A new study by the University of Cambridge found that seaside and blue-colored places are more likely to evoke feelings of nostalgia in people. The research suggests that these environments have visual properties that contribute to positive emotions, including 'fractal property' and high contrast.
A nationwide study of 1,500 US women aged 40-65 found that most continue to experience orgasm at the same frequency and quality as younger peers. The study suggests promoting masturbation among older women may enhance well-being and alleviate menopausal symptoms.
Researchers at MIT developed an implantable device that can store glucagon to counteract hypoglycemia, a life-threatening condition for people with Type 1 diabetes. The device, about the size of a quarter, contains a small reservoir made of 3D-printed polymer and can be triggered remotely or automatically by a sensor.
A new study published in BioScience found that cancer is incredibly rare in turtles, affecting only about 1% of individuals. The research, led by the University of Nottingham, analyzed medical records and necropsies from hundreds of zoo turtles, revealing tumours rarely spread.
Researchers developed a novel electroenzymatic platform enabling efficient non-natural oxidation reactions with high enantiomeric excess, opening a new chapter in biocatalysis for asymmetric synthesis
Researchers estimate 27 million tons of nanoplastics in North Atlantic Ocean, shedding light on the 'paradox of missing plastic'. The discovery highlights the significant amount of plastic debris that has been underestimated and raises concerns about its impact on marine ecosystems.
Scientists have recovered a protein sequence from a fossilized tooth over 20 million years old, revealing new insights into the rhino family tree and its divergence from other species. This ancient find expands the timescale for recoverable evolutionary-informative protein sequences by ten-fold.
A new multi-institutional clinical trial will test zipalertinib, an investigational drug targeting specific EGFR mutations in early-stage non-small cell lung cancer. The goal is to prevent recurrence and improve long-term outcomes for patients with limited treatment options.
Researchers demonstrated a record-breaking long-distance THz wireless transmission of high-definition video over 1.2 km using an astronomical telescope with a quantum-limited superconductor-insulator-superconductor mixer at 500 GHz.
The collaboration aims to increase print quality and consistency for large-format 3D printing, enabling applications in hydroelectric dams, oil and gas industries, and more. ORNL's slicing software and JuggerBot 3D equipment will be refined to process thermosets independently and simultaneously.
A recent study published in Nature reveals that weight loss triggers the breakdown and recycling of fats called lipids, potentially leading to improved health outcomes. Weight loss also clears out senescent cells, which are ageing and damaged cells that accumulate in tissues, reducing inflammation and scarring.
Researchers studied atomic-scale defects in single-crystal IGZO to understand its electronic properties. They found that oxygen vacancies and structural disorder contribute to device instability, but also detected a relationship between crystallinity and subgap states.
A new palladium-loaded a-IGZO catalyst achieved over 91% selectivity when converting CO2 to methanol, leveraging electronic properties of semiconductors. The study demonstrates novel design principles for sustainable catalysis based on electronic structure engineering.
A new approach uses DNA to fabricate targeted 3D nanoscale structures via self-assembly, allowing for complex designs and parallel assembly. The method enables significant time- and cost-savings compared to traditional top-down strategies.
Researchers developed a biomimetic codelivery system to target cancer stem-like cells, vasculogenic mimicry, and the immune microenvironment in triple-negative breast cancer. The treatment inhibits PKM2, suppresses CSC stemness, and reverses EMT, leading to improved therapy outcomes.
A research team developed a novel polyol process-based ruthenium catalyst synthesis method with improved ammonia decomposition performance. The new catalyst demonstrated more than three times higher efficiency compared to conventional catalysts.
Scientists have developed a new class of twistable materials, unlocking unprecedented quantum possibilities. The twist platform can engineer entirely new quantum states, including quantum spin liquids with potential applications in high-temperature superconductivity.
IHMT-15130, a selective BMX inhibitor, demonstrates robust efficacy in preclinical models of cardiac hypertrophy by suppressing inflammation and reversing pathological heart muscle thickening. The compound offers a safer therapeutic window for treating this major cardiovascular disorder.
Researchers developed a soft electroactive polymer eel-like robot that can explore underwater environments with minimal impact on wildlife and fragile structures. The robot uses dielectric elastomer material, enabling it to swim efficiently without causing harm to the environment.
A large prospective study found that a healthy plant-based diet is associated with an 8% lower risk of ulcerative colitis and a 14% lower risk of Crohn’s disease. Fruits and vegetables were identified as key protective factors against inflammatory bowel disease.
Researchers discovered a unique nanostructure in blue shark skin that produces their iconic blue coloration, which also suggests a potential capacity for color change. Tiny changes in guanine crystal spacing can alter the shark's body color to suit its environment.
A new study reveals that Alzheimer's risk genes influence tau buildup and spread in distinct pathways, challenging traditional views of the disease. Four gene types were identified: Network-Aligned Vulnerability and Resilience, and Network-Independent Vulnerability and Resilience.
Researchers developed an AI model that accurately predicts genetic mutations from routine pathology slides, reducing the need for rapid genetic testing by over 40% in lung adenocarcinoma patients. This innovation streamlines clinical decision-making and accelerates access to targeted therapies.
Rising ocean temperatures are causing higher concentrations of toxic algae in Arctic food webs, threatening the nutritional and cultural well-being of Alaska Native communities. Bowhead whales serve as indicators of this change, revealing a critical linkage between warming temperatures and increased bowhead toxicity.
New humanoid surgical robots offer a solution to the growing healthcare labor shortage, allowing for more efficient surgeries and reduced burnout among doctors. By taking on routine tasks, these robots can free up surgeons to focus on more complex procedures.
The study found that acute hepatitis E incidence and Disability-Adjusted Life Years (DALYs) increased globally from 1990 to 2021, with a slight rise in age-standardized rates. The number of incident cases is expected to continue increasing up to 2030.
