A study finds that dementia with Lewy bodies preferentially affects certain brain regions, including those with genes linked to mitochondrial function and synapses. These regions show distinctive patterns of serotonin, dopamine, and GABA receptors, suggesting a potential target for new treatments.
A team of neuroscientists highlights the distinction between intelligence and consciousness, warning against confusing AI systems with human-like emotions and experiences. Decades of research support their argument, citing examples like blindsight, which demonstrates intelligent behavior without conscious experience.
The European Extremely Large Telescope (ELT) will be the most powerful optical and infrared telescope ever built, enabling unprecedented observations of exoplanets and galaxies. Canadian astronomers will gain guaranteed access to the telescope through a $11.3M grant, supporting the development of the ANDES instrument.
A new longitudinal study from Université de Montréal finds that three simple movement habits in toddlerhood significantly predict a more physically active lifestyle in adolescence. Active play with parents, limited screen time, and sufficient sleep are key predictors of later physical activity levels.
A new study identifies profiles of adults at low risk of cannabis use disorder, emphasizing the importance of socio-demographic and lifestyle factors. The research highlights that lower-risk users resemble non-users more than higher-risk users, with distinct characteristics including female sex, education level, and mental health.
SLAMF6 is a molecule on the surface of immune cells that prevents T cells from effectively attacking tumours. Researchers have developed new monoclonal antibodies that prevent SLAMF6 from interacting with itself, potentially offering an option for patients who no longer respond to PD1 or PDL1 treatments.
A large-scale study reveals that generative AI models have reached the threshold of average human creativity, but the most creative individuals still outperform even the best AI systems. The study also highlights the importance of human guidance and parameterization in modulating AI creativity.
A new study by researchers in Canada and Italy suggests that young adolescents who participated in organized sports between ages 6 and 10 are less likely to defy authority figures. The study found that structured extracurricular activities can promote behavioral resilience and reduce the burden of disruptive behavior disorders.
A new study reveals limited data on cognition in individuals with comorbid personality disorder and schizophrenia, leading to unfavourable outcomes. The researchers emphasize the need for further investigation into adapting treatments to support functional recovery.
A new study explores the tool-making skills of immature chimps, finding that nearly half of their uses were atypical and innovative, with most deviating from adult norms. The research suggests that children's creative exploration and social support may drive cultural innovation and complexity.
A large international study reveals that women with a precursor condition to Parkinson's disease exhibit significantly less brain atrophy compared to men. The research suggests that estrogens may play a crucial role in protecting the brain from neurodegeneration.
Researchers developed DNA-based signaling cascades to report and quantify molecule concentrations in blood, enabling point-of-care devices for optimizing treatment. The breakthrough aids efforts to build affordable and portable devices for monitoring medication levels at home.
Researchers found that patients with a lower DTI-ALPS index in the left hemisphere of the brain were more likely to develop Parkinson’s disease, while those with higher levels of free water in the basal nucleus of Meynert were eight times more likely to convert to dementia with Lewy bodies
A team of researchers has discovered a fifth planet in the L 98-59 planetary system, confirming its habitable zone and potential for liquid water. The planets' sizes and masses have been determined with unprecedented precision using data from space telescopes and high-precision instruments.
Astronomers have detected a vast cloud of energetic particles surrounding one of the most distant galaxy clusters ever observed. This discovery reveals that entire galaxy clusters were immersed in high-energy particles for most of their existence.
A recent study found that caffeine increases brain signal complexity and enhances criticality during sleep, with effects more pronounced in young adults. This can lead to a state where the brain is neither fully awake nor relaxed, potentially interfering with restful recovery.
Researchers at the University of Montreal have found that guinea pigs can serve as a reliable and robust small animal model to study human preimplantation development. The study provides new insights into the development of healthy embryos and fetuses, which could lead to improved fertility treatments and reproductive technologies.
Researchers used large language models to analyze healthcare records of over 1,000 children with suspected autism, finding that current criteria prioritize socialization skills and not enough on interests and natural behaviors. The study suggests revising the criteria to focus more on repetitive behaviors and special interests.
Researchers discovered reflective clouds on the western hemisphere of LTT 9779 b, a rare 'ultra-hot Neptune,' creating a striking contrast to its hotter eastern side. The team's findings reveal a delicate balance between intense heat from the star and the planet's ability to redistribute energy.
A six-week stress management program, O'stress, has been shown to improve the emotional health of seniors by increasing problem-solving strategies and reducing anxiety. The program also addresses emotional contagion, a significant factor in psychological distress among seniors.
A new study found that early exposure to violent TV content in childhood is associated with increased risk of antisocial behavior in teenagers, especially boys. The study, led by Professor Linda Pagani, followed over 1,900 children from ages 3.5 to 15 and found that boys who watched more violent TV content had higher rates of aggressiv...
A cluster randomized trial involving 31 Canadian high schools and 3,800 students found that delivering personality-targeted brief cognitive behavioral interventions to students in the 7th grade reduced risk for substance use disorders by the end of high school. The intervention was associated with a 23%-80% reduced odds of SUD compared...
Researchers at Université de Montréal successfully recreated two distinct mechanisms that can program the activation and deactivation rates of nanomachines in living organisms across multiple timescales. This breakthrough suggests how engineers can exploit natural processes to improve nanomedicine and other technologies.
Allophone children who attended preschool services show improved cognitive development, social emotional skills, and communication abilities compared to those who did not. Preschool education is a key factor in bridging the language gap for these children.
A study found that seniors vulnerable to emotional contagion are 8.5-10 times more likely to experience anxiety or anxious depression than less vulnerable individuals. Researchers analyzed data from 170 adults aged 55+, exploring the relationship between emotional contagion and psychological distress.
