A new study published in The Journal of Internal Medicine found that having an unhealthy metabolic profile increases the risk of breast cancer recurrence by 69% and subsequent breast cancer mortality by 83% among survivors. This association was consistent across Europe, North America, and Asia.
A new survey reveals that 46% of Americans would consider eating a plant-based diet to help reduce greenhouse gas emissions. Shifting diets from meat and other animal products to plant-based diets has a high potential for reducing carbon footprints and mitigating climate change, as well as improving human health.
A new anomaly-based IDS system using machine learning and deep learning models achieves remarkable performance, detecting and classifying complex attacks in real-time. The system's top performer, CatBoost, sets a new benchmark for IoT security with 99.85% accuracy.
Aging-associated mutations in the Dnmt3a gene boost mitochondria power in blood stem cells, leading to clonal hematopoiesis. New mitochondrial-targeting drugs show promise in treating age-related illnesses by selectively weakening mutated cells without impacting normal ones.
Boston University School of Medicine has received PCORI funding to study the long-term effects of federal policy changes on opioid use disorder treatment. The study aims to identify where and for whom more patient-centered practices can be implemented.
A new study revealed that crocodylian ancestors thrived through two mass extinctions due to their adaptable dietary habits and varied habitats. This discovery may help scientists and conservationists better protect vulnerable species today.
Researchers from the Institute of Physical Chemistry, Polish Academy of Sciences, have identified unusual phosphorus molecules in space. These molecules, including phosphabutadiyne and vinylphosphaethyne, were studied using cryogenic techniques and infrared spectroscopy, providing new insights into their formation and properties.
A Lehigh University team developed a novel machine learning method to predict abnormal grain growth in materials, enabling the creation of stronger, more reliable materials. The model successfully predicted abnormal grain growth in 86% of cases, with predictions made up to 20% of the material's lifetime.
Insilico Medicine is presenting significant achievements in cancer therapy and immunology, including AI-powered discovery of potential therapies and novel solutions for unmet needs. The company's Pharma.AI platform has received IND clearance for 10 molecules, with promising results in Phase 2a clinical studies.
Dr. Sabine Ehrt takes the helm of microbiology and immunology at Weill Cornell Medicine, aiming to build on the department's reputation in tuberculosis research and expand into other areas. She seeks to foster cross-disciplinary collaborations and boost junior faculty mentorship.
Researchers at Brown University suggest that gold nanoparticles could one day be used to restore vision in people with macular degeneration and other retinal disorders. The nanoparticles, when injected into the retina, can stimulate the visual system and restore vision in mice with retinal disorders.
A University of Illinois expert warns that US consumers' sensitive DNA data is vulnerable when companies like 23andMe go bankrupt. The lack of comprehensive federal privacy laws and patchwork state regulations leave customers exposed to potential data breaches.
A new study found that listening to favorite music activates the brain's opioid receptors, explaining why it evokes strong feelings of pleasure. The release of opioids is also linked to individual differences in music enjoyment and may help develop new music-based interventions for pain management and mental health disorders.
A significant proportion of patients who suffer a stroke due to carotid artery narrowing can be treated with medication only. Researchers found that up to 75% of patients may not need surgery, eliminating the risk of another stroke and saving healthcare costs.
A team of experts at Cincinnati Children's reports achieving a milestone in growing human liver organoid tissue that faithfully reproduces key zones, nearly doubling rodent survival rate. This breakthrough paves the way for studying human liver biology and disease, accelerating drug development and potentially leading to repair tissues.
Researchers have developed a building material that uses fungal mycelium and bacteria cells, which can self-repair for at least a month. This innovation has the potential to replace conventional building materials with high carbon footprints like cement, reducing emissions and promoting sustainability.
Researchers at UC San Diego found that HPV DNA hybridizes with human DNA genes in oropharyngeal cancer cells, forming ecDNA that promotes tumor growth. This study suggests that selectively targeting ecDNA-disrupting therapeutics could slow tumor growth while leaving normal cells intact.
A new study from University of California San Diego suggests that climate trauma can have lasting effects on cognitive function, particularly decision-making. Researchers found that wildfire survivors were less likely to stick with choices that offered greater long-term rewards.
Aspiro Therapeutics is advancing an innovative inhaled therapy for asthma and COPD using peptidomimetics based on CC16. The treatment aims to address the underlying mechanism driving respiratory conditions, providing a more effective option for patients.
A study found that UK dog populations decreased by 0.9% annually from 1990 to 2021, with a rise in crossbreed and imported dogs. The research highlights concerns about inherited diseases due to limited genetic diversity in pedigree breeds.