The study created lightweight, highly deformable materials with tunable mechanical responses using one-DOF mechanisms. These materials enable rapid response switching and reprogramming of force-displacement curves, unlocking new customizable mechanical properties.
Researchers successfully demonstrate Fermi acceleration mechanism with ultracold atoms, unlocking new understanding of cosmic rays behavior. The technology has the potential for high-precision control over particle acceleration and opens new possibilities for investigating phenomena relevant to high-energy astrophysics.
A new study found that live contemporary dance performances trigger brainwave synchrony among audience members, signaling shared engagement. The researchers also discovered that the delta band of slow-frequency brainwaves was responsible for capturing this shared experience.
This review systematically presents China's agricultural biotechnology development, highlighting progress in functional gene discovery and transgenic technologies. The Chinese government has established a regulatory system to ensure safe application of biotech products, with steady annual growth in approved applications, focusing on GM...
At the 2025 American Library Association (ALA) Annual Conference, over 200 attendees engaged with the Sage-sponsored 'Banned Books from the Big Chair' exhibit, discussing book challenges and sharing advice to combat censorship. The event highlighted the number of challenged books and featured award-winning authors.
A pilot study evaluated Nutri, a clinical decision support tool for brief diet counseling in safety-net clinics. PCPs found the system usable and satisfactory, while patients effectively engaged with the intervention.
Researchers developed a novel model optimization algorithm named External Calibration-Assisted Screening (ECA) to enhance the prediction robustness of Near-Infrared Spectroscopy (NIRS) quantitative models. ECA rapidly adapts initial models to new detection environments by calibrating them with externally collected samples.
Researchers have developed an AI-assisted diagnostic system that can estimate bone mineral density in the lumbar spine and femur with high sensitivity and specificity. The system has the potential to transform routine clinical X-rays into a powerful tool for opportunistic screening, enabling earlier detection of osteoporosis.
Researchers found that 7-tesla magnetic fields accelerate demagnetization by 60% while suppressing efficiency by 34%, enabling widespread ultrafast demagnetization in other materials. Elevated temperatures enhance regulatory effects, promising real-world applications in high-speed storage and logic devices.
China experienced severe rainstorms and flooding disasters in 2024, with the Yangtze River basin and southern regions witnessing intense rainfall. The country saw its second-longest heatwave on record, while autumn typhoons displayed exceptional intensity.
A new study found that 4 in 5 adults in the US report some level of loneliness, strongly correlated with poor mental health days and physical health days. Women and Black individuals experienced higher rates of depression and poor mental health days than men and White individuals, respectively.
A study of 679 patients found that longer GLP-1RA treatment, not having diabetes, and higher body fat were associated with better weight reduction. Higher muscle mass and metabolic rate also contributed to successful weight loss in patients with overweight or obesity.
A new study predicts postoperative complications in children up to three days before formal diagnosis using wearable device data and novel metrics related to circadian rhythms. The results show 91% sensitivity and 74% specificity, indicating potential for facilitating faster treatment and care.
A new study found that verbal reaction time can detect sleepiness in older adults, a common safety risk. Voice analysis method reliably detected when someone was speaking versus silent with high accuracy.
Researchers have developed a novel composite electrode that stabilizes reactive oxygen species to facilitate methane activation and C–C bond formation. The study demonstrates superior methane production rates and selectivity, establishing a new paradigm for designing high-activity EOCM catalysts.
The Buck Institute is pioneering a cloud-based platform to simulate the dynamic behavior of microbial cells, overcoming current whole-cell models' limitations. The SIMBA project aims to advance our understanding of bacterial behavior and address critical challenges in biomanufacturing and national security.
Researchers developed novel PbWO4 filler-reinforced B4C/HDPE composites with tunable microstructures, achieving enhanced synergistic radiation shielding performance. The optimized composite achieved a 97.32% shielding rate against ²⁵²Cf neutrons and 76.43% against ¹³⁷Cs gamma photons.
Australian scientists used AI to generate a protein that can kill antibiotic-resistant bacteria like E. coli, a major step forward in combating superbugs. The new approach enables efficient de novo design of proteins with specific characteristics and functions.
A new study found commercially available body-cooling garments provide significant protection against extreme heat for laborers. Participants wearing cooling garments had lower internal temperatures and improved performance in tasks compared to those without, making these garments a valuable resource in hot environments.
A new study found that older people with diabetes who do not control their blood sugar levels are three times more likely to develop eye disease than those with controlled blood sugar levels. High glucose levels were also linked to an increased risk of glaucoma and macular degeneration.
A recent study has shown that large language models (LLMs) can accurately predict liver cancer treatment responses, offering a new path towards AI-powered precision medicine. The LLMs demonstrated predictive accuracy on par with senior doctors, while outperforming junior and mid-level clinicians in speed and accuracy.
Researchers at Rice University found that electrode materials' thermodynamic properties impact energy flow and performance differently. They showed that even with similar structures, some materials degrade faster under identical cycling conditions due to uneven lithium flow.
Despite falling birth rates and hospital delivery volumes, neonatal mortality has decreased significantly in Finland, particularly among preterm infants, according to recent studies. The findings support centralizing high-risk deliveries to university hospitals, while small delivery units continue to have low overall mortality rates.
A Northwestern University study finds disparities in peanut allergy prevention guidance, with low-income and minority parents less likely to receive accurate advice. Early peanut introduction cuts allergy risk by over 80%, but guidance is often inadequate for these families.
Testosterone therapy has been shown to safely restore physiological hormone levels in neutered dogs, offering a promising avenue to counteract the adverse health effects of neutering. The study provides crucial data for veterinarians to treat spay-neuter syndrome and improve long-term canine health.
A large study of Danish children found that COVID-19 mitigation policies affected BMI across all weight categories, not just those with obesity. The findings suggest that age and BMI class differences were present, warranting policies targeting all BMI groups in children.
Researchers discovered over 15,000 kilometers of ancient riverbeds on Mars, suggesting that the planet may have experienced warm and wet conditions for a geologically relevant period. The presence of fluvial sinuous ridges indicates that flowing water was once widespread in Noachis Terra.
