A Northwestern University-led team of astronomers used NASA's James Webb Space Telescope to capture the most detailed glimpse yet of a doomed star before it exploded. The study reveals that massive red supergiants rarely explode due to thick clouds of dust, but JWST's new capabilities can pierce through the dust to spot these phenomena.
Abel's projects aim to create locally specialized environments for enzymes, reducing energy consumption and increasing production efficiency in biomanufacturing processes. His lab will also develop modular metabolic reaction networks, combining components to efficiently build new biomanufacturing processes.
A study by researchers at Case Western Reserve University found that teaching patients to better understand social cues through targeted training programs can be more effective than traditional approaches. The study identified the crucial role of social inference skills in determining functional recovery from early schizophrenia.
A new analysis from UCLA researchers reveals significant wage disparities for Latinas across California counties, with a median earnings gap of 49 cents per dollar. In some wealthy counties, such as San Mateo and Santa Clara, Latinas earn just 38-37-34 cents per dollar, highlighting the need for statewide enforcement of pay equity laws.
Researchers assessed the impact of reactivity in red brocket deer on training efficiency, finding that calm individuals can learn commands like 'Come'. In contrast, more restless individuals had difficulty learning and following instructions.
Researchers have identified a group of cells called Y1 receptor-expressing neurons in the brainstem's lateral parabrachial nucleus as critical for regulating long-term pain states. These neurons integrate information about hunger, fear and thirst, allowing pain signals to be modulated by other brain circuits signaling more urgent needs.
Physicists at University at Buffalo have developed a user-friendly template for simulating quantum systems on consumer laptops. The new method, based on the truncated Wigner approximation, allows for efficient simulations of dissipative spin dynamics in hours, saving supercomputers for complex problems.
A new study shows that direct-to-consumer pharmacy pricing can offer lower total costs (431% lower) compared to commercial pharmacies for insured patients. Out-of-pocket neurologic drug costs are 75% higher, but most medications cost less than $635 per year.
A new study of the South Pole-Aitken basin reveals clues about the moon's interior structure, crust composition, and evolutionary history. The research suggests that the moon's near side was heated by radioactive elements from a magma ocean, leading to intense volcanism.
A new mRNA cancer vaccine platform has been developed using a hydrogel-based approach that actively recruits immune cells. This improves efficiency and leads to stronger antitumor immune responses in preclinical models. The research is still in its early stages, but it holds promise for future cancer treatments.
A multi-institutional study found that serially testing tumor samples can detect immune system activation in recurrent glioblastoma even when traditional imaging measures cannot. The researchers used multi-omic analysis and integrated data from various sources to show positive changes in the tumor microenvironment over time.
A study analyzing over 15,000 US treatment plants found that methane and nitrous oxide are the dominant greenhouse gases, exceeding current government estimates by 41%. The researchers identified opportunities for low-hanging-fruit reductions in emissions through fixing leaks and developing new technologies.
Researchers are collecting toenail clippings from Canadians to estimate a person's lung-cancer risk based on long-term radon exposure. The study aims to provide critical data for early screening and diagnosis of lung cancer.
Adhesion G protein-coupled receptors (aGPCRs) use a self-cleavage process to monitor their function. This process relies on multiple domain-extrinsic factors, ensuring efficient receptor activation and preventing faulty proteins from reaching the cell surface. The discovery provides new insights into how cells maintain quality control.
A recent study by Cornell University researchers found that both liberals and conservatives oppose censorship of children's literature unless it reflects their own ideology. The study highlights the polarization of an issue once governed by bipartisan consensus over protecting children from violent or sexual content.
The UJI is leading a project to develop advanced solid electrolytes for lithium and sodium metal batteries using additive manufacturing techniques. This will allow the ceramics industry to explore new avenues for diversification and promote knowledge transfer to the emerging regional energy storage industry.
Current minimum case volume standards for complex surgical procedures no longer align with contemporary best practices. Studies have shown that fewer cases are now needed to meet benchmark 30-day mortality rates over time.
Researchers at UCLA have identified a type of neuron in the orbital region of the frontal cortex that is most active when a decision outcome is unknown, suggesting these neurons play a crucial role in learning and mental flexibility. The discovery could aid the development of new treatments for rigid thought patterns such as anxiety an...
The DIST-ALERT system uses five satellites to receive more frequent images of global land surfaces, enabling scientists to track lands changing due to human activity, weather events, and natural causes. Land surface changes in 2023 were primarily driven by natural climatic variations and shifts in human-led management.
The University of Surrey is part of a global research project to create an 'Immune Digital Twin', a virtual model of the human immune system. This could help scientists tackle autoimmune disorders and infectious diseases by simulating how different drugs or treatments work for individual patients.
