Researchers found that decompression with a nasogastric tube is linked to reduced complications in patients after oesophageal cancer surgery. This challenges declining trend of abandoning the tube post-surgery, which was previously thought to be safe.
An international research team has identified three key genes involved in controlling the invasion routes of glioblastoma. The study found that targeting these genes may lead to a potential new treatment strategy for the aggressive brain tumor.
A new study from Uppsala University found that most men with prostate cancer who receive recommended treatment have a good prognosis, with a lower risk of dying from prostate cancer than other causes. The study's findings highlight the importance of assessing a patient's life expectancy in choosing an appropriate treatment strategy.
A new study from Uppsala University shows that short teaching interventions on disinformation have no long-term impact on students' ability to distinguish between credible and misleading news. However, students who valued democratic ideals highly were better at identifying true and false information. The study suggests that isolated le...
A new study from Uppsala University finds that targeted training for healthcare professionals and parents significantly increases skin-to-skin contact between newborns and their parents in the first 48 hours after birth. This leads to improved health benefits for both the baby and parent, with a notable increase in the proportion of ba...
A new Swedish twin study found that genetics largely determine an infant's crying duration, with 50% of variation explained by genes at 2 months and 70% by 5 months. Environmental factors also play a role in infants' ability to settle during the first months of life.
Children of older mothers are more likely to be born prematurely or with complications. The study found that babies born to mothers 45 years and older had the highest risks of stillbirth, premature birth, and low birth weight compared to younger mothers.
Researchers at Uppsala University have created a model of human nerve tissue using 3D printing, enabling the testing of new drug treatments in a lab environment. This innovation allows for more precise medicine and could potentially lead to improved treatment options for ALS patients.
Researchers at Uppsala University predict that concurrent extreme events will become more frequent due to climate change, posing new challenges for preparedness. The study examines six types of events and finds a sharp increase in combinations of heatwaves and forest fires, as well as heatwaves and droughts, in various regions worldwide.
A new thesis on Uppsala University's Main Building delves into its architectural design, exploring how the building deviated from original plans. The study reveals the significance of antiquity-inspired themes, including a dragon mural and plaster casts of statues.
A new protocol has been developed to establish a safer standard for medication use during breastfeeding. The study focuses on the concentration of prednisolone and metformin in breast milk and infant plasma, addressing a significant knowledge gap in human lactation studies.
Researchers from Uppsala University describe a fundamental mechanism of antibiotic resistance, revealing how FusB works like a crowbar to rescue ribosomes from fusidic acid. The study provides new insights into the most prevalent type of fusidic acid resistance in Staphylococcus aureus.
A new study from Uppsala University found that people with high fitness levels in late adolescence have a lower risk of dying prematurely, but the association between physical fitness and reduced mortality risk may be overstated. The researchers examined data from over 1 million Swedish men and found no significant difference in the ri...
The discovery of a 355-million-year-old sandstone slab in Australia reveals the earliest clawed footprints ever found, challenging the long-held timeline of tetrapod evolution. The findings suggest that reptiles evolved significantly earlier than previously thought, impacting the entire evolutionary history of amniotes.
A new study from Uppsala University investigates how sleep deprivation affects biomarkers associated with cardiovascular disease. Researchers found that chronic lack of sleep increases the risk of heart problems by promoting inflammatory proteins.
A new AI model developed by Uppsala University accurately diagnoses multiple sclerosis (MS) with an overall accuracy of 90%, identifying the transition from relapsing-remitting to secondary progressive MS in almost 87% of cases. This enables earlier diagnosis, reducing the risk of patients receiving ineffective medicines.
Researchers found that babies from insecure backgrounds can still follow social cues, sparking hope for their development. The study used eye movement measurements and interviewed parents to assess a child's background and circumstances, concluding that some skills are intact despite trauma.
Researchers have discovered a way to regulate starch storage in algae using blue light-activated signalling pathways. This method has the potential to increase starch production in biofuels, improve nutritional value of agricultural feed supplements, and capture more carbon dioxide, reducing greenhouse gases.
A new thesis by Carin Leibring Svedjedal examines the language used in opinion pieces on trans-related issues, revealing a polarized debate that highlights alarmist examples and concerns about inclusiveness. The study also explores how transgender people use language to shape their identity and encounter difficulties in their environment.
A new study from Uppsala University found that 75% of women aged 24 wanted to have children, significantly lower than the 91% in 2014. The survey also revealed that 40 women stated they didn't want children due to various reasons, including uncertainty about the future and health concerns.
A new study by Uppsala University found that coffee machines in workplaces frequently produce coffee with high levels of cholesterol-elevating substances, which can affect LDL cholesterol levels and future cardiovascular disease risk. Regular drip-filter coffee makers filter out most of these substances.
Researchers from Uppsala University found that lymphatic endothelial cells have a lobate shape due to their capacity to change shape and increase overlap between cells. This shape supports resilience to changes in fluid volume and is also found in plant leaves.
Researchers have discovered five new species of fungi in the Piloderma genus, including one rare species found only in old-growth forests. The discoveries suggest that diversity in this genus is greater than previously thought and highlight the risk of species disappearance as forests are logged.
Researchers developed a new method to search through billions of molecules to identify potential anti-inflammatory drug candidates. The method uses computer algorithms to explore vast chemical space and has the potential to speed up the costly drug development process.
Researchers have discovered that giraffes maintain species-specific gut flora, even when eating different sets of plants. This finding has significant implications for the conservation of endangered giraffe species, highlighting the importance of understanding their diets and habitats to ensure their survival.