Life expectancy in California remained lower in 2024 than in 2019, with COVID-19 accounting for a deficit of 12.8%. The gap between racial groups narrowed, but life expectancy in the Black population was still significantly lower than others.
Researchers have engineered high-affinity antibodies against malaria by incorporating domains from inhibitory receptors, allowing them to block the interaction between parasite proteins and host immune cells. This new strategy offers a promising approach for treating malaria and could lead to innovative antimalarial drug discovery.
M-MATISSE aims to unravel Mars' magnetosphere, ionosphere, and thermosphere using two identical spacecraft. The mission could provide crucial insights into the planet's habitability and evolution.
A compact all-solid-state CW SLM laser with high frequency stability was developed using iodine-based frequency locking, advancing its application in atmospheric remote sensing and environmental monitoring. The laser achieves long-term frequency stability with a drift of 4 MHz over a continuous 7-hour period.
The American Society for Nutrition (ASN) has announced that NUTRITION 2026 will be held in National Harbor, Maryland, near Washington, DC. The meeting will showcase the latest developments in nutrition science and feature top experts in the field. Abstract submissions open this fall, and award nominations will also be accepted.
The collaboration aims to develop a predictive, high-fidelity AI model that identifies disease mechanisms and predicts patient outcomes. This initiative will focus on cancer but may expand to other complex medical challenges, such as transplant rejection and immunology.
Located in the western Mediterranean Sea, the Caprera Canyon is home to a high concentration of cetacean species. The canyon's unique geography supports a diverse array of marine life, including whales and dolphins.
Researchers used a laser measurement system to capture airflow near ocean surface, identifying two coupling mechanisms that occur simultaneously. This breakthrough sheds light on air-sea exchange processes and could advance atmospheric and oceanic models.
Researchers developed a single-layer metasystem for 3D inspection of fine structural features, integrating transmission and reception functionalities into a compact architecture. The system achieves high accuracy, with lateral resolution errors under 10 µm and depth variations as fine as 20 µm.
Researchers developed an AI model that screens for cardiac amyloidosis with high accuracy, outperforming existing methods. The tool analyzes routine heart ultrasound images to quickly detect the condition and differentiate it from other heart issues.
Researchers investigate cannabis-based treatment to improve quality of care for hospice-eligible patients with dementia. A clinical trial will test T2:C100, a drug containing THC and CBD, to determine its effectiveness in reducing agitation.
Researchers used Playmobil kits to facilitate discussions about women's experiences of menopause at work. Participants shared their symptoms and ideas for making work easier during menopausal times, highlighting the importance of social support and flexi time. The workshop provided a safe space for powerful and meaningful conversations.
Mary Beckerle is stepping down as Huntsman Cancer Institute's CEO after 20 years of service. Brad Cairns will take over leadership, continuing the institute's mission to eradicate cancer.
A UK-backed mission, VERVE, is set to search and map gases rich in hydrogen that shouldn't be present on Venus. The probe will investigate potential biomarkers phosphine and ammonia, which could indicate the presence of microbial lifeforms.
Researchers found that disabling mERα signaling in osteoblast lineage cells reduced cortical bone mass and density, leading to weaker bones. This pathway is essential for maintaining bone strength and density, especially in females.
Liquid biopsy-based multi-cancer early detection (MCED) offers broad population and cancer-type coverage, minimal invasiveness, and high patient compliance. However, significant challenges persist, including balancing surrogate endpoints with public health benefits, detecting early-stage cancers, and minimizing false positives.
A recent study reveals that lactate-induced mitochondrial calcium uptake 3 aggravates myocardial ischemia–reperfusion injury by promoting neutrophil extracellular trap (NET) formation. The study found that MICU3-mediated mitochondrial calcium uptake leads to mitophagy and NET activation.
Researchers at Cold Spring Harbor Laboratory have discovered that cryptic mutations in tomato genes can increase or decrease the number of reproductive branches on plants. This finding has implications for agriculture and medicine, potentially leading to better crops and more effective medicines.
Clinical trials show that sutezolid and delpazolid are safer alternatives to linezolid, with strong antimicrobial activity and fewer side effects. These novel antibiotics have the potential to replace linezolid in TB treatment regimens, particularly for long-term use.
Researchers at Emory University have discovered that psilocybin can delay cellular aging by over 50% and extend the lifespan of human skin and lung cells. In a study involving aged mice, psilocybin was shown to increase survival by 30% and improve physical features, suggesting potential for anti-aging therapies.
Researchers found that after accounting for known differences, implicit bias in physician and hospital levels persists among Black, Hispanic, and Native American people with vascular disease. The AI model helps identify unconscious biases in clinical decisions.
Researchers discovered that psychological stress activates the NR3C1/NUPR1 axis, accelerating ovarian tumor metastasis through epithelial-mesenchymal transition. Elevated NR3C1 positively correlates with NUPR1 expression and poorer prognosis in ovarian cancer patients.
A team of researchers from The University of Osaka has made a breakthrough in weight loss treatment by developing a one-time genome editing approach that introduces a GLP-1 receptor agonist gene. This innovative method enables the body to produce its own weight-loss medication, reducing the need for regular injections.
New research claims adding lime to agricultural soils can remove CO2 from the atmosphere, rather than cause emissions. The study, based on over 100 years of data, shows that the addition of acidity is the main driver for CO2 emissions from soils.
This study reveals that SRSF7 promotes pulmonary fibrosis by modulating the alternative splicing of pyruvate kinase (PKM), leading to metabolic dysregulation and fibroblast activation. Lomitapide was identified as a novel modulator of SRSF7, effectively mitigating experimental pulmonary fibrosis.
The Chang'e-6 mission has returned samples from the Moon's farside, providing new insights into the lunar geology and thermal evolution. The samples revealed prolonged volcanic activity, a fluctuating magnetic field, asymmetric water distribution, and ultra-depleted mantle signatures.
