A molecular system called PrrAB helps the TB bacterium generate energy and breathe, making it a promising target for new treatments. Researchers have identified an experimental compound DAT-48 that kills several strains of TB, including clinical ones, with potential synergy when combined with existing drugs.
Researchers discovered a dual mechanism by which Oroxylin A inhibits SIRT7, reprogramming HSCs through PRMT5 succinylation-driven senescence and ecto-calreticulin-dependent NK cell immune clearance. This approach provides a promising candidate for anti-fibrotic therapy.
A new study found that public greenspaces are lacking in many American communities, with some groups facing significant barriers to access. The research highlights the need for more inclusive park planning and distribution to ensure equal benefits for all residents.
Researchers tracked pine plantations in North Florida for 27 years to identify site preparation strategies with sustained benefits. Two-pass treatments consistently outperformed simpler methods, especially when combined with herbicide applications.
Chronic wounds like diabetic foot ulcers and pressure ulcers are driven by persistent inflammation and immune dysregulation. Emerging immunomodulatory strategies aim to restore immune balance and promote healing.
Researchers found that magnetic mitohormesis, a non-invasive treatment, can activate metabolic pathways triggered by exercise, improving glucose control without physical strain. Patients with excess belly fat experienced significant improvements in blood glucose control and HbA1c levels.
SourceSingHealth·JournalJournal of Clinical Medicine·TypeRandomized controlled/clinical trial·DateOct 30, 2025
A Chinese research team has identified a rare natural allele in wild soybeans that increases seed protein content and was lost during domestication. The found allele, PC08 Ins, boosts gene expression, raises ABA levels, and promotes storage protein accumulation.
Researchers developed a new model to simulate and project China's agricultural non-CO2 greenhouse gas emissions, identifying priority regions and subsectors for mitigation. The study found that current mitigation efforts achieve only 26-45% of the total technical potential, with significant room for improvement.
A Griffith University study published in Nature Mental Health found that integrating nature-based therapies into clinical healthcare could address global declines in mental health. Nature experiences designed to improve mental health are not yet incorporated in regulated clinical healthcare, but embedding nature therapy into clinical h...
A major new synthesis of global evidence reveals that restoring forests can actually increase water availability, particularly during critical dry seasons. The research highlights the importance of prioritizing dry-season flow recovery in large-scale forest landscape restoration.
Researchers designed a NiO@NiAlO catalyst with a surrounded structure modified by MgO, achieving high activity for near-equilibrium conversion. The obtained catalyst maintained stability for over 50 hours without coking at 600°C.
Researchers developed a new photocatalytic material combining cobalt, reduced graphene oxide and perylene tetracarboxylic acid for efficient water oxidation. The heterojunction design shows improved charge separation and catalytic activity.
Researchers from the University of Melbourne found high levels of synthetic PFAS in possums from the greater Melbourne region, linked to serious health effects. The study is the first to investigate PFAS levels in Australian marsupials and highlights broad contamination of Australian ecosystems.
A new study by Alana Rojewski and Katherine Sterba aims to improve access to tobacco cessation treatments for people living with HIV who smoke. The ENHANCE-TTS program will train pharmacists as tobacco treatment specialists and tailor-design programs for each clinic, taking into consideration the unique needs of the local population.
Researchers have discovered a way to increase the energy state of iron in materials, enabling the creation of higher-voltage batteries. The breakthrough could also aid the development of superconductors and magnetism applications.
The BrainHealthy competition offers real-world experience to talented young brain health researchers. The contest aims to advance new studies on age-related brain changes, brain health biomarkers, and Alzheimer's disease.
Researchers at the Medical University of South Carolina have identified a previously unknown hub in the brain's lymphatic drainage system, which helps remove waste from the brain. The study provides evidence of a slow-moving fluid flow through true lymphatic vessels, rather than blood vessels.
Three UCSB physicists, Sebastian Streichan, David Patterson, and Andrea Young, are among the selected researchers receiving funding to investigate the physics of tissue morphogenesis, chiral molecules, and quantum materials. This award aims to unlock new insights into fundamental research in experimental physics.
A study published in Science reveals that the enteric nervous system (ENS) plays a key role in maintaining gut balance and protecting against harm. Researchers mapped ENS responses to different conditions, including allergies and parasitic infections, using mouse models with fluorescent tagging systems.
Research discovered that meerkat's social group membership has the greatest influence on their gut microbiome, even more than age, sex, or environmental conditions. The study found that social interactions lead to the sharing of beneficial gut bacteria, which is vital for an animal's immunity and overall fitness.
