Researchers at Nagoya University have developed a method to detect hidden matter around black holes by analyzing changes in ringdown waves. The study found that hidden matter affects ringdown differently depending on its pressure arrangement around the black hole.
Researchers at Nagoya University have built a graphene nanoribbon that can switch its twist using a natural solvent, opening opportunities for new optical switches, chemical sensors, and spintronic components. The discovery uses a natural chiral liquid to lock in a single spiral direction, with a high degree of helical bias.
Researchers have discovered a new material, LLNOF, with a record-high conductivity of seven millisiemens per centimeter, comparable to liquid electrolytes. The material's high conductivity is due to a dynamic interplay among four atomic sites that form a tetrahedron around the fluoride ion.
Researchers identified a compound, PF-04457845, that slows ALS progression in mice, with potential as a therapeutic option. The compound targets N-acyl taurines, which correlate with ALS progression, and has been proven safe in humans.
Researchers at Nagoya University developed a new way to lower the resistance of p-type GaN contacts by depositing an ultrathin magnesium layer and applying a brief heat treatment. This approach achieves a contact resistivity of (1–3) × 10⁻⁴ Ω cm², a significant improvement over existing methods. The new process has promise for accelera...
Researchers at Nagoya University developed a new delivery vehicle for circular RNA (cirRNA) using a novel lipid nanoparticle, FL0445-LNP, which improves the stability and efficacy of mRNA-based therapeutics. The technology has potential applications in cancer vaccines, genome editing, and protein supplements.
A recent study by researchers at Nagoya University found that low-frequency noise below 100 Hz can cause blood vessel damage to kidneys in mice. The study suggests that the frequency of noise matters more than its loudness, with high-frequency noise having no effect on kidney function.
Researchers developed a new approach to eliminate pathogenic bacteria like Porphyromonas gingivalis in periodontitis without harming healthy tissue. This therapy preserves beneficial oral microbes, reducing bone loss and improving oral microbiota in mouse models.
A recent study by Nagoya University researchers found that orexin neurons play a crucial role in regulating motivated behavior. Using novel rat models, they discovered that activity in orexin neurons increases with effort, helping drive motivated behavior.
Researchers at Nagoya University have developed a method to modify the inside of molecules, creating chiral nanocarbons with unique shapes and properties. These new materials exhibit spiral-shaped light emission, multiple electrical charges, and gas storage capabilities.
A field experiment on wild kittiwakes found that birds with high energy costs during breeding raised more chicks the next year, but at a cost to their own survival. The study reveals how flexible energy use can lead to hidden trade-offs in life-history strategy.
Researchers at Nagoya University discovered that complement C3 protein acts inside tumors to prevent immunosuppressive cells, improving cancer immunotherapy effectiveness. Higher levels of C3 in tumor tissue were associated with better treatment outcomes and survival rates in patients.
Researchers designed an end-to-end workflow to identify new blue OLED materials using AI and quantum chemistry. They developed a virtual library of over 19,000 molecules and used machine learning to select promising candidates, which were then experimentally evaluated and found to have high color purity and efficiency.
Researchers at Nagoya University review the latest results of plasma agriculture, finding that well-tuned plasma treatments boost seed vigor or yield in over two-thirds of studies. Plasma-induced epigenetic changes also promote positive expression of plant genes involved in germination and stress tolerance.
The team created a method to form dome-shaped bumps on nanofilms in water using a computer-guided electron beam, which can be flattened, reshaped, or repositioned as needed. The technology has potential applications in cell movement and nanorobot power systems.
Researchers developed gallium-doped zinc oxide nanosheets that can detect red, green, and blue light while remaining nearly transparent. These nanosheets enabled the detection of full-color images with half the error of conventional cameras, making them suitable for demanding environments like space hardware and automotive systems.
Scientists used clues from label data, chemical analysis of tiny shells, and ocean current simulations to trace the voyage of a plastic bottle cap. The study found 307 organisms, including a polychaete worm not found in Japanese waters before, highlighting the potential for micro-ecosystems to be transported over extended periods.