A research team led by Virginia Tech's Fralin Biomedical Research Institute is working on a technique that uses focused ultrasound to deliver creatine directly to the brain. This method aims to restore normal brain mass in models of creatine deficiency, which can impair brain development and lead to severe cognitive challenges.
A clinical trial found that women experience stronger subjective effects of acute alcohol intake, such as drunkenness and sedation, compared to men. The study adjusted doses to achieve identical blood alcohol concentrations for both sexes, revealing that women's effects were more intense.
The journal publishes original research articles, reviews, and rapid communications on pharmaceutical sciences. Recent studies focus on nanomedicine-driven tumor glucose metabolic reprogramming for enhanced cancer immunotherapy and the linkage of circadian rhythm disruptions with Alzheimer's disease and therapeutic interventions.
A new study reveals that koalas only spend around 10 minutes per day on the ground, which is linked to two-thirds of recorded koala deaths. The research used GPS loggers and accelerometers to analyze fine-scale movement patterns, finding that koalas move with little urgency and spend most of their time in trees.
Researchers have unveiled the petrogenetic history of a newly identified Martian meteorite, offering unprecedented insights into Mars' volcanic processes. The study's findings suggest episodic melt extraction from a long-lived, depleted mantle reservoir, which has significant implications for reconstructing Mars' magmatic evolution.
Researchers generated high-quality haplotype-resolved assemblies of the MHC region in five widely used tumor cell lines. The studies identified numerous single nucleotide polymorphisms, indels, and structural variants surrounding HLA class I and II genes, providing valuable resources for cancer immunology research.
Researchers at Vanderbilt University Medical Center have developed a safe and effective fluorescent imaging agent that can assist surgeons in visualizing nerves during head and neck surgery. The agent, bevonescein, allows for intraoperative nerve-specific fluorescence visualization, reducing the risk of nerve injury.
Associate Professor Benjamin Mangrum's new book analyzes how comedy tackles technological advancements and their effects on human life. The book highlights the importance of humor in making technology seem ordinary and incorporating it into daily life.
Recent advancements in organic neuromorphic devices offer a promising solution for low-power, flexible computing. The review highlights the potential of these devices to overcome traditional computing limitations and contribute to next-generation systems.
A new study by Simon Fraser University warns that fish sounds and noise pollution are left out of critical conservation policies. This omission can have significant impacts on fish reproduction, population sizes, and ultimately, species survival.
A new study by researchers from Rice University has uncovered a mechanism by which the identity of nucleotides following a given nucleotide in DNA affects transcription accuracy. The discovery offers insight into hidden factors that influence transcription accuracy and may improve synthetic and therapeutic RNA.
A study published in Science Advances found that repurposing FDA-approved drugs can enhance the safety of nanomedicines by blocking complement activation and minimizing adverse effects. The research identified iptacopan, a drug approved for rare blood disorders, as a promising candidate for improving immune responses to nanoparticles.
A study published in Menopause journal found that four components of the Life's Essential 8 tool, including sleep quality, are key drivers of future cardiovascular risks. Healthy sleep, defined as 7-9 hours per night, may contribute to women's heart health and longevity.
MXene materials have been engineered to respond to light, enabling their use in soft robotics applications. This breakthrough could lead to the development of new types of robots that can change shape and function in response to external stimuli.
A University of Kansas professor's new book, 'On Bigotry', explores the concept of bigotry in a critical and nonpartisan manner. The book breaks down how bigotry functions, how it is taught, and its impact on individuals and society.
Researchers investigated differences between urban and natural soundscapes around the world, analyzing various descriptive indicators such as sound energy and variation in frequencies. The study found that green areas in urban settings often harbor a greater diversity of bird species than natural environments.
The study reveals that Hordeum bulbosum has a distinct genome expansion mainly at the chromosome ends. The team also decoded the Ryd4 resistance locus's structure in barley, providing a promising crop-wild introgression for resisting barley yellow dwarf virus.
A team of researchers has identified a molecular mechanism regulating the activity of NMTs, enzymes that modify proteins to regulate biological functions. The study reveals a potential new starting point for developing improved drugs targeting certain types of cancer and viral infections.
A UC study finds that murals are associated with higher foot traffic, denser housing, and increased cultural identity in Cincinnati's neighborhoods. The research also highlights the potential for murals to contribute to urban policy decisions, guiding investments in public art to achieve broader community development goals.
Compound heat-humidity extremes in eastern China are lasting longer than ever before, significantly increasing health risks for the elderly and young children. The study found that the active season has expanded, especially in South China, leading to a major public health crisis as China's population ages.
The Uncertainty-Aware Fourier Ptychography (UA-FP) framework offers a highly robust and flexible solution for computational imaging, overcoming traditional calibration constraints. It can maintain reliable performance even when confronted with substantial physical imperfections, setting a new standard for the field.
Researchers detected nanoplastic particles smaller than 1 µm in all depths analysed across the 12 measurement sites, with PET, PS, and PVC being the most common types. The study estimates around 27 million tonnes of nanoplastic are stored in the uppermost water layer of the North Atlantic.
Researchers developed a smarter QKD system using machine learning to synchronize quantum signals, achieving reliable self-correction in unstable timing. This breakthrough enables compact and cost-effective quantum communication systems for secure key sharing over long distances.
Researchers found that sewage spills from land to sea coincided with winds of at least 6.5m/s on 178 days within a two-year period, potentially sending microplastics into the air. The study suggests that coastal towns and cities may be exposed to billions of airborne microplastic particles.
Researchers identified four distinct groups of autism linked to specific genetic variants and biological processes. The study's person-centered approach analyzing phenotypic and genotypic data from SPARK enabled more precise diagnoses and personalized support.
A comprehensive analysis shows that sports fandom stems from evolutionarily ingrained tendencies which enhance social unity and therefore survival. The study highlights the role of cognitive biases, emotional connections, and heuristics in sustaining fans' beliefs.