Researchers found that combining organic manure with synthetic fertilizer increases soil organic carbon and total nitrogen, leading to better fertility and improved crop performance. The integrated approach also produced lower nitrous oxide emissions by stimulating microbes that can break down N2O.
A UAlbany researcher is leading a $1.2 million NSF project to integrate climate records from stalagmites, corals, lake sediments, and tree rings to understand past changes in monsoon rainfall patterns. The study aims to improve decadal predictions and risk management for societies vulnerable to climate change.
A recent study found that access to veterinary care is generally good in the US, but rural areas experience significant delays and increased travel distances. The study used a secret shopper survey approach to assess appointment availability and wait times across six states.
A team led by Lu Li has made a groundbreaking discovery in the field of materials science, finding that quantum oscillations arise from the bulk of insulators rather than just their surface. This new understanding challenges the current perception of material behavior and opens up new avenues for research and potential applications.
Researchers have developed a new molten salt technique that restores the structure and performance of used high-nickel cathode materials, allowing for more efficient battery recycling. The approach, published in Energy & Environment Nexus, regenerates the material itself so it can be reused in new batteries.
Researchers at Carnegie Mellon University found that large language models with reason possess selfish tendencies and do not cooperate well. The stronger an LLM's reasoning skills, the less it cooperates. This self-seeking behavior may negatively impact human cooperation in business, education, and government.
The Lundquist Institute has been awarded $9 million by the California Institute for Regenerative Medicine (CIRM) to establish a Community Center of Excellence for Regenerative Medicine. This center will expand access to cutting-edge regenerative therapies and create skilled healthcare professionals in underserved communities.
Researchers at the University of California San Diego found that oscillators operating at similar frequencies lock onto each other in succession, creating a staircase effect in the gut. This new mathematical solution answers two longstanding biological questions, shedding light on how food moves through the digestive tract and is churned.
The study found that men, Black patients, and those living in low socioeconomic areas were disproportionately affected by the increased amputation rates. The authors emphasize the need for aggressive prevention, early diagnosis, and intensive risk factor management to address the growing burden of diabetes and PAD.
Researchers mapped functional impact of over 17,000 genetic variants associated with premature atherosclerotic heart disease. The new variant impact scores have the potential to increase diagnoses for unclassified variants by a factor of 10.
A new digital clinical trial is testing a repurposed drug, tirzepatide, to provide relief from long COVID symptoms. The study aims to enroll 1,000 participants and explore the effect of tirzepatide on long COVID over one year.
Children born to mothers infected with COVID-19 while pregnant are at a higher risk of developing developmental delays, including speech difficulties and autism. The study found that males were more susceptible to adverse outcomes compared to females.
Researchers found that a structurally modified version of the drug florfenicol exploits drug resistance mechanisms in Mycobacterium abscessus to amplify its effect, perpetually. This approach presents a potentially safer and more effective way to treat certain antibiotic-resistant infections, minimizing host mitochondrial toxicity and ...
Scientists have developed the world's first lab-produced, recombinant snakebite antivenom that protects against many African deadly snakes and outperforms existing antivenoms. The new formulation provides high protection against death and severe tissue damage caused by 17 different elapid snakes.
This study found 32 immune cell phenotypes associated with epilepsy risk, including B cells and regulatory T cells. Inflammatory proteins also played a role, with some increasing and others decreasing the risk of epilepsy.
The article argues that a universal 30 mL/kg fluid bolus is no longer appropriate and instead calls for a balanced, individualized approach to fluid management in septic shock. This approach considers the patient's comorbidities, infection source, and estimated fluid losses, and guides management by frequent reassessment.
A recent study found that preserving just one centimeter of corpus callosum fibers is enough to maintain information exchange between the two brain hemispheres, preventing neurological symptoms. The research challenged long-held assumptions about the relationships between brain structure and function.
The journal is launching a new section to popularize evidence-based strategic planning in digital health and provide comprehensive guidelines for its application. Papers can explore topics such as strategic planning frameworks, case studies of successful implementations, and stakeholder engagement.
International physics experiments suggest neutrinos may have tipped the balance in favor of matter over antimatter. Neutrinos' unique oscillation behavior could have led to an imbalance in the early universe.
Dr. Oren Moscovitz and his team aim to develop an innovative treatment for triple negative breast cancer using engineered antibodies with high specificity. The new grant will test the safety of these antibodies in humans.
Researchers at Aalto University have developed a promising new treatment approach for dry age-related macular degeneration (AMD), which can potentially stop the disease's progression. The novel method uses heat and near-infrared light to trigger healing responses at a cellular level, strengthening protective mechanisms of affected cells.