Counterfactual SMOTE enhances machine learning models by generating synthetic data points near decision boundaries, reducing noise and improving detection of rare conditions. Tested across 24 healthcare datasets, it outperforms existing methods with a 10% average improvement in F1-score.
The study reveals six novel types of structurally and functionally distinct viral histone-fold proteins, some resembling bacterial and archaeal histones. These findings suggest diverse roles for viral histones beyond nucleosome formation, including potential functions in chromatin-related protein interactions.
A new study by ProtectedSeas highlights the potential of marine radar technology to monitor vessel speed violations with 95% confidence. The research found that radar can detect speed violations with high accuracy, enabling effective enforcement of speed limits and prevention of strikes on whale populations.
A new study from the University of Bath found that combining step tracking with mindfulness training boosts people's desire to exercise. Participants who used a mobile app for daily mindfulness practices increased their activity by 373 minutes per week compared to those who only stepped tracked.
Researchers developed a new method to measure changes in DNA that can help predict a person's age, focusing on how random chemical tags become over time. The study found that methylation entropy predicted age as accurately as traditional methods, with an average error of just five years.
A randomized clinical trial found no association between immediate skin-to-skin contact and improved neurodevelopmental outcomes in very preterm neonates. However, the intervention was shown to enhance breastfeeding practices up to 12 months compared to standard care.
The University of Missouri is partnering with a consortium to design and license a new research reactor, NextGen MURR, which will produce critical medical isotopes for cancer treatment. The project aims to enhance Missouri's role as a leader in nuclear science and medical research.
Researchers at University of Jyväskylä have isolated a new giant virus, Jyvaskylavirus, for the first time in Finland. The discovery reveals that giant viruses are more common in northern regions than previously thought, with implications for understanding microbial populations and ecosystems.
David Niven, a University of Cincinnati political scientist, has been awarded a $200,000 Andrew Carnegie Corporation fellowship to investigate the American polling system. His research aims to analyze how voters' experiences at the polls impact their views on voting.
Binghamton University is launching an Institute for AI and Society with $5 million in New York state funding, enabling researchers to tackle issues like online antisemitism and protecting power systems from malicious attacks. The institute will tap into the power of Empire AI, a consortium of public and private universities in New York.
A new method, CIBA, enables safe delivery of stem-cell-based treatments directly into the lungs of ECMO-supported patients. The technique has been proven to be well-tolerated and has shown potential for treating end-stage interstitial lung disease.
The National Center to Reframe Aging is partnering with the West End Home Foundation to provide evidence-based reframing strategies to change how we talk about aging. This partnership aims to strengthen support for aging services networks in Middle Tennessee, enabling leaders to drive real change.
Adapted Argentine tango dance therapy is helping some breast cancer survivors regain natural balance and sensation after experiencing neuropathy, a common side effect of chemotherapy treatment. The therapy aims to rewire the brain to improve function after chemotherapy-related nerve changes.
A study published in Brain reveals profound changes in the dopamine system in focal cortical dysplasia type 2, a congenital malformation associated with difficult-to-treat epilepsy. The findings suggest a disrupted dopaminergic system, which may contribute to the development of epileptic seizures and other symptoms.
A recent international study reveals that most people trust scientists and believe they should have a significant impact on society and policymaking. The study, conducted in 68 countries, found that public trust in scientists is high, with an average score of 3.62 on a five-point scale, indicating a fairly high level of trustworthiness.
Research published by the American Psychological Association finds that positive maternal parenting in childhood can foster key personality traits such as openness, conscientiousness, and agreeableness. Twin study data suggests that modest changes in these traits could lead to significant population-wide benefits.
A study published in JAMA Neurology found that GLP-1RAs and SGLT2is may have neuroprotective effects for people with Type 2 diabetes and those without diabetes. These findings suggest that these medications may slow the rate of cognitive decline in Alzheimer’s patients.
The ELion Intelligent Chinese Composition Tutoring System uses LLMs to evaluate student essays across four dimensions, providing detailed assessments and personalized feedback. The system has been instrumental in addressing teachers' excessive grading workloads and has facilitated the analysis of nearly 50,000 compositions.
A research team at HKU has developed a computational tool called Argo to track antibiotic resistance genes (ARGs) in environmental samples, providing insights into their transmission and associated risks. The tool uses long-read sequencing and can accurately identify and quantify ARGs, enhancing host identification accuracy.
The event brought together over 300 participants, including educators and students, to raise awareness about climate change and its effects. Participants engaged in DIY workshops and keynotes from experts in meteorology and education, highlighting the importance of cross-disciplinary cooperation and youth empowerment.
