihoods.
Thirty-six Bentham Science journals have recorded significant increases in Impact Factor, highlighting their prominence in clinically urgent and scientifically dynamic disciplines. This reflects the global research community's recognition of these journals as publishers of consequential science.
Researchers have developed pressurized sand dampers that can withstand extreme temperatures and provide a cost-effective solution for structures. These dampers can be replaced or repaired quickly, reducing economic losses from vibrations in high-rise buildings.
A new study reveals that a small group of highly connected microorganisms helps maintain essential ecosystem functions, such as carbon and nitrogen cycling, despite major shifts in the wider microbial community. The research found functional redundancy, where different microorganisms can perform similar ecological roles.
Researchers outline a future vision for VR research that prioritizes open science practices and technological accessibility. The Openverse protocol addresses interoperability, procedural standardization, and data sharing to improve VR study quality and address the reproducibility crisis.
A new study has developed an inexpensive and rapid method for measuring placental volume using two-dimensional ultrasound equipment. The Estimated Placental Volume (EPV) method shows near-perfect correlation with the current gold standard, making it a promising alternative for identifying pregnancies at risk of stillbirth.
A consortium of nearly 100 partners in Oregon will receive up to $160 million from the NSF to grow the state's semiconductor ecosystem. The initiative aims to accelerate innovation, advance energy grid security, and boost regional economies.
Researchers created new metal alloys using AI-driven materials design, retaining strength under extreme conditions. The alloys, made of nickel, cobalt, and chromium, outperformed industry standards in properties such as puncture resistance and oxidation resistance.
Researchers at MIT have developed a microscopic pixel-based tunable lens that controls incoming infrared light for more precise thermal imaging, chemical sensing, or pollution monitoring. The system enables compact, dynamic infrared cameras with potential applications in environmental protection, space research, and military technology.
A team of researchers has developed a new chemical approach that converts a mixture of the three most common plastics directly into high-purity hydrogen fuel at temperatures far below conventional gasification. The process locks carbon dioxide away as a solid mineral without releasing the greenhouse gas into the atmosphere.
A new study found that racially minoritized graduate students believe state anti-DEI laws alter their experiences in racial/ethnic organizations. Many faced funding and event planning impacts, with institutions lacking support for navigating these challenges.
A new study reveals that menopause symptoms such as cognitive impairment and emotional wellbeing are more commonly discussed on Reddit than in clinical records. The study highlights the importance of online forums in capturing stigmatized or poorly understood conditions like perimenopause and menopause.
The University of Rochester-led NSF STELLAR Engine launches to strengthen US competitiveness in global markets by advancing lasers and laser application research. The project aims to bring New York laser research, development, and manufacturing to a scale that can compete globally.
OYE Therapeutics announced positive Phase 1 results for OYE-101, a proprietary intravenous caffeine formulation. The study demonstrated the safety and tolerability of OYE-101 in healthy adult volunteers, supporting its planned development as a treatment to support emergence from general anesthesia and deep sedation.
Dr. Griffin is evaluating a hybrid substance use prevention intervention using classroom materials and e-learning modules to supplement Life Skills Training Elementary School prevention program.
The Data Sciences Institute at the University of Toronto has been awarded $1 million in Claude API credits to support AI-enabled research. Researchers will gain access to cutting-edge AI tools, enabling discovery, analysis, and innovation across disciplines.
Athletes with ADHD face unique concussion challenges, requiring more scrutiny for diagnosis and recovery. The study suggests a longer recovery period, up to four to six days, and highlights the need for tailored return-to-play decisions.
Researcher T. Reid Nelson is conducting a study on striped bass to better understand the environmental factors influencing mortality following catch-and-release. His findings aim to provide a more accurate estimate of catch-and-release mortality, essential for effective fisheries management.
Researchers analyze how technology has shaped the retail investment market in the US, noting dramatic drops in costs but persistent structural hurdles. The study concludes that technological advancements introduce complex regulatory challenges regarding jurisdictional oversight and investor protection.
Researchers found that methane emissions from Amazon wetlands are four times higher than previously calculated, with river deltas producing up to 26% more methane. The study uses aircraft measurements and high-resolution data to provide a comprehensive understanding of methane sources in the region.
A study published in American Psychologist found that White children who consumed media with fewer Black characters had less positive attitudes towards Black children and were more likely to attribute racial inequalities to differences. The research highlights the role of media consumption in shaping childhood prejudices, suggesting th...