A study led by Graciela Pineyro and Tomas Paus found that cannabis use in adolescence can lead to thinning of the cerebral cortex, affecting communication between neurons. The researchers used a combination of methods to demonstrate THC's impact on brain cells and identified genes associated with cortical thinning.
Scientists have identified a novel molecular mechanism underlying brain cell communication, regulating excitatory synapse maturation and contributing to anxiety disorders. The study reveals the TrkC-PTPσ complex governs synaptic protein phosphorylation, leading to abnormal synapse organization and behavioral defects in mice.
A new study found that the effects of alcohol exposure on an embryo prior to implantation can be detected in the late-gestation placenta. The research revealed significant molecular changes in the placenta, including DNA methylation alterations that could serve as a molecular signature for detecting alcohol exposure.
Researchers have made a promising breakthrough in understanding the origins of mirror movements disorder by identifying the cellular mechanism behind the condition. A defect in axon guidance is revealed to be the underlying cause of the disorder, which can lead to difficulties in performing tasks requiring left-right coordination.
Veterinary scientists at Université de Montréal have created a way to scan the brains of cats while they're awake by concealing electrodes in crocheted wool caps. This new technique uses electroencephalograms (EEGs) and can help alleviate chronic pain in cats.
A major international study found that 3% of adults have a real problem with pornography, with men more likely to experience issues than women. The research also highlights the need for support and understanding among those affected by problematic porn use.
Researchers used the James Webb Space Telescope to analyze the atmospheric composition of HAT-P-18 b, detecting water vapour and carbon dioxide. They also found a cloud deck that mutes the signals of many molecules, and their findings suggest the star's surface is covered by dark spots. The study highlights the importance of considerin...
Researchers at Université de Montréal's Department of Chemistry have created a new fluorogenic probe to study interactions between sugars and proteins, which are essential to life. The probe can visualize these interactions using fluorescence, providing a valuable tool for studying biological processes critical to human health.
Researchers used the James Webb Space Telescope to observe TRAPPIST-1 b, finding strong stellar contamination in its transmission spectra. The team discovered that stellar activity can create 'ghost signals' that may fool observers into thinking they have detected specific molecules in the exoplanet's atmosphere.
A meta-analysis of 71 studies on autism suggests that people with autism may acquire language differently than neurotypical individuals. While interventions aimed at promoting social communication showed no significant language gains, some children with autism learn language without social interaction, such as through digital tablets. ...
Researchers successfully recreated and mathematically validated two molecular languages at the origin of life, opening doors for nanotechnology development. They designed a programmable antibody sensor using multivalency, which detects antibodies over different concentration ranges.
Researchers at the University of Montreal found that movement circuits in mice brains are insensitive to dopamine levels, contradicting initial hypotheses. This discovery could lead to new approaches to reduce Parkinson's disease symptoms by identifying mechanisms involved in dopamine secretion.
A new study shows that newborn screening for severe combined immunodeficiency disease (SCID) has significantly increased the survival rate of children after bone marrow transplantation from 73% to 87%. Children diagnosed at birth have a 92.5% survival rate without infection, while those diagnosed later have lower rates.
Researchers discovered the abundance of rock-forming elements in WASP-76 b's atmosphere, which matches its host star and our own Sun closely. The team found that certain elements are depleted due to temperature conditions, providing insight into the sensitivity of giant planet atmospheres.
Researchers used the NIRISS instrument on the James Webb Space Telescope to create a temperature map of the exoplanet WASP-18 b, revealing a huge temperature change from day to night sides. Water vapor was also detected in the atmosphere at various elevations.
Astronomers have discovered a new temperate exoplanet, LP 791-18 d, with properties similar to those of Earth. The planet is believed to be covered in volcanoes due to tidal heating, which causes heat to build up in its interior.
Researchers discovered that sensory signals are underrepresented in cortical pyramidal neurons of people with Fragile X syndrome (FXS), a common cause of autism. This finding could lead to new therapeutic strategies and improved perception of sensory signals.
A Canadian-led research team has discovered how the protein PCSK9 degrades LDL receptors, leading to increased cholesterol levels. HLA-C plays a critical role in this process, which could lead to new treatments for cardiovascular diseases and certain cancers.
A Canadian study reveals that obesity reprograms immune system cells, making them destructive to the eye as it ages. The research sheds light on the molecular mechanism behind AMD and may lead to tailored treatments in the future.
Researchers at the University of Montreal discovered a key mechanism in muscle regeneration, enabling targeted therapies for diseases like muscular dystrophy. By biasing the conformation of a protein called ELMO2, they improved muscle fusion and regeneration in mouse models.
Researchers have identified two exoplanets, Kepler-138c and d, as 'water worlds,' with a significant fraction of their volume likely composed of water. The planets are about one and a half times the size of Earth and have much lower densities than our planet.
Caulobacter crescentus uses a toxin-antitoxin system to regulate programmed cell death in response to oxygen limitation, releasing DNA that promotes sibling dispersion. This mechanism helps maintain biofilm balance and prevents overcrowding.
A research team used photogrammetry to build 3D models of flowers from two-dimensional images, gaining new insights into the shape and color of flowers. The technique allows for detailed study of flowers' morphology and colors, which act like magnets to attract pollinators.
A new study led by Linda Pagani found that watching violent TV during the preschool years can lead to later risks of psychological and academic impairment. Exposure to typical violent screen content at a critical time in brain development can predict later psychological distress and academic risks.
Researchers have designed DNA-based transporters that can deliver precise concentrations of drugs, potentially improving cancer treatment. These nanotransporters can also be programmed to prolong the effect of a drug and minimize its dosage, reducing side effects.