A new review in Frontiers in Science calls for a fundamental shift in how heart drugs are discovered and tested using AI, omics, and big data. This approach could drive the development of personalized treatments for cardiovascular disease, which currently relies on broad-brush treatments that don't account for individual variability.
A new drug combination has shown promising results in delaying the progression of advanced prostate cancer in patients with specific genetic mutations. The trial, led by UCL researchers, found that combining niraparib with standard treatment delayed disease recurrence and improved survival rates for eligible patients.
The June 2023 heatwave significantly disrupted phytoplankton blooms and stressed marine species. Rapid climate change increases the likelihood of such events, with about a 10% chance occurring each year.
Researchers found that instructions improve recall more than emotional associations, but sleeping doesn't significantly impact memory. They discovered that sleep spindles are linked to better recall of negative words, while slow wave sleep negatively correlates with total recall.
Researchers found that over 30% of children referred for Alport syndrome testing at age 3 already required therapeutic intervention, highlighting the potential benefits of early detection. The study suggests introducing a urine testing system may enable intervention before kidney dysfunction onset.
A new study by the University of Surrey finds that solar energy has become the world's cheapest source of power, with costs ranging from £0.02 per unit in sunny countries. The research highlights the increasing adoption of hybrid systems combining solar panels with batteries to create a more reliable and dispatchable source of power.
A recent study by Nagoya University researchers has revealed that zebrafish have enlarged areas in their spinal cords, corresponding to the paired pectoral and pelvic fins. The findings suggest an evolutionary theory: when tetrapods evolved from fish, only the paired fins transformed into limbs, while unpaired fins disappeared.
A renowned geneticist, Dr. Martin Alda, has made a groundbreaking discovery that bipolar disorder is composed of multiple genetically distinct disorders, transforming treatment approaches worldwide. His research also highlights the importance of combining basic research with clinical observations to advance psychiatric care.
Researchers found that seabirds use different strategies to find food, with scent-tracking birds benefiting visually hunting birds. This study provides insights into complex systems and crowd behavior, informing conservation strategies for procellariiform seabirds.
A new study argues that plants cannot survive without a minimum water supply, regardless of their genetic drought tolerance. Effective water management strategies, such as modern irrigation systems and soil mulching, have consistently stabilized or boosted yields, while genetic advances provide little protection once soil moisture fall...
Akassoglou's research discovered that blood protein fibrin causes toxic immune reactions in the brain, leading to neurodegeneration and disease progression. Her new immunotherapy aims to neutralize these effects, protecting against Alzheimer's and other neurological conditions.
A new study reveals that abandoned illegal cannabis operations leave a lasting chemical legacy on California's public lands, threatening ecosystems and wildlife. Researchers found persistent pesticide and pharmaceutical contaminants at former grow sites in the Six Rivers, Shasta-Trinity, and San Bernardino National Forests.
An AI-driven irrigation management system developed by Texas A&M University students uses soil sensors, crop data, and weather forecasts to optimize watering. The system conserves water, reduces costs, and increases crop yields, addressing global issues of water scarcity and inequity.
Shimon Sakaguchi's groundbreaking discovery of peripheral immune tolerance revealed a major unknown mechanism for autoimmunity, cancer, and inflammatory diseases. His work led to the identification of regulatory T cells, which act as the immune system's 'security guards', ensuring balanced responses and preventing self-destruction.
Scientists have developed a programmable electronic circuit that harnesses high-frequency electromagnetic waves to perform complex parallel processing at light-speed. This breakthrough has the potential to power next-generation wireless networks, real-time radar, and advanced monitoring in various industries.
A new study found that nearly half of middle and high school students reported experiencing psychological distress, yet received insufficient advice on avoiding tobacco. Health professionals need to offer guidance and assistance to prevent tobacco use among vulnerable youth.
Researchers identify pesticide toxicity as a major concern, while PFAS accumulation poses long-term environmental risks. The study advocates for reducing the number of chemicals produced and used to ensure regulatory control over their impact on humans and the environment.
A new method for constructing heterojunctions using a small organic molecule containing multi-terminal pyridine and graphitic carbon nitride improves charge separation efficiency. This approach promotes the extensive deposition and uniform dispersion of metal atoms, leading to high photocatalytic hydrogen production rates.
Researchers have made significant strides in understanding post-traumatic epilepsy (PTE), but a therapy to prevent its development remains elusive. Studies identify key barriers, including collaboration, funding, and standardization, and propose eight recommendations to advance PTE research. Potential therapies include disease modifica...
A new study shows that a multi-step effort to reduce unneeded pre-operative testing, using a tailored program for each hospital, can lead to significant reductions in wasteful tests. The findings have already spurred an expansion of the program to 16 more Michigan hospitals.