Researchers recommend global framework for monitoring and managing novel entities, including tailored target values based on hazard potential. A three-step evaluation process assesses production, environmental behavior, and impacts of these substances.
The report provides an ecological characterisation of two contrasting habitat groups: inland peat-forming wetlands and coastal lagoons. Hydrology is identified as the dominant control on ecosystem functioning, with a persistently high water table sustaining anoxic conditions in peatlands.
A new study found that a virtual smoking cessation treatment program nearly doubled quit rates for cancer patients who currently smoke. The program, delivered at community oncology care settings, was both cost-effective and satisfying for patients. Participants who completed more sessions had a higher likelihood of quitting.
A study presents a methodology to identify profiles of greater biological and clinical vulnerability in children and adolescents who have been subjected to child maltreatment. The study identified three biomarkers: high diurnal cortisol levels, elevated serum C-reactive protein, and a higher waist-to-height ratio.
A novel AI model called BINND has been developed to predict which DNA molecules bind to each other. The model achieved an accuracy of 83.5% in predicting DNA pairs that would bind, surpassing the state-of-the-art model by at least 10%. This improvement has significant utility for biomedical diagnostic tools and DNA computing applications.
Researchers at Heidelberg University demonstrate acoustic manipulation to create functional vascular networks and self-organizing blood vessel-like structures in vitro. The team defines quality requirements for generating complex multi-cell-type tissue relevant for biomedical studies and regenerative medicine.
Researchers found that integrating electronic health record training into coursework increased overall satisfaction and confidence in clinical readiness. Students with prior exposure to EHRs reported stronger perceptions of preparedness for clinical training, leading to reduced technology-related stress on experienced clinicians.
A new article by Yong Zhao argues that education needs a new response to artificial intelligence and a new theory of how schools can change. He proposes the 'courageous minority' approach, which suggests that small groups of teachers, students, and community partners can create meaningful alternatives in their existing spaces.
A recent study using advanced PET scans has found widespread synaptic density loss in individuals with schizophrenia, particularly in areas rich in neurotransmitter receptors. The researchers identified distinct patterns of synaptic loss that follow the brain's molecular and connectivity architecture.
Researchers at UCF College of Engineering and Computer Science developed CRAFTS, a plug-and-play software that simplifies engineering design. The software offers a user-friendly interface and modularity, making it accessible to users without extensive coding knowledge.
Researchers suggest separate weight-driven tables for different types of defendants, eliminating disparities in crack and methamphetamine sentences. The study proposes alternative approaches to define relative sentences for psychostimulants and opioids based on harms associated with each type of drug.
Researchers at The University of Manchester discovered that carefully controlling thermal conditions during molten metal deposition (MMD) can reduce defects and improve the final material structure. By adjusting nozzle and substrate temperatures, they found a strong relationship between grain size and porosity, providing valuable insig...
A new study has identified 50 previously unknown subfamilies of myosin genes that drive subtle differences in muscle function among various animal species. The findings suggest that the evolution of animals is not solely driven by external appearance, but also by factors nested beneath the surface.
A recent study on nursing students' social media usage suggests that purposeful academic engagement enhances wellbeing, while compulsive recreational use erodes it. Academic use of social media was associated with higher life satisfaction, lower addiction risk, and better overall wellbeing.
Researchers found a slight association between GLP-1 medications and ischemic optic neuropathy, a condition causing reduced blood flow to the optic nerve. The risk remains low, but clinicians should be aware of this potential association, particularly in patients with Type 2 diabetes.
A new tool generates realistic monkey body animations, revealing an uncanny valley effect where macaques prefer less realistic avatars to highly realistic ones. The study provides the first evidence that non-human primates experience this phenomenon.
A global study attributes nearly two million premature deaths worldwide to ultrafine particle pollution, with cardiovascular disease being the main cause. The exposure map reveals high levels of ultrafine particles in urban and suburban areas, particularly in Southern and Eastern Europe.
The American College of Chest Physicians (CHEST) submitted comments on proposed federal policies governing research grants, emphasizing the need for stable funding and predictable oversight. The organization argues that policy changes could compromise the continuity of scientific discovery, ultimately weakening patient care.
Dr. Renato M. Silva has been selected as the new dean of UTHealth Houston School of Dentistry, succeeding John A. Valenza. He brings a rare combination of scientific distinction, clinical expertise, and leadership experience to the role.
Researchers unveiled a technique to build ultra-clean 2D heterostructures using muscovite crystals, eliminating microscopic residues that disrupt electronic device performance. This method enables precise stacking of atomic layers, leading to new properties and potential breakthroughs in quantum computing and nanoelectronics.
