Researchers at Nagoya University have developed a new technology that improves protein production efficiency in E. coli by reducing ribosome stalling. By identifying short translational-enhancing peptides, they created an AI prediction model to accurately predict translation enhancement strength for all 160,000 possible tetrapeptides.
A comprehensive review of emerging neuromodulation techniques reveals their potential to treat treatment-resistant OCD. Targeting abnormal brain activity, these methods aim to normalize circuits underlying decision-making and emotion regulation.
Poor sleep quality affects over 1 in 5 residents in long-term care facilities, leading to increased medication use, falls, and delirium. Modifiable risk factors like pain management, medication review, and improved sleep routines can help mitigate these issues.
A new study reveals that different prey within a single species can provide vastly different levels of nutrition for marine predators. This variation can lead to predators consuming more prey than necessary, highlighting the importance of understanding prey quality in maintaining ecosystem balance.
Cancer Communications, a new journal published through the AAAS Science Partner Journal program, aims to bridge global oncology insights and clinical impact. The journal welcomes submissions on various cancer research topics, including clinical trials, epidemiology, and molecular biology.
Researchers at Kyoto University used LiDAR to measure the crown structure of 4,326 canopy trees across 23 forest census plots in Japan. The analysis revealed that canopy trees account for about 75% of total forest biomass across diverse forest types, providing a foundation for estimating total forest biomass and supporting sustainable ...
Researchers at UC Irvine have identified a molecular mechanism controlling the transition from acute to chronic pain. A newly proposed formula, which includes a modified diet rich in deficient nutrients, showed promise in blocking this transition in mouse models.
Researchers have identified genes with organ-preferential expression in sorghum stems, revealing distinct temporal functional signatures and potential candidates for genetic engineering applications. These findings offer valuable insights into improving sorghum stem biomass and composition for bioenergy and biopolymer production.
The ENCIRCLE trial found that the SAPIEN M3 system significantly reduced mitral regurgitation severity, improved heart failure symptoms, and quality of life for patients with severe mitral regurgitation. Over 95% of patients had little-to-no valve leakage at one year.
Recent discoveries in breast cancer biology highlight the potential of targeted therapies and molecularly guided treatment approaches. The review discusses various treatments, including monoclonal antibodies and immunotherapies, as well as challenges in treating triple-negative and HER2-positive breast cancers.
A novel post-translational modification, lactylation, plays a critical role in the pathogenesis of aortic dissection. Lactylation of mitochondrial adenosine triphosphate synthase subunit alpha impairs ATP production and increases reactive oxygen species generation.
Researchers developed ultra-low voltage optoelectronic polymer memristors to address high power consumption and complex integration in edge computing. The devices achieved a fingerprint recognition accuracy of 97.15% in a reservoir computing framework.
A new study published in Nature Geoscience reveals that China's cropland soils have stabilized in pH levels since 2013, linked to agricultural policy reforms. However, recovery has been slow and uneven across different types of farmland, with paddy fields showing signs of improvement but dryland soils remaining acidic.
Researchers developed a nanoparticle system combining lenalidomide and melarsoprol to activate the cGAS-STING pathway, promoting immunotherapy for HCC. The combination therapy significantly reduced tumor growth and improved survival in mouse models.
Recent advances in high-entropy oxide (HEO) memristors for neuromorphic computing have shown unique structural and electronic tunability. HEOs contain multiple cations in near-equimolar ratios, forming highly disordered yet stable lattices that resist phase segregation.
A novel cellulose-based piezoresistive sensor has been developed for interference-free respiratory rate monitoring. This customizable cylindrical architecture pairs MXene nanosheets with TEMPO-oxidised cellulose nanofibrils, enabling accurate tracking under different environmental conditions.
Researchers from China used CRISPR/Cas9 technology to knock out the GS9 gene in japonica rice, resulting in improved grain shape and reduced chalkiness. The study found no impact on yield per plant, making this a promising breeding strategy for improving rice appearance quality.
Researchers explore synergetic energy-coupled catalytic systems to overcome barriers in CO2 reduction, enabling more efficient and selective conversion of carbon dioxide into fuels and chemicals. Hybrid systems combine multiple energy inputs, such as light, heat, plasma, and electricity, to activate reactants and catalysts effectively.
Researchers developed a propeller-shaped molecule that changes its chirality in response to different solvents, demonstrating novel approach to controlling molecular chirality and optical responses. This finding paves the way for future applications in optical switching materials and quantum photonic components.
Scientists at Meijo University developed a new method to synthesize small-diameter single-walled carbon nanowires with a high density of long linear carbon chains. The breakthrough enables researchers to probe the properties of these unstable carbon chains, which have outstanding theoretical mechanical strength and thermal conductivity.