Researchers found that high tree mortality in upper canopy can promote oak regeneration when maple is removed from understorey. Plantings on thinned forest plots showed fewer signs of drought stress, supporting oak growth.
Researchers at UCL developed a new scoring system, CAR, to identify patients with narrowed carotid arteries who can be effectively treated with optimised medical therapy. The study found low rates of recurrent strokes and heart attacks among patients treated with medication alone.
The Research Organization of Information and Systems (ROIS) has upgraded the Science Information Network SINET6 to 400 Gbps, supporting international collaborations in high-energy physics research, medicine, and genetics. The upgrade enables faster and more reliable data transfer for researchers worldwide.
A team of climate scientists found that six major oceanic modes influence prolonged heavy rainfall in China, which can lead to severe flooding. Winter sea temperatures in the tropical Pacific can predict summer flood potential with 75% accuracy.
A new study links climate change to higher concentrations of inorganic arsenic in paddy rice, potentially raising lifetime health risks for populations in Asia by 2050. The research suggests a higher incidence of lung, bladder, and skin cancer, as well as cardiovascular disease and diabetes.
Scientists developed a machine learning model that incorporates factors such as genetics, lifestyle, and medical history to predict CAD risk. The new model outperformed the standard clinical model, identifying individuals at highest risk of developing CAD more accurately.
A novel cannula delivery system allows repeated, nondisruptive delivery of imaging agents to the mouse brain during long-term multiphoton microscopy. This innovation enhances longitudinal studies on brain function, disease progression, and potential treatments.
The detection of dimethyl sulfide and dimethyl disulfide in the atmosphere of exoplanet K2-18b provides the strongest evidence yet for biological activity outside our solar system. The signals are consistent with predictions for a 'Hycean' planet, but further observations are needed to confirm the findings.
A study found that microorganisms using the reductive tricarboxylic acid cycle dominate in shallow-water hydrothermal systems. This energy-efficient process enables them to transfer carbon into organic molecules, allowing them to survive in harsh conditions.
Researchers have discovered materials that shrink when heated, expand when crushed, and could restore old EV batteries to factory-fresh performance. This discovery represents a fundamental shift in understanding of materials science and has potential applications in construction and energy storage.
A new study by Ohio State University researchers found that households with both term and permanent life insurance policies were most likely to be financially prepared in case of an income earner's death. The study suggests having both types of insurance may be a strong option for many consumers, as most do not have enough coverage.
Researchers have uncovered the molecular mechanism of ATG-9 in regulating lysosome integrity by modulating phospholipid distribution. This study suggests that reduced ATG-9 scramblase activity facilitates lysosome biogenesis and repair, highlighting ATG-9 as a promising therapeutic target for diseases related to lysosomal dysfunction.
A Korean research team discovered that high concentrations of rose-scented citronellol can trigger neurological and behavioral toxicity. The study used multiple experimental models across species and found that citronellol accumulates in the brain, leading to neuroinflammation and damage.
Physicists at Harvard SEAS have created a compact, on-chip mid-infrared pulse generator that can emit short bursts of light without external components. This device has the potential to speed up gas sensor development and create new medical imaging tools.
A team of geoscientists from Rice University and partners have discovered a sharp, volatile-rich cap just 3.8 kilometers beneath Yellowstone's surface. This cap helps trap pressure and heat below it, suggesting the Yellowstone magma reservoir is actively releasing gas while remaining in a stable state.
The first BioAgora Cascade Funding Call concluded with the selection of two winning proposals: BRIDGING MINDS and CESPSIP Central-European SPSI Platform. The former aims to enhance engagement through gamification and science communication, while the latter seeks to strengthen science-society collaboration on BDS2030 policies.
Scientists at St. Jude Children's Research Hospital discovered FOXR2 activation in multiple pediatric CNS tumor types, including high-grade gliomas and pineoblastomas, with significantly different clinical outcomes. The study highlights the importance of combining molecular findings with other diagnostic approaches to improve treatment...
Researchers found a mature spiral galaxy, Zhúlóng, with a structure similar to the Milky Way's, challenging previous expectations that large disks take billions of years to form. This discovery suggests that spiral arms can develop on shorter timescales and may be short-lived in the early Universe.
Researchers at the University of Calgary investigate the effectiveness of transcranial magnetic stimulation combined with intensive speech therapy for treating poststroke aphasia. The study found significant improvements in speech, confidence, and mood among participants, offering new hope for those affected by stroke.
Researchers from HKUMed identified early mutations and risk factors for stomach cancer, laying the foundation for improved prevention and early detection. The study also developed a biobank of 'intestinal metaplasia' organoid models to study early cancer development.