Researchers developed a nanotechnology strategy that reverses Alzheimer's disease by targeting the blood-brain barrier and restoring its natural waste-clearing pathway. The therapy achieved a significant reduction in amyloid-β levels and improved cognitive function in mouse models, showing promise for treating dementia.
Research reveals that Bifidobacterium breve in pregnant mothers regulates the placenta's hormone production, reducing complications and improving fetal growth. The study opens up a new approach to assessing pregnancy health through gut microbiome analysis.
A two-year field study reveals that biodegradable microplastics, often considered eco-friendly, are reshaping farmfield soils in unexpected ways. Bioplastics PLA reduced stable carbon compounds by 32% while boosting microbial necromass and fungal-dominated soil ecosystems.
A new study by researchers at Case Western Reserve University found that senior citizens prioritize social activities and inclusiveness over health. The study, which analyzed responses from over 388,000 patients aged 65 and older, also found that independence and family togetherness are important priorities for older adults.
The USC team created the first optical device that follows the emerging framework of optical thermodynamics, introducing a fundamentally new way to route light in nonlinear systems. The device uses simple thermodynamic principles to guide light naturally, without switches or digital addressing.
Researchers have developed a modified biochar made from biogas residue that can efficiently remove ammonium nitrogen from water. The potassium-permanganate-modified biochar achieved an adsorption capacity up to four times greater than unmodified biochar, making it a promising tool for environmental remediation.
Researchers found microplastic exposure changes the human gut microbiome, with some shifts resembling patterns linked to diseases. Microplastic-induced changes in microbial composition may serve as a bacterial stress response, potentially affecting overall well-being.
A study published in PLOS Biology finds no evidence of subcortical processing for selective attention, suggesting the auditory cortex 'turns up the volume' on focused sound. Researchers used novel experimental techniques to test this hypothesis using audiobooks and diotic and dichotic listening tasks.
Researchers found sulfur compounds with depleted sulfur-33 ratios in lunar mantle rock samples, contrasting with Earth's isotopic signatures. This discovery has implications for the evolution of the Moon and its potential exchange mechanisms.
The ASPIRE trial is a Phase III clinical study investigating whether adding chemotherapy to standard treatments can extend survival in men with advanced prostate cancer. The trial aims to determine the effectiveness of combining docetaxel with hormone therapy and apalutamide.
The project will develop prediction algorithms using AI and a novel cognitive assessment tool to identify individuals at high risk for crisis. The digital platform, available at no cost, will provide personalized models to predict clinical health outcomes, including symptom escalation, recovery time, and rehospitalization.
Researchers identified five behaviors that might make a caller seem suspicious, including conveying strong emotion and urgency, while poor communication or trying to make a favorable impression drew more suspicion. The study highlights the importance of understanding factors that prompt early suspicion to prevent wrongful convictions.
A new grading system for invasive squamous cell carcinoma of the lung has been proposed based on tumor budding, with tumors classified as low-grade (0-9 buds/0.785 mm²) or high-grade (≥10 buds/0.785 mm²). The system was validated in a test set and demonstrated improved prognostic accuracy and guide treatment decisions.
A new study reveals that both sugar-sweetened beverages (SSBs) and low- or non-sugar-sweetened beverages (LNSSBs) are significantly associated with a higher risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD). Replacing either beverage with water significantly reduces MASLD risk.
A nationwide study finds increased physician attrition rates in psychiatry, primary care, and obstetrics and gynecology specialties. Female physicians, rural practitioners, and those outside the Northeast region are at higher risk of clinical attrition.
A new study reveals the rules of protein tolerance to dehydration and rehydration, identifying key traits such as surface chemistry and function. The research enables novel protein design and potential applications in biotechnology, including extended shelf life for therapeutics and food.
Researchers developed a new control algorithm that enables powered knee prostheses to mimic natural human motion, reducing tripping risks and strain on users' bodies. The study showed significant improvements in activities of daily living, such as sitting, standing, walking, and climbing stairs.
A cross-sectional study found that high nurse workload and shift-level staffing ratios exert direct effects on reliable care delivery in neonatal intensive care units. High staffing ratios above 2 infants per nurse are recommended targets for workload reduction.
A new report highlights the potential of precision medicine to improve obesity prevention and treatment by identifying high-risk individuals and tailoring interventions. The authors emphasize the need for rigorous clinical trials to empirically determine the effectiveness of precision-based treatments.