Researchers developed a laser-emission vibrational microscopy technique for rapid screening of hyperlipidemia, measuring viscosity of microdroplets in over 5,400 droplets in 90 minutes. The approach enables high-throughput analysis of biological fluids with promise for mechanical biomarker discovery and low-cost clinical diagnostics.
A new report maps Singapore's programs supporting children's mental health, revealing a strong foundation but also areas for improvement. The study identifies key recommendations to enhance coordination, funding, and child-centered practice, aiming to create a seamless support pathway for every child.
Researchers developed a high-performance TA/DTTA-2-TMT photocatalyst that synergistically optimizes four key steps in photocatalytic hydrogen peroxide synthesis, significantly improving overall catalytic efficiency. The material achieves exceptional H2O2 yield with broadened light absorption range and enhanced charge carrier separation.
A multiyear analysis of over 400,000 women and 28,000 breast cancer cases found a strong association between outdoor air pollution and increased breast cancer incidence. The study suggests that reducing car traffic and promoting alternative transportation can help mitigate this risk.
Researchers have discovered a promising new antibiotic, pre-methylenomycin C lactone, which is over 100 times more active than the current antibiotic methylenomycin A. This finding provides hope in the fight against antimicrobial resistance (AMR), which affects millions of people worldwide.
The study analyzed linked health data for over 57 million people in England, finding drops in cardiovascular disease incidence during the pandemic. However, diagnoses rates have returned to pre-pandemic levels, with increased cases of heart failure and inflammation of heart tissue observed after the pandemic.
A new study from UCL researchers found that cycling near misses are most likely to occur on roads without dedicated cycling infrastructure and during peak hours. The study used helmet-mounted cameras and GPS devices to track commuter journeys, resulting in 94 near miss events.
A new study found that different types of char can raise or lower greenhouse gas emissions from northern soils. Biochar tends to increase nitrous oxide emissions, while hydrochar suppresses it and even turns the soil into a small sink.
Researchers aim to restore healthy gene function in brain cells to treat severe neurodevelopmental disorders. The new technology could 'turn the volume back up' on genes silenced due to haploinsufficiency, uncovering potential therapeutic targets.
Researchers have discovered how to convert discarded plastics into valuable carbon-based materials, including graphene, nanotubes, and porous carbon. These materials show promise for use in environmental remediation, batteries, and supercapacitors.
Researchers found that plant roots can actively absorb CO₂ from the soil, with this process influenced by light, fertilizer, and atmospheric conditions. Root-based CO₂ absorption may be an alternative carbon nutrition pathway.
Researchers from The University of Osaka and The University of Tokyo have developed a novel technology that visualizes specific molecules inside living cells using light. The new photo-responsive alkyne tag enables precise visualization without disrupting molecular dynamics.
A new study published in TCT 2025 reveals that at least 4.7 million people aged 65-85 living in the US have moderate or greater valvular heart disease (VHD), and at least 10.6 million have clinically significant VHD. The prevalence of VHD increases with advanced age, highlighting the need for screening and treatment programs.
A study reveals how plate tectonics reshaped the planet, triggering conditions for oxygen-rich oceans and eukaryote evolution. The findings link deep-Earth dynamics to near-surface geochemical and biological evolution, offering a unifying framework.
A University of Phoenix survey conducted by The Harris Poll reveals widespread gaps in awareness about potential credit for prior learning. Many working adults skip development due to cost and scheduling barriers, while others don't know their work experience can be applied towards a degree.
A team of Pitt engineers has created self-powered spinal implant technology capable of transmitting real-time data from inside the body. The innovation utilizes new human-developed composites known as metamaterials to harvest energy and transmit signals wirelessly.
Researchers found that common viral infections shrink a queen's ovaries, reducing egg-laying capacity and methyl oleate production. This reduction triggers worker bees to prepare a new queen, which can lead to colony instability and economic losses for beekeepers.
A new sirolimus-eluting balloon has been shown to be noninferior to traditional treatments for in-stent restenosis. The study, presented at TCT 2025, found the balloon to be safe and effective for treating ISR without adding extra layers of stents.
A prospective cohort study found that individuals who accumulate their daily steps in longer bouts have a lower risk of mortality and cardiovascular disease. In sedentary participants, the association between longer stepping bouts and lower risk was more pronounced.
Research found that picture books often show boys experiencing more pain than girls, while girls are more likely to cry when faced with pain. The study also highlights the lack of representation of prosocial behavior, such as helping others in need.