Researchers at KAUST developed a wearable microneedle patch that continuously tracks drug levels beneath the skin and wirelessly transmits data to a smartphone. The platform provides continuous information about therapies inside the body, offering a more complete picture of how medicines move through the body over time.
A new national study reveals that about two-thirds of federally qualified health centers (FQHCs) offer prenatal care, while one in three do not, highlighting missed opportunities to address inequities in maternal health access. The study underscores the critical role of FQHCs in caring for low-income and racially diverse pregnant popul...
A recent study found that nearly 9 in 10 pregnant participants struggled to place their seatbelts correctly, despite instruction and guidance. The researchers highlighted the need for updated restraint system designs to accommodate changing female anatomy during pregnancy.
A new GSA report emphasizes the critical role of primary care providers in detecting and managing cognitive decline, with a focus on actionable insights for clinicians. The report highlights advances in diagnostic technology and modifiable lifestyle factors linked to brain health outcomes.
Researchers at the University of Illinois Chicago have developed a new imaging method that allows scientists to see previously hidden enzyme activities in small regions across the whole cell. The technique, dubbed Fluctuation Increase Negated by Intra-Chain (FINICI), flips the optical readout of negative biosensors into positive, reada...
Researchers discovered a previously unknown damage mechanism in metals under shear loading, where stiff particles inhibit material movement and boost void growth. The study used synchrotron computed laminography and 3D simulation methods to investigate an aluminum alloy and found significant damage growth up to sixfold.
The study creates a radiohybrid approach that labels a single molecule with two different diagnostic radionuclides, enabling long-term visualization of therapeutic agent distribution. This allows for personalized cancer medicine by calculating optimal radiation doses for individual patients.
A new study found that honey bee larvae lack the sophisticated olfactory capabilities of adult honey bees. Adult bees have a suite of chemosensory receptors, including olfactory receptors and ionotropic receptors, essential for detecting odors from potential sources of pollen and nectar.
A Tel Aviv University study proposes that the Qumran sect used a 364-day calendar for over two decades before abandoning it due to its mathematical imperfection and improved relations with Hasmonean leadership. The calendar's daily deviation from the astronomical year accumulated rapidly, posing practical problems for the community.
A new AI-based system called ShadowSense learns from real-world data to predict short-term changes in solar module power output. The system outperforms conventional methods with an accuracy rate of over 92%, providing valuable insights for electricity grid management.
Threats to academic freedom are increasing, including attacks on individual researchers and specific fields of study. Research vulnerabilities can be strengthened through cooperation among scientists, businesses, and civil society.
A review of hundreds of studies suggests that polyphenol-rich foods like berries, tea, and olive oil may support healthy brain aging by reducing inflammation and promoting nerve cell function. While no single food can prevent Alzheimer's disease, a balanced diet rich in plant-based foods may help preserve cognitive function over time.
New research highlights that modern slavery is often a result of business decisions prioritizing cost and efficiency over labor conditions. Companies must invest in understanding their supply chains to tackle exploitation and shift focus from reporting to knowledge.
New research shows that tadpoles adapt their diet in response to rising temperatures, consuming more plant material and eating overall. However, this natural strategy becomes less effective as temperatures continue to rise, with consequences for growth, development, and survival.
A new study found that adults with disabilities have more than three times the rate of alcohol use disorder diagnoses compared to adults without disabilities in the US. Adults with serious mental illness and acquired brain injuries had the highest rates of AUD, with men with disabilities having the highest rates.
Researchers at the Netherlands Institute for Neuroscience are working to understand how the brain regulates stress and developing new treatments for conditions like PTSD and anxiety disorders. They aim to identify brain regions that can be targeted to teach people to better control their stress responses through neurofeedback.
A qualitative study reveals that watchdog science journalism is labour-intensive and time-consuming, with high thresholds of evidence and significant barriers to access. The findings highlight the need for media organisations to protect specialised investigative work and foster a more transparent public discussion about science.
Researchers discovered a new signaling pathway allowing plants to adjust protein production in minutes, not hours. Short sequence elements in messenger RNA act as molecular switches, enabling direct regulation of protein synthesis.
A new 3D computer model developed by the University of Surrey has shown how Pseudomonas aeruginosa grows and spreads its protective layer under constant fluid flow. The model's accuracy was validated through laboratory experiments, demonstrating potential for faster and smarter ways to understand bacterial behavior.