The University of Texas at San Antonio has achieved a final total of $575 million raised for students, research, and growth through the Be Bold: A Campaign for Our Future initiative. The campaign was closed with a $5 million gift from the Malú and Carlos Alvarez Family, establishing the Carlos Alvarez Distinguished Presidential Chair.
Researchers discovered that bacteria living in Norway spruce needles can transform soluble gold into solid particles. The findings suggest that certain spruce-associated bacteria can facilitate the formation of gold nanoparticles inside needles, which could lead to environmentally friendly mineral exploration methods.
Researchers discovered that HIV embeds itself in unique DNA patterns across various tissues, including brain, blood, and digestive tract, explaining its ability to persist for decades. This knowledge can help identify targeted therapeutic approaches to eliminate infected cells or 'silence' the virus.
A newly identified antibody, 04_A06, has been found to block 98.5% of over 300 different HIV strains in laboratory tests. In humanized mice models, the antibody reduced viral load to undetectable levels, offering a promising approach for HIV prevention and treatment.
Dr. Emelia Benjamin will receive the award for her sustained record of excellence in teaching and mentoring early- and mid-career clinicians and researchers. Her research focuses on atrial fibrillation, mobile health, inflammation, and chronic pain.
Researchers have discovered how a family of genes in wheat regulates growth and grain development, leading to new possibilities for crop improvement. By examining the role of gibberellin-3-oxidase genes, scientists found that different gene variants can affect plant height and grain size.
A new survey by University of California, Irvine professor Nicholas Scurich found that 65% of Missouri voters believe Governor Mike Kehoe should commute Shockley's death sentence to life imprisonment. The survey revealed strong bipartisan support for clemency across all political affiliations.
A new study found that cardiovascular-related complications during pregnancy affect approximately 15% of pregnancies, with increases seen across all age groups. The rise in health risk factors before and during pregnancy drives these complications, emphasizing the importance of early identification and prevention strategies.
The conference will focus on pushing for universal, meaningful and affordable connectivity. The ITU estimates that about 2.6 billion people lack access to the Internet, with just over one-third of the world's least developed countries' populations online.
The Programmable Liquid-crystal Active Coronagraphic Imager for the DAG telescope (PLACID) will improve detection and direct imaging of exoplanets using liquid crystals. It can adapt to complex mask configurations, enabling direct imaging of circumbinary planets and proto-planetary discs.
Scientists have made the first-ever direct measurement of quantum uncertainty dynamics with attosecond resolution, revealing it's a dynamic and tunable property. The discovery enables novel petahertz-scale secure quantum communication protocols.
Scientists create flexible surface plasmonic waveguides that maintain efficient signal transmission even when stretched, bent, or twisted. The new design enables wearable materials to seamlessly integrate advanced sensing and communication functions.
Researchers at Johns Hopkins University created 'visual anagrams' using AI to study how people mentally process visual information. The findings reveal classic real-world size effects, even when objects are rotated versions of the same image.
A recent study highlights the growing concern of inhaler-related greenhouse gas emissions in the US, which have increased over the past decade. The study suggests that shifting utilization to dry powder and soft mist inhalers could be a key solution to reduce emissions.
Despite a 50% decrease in total local anesthetic poisonings, lidocaine-related incidents have increased by over 50% since 2016. The findings highlight the need for updated recommendations to mitigate risks associated with high-dose delivery methods and accidental overdose.
Recent studies published in The Journal of Nuclear Medicine have made significant breakthroughs in prostate cancer treatment, with multiple therapies showing promise. Researchers have also discovered ways to reduce radiation exposure in PET scans and tracked the effects of alpha therapy on patients.
The journal will benefit from improved publishing infrastructure and increased visibility for its published research. Phytologia Balcanica is an international journal in plant sciences, publishing original scientific articles across various fields.
A solar sail probe could provide a new vantage point for detecting space tornadoes, also known as flux ropes, which can disrupt Earth's magnetic field. These smaller features are too small for typical simulations, but a solar sail probe can help scientists see them and predict potential hazards.
A prospective cohort study found that young adults experiencing unfavorable patterns of cardiovascular health are at a marked increased risk for incident cardiovascular disease. Achieving and maintaining high cardiovascular health throughout young adulthood is crucial for preventing later-life cardiovascular disease.
Researchers Joseph Clark, Doowon Kim, and Joon Sue Lee received NSF CAREER awards for their groundbreaking work in chemistry, computer science, and physics. They are developing new methods to track pharmaceutical drugs and detect phishing websites, while studying the properties of quantum materials.
A new technology uses spent coffee grounds, polyethylene terephthalate, and potassium hydroxide to capture CO₂ from industrial processes. This method reduces environmental pollution, emissions, and greenhouse gases, offering a sustainable solution for waste management.