A new study reveals that the strength of carbon monoxide adsorption energy relies on a mix of reaction factors, including catalyst material and voltage. This insight can guide the design of more efficient catalysts to convert CO2 into useful fuels like methanol and ethanol.
A study found that longer accumulations of steps in one go have a greater health benefit than short bouts spread out across the day. Walking continuously for 10-15 minutes per day was associated with lower risk of cardiovascular events and mortality.
The merger strengthens CRF's leadership in medtech, integrating Fogarty's expertise in early-stage innovation. The unified platform will accelerate breakthroughs into patient care, driving global progress in cardiovascular medicine.
The research aims to develop an intervention for incarcerated people to address the challenge of engaging with MOUD treatment after release. Massachusetts has received federal approval for a Section 1115 waiver to provide Medicaid benefits to incarcerated individuals, expanding access to healthcare and support services.
The study found that cutting balloon angioplasty is noninferior to intravascular lithotripsy in treating calcified coronary artery disease. The procedure is also less costly, making it a reasonable strategy for managing significantly calcified lesions.
Researchers have achieved breakthrough in understanding the universe thanks to a joint analysis between NOvA and T2K experiments. The study brings scientists closer to answering why the universe is filled with matter, shedding light on neutrino oscillations and their role in shaping the cosmos.
A new study of emerging adults reveals deep divisions in sentiments about firearms, with those fearing mass violence more likely to oppose firearm restrictions, except among young Republicans, conservatives, and men who view expanded access to guns as a solution.
The American Chemical Society (ACS) has published research topics that are creepy but contribute to improving human life, such as developing an alternative to animal testing and creating an edible protective coating for vegetables. These studies will inform future retinal health research.
Dr. Hani K. Najm, a world-renowned congenital cardiothoracic surgeon, has been named the next vice president of the American College of Cardiology. He will assume his role during ACC.26 and is committed to advancing heart health for all, building on the organization's mission to optimize patient care and outcomes.
A study found that super-high-pressure non-compliant balloons (NCB) are non-inferior to IVL balloon catheters for lesion preparation and stent expansion in severely calcified lesions. The results showed similar safety profiles and efficacy across various patient subgroups.
A large international study found that utilizing sirolimus-eluting balloons with bailout stenting only if necessary was noninferior to routine DES implantation for treating de novo coronary artery disease. The results showed comparable outcomes, including low rates of cardiac death and target vessel myocardial infarction.
Dr. Dong Chang has been awarded a prestigious R01 grant from the National Institutes of Health to develop a structured communication strategy that utilizes shared-decision making and time-limited trials to improve ICU care. The study aims to reduce non-beneficial treatments for critically ill patients with advanced medical illnesses.
A recent survey-based study found that even with forecasts of near-term job automation, Americans remain cautious but not panicked about losing their jobs to AI. Respondents showed modest increases in concern about technological unemployment, but policy preferences and economic outlooks remained unchanged.
Rates of medications for opioid use disorder (MOUD) use increased among surgical patients from 2016 to 2022, with buprenorphine being the primary driver. MOUD use was highest in debridement and orthopedic procedures, highlighting the need for clinical practice guidelines to coordinate care and pain management.
The SOLO project aims to identify knowledge gaps and propose novel approaches for the Soil Mission. Recent stakeholders' meeting in Alentejo, Portugal, discussed current projects and future directions.
Southwest Research Institute (SwRI) will predict F-16 landing gear component lifespan and recommend maintenance improvements under a $9.9 million contract. The seven-year agreement leverages SwRI's aging aircraft expertise in probabilistic analysis, fatigue testing.
A new study finds that an AI-powered lifestyle intervention is noninferior to human coaching in achieving a composite outcome in adults with prediabetes and overweight or obesity. The AI-led Diabetes Prevention Program was noninferior to the human-led program in terms of weight reduction, physical activity, and HbA1c levels.
A small study found that five volunteers with late-onset Alzheimer's disease showed significant improvements in cognitive tests and decreased biomarker tau proteins after two years of receiving 40Hz light and sound stimulation. This suggests that the therapy may slow cognitive decline and have direct biological impacts on Alzheimer's p...
Researchers discovered that rapidly increasing temperature during material thermal processing leads to more orderly crystal growth and smoother charge transport. This results in a substantial improvement in efficiency of eco-friendly solar cells made from antimony selenide, an abundant and eco-friendly material.
Researchers at UC San Diego School of Medicine developed an AI-powered approach to decode macrophage gene expression patterns. They identified a 53-gene signature that separates reactive from tissue-healing macrophages, resolving a longstanding debate in Crohn's disease.