Mantle cell lymphoma treatment may be improved by considering a patient's biology and risk level, rather than age alone. High-risk patients can be identified at diagnosis and treated with targeted therapies, while low-risk patients may receive less intensive treatment.
Researchers have developed a new biological treatment that targets inflammation-driven scarring after a heart attack, aiming to reduce the risk of heart failure. The treatment uses donated human bone marrow-produced exosomes to dampen inflammation and promote healing.
Researchers at Uppsala University recalculated the Sun's silver content using a new model that predicts 55% more silver than previous estimates. This resolves a long-standing problem of missing silver in the solar system and improves our understanding of how elements are produced in stars and incorporated into planets.
Researchers have identified a new fungal species, Semicentenialea rex, representing a new class of fungi called Semicentenialomycetes. The fungus was isolated from roots in Sweden and has unique characteristics that set it apart from other rust fungi.
A new study published in The Lancet found that a dual-mobility total hip replacement (DM THR) can reduce the risk of complications, including joint dislocations, by up to 70%. This breakthrough implant design consists of a small ball encased in a larger plastic ball, providing better stability and reducing surgical complications.
A new book explores how prestigious classical music programmes in Europe, such as the Liszt Ferenc Academy of Music and Sibelius Academy, reflect notions of male genius and national character. Researchers found that contemporary teaching prioritizes promoting national composers and sound ideals, while also reproducing traditional methods.
A new study by Uppsala University researchers shows that internet-based CBT can significantly reduce symptoms of stress and anxiety in women with broken-heart syndrome, a condition often triggered by extreme stress. The treatment also helps patients better cope with emotions related to their illness.
The UCDP reported a record high number of armed conflicts between states in 2025, including eight interstate conflicts. The year saw the highest figure since World War II, with 65 conflicts resulting in over 244,000 fatalities, including a sharp increase in violence targeting civilians.
A new study of over 1 million young Swedish men found that the risk of atrial fibrillation is less than previously calculated, and the benefits of high fitness levels outweigh the risks. After age 40, the balance shifts in favor of higher fitness levels, suggesting that the benefits of exercise may be more significant.
A study of 43,000 Swedish politicians found that women are more likely to refrain from public statements due to fear of threats or harassment, especially on migration and gender equality. Politicians with an immigrant background also avoid making public statements, suggesting a need for increased voices and perspectives in policy debates.
The study identified amino acids crucial for ligand selectivity in two groups of receptors, β-adrenergic and D1-like dopamine receptors. By modifying these amino acids, the researchers made each receptor prefer its native ligand. The findings suggest that regions outside of the primary binding site also play a role in selectivity.
A new study reveals that four specific genes are crucial for the Atlantic herring's adaptation to low salinity in the Baltic Sea. The genes, expressed in sperm, eggs, and early embryos, enable the fish to reproduce successfully in brackish water.
A computer simulation improved understanding of refugees among Swedish teenagers who experienced simulated migration journeys. The study found that students exhibited increased social understanding and empathetic attitudes towards immigrants.
A new species of leaf warbler, Tokara Leaf Warbler, has been discovered in Japan through DNA analysis. The species is found only on two island groups and is considered vulnerable due to low genetic diversity and potential population declines.
Research found that exposure to the Swedish flag reduces aversion towards political opponents, indicating it can be a force for unity. The study, involving 1,200 participants in Sweden and 1,200 in Denmark, suggests that the flag reminds people of shared Swedish identity, leading to increased tolerance.
A new study found that antibiotics can alter the gut microbiome for up to four to eight years after treatment, with certain types of antibiotics having a stronger impact. The study analyzed data from 14,979 adults and found links between antibiotic use and changes in gut microbiome composition, including diversity of bacterial species.
A new study explores how religious faith can complement climate science, providing hope, meaning, and motivation for continued action. Faith-based activists in Sweden and South Africa reveal that spirituality gives them strength and direction to commit to climate issues.
A high-fiber diet has been linked to a reduced risk of coronary artery disease in night shift workers. The study, published in the European Journal of Epidemiology, found that consuming more fiber daily can lower the risk, with moderate intake recommended for those working night shifts regularly.
Researchers found that both screening methods lead to more cases of early-stage cancer being detected, especially in the first two years. The study suggests that screening may have a preventive effect by removing precursors to cancer.
In a new study, researchers at Uppsala University clarified family relationships in four graves from a 5,500-year-old hunter-gatherer culture at Ajvide on Gotland. DNA analyses suggest that the people were well aware of family lineages and that relationships beyond the immediate family played an important role. The analysis showed that...
Generative AI can play seven distinct roles in combating misinformation, including informer, guardian, persuader, and collaborator. However, its use also poses risks such as hallucinations and deliberate manipulation. To effectively combat misinformation, clear policies on the permissible use of AI are needed.
A new national registry study found that people with traumatic brain injury (TBI) have an increased risk of work disability, which can recur years after the injury. The study included nearly 100,000 participants and found that even minor TBI injuries can affect long-term employment.
Current early warning systems often fail to lead to action due to varied reactions to general messages. Researchers propose EW4All+U with personalized information based on location, mobility and circumstances. The technology exists, but challenges remain in scaling up solutions.
Researchers identified 11 genetic regions influencing gut bacteria and roles they play, including connections to gluten intolerance, haemorrhoids, and cardiovascular diseases. The study analyzed genetic data from over 28,000 individuals, providing insights into the complex relationship between genes and gut microbiome.
A new study from Uppsala University reveals a substantial increase in cardiomyopathy diagnoses in Sweden between 2004 and 2023, associated with high excess mortality rates. The study highlights the need for improved detection and targeted treatments to address this growing public health concern.