The Global Virus Network welcomes three new Centers of Excellence in the US, Brazil, and Canada, strengthening its presence across the Americas. The new centers will focus on combating viral threats from HIV and arboviruses to emerging pathogens and future pandemic agents.
Researchers developed a new spectral shaper technology that can precisely control 10,000 individual lines of light, improving signal fidelity and enabling faster data transfer in various fields. This advancement could aid in the detection of Earth-like planets by making tiny stellar wobbles easier to measure.
Researchers developed a landmark model predicting 14 complications in diabetes patients over 15 years, showing early treatment makes a difference. The Multiethnic Type 2 Diabetes Outcomes Model for the U.S. (DOMUS) uses real-world patient data from Kaiser Permanente.
A new study explores the tool-making skills of immature chimps, finding that nearly half of their uses were atypical and innovative, with most deviating from adult norms. The research suggests that children's creative exploration and social support may drive cultural innovation and complexity.
A new framework harnesses generative AI to create personalized mental health treatment plans, addressing common barriers and improving outcomes for diverse individuals. The study uses a simulated client to explore pathways to mental health care and demographic disparities.
Research found that sharing happy moments with a partner can lower cortisol levels in older adults, even if they're not satisfied with their relationship. The study suggests co-experiencing positive emotions may help the body stay calmer over time.
Researchers develop distribution-type membrane reactors for efficient carbon dioxide methanation. The study demonstrates the advantages of this approach in controlling reaction rates and temperature profiles. High thermal conductivity membranes produce more methane with selectivity, and their use can accelerate a carbon-neutral society.
A rare case of a mucinous vulvar cyst was reported, which resembled a benign lipoma and caused lower abdominal and back pain. The cyst was surgically removed and confirmed to be non-malignant. The case underscores the importance of careful clinical examination in reproductive-age women presenting with vulvar masses.
A study published in the Archives of Sexual Behavior found that bisexual and homosexual men are more jealous of emotional infidelity, similar to women. This contradicts previous assumptions that men are primarily jealous of sexual infidelity.
Researchers use ultraviolet light to create angstrom-sized channels in polymer membranes, allowing for precise separation of ions and small molecules. The technique enables sieving of monovalent ions from multivalent ions, with adjustable channel sizes.
A study found that many US adults believe alcohol has no effect on cancer risk, despite growing evidence linking alcohol use to an increased risk of various cancers. This persistent misbelief contributes to the rising burden of alcohol-related cancers in the country.
Researchers developed a tool to measure food production's impact on species survival, finding that eating beef and lamb has the biggest effect on extinctions. Switching to vegetarian diets could halve biodiversity impact in the UK.
Researchers developed wearable components for cyborg insects, preserving natural functions and enabling stable neural responses. The design uses multimaterial 3D printing and surface stimulators to control motion and navigation.
A new AI model has successfully identified four battery electrolytes that rival state-of-the-art electrolytes in performance, starting with a minimal dataset of 58 data points. The team used an active learning approach, incorporating experiments as outputs to refine the model's predictions and verify the findings.
Research reveals that microorganisms in ocean hypoxic zones convert nitrate into nitrous oxide to generate energy, producing this climate-damaging gas. The study's findings suggest that organic material in these zones increases the oxygen tolerance of bacteria, allowing for more regions of nitrous oxide production.
The Annenberg Public Policy Center survey finds that most American adults are unclear about the dangers of measles and the value of vaccination. The survey also shows a decline in support for MMR vaccination among parents, from 90% in November 2024 to 82% in August 2025.
Researchers at KAIST have created a new manufacturing method for high-performance green hydrogen electrolysis cells, reducing production time from six hours to just ten minutes. The technique uses microwaves to heat ceramic powders uniformly, achieving stable electrolyte formation at lower temperatures.
A new study suggests that supplementing with BCAAs alongside an exercise program may help reduce fatigue, improve strength, and ease symptoms of depression for older adults. The research found notable improvements in participants who combined a BCAA supplement with an eight-week exercise program.
Scientists at Moffitt Cancer Center identify distinct approaches to combat drug resistance in non-small cell lung cancer, targeting RAS and CDK12/13 pathways. Combining therapies delays or prevents resistance, extending treatment response.
A new tool, WatDAT, measures vision equally precisely in younger toddlers by asking them to point out different shapes at progressively smaller sizes. This test can lead to earlier detection and treatment of vision problems in children under three, such as amblyopia or farsightedness.
A new study on the March 2025 Mandalay earthquake reveals that an unusually thick, low-velocity fault zone enabled a supershear rupture to sustain for hundreds of kilometers. This behavior often occurs on simple, straight faults like the San Andreas and Sagaing faults.
