A recent study by Prof. Dr. Detlef Pollack reveals a dramatic decline in religious ties across the world, with secularization being a major factor. The study examines various factors contributing to this decline, including growing prosperity and individualization.
This study found that NKAPL downregulation in NSCLC is associated with poor prognosis and hypermethylation of its promoter. High NKAPL expression inhibits NSCLC cell proliferation, migration, and invasion. NKAPL enhances TRIM21 protein stability, leading to suppression of the NF-κB signaling pathway.
A new study found that slower arm movements in older adults increase the risk of falls, which can lead to hip fractures. The research team discovered that faster arm corrections can limit whole-body movement during a slip, highlighting the importance of strengthening targeted muscles.
Researchers discovered high-velocity clouds in the nearby spiral galaxy M83, which moved at speeds significantly different from the galaxy's overall speed of rotation. The findings suggest that these clouds originated outside the galaxy, providing new insights into how galaxies acquire fresh gas and sustain star formation over billions...
Agroecological methods improve biodiversity, pollination, natural pest control, and crop yields, but new subsidies are needed to support farms' transition. The study found that incorporating nature-friendly practices increases benefits for nature and farmers, with higher soil carbon and overall increased crop yields.
New research reveals that plants rely on multiple heat-sensing systems and a sugar-based mechanism to detect temperature changes. Sugar produced in sunlight helps plants grow taller even when thermosensors like phytochrome B are less effective. This discovery could lead to breeding crops more resiliently under stress.
Researchers have made a breakthrough in understanding malaria parasite proteins that could lead to targeted therapies. Two key proteins, PfRAP03 and PfRAP08, regulate gene expression in the apicoplast, a unique organelle found in P. falciparum. The loss of either protein led to parasite death, confirming their essential roles.
Researchers developed a miniature 'leukemia-on-a-chip' device that recreates human bone marrow and immune system to predict cancer immunotherapy success. The device enables real-time observation of how immunotherapy drugs interact with cancer cells in an environment closely mimicking the human body.
Researchers assess ligament maturation and movement impact on scoliotic conditions, providing new insights into the structural hallmarks of embryonic spinal ligaments. The study aims to identify potential connections between embryonic movement and spinal deformities in adolescent idiopathic scoliosis.
A new study synthesized over 70 publications on the 2021 heat wave, attributing it to a rare high-pressure ridge and increasing temperatures. The researchers predict that such events will become more frequent as the climate warms.
Researchers have deciphered a key mechanism for RNA therapeutics, explaining why certain modified RNAs evade the innate immune response. Pseudouridine modifications can avoid detection by pattern recognition receptors, such as TLR7 and TLR8, through impaired endolysosomal processing.
Researchers propose a paradigm shift toward an educational model built on human interdependence, urging a re-examination of success and purpose. The new approach emphasizes uniquely human capacities, creativity, emotional intelligence, and collaboration with AI.
Researchers uncover evidence of monumental structures built by hunter-gatherer groups at Kaillachuro, a collection of burial mounds in the Titicaca Basin. Burial activity evolved over time into stone masonry burial boxes covered by mounds of debris from ongoing rituals and remembrances of ancestors.
Researchers decoded the complex history of ancient Arles' aqueduct system by analyzing limescale deposits and building materials. The study confirmed that the basin functioned as a header basin upstream of an aqueduct arcade bridge, and revealed the role of large lead pipes in supplying water to different parts of the city.
Researchers used machine learning to simulate galaxy evolution and supernova explosions, achieving speeds four times faster than supercomputers. This breakthrough enables the study of galaxy origins, including the creation of the Milky Way's elements essential for life.
Scientists have found a way to track protein structures directly inside cells using natural proteins as tiny sensors, providing a more accurate and non-invasive approach. This method could help study disease mechanisms such as cancer and neurodegeneration.
A study of over 1,000 students found a strong association between lactose intolerance and nightmares, suggesting that changing eating habits could alleviate poor sleep. The researchers also discovered that people with food sensitivities were more likely to report negative dreams and poor sleep quality.
Paulina DeVito, a Ph.D. candidate in computer science at Florida Atlantic University, has been awarded the NSF Graduate Research Fellowship to pursue research on developing large language model-based approaches for analyzing public discourse on social media. Her work aims to understand how people discuss emerging technologies and infor...
Researchers at Beihang University derived capture zones of pulsed and continuous guidance laws for both pursuer and evader, highlighting their differences and influence factors. The study provides a theoretical guideline for guidance law selection in various pursuit-evasion games.
Researchers have discovered an oral drug called MA-5 that can improve both heart and muscle problems in patients with Barth syndrome, a rare genetic disorder. The drug boosts cellular energy production by up to 50% and protects cells from oxidative stress-induced death, addressing the underlying cause of the disease.
A new study led by RMIT University found that restoring southern Australian reefs from urchin barrens is feasible and beneficial for improved water quality, fisheries, and carbon sequestration. Economic modelling showed an AU$50 million investment would return up to AU$92 million in economic benefits.
The American Heart Association has appointed two new volunteer leaders: Lee Shapiro, a financial expert in health technology, as chairperson, and Stacey Rosen, a cardiologist, as president. Both experts have extensive experience supporting women's cardiovascular health and aim to accelerate innovation and strategic collaborations.
Jingyan Han has received a three-year, $300,000 AHA Transformational Project Award to study artificial blood vessels using 3D printing. Her research aims to improve understanding of vascular biology and disease resistance by investigating the role of cell alignment in vascular function.
A new approach to intersectional learning prioritizes individual diversity and promotes collective emergence. By understanding the degree of relatedness between individuals and issues, stakeholders can be involved in a wider range of themes, leading to increased community engagement and learner transformations.
A research team discovered a counter-ion competition mechanism that explains the superiority of negatively charged nanofiltration membranes in separating lithium and magnesium ions. This finding provides critical insights for designing next-generation NF membranes with tailored ion selectivity.
A computational study found amygdalin to be a promising therapeutic agent for HER2-positive breast cancer. The compound shows favorable binding energies and induces structural changes in the HER2 protein, suggesting its potential to suppress cancer-promoting activity.
A new AI-driven model accurately predicts interactions between microRNAs and drugs, expanding the target pool for novel therapeutic targets. The model showed higher accuracy than previous methods across three public datasets, with performance scores reaching up to 96%.
Kilonova Seekers, a public participation project, has announced its first major discovery - a bright exploding star named GOTO0650. The team collected highly complete dataset on the star through fast response from volunteers, suggesting it's a period bouncer and rare object to find in wide-field imaging surveys.
Pyruvate alleviates ulcerative colitis symptoms by targeting cPLA2, suppressing TNFα/NFκB signaling and reducing inflammation. Pyruvate preserves intestinal mucosal barrier integrity and normalizes tight junction proteins.
Dr. Danielle Beckman's research uses animal models to understand how viruses like COVID-19 trigger neurological damage and accelerate Alzheimer's disease. Her work has established critical connections between viral infections and neurodegenerative processes.
A new dual diffusion framework, Para2Mesh, has been proposed to achieve direct prediction from design parameters to adaptive meshes aligned with the flow field. This approach overcomes the limitation of previous methods requiring posteriori solution information, enabling more efficient and accurate computational fluid dynamics simulati...
The study found that HIV testing rates were higher among men, younger individuals, and migrants, while women, older adults, and those living in rural areas were underdiagnosed. The results also reveal significant differences by socioeconomic level and geographical area, highlighting the need for targeted interventions to improve adhere...