Molecular simulations reveal that liquid carbon can form spontaneously into graphite even when diamond is the expected stable phase. The team found complex crystallization behavior and identified graphite as a stepping stone for diamond formation, explaining long-standing discrepancies in high-pressure carbon experiments.
A study by a trans-European research team reveals how DNA condensation during the cell cycle is regulated by a unique molecular switch. When cell division begins, the key enzyme CDK1 phosphorylates microcephalin and M18BP1, allowing condensin II to pack the DNA into sausage-shaped chromosomes.
Dr. Richard M. Peterson has been elected as the new president of the American Society for Metabolic and Bariatric Surgery. He aims to increase utilization of life-saving bariatric surgery, making it available to those who can benefit. The society reports over 270,000 metabolic and bariatric procedures performed in 2023.
A team of Penn engineers and materials scientists have developed a biomineral-infused concrete that captures up to 142% more CO2 than conventional mixes while using less cement. The new material is stronger, lighter, and uses fewer materials like cement.
A new study by Washington State University researchers reveals declining groundwater levels across Eastern Washington's complex aquifer system, threatening its sustainability. The study measures the water accessible to current wells and highlights areas of greatest concern, such as the Odessa region and Yakima Basin.
A new University of British Columbia study reveals that male guppies with more orange coloration are up to two times more sexually active and perform for females longer periods. The research identifies a genetic link between guppy color and behavior, suggesting healthier and fitter individuals may be more attractive to females.
Scientists have demonstrated a novel transition-metal-free dual-catalyst system for hydrocyanation, enabling excellent regioselectivity and high yields. The method avoids toxic metals and is estimated to be around 2,500 times cheaper than conventional methods.
Researchers successfully tested polarization-encoded quantum key distribution using a room-temperature single-photon emitter, achieving a QBER of 5.0% and secure key rate of 585.9 bps. The system minimized PMD impact by carefully selecting basis states.
A robot trained on videos of surgeries performed a lengthy phase of a gallbladder removal without human help, responding to and learning from voice commands. The robot performed unflappably across trials with the expertise of a skilled human surgeon, even during unexpected scenarios.
Scientists have identified a set of genes in zebrafish that reactivate after damage to the heart and patch it up like new. The researchers hope to use CRISPR tools to reactivate similar genes in humans and jump-start repair of the heart and other tissues after injury.
Four new species of dragon pseudoscorpions have been discovered in caves of South Korea, characterized by their unique dragon-like jaws. These blind creatures were identified through integrative taxonomy, providing insight into the biodiversity of cave-dwelling animals.
A 30-year study by Radboud University Medical Center found increased resistance in fungi, with over 2,000 resistant fungal strains collected. The fungus thrives in waste heaps and can cause aspergillosis in vulnerable patients, increasing the risk of death.
Eastern equine encephalitis virus (EEEV) is a rare but deadly disease in the US, caused by a mosquito bite. People at risk include those living near swamps or marshes and outdoor workers, such as farmers and campers.
Long-tailed macaques in a new study showed preference for videos featuring aggression and familiar faces, similar to human behavior. The research, led by Elisabeth H.M. Sterck, found that lower-ranking and less aggressive monkeys paid more attention to videos, highlighting the importance of social information gathering.
This study reveals that ALKBH3, an m1A demethylase enzyme, regulates enhanced glycolysis in Dox-resistant TNBC cells. The ALKBH3/ALDOA axis promotes Dox resistance through regulation of ALDOA mRNA stability and glycolysis.
Half of Brazil's high-potential areas for discovering new angiosperm species are located within protected indigenous lands. The study highlights the need for conservation priorities in these areas.
A retrospective study found teclistamab-cqyv to be effective in patients with high-risk, heavily pretreated multiple myeloma who would have been ineligible for the MajesTEC-1 trial. The bispecific antibody reduced disease burden by at least half in 53% of evaluable patients, and 45% achieved a 'very good partial response'. Despite a hi...
A new report from the University of Cambridge's Minderoo Centre for Technology and Democracy highlights the alarming trajectory of energy use by big tech companies, driven by AI growth. The report predicts that data centres could consume up to 8% of global greenhouse gas emissions by 2040, far exceeding current emissions from air travel.
The Human Oral Microbiome Database has been updated with a greater breadth of data, including 44 new human oral taxa and a total of 834 identified species. This expansion enables researchers to study the oral microbiome with greater precision and depth.
Researchers have designed a nanohybrid system that alleviates tumor hypoxia, promotes vascular normalization, and enhances antigen presentation. The system, combining PFBT@Rox Lip nanoparticles with photodynamic therapy, boosts anti-primary and metastatic tumor efficacy of immunotherapy.
Researchers have discovered batzelladins, which rapidly eliminate parasites that cause malaria, including strains resistant to conventional antimalarial drugs. The efficacy of these substances was proven through tests on blood samples from patients and infected mice.
Hypergraph research aims to improve network resilience by analyzing multi-way relationships, enabling more accurate representations of complex systems. By modeling projects within Texas A&M University as hypergraphs, researchers can depict interconnectedness and how individual work affects the entire system.
Teams developed a CO2 capture and conversion system that can handle a wide range of CO2 concentrations, even in the presence of oxygen. The system uses a zeolite adsorbent to rapidly adsorb CO2 and a separate catalytic reactor to convert it into a usable resource.
Restoration efforts have shown promising results, with satellite data indicating that restored peatlands' temperature and albedo improve over time. However, the return of vegetation is slower, emphasizing the need for additional measures.
Researchers found that tirzepatide significantly reduced body weight, food intake, and measures of appetite compared to a placebo and liraglutide. Functional magnetic resonance imaging revealed reduced activity in hunger-sensitive brain areas while viewing high-fat foods.