A study of Brazilian fishers revealed that synchronization of heart rates during fishing is mainly shaped by internal group dynamics, with no significant impact from external influences. The researchers found a negative association between high synchronized behavior and the amount of fish caught.
Researchers developed spherical carbon superstructures with hydrogen-bond guidance to enhance energy storage performance in zinc hybrid capacitors. The work highlights the importance of interfacial engineering and hierarchical porosity for advancing high-energy energy storage technologies.
The American Institute of Physics has awarded PhET Interactive Simulations a $25,000 grant to develop a professional learning course and community for high school physics teachers. The award aims to improve physics education in the US by raising interest and boosting quality.
Researchers Prof Axel Cleeremans, Prof Anil Seth, and Prof Liad Mudrik warn that advances in AI and neurotechnology are outpacing our understanding of consciousness. They emphasize the need for theory-driven research and innovative methods to advance consciousness science.
A small phase I study has shown that directly injecting an immune-activating compound into prostate tumors before surgery appears safe and may help the immune system recognize and attack cancer cells. The therapy, called poly-ICLC, was well tolerated and appeared to jump-start immune activity.
Recent advances in systemic light chain (AL) amyloidosis diagnosis and treatment highlight the integration of novel biomarkers, imaging modalities, and targeted therapies. Key findings include improved hematologic and organ responses with daratumumab-based regimens and emerging therapies like BCMA-targeting bispecific antibodies.
The Aedes aegypti Mosquito Cell Atlas provides comprehensive cellular-level resolution of gene expression in every tissue, from antennae to legs. This atlas has yielded new insights into the genetic secrets of Aedes aegypti, including novel cell types and subtle differences between male and female mosquitoes.
A new fossil discovery confirms Nanotyrannus as a distinct species from Tyrannosaurus rex, challenging decades of research on T. rex growth. The fossil reveals that Nanotyrannus was physically mature at age 20 and had distinct skeletal features incompatible with T. rex.
A new $4 million grant will support the establishment of a health economics research facility to evaluate and compare the economic value of available interventions in the criminal-legal system. The researchers aim to develop tools and resources for policymakers to identify strategic investments in substance use disorder care.
A new study published in Science finds CTE shares genetic similarities with Alzheimer's disease, including DNA damage and tau protein buildup in the brain. Researchers used single-cell genome sequencing to identify somatic mutations in neurons from patients with CTE, revealing abnormal patterns of damage similar to those seen in AD.
Researchers at WashU Medicine discovered central routes that deadly viruses take to invade human cells, designing decoy molecules to block infections. The studies set the stage for developing new strategies for yellow fever and tick-borne encephalitis viruses.
Researchers have discovered that extended periods of high stress in wheat crops can lead to iron deficiency and stunted growth. By reducing iron deficiency with a synthetic organic molecule called PDMA, plants are able to improve photosynthesis and biomass under heat stress conditions.
The Omnia bionic leg, developed by the Italian Institute of Technology, won the Cybathlon 2024 leg prosthesis race with its semipowered knee and ankle system. Andrea Modica, a transfemoral amputee and pilot of the device, successfully completed 9 out of 10 tasks in just 2 minutes and 57 seconds.
Researchers developed a prognostic model using machine learning to predict suicide risk in depression patients. The study found that clinical features and biochemical biomarkers, such as TSH levels, contributed significantly to the model's accuracy, achieving an 82% success rate.
A Rutgers Health analysis found that discrimination, stigma and chronic stress contribute to increased anxiety, depression, PTSD & substance use among young sexual minority men. Chronic stress is associated with substance use, while experiences of discrimination are linked to social withdrawal from nightlife settings.
Researchers at Sanford Burnham Prebys have developed a new method to generate more and potent skeletal muscle progenitor cells. The study found that blocking the activity of Janus kinase 2 (JAK2) yields a twofold increase in cell yield, while also delivering more mature and effective cells for regenerative medicine treatment.
Researchers studied beaver ponds' effect on groundwater recharge, finding a 10-fold increase in recharging water. They also explored evapotranspiration and found it can reduce recharge in certain soil structures. The study highlights the need for comprehensive analysis of beaver-induced changes to understand their impact on ecosystems.
A new resource identifies genetic variants associated with elevated 'bad' cholesterol, a major contributor to heart disease. Clinicians can now predict patient risk for heart attacks and strokes, allowing for prevention and early treatment.
A cohort study found that poor olfaction is associated with a higher risk of coronary heart disease in older adults. The study suggests that assessing olfaction may be an important factor in identifying individuals at risk for cardiovascular disease.