A cross-cultural study found that people across six countries divide mental capacities into two broad groups: Perceptual-Experiential (emerging early) and Reflective-Evaluative (emerging later). This structure suggests a shared, intuitive framework for understanding mental development.
A study published in Science Advances reveals that Earth's ionosphere contributed to the majority of ring current ions during a record-breaking super geomagnetic storm in May 2024. This finding highlights the importance of understanding how much Earth's ionosphere contributes to the ring current, as it may be essential for accurately p...
A brain enzyme has been found to build polysialic acid chains on itself, regulating its own activity. The sugar chain acts as a switch, suppressing the enzyme's function when attached. Once removed, the enzyme reactivates outside the cell, offering a new mechanism for regulation and repair.
Researchers at Nagoya University developed an AI tool, DiSPAH, to estimate ALS disease progression speed and identify muscle decline patterns. The study found six distinct patterns of disease progression among patients, with some experiencing rapid deterioration while others declined slowly.
Researchers developed a nanowire device that selectively captures cancer-related extracellular vesicles from the blood serum of ovarian cancer patients. The technology uses high-performance zinc oxide nanowires and achieves efficient capture of cancer biomarkers with minimal physical burden on patients.
Researchers developed a silver nanoparticle-based technology to precisely cut and join DNA at targeted sites, increasing assembly efficiency by 2-5 times. The process uses chemical reactions instead of restriction enzymes, resulting in higher DNA recovery rates and improved joining efficiencies.
Researchers at Nagoya University identified the neural circuit responsible for timing torpor in mammals, which reduces body temperature and metabolism. The discovery provides new insights into how animals regulate energy use.
Researchers at Nagoya University have discovered a copper-dependent sensing system in plants that detects hydrogen peroxide, a key signaling molecule involved in stress responses and immunity. This finding paves the way for improving crop resilience and understanding plant responses to environmental stress and pathogens.
Researchers develop machine learning analysis method SPERRFY that combines datasets on brain region connections and gene activity. The study finds a 'GPS' system of genes that predict which brain regions are connected, supporting the chemoaffinity theory and offering new avenues for research into brain development and disease.
Research at Nagoya University suggests that individuals with higher autistic traits use labeling as a way to cope with uncertainty, reducing emotional stress. The study found a link between autistic traits and lower anxiety levels when people are able to put their feelings into words.
Researchers discovered that KD025 restored neural connections and improved memory and visual recognition in mice with schizophrenia-associated gene variants. The drug also reduced ROCK2 overactivity without causing serious side effects common to current medications.
Researchers at Nagoya University have developed a new method called SMART that accelerates enzyme evolution and reduces costs by accelerating the selection period from weeks to days. The system uses mRNA display, next-generation sequencing, and bioinformatics to identify superior enzyme variants.
Researchers found that clonal hematopoiesis accelerates aortic aneurysm progression and that commonly used osteoporosis drugs can slow or halt this process. The study identified a key mechanism by which macrophages contribute to extracellular matrix degradation, providing a potential non-surgical approach for treating aortic aneurysms.
A recent study analyzed blood samples from over 11,000 seabirds worldwide to estimate oceanic mercury distribution. The analysis found that mercury levels vary according to prey trophic level, bird body weight, and foraging depth, with distinct regional patterns of contamination.
Researchers have discovered that native soil bacteria can degrade persistent pollutants like dioxins without genetic engineering. Using decoy molecules, the bacteria's natural enzymes are tricked into breaking down these toxic compounds.
Scientists in Japan developed a high-resolution X-ray telescope using precision mirror-making technology, capable of distinguishing objects 3.5 mm wide from 1 km away. The telescope was tested on the ground using a unique evaluation system before launch on the FOXSI sounding rocket mission.
Researchers at Nagoya University found that a brief spike in testosterone after birth causes muscle-wasting disease to develop decades later. Treating the disease at birth significantly reduced nerve cell breakdown in adult mice.