Scientists have developed a method to extract insect heart rates from video footage taken with digital cameras, preserving their natural behavior. The technique uses advanced signal processing and machine learning algorithms to analyze subtle body movements and detect accurate cardiac activity.
The journal is seeking original research, viewpoints, and tutorials exploring the use of AI-driven documentation in clinical settings. Submissions should address practical applications, challenges, and future directions of AI-facilitated clinical documentation.
A new study found that seafloor fish communities are maintaining their uniqueness despite widespread human impacts, with some regions showing increased diversity. The research suggests that conservation efforts should be tailored to each region to be effective.
A new photonic neural network developed in China achieves higher classification accuracy than digital models by using physical light transformations and multisynaptic optical paths. The system's design avoids errors introduced by translating software to hardware, marking a major step forward in optical AI hardware.
A novel AI-based approach identifies a distinct physicochemical signature near the cleavage site of gamma-secretase substrates, revealing dynamic properties essential for molecular recognition. The study highlights the potential of this methodology to improve understanding of gamma-secretase's role in diseases and aid drug development.
Health experts urge the UN to strengthen the treaty's focus on ending plastic production and reducing toxic chemicals. The World Health Organization estimates that one-quarter of global deaths are linked to environmental harm, including chemicals, pollution, and waste.
Researchers investigated the effects of vitamin D3-loaded nanoemulsion on adaptive behavior and language performance in children with ASD. The study found improved core manifestations and receptive and expressive language abilities, suggesting a potential therapeutic benefit for children with ASD.
Researchers found that random tree planting designs increase biomass by 11% compared to clustered layouts, while a more even spread promotes nutrient recycling. The study suggests that a balanced mix of species and spatial arrangement can optimize ecosystem functioning and productivity in forests.
Researchers developed a way to boost LLMs' performance on challenging tasks using test-time training. This method involves updating some model parameters using new data, leading to significant improvements in accuracy, especially for tasks requiring logic and reasoning.
Researchers at Boston University have found that exosomes released by obese tissues can turn slow-moving TNBC cells into highly mobile and invasive ones. This discovery could lead to the development of non-invasive biomarkers for metastatic risk and new drug targets like Rho-protein inhibitors.
Researchers developed a mechanically robust in-situ solidified polymer electrolyte inspired by the microstructure of dragonfly wings, offering superior mechanical properties and electrochemical performance. The innovative design and mechanisms may lead to significant advancements in SiOx-based anodes for lithium-ion batteries.
A new study published in Nature provides a comprehensive overview of all chemicals that can be present in plastics, their properties, uses, and hazards. The study identified 4,200 plastic chemicals as of concern due to health and environmental hazards.
The team built a high-resolution 3D structure of the Powassan virus, shedding light on its transmission and potential therapeutics. The findings could inform future treatments and preventions for this emerging tick-borne disease.
Artificial intelligence (AI) is revolutionizing medical needle procedures by providing unprecedented levels of accuracy and precision. AI-powered robots can assist physicians in complex tasks, enabling safer and more effective procedures. The four components of AI guidance are formalized, categorizing current systems into Eyes-on/Hands...
A recent study published in Addiction analyzed 268 critiques of alcohol and health studies by the International Scientific Forum on Alcohol Research (ISFAR) and found a strong industry-friendly bias. Studies supporting health benefits from alcohol were ten times more likely to receive positive reviews than those suggesting otherwise.
A new laser machining method enables high-precision patterned laser micro-grooving with root mean square errors below 0.5 μm. This technique allows for rapid and scalable manufacturing of custom microstructures, advancing applications in microfluidic devices, sensors, and heat dissipation systems.
Researchers analyzed four complete donkey skeletons and remains to discover that Egyptian donkeys were incorporated into ritual burials during the Early Bronze Age in present-day Israel. Local donkeys were also part of the diet, according to the study published in PLOS One.
Dr. Andy Jagoda has received the Edward W. Gilmore Lifetime Achievement Award for his significant contributions to emergency medicine education, leadership, and quality improvement. The award recognizes his lifelong commitment to advancing emergency medicine in New York City.
A new study has mapped the history of infectious diseases across millennia, offering insights into how human-animal interactions transformed our health landscape. The research analyzed ancient DNA from over 1,300 prehistoric individuals, revealing that zoonotic diseases became more widespread around 5,000 years ago.
A new polysaccharide from Houttuynia cordata improves survival rates and weight loss in a murine model of pneumonia caused by H1N1 and MRSA coinfection. The therapeutic effect is linked to the modulation of Treg/Th17 balance and NLRP3 inflammasome activation.
Researchers recorded activity from hundreds of neurons simultaneously in flying bats, revealing insights into neural replay and theta sequences. This study sheds light on the formation and storage of long-term memories in humans, potentially leading to new treatments for neurological disorders.
Researchers developed a blood-based indicator of organ age and found that individuals with young brains have a lower risk of developing diseases associated with their brain. The study also showed that organs' biological ages can predict health outcomes, such as increased risk of Alzheimer's disease for those with an old brain.
A new study from the University of Pittsburgh shows exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome. The research found that a specific compound called formate, produced by gut bacteria in exercised mice, was associated with better outcomes in patients with melanoma.
A recent analysis of 16 years of data on Japanese adults reveals a strong association between socioeconomic status and the incidence of five common cancers. Communities with low employment rates or low incomes show higher cancer rates compared to those with higher socioeconomic status.
Researchers from the University of Surrey investigate how senior citizens are targeted by cybercriminals due to societal biases, including ageism and stereotypes that portray them as frail and gullible. The study highlights the need for educational initiatives and support systems to empower older adults to protect themselves online.
A new AI-powered model has been developed to predict surface ozone concentration in the North China Plain and Yangtze River Delta regions. The model achieves high prediction accuracy, with hit rates of 83% and R² ≥ 0.85, providing a clearer picture of how weather patterns drive ozone pollution.
Researchers identified RTK dependent and independent mechanisms of resistance to EGFR targeted therapies in breast and head and neck cancers, highlighting opportunities for combination therapies and biomarker identification.