A new collaboration between Rice University and Baylor College of Medicine aims to predict kidney injury sooner after heart surgery, potentially reducing hospital stays and mortality. The project uses artificial intelligence to analyze vast amounts of data from thousands of cardiac surgery patients.
Experimental tests demonstrate that interactions between magma oceans and primitive atmospheres during early years can produce significant amounts of water. This process has major implications for the physical and chemical properties of planets' interiors, with potential effects on core development and atmospheric composition.
Researchers developed advanced imaging strategies using intelligent micro/nanomotors, enabling enhanced detection sensitivity and real-time tracking of subcellular events. The proposed approach integrates MNMs as dynamic contrast agents for multimodal diagnostics, providing a theoretical framework for bioimaging technologies.
A new study from UBC Okanagan has mathematically proven that the fundamental nature of reality operates in a way that no computer could simulate. The researchers demonstrate that a complete and consistent description of everything requires non-algorithmic understanding, which is beyond algorithmic computation.
Researchers developed an AI-driven framework to predict which plant species are most likely to become invasive before they even arrive in a new location. The methodology combines decades of ecological data with machine learning methods to identify high-risk species.
This study analyzed global publications of EEG-fNIRS synchronization techniques for their diagnostic and therapeutic value in clinical applications. The research identified hotspots, development trends, and future directions in neurology, emphasizing the importance of multimodal technology for disease diagnosis and treatment.
Acute lung injury is characterized by diffuse inflammation and intractable hypoxemia, with N6-methyladenosine methylation playing a crucial role in its pathogenesis. The review synthesizes findings from multiple studies, highlighting the dynamic nature of m6A methylation and its associated proteins.
Researchers from Kyoto University have found that immature oligodendrocyte progenitor cells can switch fate to restore blood flow after stroke. These low-oxygen-conditioned OPCs migrate to the stroke region and survive, promoting new blood vessel formation and partially restoring brain function.
Researchers studied the genetic response of umbrella acacia and splendid thorn acacia to drought stress. The study found that umbrella acacias prioritize continued growth over water conservation when water is scarce, using up all accessible water to survive severe droughts. In contrast, splendid thorn acacias invest in water conservati...
Huimin Zhang, a UC Riverside assistant professor, has received a $150,000 grant to study the role of HELIOS in epigenetic regulation of T cell aging and TFH cell differentiation. Her research aims to understand how aging affects the immune system and develop new vaccines and therapies to restore immune vitality in older adults.
EULAR has established new points to consider and consensus definitions for managing difficult-to-treat psoriatic arthritis, aiming to improve treatment options and care for patients. The guidelines focus on identifying the biology behind treatment non-response and promote personalized treatment approaches.
Reactive oxygen species (ROS) homeostasis is essential for cellular survival and physiological functions. The review discusses its biological significance, potential clinical applications, and regulatory mechanisms underlying ROS homeostasis. Dysregulation of ROS homeostasis is a common pathogenic mechanism driving disease development.
A study reveals a sustained decrease in marine virus abundance in the northwestern Mediterranean over two decades, coinciding with rising water temperatures, nutrient loss, and phytoplankton biomass decline. This oligotrophication process may accelerate ecosystem instability and affect fisheries-dependent societies.
A new study found that ultra-processed food consumption is associated with smaller but significant declines in physical function, including slower gait speed and weaker grip strength in men. Limiting UPF intake may be crucial for preserving physical function and supporting healthy aging.
A policy-specific assessment framework evaluates integrated effects of emission control policies on greenhouse gas mitigation, air quality improvement, and public health protection. China's on-road transportation policies have achieved remarkable progress but face weakening synergies, underscoring the need for deep structural transitions.
In Oman, a significant decline in birth rates since the 1970s is observed due to shifting marriage practices and gender roles. The research reveals nuanced changes in values surrounding birth control and family planning over several generations.
Researchers have uncovered a mechanism by which BRCA2-deficient tumors develop resistance to chemotherapy. The discovery sheds new light on the role of proteins BRCA2 and FIGNL1, revealing their unexpected function in maintaining DNA repair mechanisms.
Researchers used global environmental DNA (eDNA) surveys to map marine fish species' geographic ranges. These findings highlight current biases in conservation efforts and ecological models.
A new study reveals that laws restricting pain clinics, or 'pill mills,' where opioids were often prescribed, reduced risky opioid use by 5 percent. Enacting such laws near the onset of the crisis in the 1990s could have reduced risky use by 30 percent over time.
A new Swedish study found that breast cancer risk varies depending on the type of hormone in hormonal contraceptives. Desogestrel was linked to a higher risk, while levonorgestrel products showed a lower risk, indicating that some contraceptives may be safer options for women with a higher baseline risk.