Researchers create novel antibody-based treatment that combines diagnostic and therapeutic capabilities to target LRRC15-expressing tumors, slowing growth and extending survival. The approach shows promise in preclinical models by priming tumors for immune response and boosting immunotherapy's effectiveness.
Researchers analyzed 659 posts on Reddit to better understand the role of social media in managing inflammatory bowel disease. The study found that patients use social media to track symptoms, manage medications, and cope with stress.
Researchers at UCSF have discovered a novel combination of immunotherapies that can reprogram the immune environment of colon cancer tumors in the liver. This therapy often eliminated tumors entirely in preclinical models, showing promise for treating patients with advanced colorectal cancer.
Researchers found that smoking and biological sex shape how normal cells evolve in healthy bladder tissue, with certain mutations gaining an advantage to expand into clones. This study offers new insights into cancer risk and prevention by providing a way to understand tissue evolution and identify early warning signs.
A study published in PLOS One reveals that ancient humans in central Italy butchered elephants for meat and raw materials, with a consistent strategy used during warm periods of the Middle Pleistocene. The site of Casal Lumbroso features over 300 skeletal remains from a single straight-tusked elephant alongside more than 500 stone tools.
Researchers have developed an efficient way to synthesize valuable compounds using alcohol dehydrogenase enzymes. The enzymes catalyze the formation of amides and thioesters from alcohols and amines or thiols, offering a clean alternative to traditional methods.
A study in Psychological Science found that chess players with lower Elo ratings exhibited greater overconfidence, even after receiving regular, accurate, precise, and public information about their skill. This suggests that overconfidence can be a universal aspect of human psychology.
Researchers at the University of Houston discovered that T. phoenicis can enter dormancy to evade detection, highlighting the resilience of spacecraft-associated microbes and raising concerns about planetary protection. The findings may lead to better detection methods and more effective sterilization strategies in various industries.
Researchers have identified key barriers to safely extending the life of solar panels and decreasing waste. One major challenge is the low cost of new panels undercutting the resale market for used systems.
Professor Dan M. Frangopol, Lehigh University's inaugural Fazlur R. Khan Endowed Chair, was recognized for his work on life-cycle civil engineering at the 21st International Probabilistic Workshop in Germany. He is widely credited with establishing this field and has authored over 500 peer-reviewed journal articles.
Researchers found that Medicare patients receiving federal housing assistance were diagnosed at earlier stages with breast, colorectal, and non-small cell lung cancers compared to peer patients. Early cancer diagnosis is key to better prognoses and has saved millions of lives.
Research found that defense cells of trained older adults are more effective against inflammation and metabolically efficient. Regular exercise modulates inflammatory response over time, reducing markers of inflammation and increasing anti-inflammatory markers.
Researchers at The University of Osaka have identified a previously uncharacterized subset of immune cells called preTfr that play a critical role in preventing autoantibody production. In patients with severe COVID-19, these cells are significantly reduced, correlating with increased levels of harmful autoantibodies.
Isha Jain wins NIH Transformative Research Award to develop new targeted treatments using modern science and techniques, potentially leading to personalized vitamin-based therapies for genetic disorders. Her lab has made key discoveries on oxygen levels and tissue damage, aiming to fine-tune these processes for disease treatment.
A study found that aphid populations in England are divided between the east and west, suggesting a strong link to lettuce-growing regions. The finding could complicate control efforts and highlights the need for region-specific approaches to tackle the pest.
A new statewide survey found that nearly two-thirds of Californians (63%) are directly or indirectly affected by domestic violence, while nearly one-third (31%) identify as survivors. The majority support jail alternatives and state-funded resources for survivors.
Researchers at NTNU developed a new system called SmartNav to improve GPS accuracy in cities. By combining various technologies, including satellite signals, carrier phase, and 3D building models, the system can provide high accuracy and reliability for self-driving vehicles, enabling confident and safe navigation.
A national registry has tracked nearly 4,000 patients with biliary atresia since 1989, showing that combined surgery and liver transplantation can extend survival well into adulthood. The study highlights the transformative power of nationwide data collection in reshaping treatment strategies.
Researchers analyzed 1.4 million online images and videos, finding that women are systematically presented as younger than men across various occupational and social categories. The study also found that mainstream algorithms amplify age-related gender bias in resume evaluations, rating older male applicants as more qualified.
Researchers have refined a powerful DNA sequencing tool to uncover hidden mutations in healthy tissues, providing insights into the earliest steps of cancer development. The study, led by the Wellcome Sanger Institute, analyzed over 340,000 mutations in cheek cells and identified key driver genes associated with cancer.