Researchers identified a family of RNA molecules, B2-SINEs, that stimulate growth in peripheral nerves and brain neurons after injury. These findings may lead to new treatments for nerve injuries and neurodegenerative diseases.
A new study from NYU Tandon School of Engineering found that users of Adblock Plus's Acceptable Ads feature encounter 13.6% more problematic advertisements compared to those without ad blockers, highlighting systematic failures in preventing inappropriate advertising from reaching children.
The Endocrine Society's new Scientific Statement identifies potential research directions to improve treatment options for people with type 1 diabetes. The statement highlights the need for population-based screening and more research into the causes of the disease.
A new online support package aims to empower parents of young autistic children to look after their dental health. The toolkit provides practical, tailored solutions focusing on toothbrushing, dentist visits, and eating habits, featuring videos and downloadable resources.
The new journal aims to accelerate knowledge dissemination in AI by prioritizing theoretical breakthroughs, practical applications, and societal implications. It features short peer-reviewed contributions and opinion pieces to facilitate swift engagement with contemporary AI issues.
Researchers at Chinese Academy of Sciences have measured the mass of silicon-22, revealing a new proton magic number. This finding provides deeper insight into exotic nuclear structures and nucleon interactions, shedding light on element formation in the Universe.
A new international study reveals that Skagerrak likely serves as a nursery area for young Greenland sharks, contrary to common associations with Arctic waters. The research also confirms that newborn sharks are born in undisturbed deep-sea areas near the Mid-Atlantic Ridge, south of Iceland.
A study by University of South Australia researchers found that regularly attending in-person events leads to greater positive emotions, joy, contentment, and excitement. In contrast, virtual events have no impact on other dimensions of wellbeing.
Researchers mapped the bone marrow T-cell atlas in CML patients, identifying a CML-specific T-cell population and its interaction with the bone marrow microenvironment. The study found that CD8 TE cells play a key role in regulating the CML immune microenvironment.
A new AI-powered model, PCWS, accurately predicts lung motion with a mean prediction error of just 0.20 mm, eliminating the need for 4D imaging. This approach represents a promising step toward personalized, low-risk treatment planning in lung cancer care.
Researchers explore innovative synchronous electrolytes to optimize zinc anode and halogen cathode performance. The review proposes promising candidates for enhanced stability and efficiency in aqueous zinc-halogen batteries.
Scientists have developed a method to reconstruct the temporal development of cancerous cells from a single tissue sample. This new technique, SCIFER, can detect aggressively growing clones and help identify individuals at risk for blood cancers like MDS.
Researchers at Harvard and TU Wien have developed a new type of tunable semiconductor laser with smooth, reliable, and wide-range wavelength tuning in a simple chip-sized design. This innovation could replace many types of tunable lasers with a smaller, more cost-effective package.
Research in Health Economics found that introducing school grades at younger ages may negatively impact children's mental health. Girls exposed to earlier grading were more likely to be diagnosed with depression and anxiety by the end of compulsory school, particularly those with low to moderate academic achievement.
A new study finds that climate change and aerosols have led to lower precipitation in the Southwest, making drought inevitable. The research predicts continued drought conditions as the planet warms.
This randomized clinical trial found that bedtime dosing of antihypertensive medication improves nocturnal blood pressure control and circadian rhythm without compromising daytime or 24-hour blood pressure. The study suggests potential advantages of bedtime administration for patients with hypertension.
A new type of star-like object, called 'dark dwarfs', could help solve the universe's greatest mystery: dark matter. These objects are powered by dark matter and may be found at the center of our galaxy.
Sara Freeman, a neurobiologist at Utah State University, has received the Council on Undergraduate Research Biology Mentor Early-Career Award for her exceptional mentorship of undergraduate researchers. She has mentored over 40 students and developed courses to encourage research involvement.
A new study by Mass General Brigham researchers finds that a transabdominal cerclage (TAC) significantly reduces the risk of preterm birth among patients with cervical insufficiency, with a 70% lower risk compared to transvaginal cerclage (TVC).
Researchers found that live well temperatures fluctuate drastically during tournaments, causing physiological stress and longer recovery times for largemouth bass. This study highlights the importance of optimizing live well conditions to minimize mortality rates and ensure sustainable fisheries.
A new AI model developed by Mayo Clinic and Ultromics can detect cardiac amyloidosis, a rare and progressive type of heart failure, with high accuracy. The model was validated on a large patient population and outperformed traditional screening methods in identifying the disease.
A new technique allows scientists to inject molecules into coral tissues, revealing thyroxine's positive effect on calcification. The study raises questions about the evolution of animal physiology and how corals utilize thyroxine in their natural habitat.
Researchers at Nanjing University have created a hydrogel-based iron-air battery system that can be rapidly assembled using common warm paste materials. The system generates electrical power by harnessing the thermal energy from iron powder in warm pastes, maintaining functionality even in sub-zero conditions.
Researchers propose a novel strategy to improve all-solid-state ion-selective electrodes by designing transduction layer materials with high hydrophobicity and large capacitance. The study reveals that ion-selective membranes constrain capacitive material performance, hindering sensor reliability.
Researchers developed a controlled 'living' click polymerization system to achieve well-defined polymers with narrow dispersity, enabling bidirectional synthesis of ABA-type block copolymers. The method leverages copper-catalyzed azide–alkyne cycloaddition and initiators to selectively drive monomer addition in a controlled manner.
A new study found that a nontargeted screening approach can identify more patients with hepatitis C virus infections than traditional targeted screening methods. The results highlight the need for improved treatment models, as patients who went from diagnosis to sustained virologic response increased significantly.
The largest review of antidepressant withdrawal studies found that most people do not experience severe withdrawal symptoms, with dizziness and nausea being the most common. Depression was not a symptom of withdrawal but rather an illness recurrence.