A new species of harvester ant, Messor odrysarum, has been discovered in the Eastern Rhodopes region of Bulgaria. The species is part of the Messor genus and has distinctive physical traits compared to its close relatives.
The partnership generates valuable bathymetric data through vessel operations and lost crab trap removal, enhancing navigational safety and coastal models. The new dataset will be publicly available for researchers, agencies, and coastal managers to support commerce.
A new study published in Hepatobiliary Communications reveals that standard CT scans can detect stage-specific tissue patterns predicting severe liver complications in chronic hepatitis B-related cirrhosis. Visceral fat and muscle shifts carry different warning meanings based on the patient's disease stage.
Researchers identified a new biological vulnerability in KMT2A-rearranged B-cell acute lymphoblastic leukaemia, which could lead to more effective treatments. Blocking the interaction between two proteins slowed leukaemia progression and enhanced conventional treatment efficacy.
A global study found that plant evolutionary history plays a stronger role in shaping nonstructural carbohydrate (NSC) storage than current environmental conditions. NSC variability is organ-specific, with leaf NSCs increasing toward higher latitudes and stem and root NSCs declining.
The proposed OMB rule change would fundamentally alter how federal research funding is allocated in the US, compromising research independence and restricting international collaboration. PLOS argues that costs linked to making research available should be assessed against public and economic value, rather than being unallowable.
A world-first lens has been developed to focus neutrons into a single focal point, overcoming the challenge of defocusing weakly interacting particles. This allows for high-resolution imaging with a resolution below twenty micrometers, opening up new possibilities for materials science and device analysis.
A joint KAIST–University of Tokyo research team found that temperature-related suicide mortality is expected to rise globally due to climate change. Regional differences in future rises are driven by varying temperature-suicide relationships, with East Asia and South America projected to see relatively small increases.
A new review framework redefines how hard carbon anodes are engineered in sodium-ion batteries. By optimizing each stage of the fabrication chain, researchers achieve improved performance and reduced costs.
Scientists are conducting a European clinical trial aiming to reduce antibiotic use and lower recurrent urinary tract infection rates by targeting pathogenic E. coli strains with CRISPR-enhanced phage cocktails and microbiome restoration therapies.
The Netherlands Institute for Neuroscience launches a grant programme to support joint research projects between fundamental neuroscience and clinical psychiatry. The aim is to improve understanding of brain changes in psychiatric disorders, paving the way for more accurate diagnoses and targeted treatments.
Researchers at Nagoya University review the latest results of plasma agriculture, finding that well-tuned plasma treatments boost seed vigor or yield in over two-thirds of studies. Plasma-induced epigenetic changes also promote positive expression of plant genes involved in germination and stress tolerance.
The integration of biomass-derived materials provides an innovative solution to overcome the limitations of solid-state batteries, including high fabrication costs and environmental footprint concerns. By repurposing natural structures, researchers have discovered structurally sophisticated biopolymers that possess naturally hierarchic...
Researchers at Technion-Israel Institute of Technology discovered that mature, aged cells can revert into active stem cells that regenerate damaged tissue. This finding challenges the prevailing view on tissue regeneration and implies the possibility of therapies promoting natural healing mechanisms.
The Japan Institutional Gateway platform is now available to researchers across Japan, enabling the publication of Japanese-language research at world-class speed and reliability. This expansion aims to support the acceleration of the open research movement promoted by the Japanese government.
A study from Binghamton University found that poor sleep quality is connected to hyperarousal in young people and neurodegenerative patterns among older women. Research analyzed brain scans from over 1,300 participants to see how brain networks connect at rest in those with poor sleep.
Researchers from Fuzhou University review the potential of Atomic Layer Deposition to regulate interfacial chemistry in zinc-ion batteries, enabling durable high-performance systems. The technique's unique conformality and precision make it suitable for layer-by-layer growth of atomic films on complex battery components.
Researchers found ulinastatin significantly exerts hepatoprotective effects by inhibiting cytokines, reducing cell death and oxidative stress, and regulating immune function. It also adjusts enzyme activity involved in blood clotting and fibrinolysis system, showing potential as supportive treatment for liver diseases.
A sustainable management model is proposed for the Duernas Saltworks to preserve its geological heritage, cultural landscape and support rural development. The model aims to balance conservation, artisanal production and community engagement.
The Three Gorges region recorded its second-hottest year on record in 2025, with an average temperature 1.1°C above normal, and the most extreme autumn rainfall in 43 years. Persistent heatwaves and torrential rains caused widespread flooding and posed new challenges for disaster prevention and engineering project safety.