The bioactive components of Scleromitrion diffusum exhibit potent anticancer activity by inhibiting proliferation, inducing apoptosis, and suppressing metastasis. Its multi-compound, multi-pathway approach targets several critical pathways in gastric cancer pathogenesis.
Researchers at Graz University of Technology have developed a new approach to understand protein function and stability, identifying amino acids crucial for both with high accuracy. The FSA method combines machine-learning-generated sequences with natural sequences, revealing functional and structural significance of amino acids.
A multidisciplinary research team discovered that liver alterations associated with metabolic dysfunction can cause cognitive and neurological impairments. The effects were reversed by a therapy targeting the liver, establishing a 'liver-brain axis'. This finding opens up new therapeutic avenues for treating metabolic liver disease.
Researchers have developed an AI-driven facial recognition system called AcroFace that can detect acromegaly by analyzing facial photographs. The system achieved a success rate of 93% in a preliminary trial, outperforming previous attempts. Early detection could lead to timely treatment and improved outcomes for patients with this rare...
Researchers developed a photothermal catalyst, Li0.51Mn2O4, to upgrade spent lithium manganate oxides and waste PET into highly efficient recyclable materials. The study achieved high conversion rates and reduced fossil resource consumption by up to 77% compared to traditional thermal catalysis.
A new study published in Science provides evidence that chimpanzees can change their minds based on the strength of available evidence, a key feature of rational thought. Researchers found that chimps frequently switched their choices in response to stronger clues, aligning with rational strategies of belief revision.
A study has identified over 240 scientific publications with potentially problematic images, casting doubt on the validity of these studies. The findings highlight the need for journals and publishers to investigate image-related issues carefully to ensure the trustworthiness of animal-based research in this field.
The Politecnico di Milano has created an online application to select the most effective AI models for creating 3D images of individual organs or lesions. This tool makes treatment more accurate and reliable, saving professionals time and effort.
Researchers propose a 3D quantum anomalous Hall effect in Weyl semimetals, revealing unique boundary states and transport properties. The discovery completes the Hall effect family in three dimensions, holding promise for applications in low-power electronics and programmable devices.
A recent study investigated antenatal anxiety among first-trimester pregnant women in China, revealing a prevalence of 2.54%. Risk factors identified include young age, economic hardship, and lack of social support. The authors recommend targeting these vulnerable groups with early anxiety screening and targeted support.
Researchers used lipid biomarker analyses to study survival strategies of microorganisms in extreme deep-sea ecosystems. They found that methane- and sulfate-metabolizing microbes can thrive in environments with high pH values and low organic carbon concentrations.
The JAMA Summit on Firearm Violence aims to chart a roadmap toward reducing firearm violence, injuries, and deaths in the US. The summit emphasizes five essential actions: prioritizing community safety, supporting evidence-based interventions, and addressing upstream conditions that fuel gun violence.
Researchers from NYU Langone Health have made a significant discovery about how the brain forms and recalls memories. The study shows that activity in signaling pathways connecting two brain regions, the entorhinal cortex and the CA3 region of the hippocampus, help mice encode in brain circuitry maps of places.
Citizens' smartphones can be used to create highly detailed site amplification maps, providing critical input for seismic hazard assessment and supporting earthquake emergency response. The new approach, based on the Earthquake Network initiative, aggregates thousands of measurements to yield reliable high-resolution amplification maps.
Researchers at UTA are exploring how guided cognitive training can improve brain performance, particularly in navigation and memory. The study found that functional brain changes support behavioral differences, rather than increased brain volume.
A study has identified priority areas to reduce macaw deaths from electrocution in Brazil. Modifying 10% of high-risk poles could prevent 80% of these deaths, according to the research.
A recent study published in Science reveals that Myanmar's Sagaing Fault produced a supershear earthquake with speeds up to five kilometers per second, causing widespread destruction. The researchers attribute this phenomenon to the fault's ideal geometry and contrasting rock properties.
Researchers discovered how neural circuits assemble with precision during development by studying the fruit fly's olfactory system. They found that partner selection occurs on a two-dimensional surface, then along fixed trajectories, and identified key surface proteins mediating attraction and repulsion between neuron types.
Researchers developed a simulation method to model rotating regular black holes, which naturally show time-varying patterns of light and shadow. This breakthrough enables faster exploration of different black hole configurations without requiring delicate tuning.
A novel multichamber magnetic capsule robot has been developed to selectively open specific chambers for targeted liquid sampling or drug release, revolutionizing digestive tract diagnosis and treatment. The robot's modular design allows for flexible adjustment of the number of chambers as demand requires.