A new study from Uppsala University shows that short teaching interventions on disinformation have no long-term impact on students' ability to distinguish between credible and misleading news. However, students who valued democratic ideals highly were better at identifying true and false information. The study suggests that isolated le...
A new dual-spectroscopy technique, Surface Plasmon-Enhanced Dual Spectroscopy (SPEDS), has been developed to detect hazardous chemicals in complex environments. This approach combines SERS and P-DUS, achieving molecular-level specificity while maintaining real-time responsiveness.
Junk food brands have over 90 partnerships with top UK sports, including football and Formula 1, despite growing concerns over their impact on public health. Experts call for a ban on junk food sponsorship of sports to protect children's health.
Research finds that migrants living in cities with restrictive voting rights and favorable public opinion towards immigrants participate more frequently in protests. Perceived discrimination increases protest likelihood, while supportive public opinion lowers social and political risks.
The Moon-Rice project is developing a super-dwarf rice variety that can thrive in microgravity and produce high yields, addressing nutritional deficiencies in space. Researchers are also exploring ways to enrich the protein content of the crop to support astronaut health.
Researchers from Harvard University have discovered ancient proteins in the enamel of 18-million-year-old fossilized mammals from Kenya's Rift Valley. The study uses a new proteomics technique to reveal a diversity of proteins in different biological tissues, providing insights into the lives and evolution of these ancient animals.
A new study suggests Caligula was knowledgeable about medicine, particularly medicinal plants like hellebore, contrary to the traditional portrayal of him as a bloodthirsty tyrant. The Roman Empire's Antikyra spa town was renowned for its perceived efficacy in treating various ailments.
The revised guidelines incorporate the latest clinical advances in graft-versus-host disease prophylaxis, expanded donor options and search strategies. The updated guidelines aim to enhance transplant outcomes for patients with blood cancers and disorders.
Researchers will study how ocean currents and nutrients from land influence the health and productivity of MCEs, which support diverse marine life and important fisheries. The project aims to fill critical knowledge gaps and provide science-based solutions for environmental protection and sustainable growth in the gulf region.
Researchers at the University of Innsbruck have developed a versatile method to control dark excitons in semiconductor quantum dots using chirped laser pulses and magnetic fields. This allows for the storage and manipulation of excitons, enabling new opportunities for quantum memory control and entangled photon pair generation.
A new study analyzed 53 popular films and found that most depict idealized and aspirational views of puberty, romance, and relationships. This can lead to a disconnect between on-screen representations and real-life experiences, influencing how teens perceive themselves and their place in the world.
Researchers at the Salk Institute have identified a brain circuit that gives physical pain its emotional tone, revealing a potential target for treating chronic and affective pain conditions. The study found that a group of neurons in the thalamus can mediate the emotional side of pain in mice.
A study published in PLOS Global Public Health explores Somali women's perspectives on FGM/C and efforts to support its abandonment. The research found that many participants supported the abandonment of 'pharaonic' FGM/C due to its harms, but some continued to support 'gudniinka sunnah', citing cultural and religious reasons.
A randomized clinical trial found that SMART training improved cognitive gains in active-duty service members with mTBI, with significant benefits seen after just one-third of the training time compared to traditional SCORE protocols. The study suggests that SMART brain training can contribute to faster return to mission readiness and ...
A recent biochemical discovery has led to a potential treatment for HPDL deficiency, a rare disease that causes paralysis. Researchers treated an 8-year-old boy with an experimental compound that partially reversed his rapid decline, allowing him to walk long distances again and even run.
Research suggests that limiting information available to landlords may lead to increased discrimination against minority groups. Racial disparities were observed after a policy restricting background checks and eviction history was implemented in Minneapolis.
A study published in Science Advances found that higher childhood lead levels are significantly associated with a faster rate of forgetting, even at low median blood lead levels. Additionally, older children and those with higher maternal IQs showed better memory retention.
A research collaboration proposed a configurable topological photonic polycrystal based on a synthetic hybrid dimension, enabling multidimensional control over photonic states. The concept provides a platform for simultaneously manipulating multiple frequency bands, spin states, and group velocities.
Researchers from Tel Aviv University and the Israel Institute for Biological Research have developed an mRNA-based vaccine against pneumonic plague, a disease caused by Yersinia pestis. The vaccine showed 100% protection in animal models and offers hope for combating other lethal bacteria.
A new cell type has been identified in Burmese pythons that produces large particles made from calcium, phosphorus, and iron to digest bones. This specialized cell type helps limit excessive calcium absorption and is found in multiple python and boa species as well as the Gila monster.
A new fluorescent probe detects pyrethroids with high sensitivity and rapid results, visible within 10 seconds. The technology is portable and allows for easy detection using a smartphone.
Researchers identified four clinically and biologically distinct subtypes of autism, each with distinct developmental, medical, behavioral, and psychiatric traits. The study linked subtypes to genetic profiles and developmental trajectories, offering new insights into the biology underlying autism.
The American College of Medical Genetics and Genomics has released its updated 2025 secondary findings gene list v3.3, adding three new genes to the list and introducing a new publicly available webpage to aid clinical labs in determining reportable variants. The update aims to ensure patient benefit from advances in genomic medicine.
A study published in PLOS One found that childhood maltreatment speeds up biological aging and affects social behavior, particularly in reduced eye contact with human faces. This accelerated aging is linked to increased emotional and behavioral difficulties.
A new study suggests that EU agricultural policy can reduce carbon emissions by nearly a third and improve biodiversity recovery through strategic de-intensification. This approach involves adopting more sustainable farming practices, such as organic fertilizers, biological pest control, and low-input systems.
The partnership aims to address the region's skills shortage by offering flexible, evidence-based cyber education; 15 online micro-credentials are available for individual learners and organizations, spanning key areas such as AI security and incident response.
Researchers at Charité analyzed the laws of enzyme evolution on a large scale, revealing that certain areas change faster than others. The findings have implications for the development of new antibiotics and other medicines.