Researchers developed an ultrasensitive electrochemical biosensor to detect early-stage liver fibrosis using only a small amount of blood, providing a non-invasive diagnosis method. The sensor achieved high sensitivity and accuracy, distinguishing between healthy individuals and patients with 95.24% sensitivity and 100% specificity.
Research found that severe workplace violence incidents are concentrated in busy daytime periods, outdoor activities, and specific ward areas. The study suggests that everyday ward routines, situations, and environmental factors contribute to the risk of workplace violence.
Researchers developed a novel dual-frequency fiber-array photoacoustic computed tomography (PACT) technology, enabling high-resolution imaging of the entire brain and centimeters deep. This innovation overcomes the limitations of conventional PACT systems, allowing for precise functional imaging and metabolism assessment.
Researchers have discovered a complex layering system around phytoplankton cells, with water-repellent substances concentrated near the surface. This finding has significant implications for models of interactions between phytoplankton and bacteria, and could improve our understanding of the oceans' carbon cycle.
Researchers discovered bio-metals in the jaws of ancient sea worms, exhibiting properties like hardness and strain mechanics. The unique materials show similarities to metals but also have distinct mechanical properties.
A study found that nearly half of preterm children did not meet expected attainment levels in writing and maths by age 6-7, while social deprivation and maternal smoking during pregnancy are linked to lower attainment. Strategies to address social inequalities and support preterm children are vital to improve outcomes.
Researchers investigated hantavirus infection's neurological effects, finding that they can be severe and uncommon. The study aims to improve understanding of the pathophysiology, identify therapeutic targets, and develop management guidelines for these manifestations.
Experts recommend implementing safer technologies and modernizing radiation safety standards to reduce preventable radiation exposure and orthopedic injuries. The consensus statement emphasizes the need for mandatory action to prioritize protecting healthcare workers, ensuring a healthy workforce for patients' access to lifesaving care.
A cohort study reveals that colorectal cancer treatment delays are associated with increased metastasis risk. This finding highlights the need for integrated care and tailored benchmarks for treatment initiation to improve timely and equitable care.
AI model improves cardiac MRI interpretation, while immersive VR simulators aid poststroke rehabilitation. Meanwhile, menopause tracking apps offer empowerment but also pose risks due to inaccurate information and targeted marketing.
Researchers found that colossal karst sinkholes help preserve the rare Magnolia aromatica tree while limiting gene flow and diminishing its long-term evolutionary potential. The study suggests that conservation strategies should protect both individual habitats and connections among populations.
The study found associations between mitochondrial heteroplasmy and cardiometabolic parameters in patients with metabolic syndrome. Intermediate heteroplasmic mutations were associated with the degree of vascular stenosis and lipid metabolism parameters.
Researchers developed a prototype device that autonomously synchronizes distant qubits using a common source of correlated light particles, confirming a 20-year-old prediction. The approach requires no active control or measurement, making it fully autonomous and potentially boosting quantum technology.
Researchers propose a new perspective on ARDS pathogenesis, arguing that multiple forms of regulated cell death communicate through extensive molecular crosstalk. This crosstalk collectively drives lung inflammation and respiratory failure, highlighting the need for network-based therapeutic strategies.
Researchers are developing an AI-driven controller for hybrid microgrid systems that integrates multiple energy sources and storage systems. The system aims to increase efficiency of electrical grids used for data centers and other mission-critical loads.
Hepatocellular carcinoma (HCC) gene signatures can predict prognosis and respond to immune checkpoint inhibitors. However, validating these signatures across different platforms and overcoming ethical concerns hinder their widespread adoption. Integrating multi-omics approaches with liquid biopsy holds promise for personalized therapy,...
Researchers successfully acquired diagnostic X-rays in space, expanding crew health capabilities and paving the way for mission-critical non-medical tasks. The study found that portable X-ray machines are feasible in space, with no significant differences in image quality between pre-flight and inflight images.
A recent study from the University of Cambridge predicts that space launch costs will plummet over the next few years, falling more than 90% by 2040. The cost of sending a kilogram of payload into low Earth orbit is expected to drop from $3,868 last year to as little as $273 per kilo by 2040.
A study published in Anesthesiology found that nerve blocks do not cause nerves to become more sensitive or lead to worse pain after the block wears off. The researchers suggest that rebound pain is caused by the return of surgical pain as the block resolves, rather than hypersensitivity. This finding supports the continued use of nerv...