Researchers have uncovered the Fulani people's genetic diversity, tracing their history back to the Green Sahara period. The study found correlations between culture, geography, and genetics, highlighting the importance of Fulani subsistence strategies in shaping their genetic landscape.
CAR-T cell therapy has been shown to transfer CAR molecules to bystander T cells through trogocytosis, allowing the therapeutic effect to spread beyond the engineered cells. The study reveals that the transmembrane domains of these molecules regulate this process, potentially leading to improved efficacy and reduced side effects.
Researchers at Uppsala University found that people with psoriasis have invisible inflammation in their small intestine, which can lead to gastrointestinal problems and an increased risk of developing Crohn's disease. Half of the study participants had a leaky gut, allowing bacteria and harmful substances to leak through the intestinal...
Researchers at Uppsala University found that Semliki Forest virus penetrates the central nervous system by entering the cerebrospinal fluid and binding to VLDLR before penetrating deeper into the brain. This finding could be used to develop the virus as an agent for treating brain cancer.
A new study found that a unique population of large fish-eating herring has evolved in the Baltic Sea, exhibiting faster growth rates and lower levels of pollutants. These herring have adapted to the brackish water by switching from plankton-eating to a fish diet, with potential benefits for human consumption.
A new study from Uppsala University shows that an app can help parents who are mourning the loss of a child, reducing symptoms of prolonged grief and post-traumatic stress. The app provides four components: learning about grief, finding support, practical exercises, and a 'grief meter' to track feelings.
Researchers analyzed the effects of seven hormone treatments on blood clots, stroke, and heart attack in nearly one million women. The study shows that the risks differ depending on the type of treatment, with some linked to increased cardiovascular disease risk and others to no increased risk.
Researchers at Uppsala University analyzed fossilized feces of dinosaurs, revealing undigested food remains and plants, which helped recreate the structure of ecosystems during the Late Triassic period. The study suggests that early herbivorous dinosaurs' love for plant shoots was crucial to their evolutionary success.
Researchers at Uppsala University developed a mathematical model to understand how seabird species coexist on isolated islands. The model shows that different species use distinct fishing zones, maximizing energy intake based on traits like wing length and diving depth.
A recent study from Uppsala University found that genetic variation in cancer cells can enhance the effects of an already approved cancer drug, talazoparib, against liver cancer cells lacking a functional CYP2D6 enzyme. This suggests a potential for more individually tailored and effective cancer therapies.
Researchers at Uppsala University have developed a unique antibody that targets and delivers a drug package while activating the immune system. This '3-in-1 design' method has shown promise in treating several types of cancer by amplifying T cell effect on cancer tumors.
A new study found that beta blockers, commonly used to treat heart attack patients with normal pumping function, may lead to increased depression symptoms. Researchers observed more severe depression symptoms in patients who received beta blockers compared to those who did not.
Researchers found that HNL Dimer levels decrease rapidly within a day of successful antibiotic treatment, offering a time-saving advantage over traditional biomarkers. This study confirms the previous promising results and provides valuable insights for early diagnosis and treatment of sepsis.
A study by Uppsala University finds that childhood overweight is associated with socio-economic disadvantage, particularly in regions with high rates of single parenthood and low education levels. The prevalence of overweight among 4-year-olds has fallen to pre-pandemic levels, but regional disparities persist.
A new clinical model developed by researchers at Uppsala University accurately predicts the risk of hip fractures in the elderly. The model identifies patients at high risk without requiring bone density measurements, allowing for earlier preventive treatment.
Researchers found that seven common European forest trees have preserved their genetic diversity over millions of years, defying expectations. This resilience is attributed to unique characteristics such as long generation times and pollen dispersal capabilities.
A new study from Uppsala University found that nearly 40% of the public support rationing of goods like meat and fuel to reduce their climate impact. The study, which surveyed over 9,000 people in five countries, also showed that acceptability of rationing is on par with taxes for emissions-intensive food.
The European capacity for antibiotic research and development requires sustained investment to combat growing resistance. Collaboration and risk-sharing can help keep companies in anti-infective drug development, as a temporary funding strategy may lead to lost efforts.
A new study led by Uppsala University researchers found that a single treatment session playing the video game Tetris can reduce PTSD symptoms. After five weeks and six months, participants showed significant improvements in reducing intrusive memories and alleviating other symptoms.
A 175-year-old experiment by Carl Linnaeus shows pigs are pickiest eaters, eating 32% of plant species, while cows and horses rank lower, with goats preferring legumes and grasses. The study also reveals animals generally struggle to avoid toxic plants.
A survey of UK general practitioners reveals that 20% of doctors use generative AI tools like ChatGPT in their practice. The study highlights the potential benefits of AI in reducing administrative burdens and supporting clinical decision-making, but also raises concerns about errors, biases, and patient privacy.
Researchers developed a synthetic mucin gel inspired by cow slime to create a protective barrier around discs, preventing immune system attacks. This innovative approach may improve patient outcomes and reduce long-term complications after disc herniation surgery.
A genetic variant in the Syntaxin 17 gene determines the speed of hair greying and susceptibility to skin melanoma in horses. The study found three gene variants at the Grey locus, with the G3 variant associated with a higher risk of melanoma.
Researchers developed MUSCLE, a method that combines single-molecule fluorescence microscopy with next-generation sequencing to profile complex biological processes. The technique enables simultaneous observation of vast arrays of samples, uncovering general trends and dynamic signatures.
Researchers at Uppsala University used AI to predict the three-dimensional structure of a receptor, identifying molecules that bind to it with higher accuracy than traditional methods. This breakthrough accelerates the development of new drugs for mental health disorders such as schizophrenia and depression.