Researchers found that baseline Anti-Mullerian Hormone (AMH) levels between 2.1-2.8 ng/ml correspond to 35-42% of live birth rates in women with cancer using fertility preservation. The study aims to improve prediction and standardization for fertility treatments.
Lactate accumulation drives lactylation, a critical post-translational modification promoting tumor proliferation, metastasis, and therapy resistance. Emerging strategies targeting lactate production, transport, and lactylation hold significant anticancer potential.
A new study from researchers at Dell Medical School found that AI-powered tools can improve patient decision-making and outcomes for knee replacement surgery. Patients who used the digital twin tool reported higher decision quality, less regret, and better knee function compared to those who received educational materials alone.
The USF Health Institute for Translational Virology and Innovation advances research on viral diseases, virus-associated cancers, and pandemic pathogens. The institute focuses on understanding the mechanisms of viruses causing tumors and developing comorbidities in HIV patients.
Recent advances in deep learning techniques have overcome limitations in spatial and temporal resolution of BOLD-fMRI. DL models improve image quality through super-resolution reconstruction, automate segmentation, and enhance registration, enabling finer localization of neural activity and more precise brain activity quantification.
Researchers used electron microscopy to investigate ammolite's structural properties, finding that the colors are caused by light reflecting off narrow gaps between aragonite plates. The findings could inform the development of non-fading colored paints.
The American Heart Association's Hearts on the Court Collective aims to raise awareness of cardiovascular disease in women through public service announcements and education. Led by LSU women's basketball coach Kim Mulkey, the collective is committed to empowering fans and student athletes to take charge of their cardiovascular health.
A study found that maintaining moderate physical activity over three decades can significantly reduce digestive system cancer risk. The optimal level of physical activity was around 17 metabolic equivalent task-hours/week, equivalent to 5 hours of brisk walking or 2 hours of running per week.
Researchers at UMass Amherst have developed an app that uses Apple Watch data to monitor sleep stages and predict Alzheimer's disease risk. The app, BIDSleep, collects heart rate data and feeds it into an AI model that accurately identifies sleep stages 71% of the time.
The Mount Sinai Tisch Cancer Center has introduced a real-time data integration tool to automate the transfer of clinical data from its electronic health record system into clinical trial platforms. This technology streamlines data flow, reducing manual transcription time by up to 70% and improving data quality and workforce efficiency.
A new chemotherapeutic agent, LiPyDau, has been developed to tackle drug-resistant cancers. The liposomal formulation delivers the active ingredient directly to tumour cells while minimizing damage to healthy tissues.
A University of Houston researcher identifies a protein that may reduce high ketone levels in diabetic patients, potentially improving health outcomes. The study also shows that the protein promotes muscle ketolysis and running capacity in mice.
A new study analyzing soils across Kansas found that the legacy effects of soil microbes can have significant impacts on plant growth, particularly for native species. Researchers discovered that plants grown with microbes adapted to specific local conditions performed better under drought conditions, suggesting a potential source of g...
Researchers at the University of Surrey have developed a brain-inspired approach to improve artificial neural networks' performance without sacrificing accuracy. The method, called Topographical Sparse Mapping (TSM), rethinks how AI systems are wired by connecting each neuron only to nearby or related ones.
A comprehensive molecular analysis of renal medullary carcinoma identified overexpression of TROP2 and the Hippo pathway in patients. The study found sacituzumab govitecan to result in partial responses and stable disease in heavily pretreated RMC patients.
The RamanProSeq project develops novel optical technology for sequencing individual protein molecules, offering unprecedented accuracy in understanding protein structures and functions. This technology has potential applications in personalized medicine, early disease diagnostics, and drug development.
Researchers have developed bio-hydrovoltaic technology that converts low-grade thermal energy into electricity through dynamic biological processes. This technology offers unique advantages, including self-regulation, biodegradability, and low maintenance costs.
Researchers at MD Anderson Cancer Center identified distinct cellular microenvironments in diffuse large B-cell lymphoma tumors, providing a framework to develop therapies that engage the patient's immune system. Additionally, a study found widespread misbeliefs about the cancer risks of alcohol among Americans, highlighting the need f...
A new study suggests that message-based psychotherapy is as effective as live video therapy for treating depression. The research found that patients improved at similar rates regardless of the format used.
A new study found that more than half of American adults misunderstand the link between alcohol consumption and cancer. Alcohol drinkers are particularly likely to believe drinking has no effect on cancer risk. Correcting these misbeliefs may strengthen adherence to U.S. Surgeon General’s guidelines for lowering cancer risk.