Researchers discover that emerging tick-borne viruses can escape the human immune system by producing enzymes that remove proteins attached to human proteins, rendering them undetectable. This finding has significant implications for developing a surveillance system to monitor these viruses and potentially mitigating large outbreaks.
A team of scientists has created a method to identify mineral biosignatures on other worlds using Raman spectroscopy. The technique uses machine learning to analyze features of the spectrum, such as band positions and intensities, to determine whether a mineral was formed biologically or abiotically.
A new study from UT San Antonio finds that emergency call takers' word choice can predict depression and anxiety symptoms, while positive expressions are often suppressed in high-stress professions. The research uses natural language processing to evaluate the psychological well-being of a critical but under-researched workforce.
Research by Cornell University found that China's efforts to improve water quality led to a 58% drop in agricultural value added and reduced hiring of agricultural workers in upstream counties
Rocket launch costs have decreased by 21.2% for every doubling of cumulative payload sent to orbit, driven by technological learning. By 2040, costs could reach $300 per kilogram, with SpaceX's Starship potentially pushing costs below $1,000.
Researchers have developed a detector that delivers high sensitivity while operating at ordinary room temperature, using carbon nanotubes and a pyroelectric lithium niobate crystal. The device surpasses earlier graphene-based detectors by several orders of magnitude and offers a broad spectral range without cryogenic cooling.
A study published in PLOS One reveals fluctuations in exclusionary nationalism in prewar Japan through changes in foreign place name writing. Notable turning points coincided with key political events, such as the appointment of a pro-international cooperation Foreign Minister and military coups.
A team of surgeons used robot-assisted stereotactic surgery to treat a patient with multiple deep brain abscesses, achieving complete resolution and rapid neurological recovery. The minimally invasive strategy reduced surgical trauma and accelerated healing.
Researchers mapped the habitat of army cutworm moths to protect grizzly foraging sites from growing backcountry recreation. The moths congregate in high-altitude talus fields that are difficult to access, providing a crucial food source for grizzlies.
A new cancer drug has shown promising results in a mesothelioma trial, controlling disease progression in 67% of patients. The drug targets the cancer's energy system by inhibiting a specific enzyme, causing oxidative stress that kills tumor cells.
Researchers at Terasaki Institute develop a wireless dual-compartment biochemical monitoring platform for real-time tracking of key biomarkers in perfusion fluid and bile during normothermic machine perfusion. The study shows improved interpretation of post-transplant outcomes with combined bile and perfusate data.
A team of astronomers used the James Webb Space Telescope to observe gaseous filaments connecting a galaxy's hot atmosphere to its central supermassive black hole. The observations showed that gas flowed along these filaments and poured into a spinning disk, which feeds the SMBH.
A team of researchers from the University of Cambridge and UC Santa Barbara developed 'adversarial' mathematical systems to map out where AI prediction breaks down. They identified two main reasons why machine learning fails: algorithmic limitations and hidden patterns in complex systems.
Researchers propose using the glucose ketone index (GKI) to track metabolic health in non-communicable diseases, which cause three in four deaths worldwide. The GKI measures blood glucose and ketones and may indicate metabolic state, assess long-term nutritional adherence, and support mitochondrial function improvement.
A European energy system model determines that a uniform benchmark for vehicle charging infrastructure is not optimal, as the cost-optimal level varies by country. Customized targets for EU member states can unlock benefits through smart charging technologies like V1G and V2G.
A novel, two-sided dressing made from sustainable polymers has been developed to deliver antibiotics directly to wounds during critical early stages of infection. The dressing reduces bacterial growth and biofilm formation by over 90%, promoting healing and reducing the risk of treatment failure.
A novel oral vaccine platform using genetically engineered Bifidobacterium could enhance anti-tumor immunity. The results point to potential biomarkers that may help identify patients most likely to benefit from this approach.
The KIMS research team developed a technology that precisely controls the dispersion of PTFE nanoparticles, enabling simultaneous enhancement of hardness, low-friction performance, and wear resistance in silver coatings. This results in a coating that is simultaneously harder, smoother, and more resistant to wear.
A recent clinical trial found that a combination of THC and CBD significantly reduced agitation in people with late-stage dementia. The study, which enrolled 120 participants, showed a 6.27-point reduction in mean agitation scores after 2 weeks and a sustained reduction at 12 weeks.
Researchers at the University of Waterloo have developed a digital manufacturing platform to create patient-specific contact lenses in under 20 minutes. The innovative technology uses custom lens design software and advanced 3D printing combined with a new hydrophilic silicone material, providing precise fit and optical clarity.