Researchers have identified and overcome metabolic instability as the key barrier to developing ovalicin, a potent relative of fumagillin. Using chem-bio hybrid synthesis, they created metabolically stable drug candidates that worked in animal models of amebiasis.
A new deep learning model classifies Japanese Sue ware from 3D scans with high accuracy, using three-dimensional point clouds directly. The model achieved an overall accuracy of 93.2%, performing almost perfectly on visually distinct categories, while focusing on regions that may correspond to expert archaeologists' considerations.
Researchers at Nagoya University present six advances in gallium oxide thin-film growth, including a world-first result growing the material on low-cost silicon substrates. The new High-Density Oxygen Radical Source doubles atomic oxygen density, promoting chemical reaction and film growth.
Researchers at Nagoya University found that magnetic fields keep the equator spinning faster than the poles in stars, preventing a rotation flip even as they slow down with age. This contradicts 45 years of theoretical predictions and could help scientists solve stellar mysteries.
Researchers have demonstrated that stem cell treatment can be effective even when initiated after motor deficits appear in cerebral palsy. The study used stem cells from human primary tooth pulp to treat chronic-phase cerebral palsy in rat experiments, showing improved motor and learning functions in the treated group.
Nagoya University researchers have developed an iron-based alternative to expensive chiral ligands in metal-based photocatalysts, achieving a precise radical cation cyclization and the first total asymmetric synthesis of (+)-heitziamide A using blue LED light and abundant iron.
A new study from Nagoya University and Gifu University found that multisensory museum experiences can engage visitors with culturally significant heritage. By incorporating sensory elements like smell and touch, visitors can form personal connections to the artifacts, leading to deeper engagement and conservation efforts.
Two gut bacteria, Akkermansia muciniphila and Bacteroides thetaiotaomicron, work together to destroy intestinal mucus, leading to dry and immobile stool. This discovery explains why standard treatments often fail for millions with chronic constipation, including those with Parkinson's disease.
Researchers at Nagoya University developed an AI system called YORU that recognizes animal behaviors with over 90% accuracy. The system combines real-time video capture with optogenetics to selectively target brain cells driving specific behaviors, offering a major breakthrough in social behavior studies.
A recent rat study identified the neural mechanism underlying chills, a cold sensation that supports the body's response to infection. The findings suggest that prostaglandin E₂ boosts cold signals from the lateral parabrachial nucleus to the central nucleus of the amygdala, triggering chills and promoting warmth-seeking behavior.
Ovarian cancer cells recruit protective mesothelial cells in abdominal fluid to form hybrid cell clusters that resist chemotherapy. These clusters use spike-like structures called invadopodia to invade surrounding tissue. The discovery opens new treatment possibilities and could help doctors monitor disease progression.
Scientists at Nagoya University identified a brain circuit that keeps mice awake in unfamiliar environments, releasing neurotensin to maintain wakefulness and protect against potential dangers. This discovery may explain the 'first night effect' in humans, where the brain remains vigilant on the first night in a new place.
A new AI-powered model predicts patient survival and risk stratification for spinal metastasis, allowing for more informed treatment decisions. The model achieved high predictive accuracy using large-scale clinical data from Japanese patients.
Researchers at Nagoya University found that about half of wood mice take time to examine nuts before selecting, potentially increasing their exposure to predators. Despite this risk, the extra time investment pays off as picky eaters are more likely to select undamaged chestnuts.
A new study from Nagoya University in Japan has found that petrolatum-based eye ointments can cause MicroShunt glaucoma implants to swell and potentially rupture. The study suggests that clinicians should avoid using these ointments on patients with the implant, particularly when it is exposed outside the conjunctiva.
The Nagoya University ISEE Award has recognized Professor Hiroyuki Yamada's pioneering work on high-altitude penetration flight observation techniques for typhoons. His research enabled scientists to observe the complete vertical structure of typhoons, providing unprecedented data on storm intensity.