An open-label placebo treatment was associated with improved quality of life and reduced pain-related disability in patients with migraine. However, the treatment did not reduce headache frequency in this study.
Researchers at NC State University identified a hardware vulnerability that allows attackers to compromise AI privacy by exploiting ML accelerator behavior. The GATEBLEED vulnerability exploits power gating in AI accelerators, creating an observable timing channel for attackers.
Researchers found that successful coaches engage in post-season introspection, focus on creating a good team culture, and involve athletes in finding solutions. By practicing critical self-reflection and learning from failure, coaches can sustain success in the long term.
Researchers have generated a new ring-shaped protein nanomaterial capable of strongly binding to and neutralizing the SARS-CoV2 virus. The system can integrate therapeutic and diagnostic capabilities and be adapted to combat other viruses.
A global study found that introduced animal species have a greater impact on seed dispersal than native animal extinctions. Non-native mammals, such as pigs and rats, often replace native frugivorous birds, bats, and tortoises, affecting seed size and dispersal.
Climate change is predicted to increase suitable land for tea cultivation in China, with the overall range shifting northwards. Machine learning models were used to analyze China's four major tea-producing regions.
Researchers tested a user-carried safety device that prolongs survival under snow and gains valuable time for rescue operations. The study found that the device can sustain a buried person with patent airways for over 35 minutes.
Researchers analyzed the gut microbiome of a 1,000-year-old mummy from Zimapán, Mexico, revealing specific types of bacteria present. The findings expand knowledge of ancient microbiomes and may provide clues to the individual's life, including their diet, health, and lifestyle.
A new study found that breastfeeding until six months of age helps babies fight off infections and reduce chronic inflammation. The researchers identified specific lipids in breast milk, such as plasmalogens, which appear to lower inflammation and improve immune health.
A study found that 90% of marine aquarium fish sold by online retailers in the US come from wild populations, primarily in the western Pacific and Indian Ocean. The reliance on wild capture threatens coral reef ecosystems and puts endangered species at risk of extinction.
A national survey of first-year fellows in minimally invasive gynecologic surgery found significant gaps in the use of FDA-cleared containment systems during laparoscopic hysterectomy and myomectomy. The majority of fellows cited cost as the main reason for using less expensive, off-label retrieval bags instead of FDA-cleared systems.
The Indo-Swiss Workshop on 'Research Integrity in the Age of AI' brought together policymakers, scientists, and publishers to explore responsible AI use. Frontiers shared its pioneering approach to detecting research fraud using human-in-the-loop AI systems.
Dr. Amit Khera, a leading expert in preventive cardiology, will receive the 2025 Chairman’s Award for his groundbreaking clinical studies and contributions to the field of cardiovascular risk assessment. He is recognized for his tireless efforts to strengthen the American Heart Association's Scientific Sessions.
The BGU-RADAR Center, in collaboration with leading US universities, has developed a consensus statement on essential knowledge and skills for integrating medical cannabis into clinical practice responsibly. The statement outlines key competencies for healthcare providers to counsel patients effectively on medical cannabis use.
Scientists have identified two compounds, K102 and K110, that could promote remyelination and modulate immune function in multiple sclerosis. These compounds showed promising results in mouse models and human cells, suggesting potential for treating MS and possibly other neurological diseases.
Researchers at Michigan State University have discovered a crucial regulatory pathway in cyanobacteria that enables them to balance their energy demands and improve photosynthesis efficiency. The study reveals that the protein RpaA plays a key role in controlling carboxysome growth and integrity, allowing for better understanding of ca...
Researchers from Tohoku University have compared hot pressing and spark plasma sintering (SPS) in processing garnet-type oxide Li₇La₃Zr₂O₁₂ for solid-state lithium metal batteries. Both methods achieve nearly full densification and comparable ionic conductivity, challenging the long-held assumption that SPS is inherently superior.
Individuals with psychosis reported a large increase in current cannabis use following legalization, exceeding previous estimates for the general population. This finding highlights the need for policymakers to consider the potential health impacts of cannabis use on individuals with psychosis.
Researchers find that farmed totoaba could alleviate poaching pressures by establishing a regulated trade. The study suggests that a market-based solution may be more effective than a regulatory approach in curbing poaching. A $6 million subsidy program could make farming cheaper and prevent further decline of the wild population.
Scientists at Fralin Biomedical Research Institute are developing nanotechnology-based approaches to reprogram the immune system and overcome tumor defenses. Integrating nanomedicine with immunology promises more precise and effective therapies.