A Swedish study of prematurely born adults found increased morbidity in physical and mental health, yet they reported a high quality of life. The study, which followed participants from birth to age 26-29, suggests that premature birth does not necessarily limit daily life.
A new study found that choosing ARB drugs from the start can lead to better adherence and improved cardiovascular health. The study, which analyzed data from 340,000 patients, showed that ARB treatment resulted in fewer side effects and higher persistence rates compared to other drug classes.
Research analyzed blood samples from 1,800 individuals in Sweden, finding links between PFAS and PCB exposure and increased odds of multiple sclerosis. The study also highlighted genetic vulnerability and complex interactions between environmental contaminants and hereditary factors.
A new book by Uppsala University researchers reveals the secrets behind Nordic mediators' success in resolving conflicts. The authors analyze over 75 years of Nordic mediation experiences and introduce a new model for assessing successful results.
Researchers found that the healthy Nordic diet was more effective in reducing blood glucose levels and improving body weight, inflammation, and lipid profile compared to other diets. The study also showed that participants lost weight despite being allowed to eat as much as they wanted from recommended foods.
Researchers found a mosasaur tooth in North Dakota that revealed the giant reptile's ability to thrive in freshwater rivers. The study used isotope analyses to show that mosasaurs inhabited riverine environments in their final million years before extinction.
A new study reveals that Homo sapiens evolved in southern Africa for at least 200,000 years, contradicting previous theories. The analysis of 28 ancient genomes found genetic adaptations that shaped the species and unique variants linked to kidney functions and cognitive evolution.
A new order of marine sponges, Vilesida, has been discovered, producing unique sterols that support the hypothesis that animals evolved 100 million years earlier than previously thought. These compounds may also be used in the development of new antimicrobial and anticarcinogenic drugs.
A 40-year study on seed beetles found that strong sexual selection leads to rapid evolution of new species. Populations under high competition for mating diverged more rapidly and became genetically distinct.
Researchers at Uppsala University have identified a new genetic technique that enables targeting of tumour cells with elevated levels of proteins driving medulloblastoma. The technique, which works like a Trojan horse, introduces an enzyme linked to SOX9 sequence, killing tumour cells.
A team of researchers has identified a common sex-determining gene called ANTSR in both bees and ants, revealing a conserved mechanism that has been present for over 150 million years. This finding sheds light on the genetic basis of sex determination in these species and may have implications for bee conservation and breeding programs.
A new Swedish study found that breast cancer risk varies depending on the type of hormone in hormonal contraceptives. Desogestrel was linked to a higher risk, while levonorgestrel products showed a lower risk, indicating that some contraceptives may be safer options for women with a higher baseline risk.
A study published in the journal Bone found a clear link between osteomalacia and a fivefold increased risk of emergency caesarean sections or vacuum-assisted delivery. Vitamin D deficiency is a key underlying cause of osteomalacia, which may influence labor outcomes and increase the need for urgent obstetric interventions.
A new study based on responses from 5,500 people in Germany and the UK found that European voters overwhelmingly reject imposing trade tariffs. Despite being asked to support green investments and respond to Donald Trump's new trade policies, participants preferred other economic solutions over tariffs.
Researchers from Uppsala University uncovered the earliest occupation and creation myth links of the Karnak Temple, establishing a 4000-year history of human settlement. The team's analysis suggests that the temple was built on an island of high ground formed by river channels, reflecting Ancient Egyptian cosmogony.
Researchers tested an AI-supported diagnostic method at rural hospitals in Kenya and Tanzania, analyzing cervical cell samples and human papilloma virus (HPV) samples using digital tools. The study found that the AI method worked well technically but faced challenges with inconsistent images and follow-up care.
A Swedish study found that nearly all transgender individuals who undergo a legal gender change do not experience regrets, with only 21 out of 2,467 participants reversing their decision over 10 years. The study provides strong evidence for the stability of gender changes in this population.
A new survey of over 6,000 Europeans reveals that trusting politicians is crucial for accepting climate policies, especially those involving taxes. Regulations and subsidies tend to receive more support than environmental taxes or bans.
Researchers have identified distinct genetic adaptations in European cisco populations adapted to fresh, saline, or brackish water, as well as varying spawning times. These findings can inform sustainable management practices and improve our understanding of the impact of environmental factors on roe quality.
Researchers reprogrammed the epigenetic code to affect tumour growth and survival in multiple myeloma. This study presents a comprehensive map of epigenetic alterations in multiple myeloma, highlighting site-specific increases in DNA and protein methylation that control gene activity.
New research from Uppsala University reveals how plant-based meat alternatives became popular in Sweden through a combination of business, consumer and societal factors. Key findings include the role of documentaries like An Inconvenient Truth and the Swedish National Food Agency's sustainability recommendations.
Researchers at Uppsala University have developed an AI system that can detect subtle tissue changes indicative of prostate cancer, missing it from human pathologists. The study found the AI detected cancers in over 80% of cases where pathologists missed them.
Researchers at Uppsala University developed an AI model that can accurately predict battery ageing, leading to longer life and enhanced safety for electric vehicle batteries. The model reduces the need for sensitive vehicle data and provides a detailed picture of chemical processes inside batteries.
A study by Uppsala University found that parents of children with type 1 diabetes experience a significant drop in work-related incomes, particularly mothers. The impact is most pronounced for mothers of children diagnosed in preschool years. Long-term effects show that pension-qualifying incomes gradually decrease over time.
New research reveals that lake littoral zones store more carbon than previously thought, highlighting the need for inclusion in global carbon budgets. By including these zones, lakes may switch from being net carbon sources to net carbon sinks.