Researchers have identified replication protein A (RPA) as an essential protein for maintaining telomeres, which are protective caps at the ends of chromosomes. This discovery has significant implications for understanding and treating diseases caused by shortened telomeres, such as aplastic anemia and acute myeloid leukemia.
Researchers have developed a new class of artificial muscles that respond to ultrasound, enabling precise movements and wireless control. The technology has vast potential for future medical and technical applications, including drug delivery, cardiac patches, and minimally invasive procedures.
HealthLocator gathers national quality data to compare hospitals based on performance and provide informed care choices. The tool is offered as a free public service by Mayo Clinic, using evidence-based measures to rate over 5,000 U.S. hospitals.
Researchers developed a machine learning technique to analyze plasma emission spectra, accurately identifying valence states and predicting film growth rates. This method uses full-wavelength information and can be used for real-time film deposition control technology.
Scientists will study moisture-driven mechanisms of ice sheet growth during the Miocene Climatic Optimum, a warmer climate period. The team aims to understand how increased moisture transport affects ice accumulation and mitigate sea level rise.
Researchers from Chiba University developed an AI-based spatial framework to identify areas with limited vertical greening, revealing uneven distribution and high-priority zones for improvement. The framework provides a citywide map of vertical greenery, aiming to enhance cooling, biodiversity, and urban resilience.
Researchers at the University of Illinois have developed a process to convert food waste into sustainable aviation fuel that meets industry standards. The process involves hydrothermal liquefaction and refining biocrude oil with hydrogen and catalysts to produce clean jet fuel.
Australian researchers have developed tiny compartments to help supercharge photosynthesis, enabling plants to fix carbon more efficiently. The team engineered encapsulins that can house the enzyme Rubisco in a confined space, allowing for fine-tuning of compatibility for future use in crops.
A new analysis of the PANDA trial found that sertraline contributes to improvements in low mood and suicidal thinking within two weeks of taking the drug. The study also revealed an improvement in emotional symptoms of depression within two weeks, with continued benefits from six weeks to 12 weeks.
A new UCLA Health study found that a child's early gut microbiome may influence their risk of developing depression, anxiety or other internalizing symptoms in middle childhood. The effect appears to be related to the way bacteria are linked to communication across emotion-related brain networks.
A new study from Linköping University finds that wastewater treatment plants emit significantly more greenhouse gases than previously thought. Drones measured methane and nitrous oxide emissions at 12 Swedish treatment plants, revealing a significant discrepancy between estimated and actual emissions.
Scientists have created a new type of germanium that is superconducting, enabling greater operational speed with less energy consumption. This breakthrough could revolutionize consumer products and industrial technologies, including future quantum circuits and low-power electronics.
Researchers discovered that people master new physical skills like sports or driving by combining lessons from error feedback and rewards, even with cues removed. The brain uses both feedback types in a mixed learning pattern, not separate processes as previously thought.
Researchers from the University of Queensland and New York University successfully made semiconducting element germanium superconducting. The discovery unifies classical electronics and quantum technologies, opening a pathway for hybrid quantum devices.
A new study from UC San Diego found that clinical pharmacists can play a crucial role in helping people with cancer and diabetes better manage their blood sugar. The study showed that patients referred to a diabetes management and education clinic led by pharmacists saw meaningful improvements in blood sugar levels over time.
Researchers identified 13 genes linked to obesity across six continental ancestries, including five previously unknown. These genes, expressed in brain and adipose tissue, are associated with increased risk of severe obesity, Type 2 diabetes, and other health problems.
Researchers found that soil microbes retain a long-term memory of past climate conditions, influencing plant responses to new droughts. Microbial legacies from drier soils improved native grasses' drought tolerance but not maize.
Researchers warn that advances in AI and neurotechnology are outpacing our understanding of consciousness, with potential serious ethical consequences. A better understanding of consciousness could have major implications for AI, prenatal policy, animal welfare, medicine, mental health, law, and emerging neurotechnologies.
Researchers at Institute of Science Tokyo developed a rapid cell-free method to capture detailed 3D structures of flexible sugar molecules, including the first atomic-resolution image of melezitose. The study offers a powerful tool for accelerating research in drug discovery and molecular biology.
A recent study from the University of Eastern Finland found that dancing alleviates perceived symptoms of depression, improves self-esteem and body awareness, and fosters self-actualization. Dancing reduces stress hormones and increases dopamine, allowing participants to process emotions in a creative, non-verbal way.
A Kobe University team identified the cause of pollutant accumulation in pumpkins and their relatives, discovering that specific proteins bind to pollutants and transport them through the plant. By controlling these proteins' behavior, safer crops can be created and polluted soils can be cleaned.