Scientists discovered two rotational growth modes: free rotation and restricted rotation, which impact CNT structure and quality. Free rotation allows for high-crystallinity growth, while restricted rotation leads to structural distortions and defects.
The Society for Neuroscience will convene approximately 20,000 neuroscientists to share cutting-edge research across over 8,000 presentations. Registered media will have exclusive access to world-renowned experts and emerging science.
Research reveals specific OBI-associated pre-S mutations accelerate cell cycle progression and tumorigenesis by hijacking the LHBs-Akt/mTOR axis. Targeted kinase inhibitors show promise in suppressing mutation-driven hyper-proliferation, providing a new strategy for combating occult hepatitis B-related liver cancer.
Researchers argue that aerial robots should turn language instructions into verifiable measurement queries before flight actions to ensure safety. This framing connects semantic goals to technical constraints important in flight, such as movement feasibility and uncertainty reduction.
Researchers have determined the cryo-electron microscopy (cryo-EM) structure of E. coli TGT, overturning a prevailing model for bacterial TGT function. The study reveals the enzyme binds to two tRNAs, providing a more complete picture of protein modification and potential antivirulence targets.
Researchers identify CNTD1 mutations as a cause of diminished ovarian reserve, characterized by reduced ovarian follicles and compromised fertility. The study establishes CNTD1's essential role in maintaining ovarian function and preserving the follicular reserve required for female fertility.
A new study reveals that hepatocytes release soluble Tim-3 protein to limit immune-mediated damage in response to drug-induced liver injury. The protein binds to Galectin-3 and Galectin-9 to regulate immune cell infiltration, providing protection against subsequent damage.
Researchers designed an end-to-end workflow to identify new blue OLED materials using AI and quantum chemistry. They developed a virtual library of over 19,000 molecules and used machine learning to select promising candidates, which were then experimentally evaluated and found to have high color purity and efficiency.
A new framework, FAIRS, improves responsive and statistical bounding performance of uncertainty maps by accounting for non-Gaussian residual behavior. It enhances the responsiveness and reliability of ionospheric corrections in high-precision positioning applications.
A new study found that prescribed burns reduced giant sequoia mortality by 77% and increased survival chances fourfold during the 2020 and 2021 Sierra Nevada wildfires. The research integrated remote sensing data to quantify pre-fire fuel structures and estimate wildfire outcomes for over 26,400 trees.
Researchers at Westlake University have developed a new membrane material that addresses the major obstacle of membrane degradation in anion exchange membrane water electrolyzers. The poly(aryl methylquinuclidinium) membrane shows high performance under demanding operating conditions, enabling scalable industrial manufacturing.
The paper proposes 'transcending natural evolution' by using technology to augment human abilities, bridging the gap between biological and algorithmic iteration. Recent advances in AI, robotics, and bioelectronics are blurring the lines between digital and embodied intelligence.
Researchers at ETH Zurich developed a handheld device that detects acetone in exhaled air to measure fat metabolism. The device provides reliable results comparable to blood tests and has the potential to personalize diets and therapies for metabolic disorders.
A comprehensive survey of the Great Barrier Reef's microbiome reveals over 800,000 microbial genomes, identifying 500 new bacterial species and 300,000 distinct viruses. The study provides insights into the impact of human activities on the reef's health.
Researchers discovered that CRISPR-Cas plays a broader role in bacteria, directing a network of innate immune systems. Over 20 innate defense modules are genomically embedded within type I CRISPR-Cas loci, which are kept under tight transcriptional control by small RNAs.
Researchers have discovered a rich genetic diversity of avocado varieties in Central America, including those grown in Nicaragua, which could help boost sustainable agriculture and commercial varieties. By analyzing DNA from local farmers and examining leaf samples, the team found evidence of ancient migration from South America thousa...
A cohort study of California educators found associations between trihalomethanes in drinking water and increased uterine cancer risk, including with endometrioid tumors. Further investigation is warranted to understand the role of drinking water contaminants as modifiable risk factors for this common gynecologic cancer.
Teenagers and young adults have the highest individual environmental impact from their diets, producing the highest per-capita food-related GHG emissions worldwide. Meanwhile, population ageing is contributing to an increase in global dietary greenhouse gas emissions, primarily due to older people living longer and having fewer children.
Researchers identify a specialized lymphatic network in the brain that enables cerebrospinal fluid drainage, which declines with age but can be restored through intranasal VEGF-C delivery. This discovery provides new insights into brain waste clearance and its link to neurodegenerative disorders.
The discovery of an exomoon in the CD-35 2722 system, orbiting a brown dwarf rather than a planet, challenges our understanding of planetary objects. The exosatellite is estimated to be at least as massive as Jupiter and orbits a highly massive companion, blurring the lines between stars, planets, and moons.
Researchers developed a handheld breath detector that measures acetone levels with laboratory-level accuracy in 90 seconds. The device tracks changes in fat metabolism during various scenarios, including exercise and fasting, providing insights for clinicians to personalize treatments.
A UNIGE study shows that a slight overproduction of tubulin, essential for cell structure, can disrupt tissue architecture and reduce cell viability. Microtubules play a dynamic role in adapting to the cell's changing needs, and excess tubulin makes them abnormally stable.
Researchers found that flies use brain circuitry for spatial navigation to remember where a plume boundary lies and steer back to it. By tracking the edge of an odor plume, flies store a directional memory that allows them to navigate towards the scent source even in turbulent conditions.
A new international study reveals that age plays a significant role in shaping global food-related greenhouse gas emissions. The research found that adolescents and young adults consistently have the highest per-capita dietary greenhouse gas emissions globally, while population aging has become an increasingly important driver of total...
Researchers used machine learning to analyze thousands of automated experiments and accurately predict how new material compositions will respond to heat, identifying the most promising materials. This approach gives scientists a roadmap for developing more durable perovskite solar cells that can withstand real-world operating conditions.
A global study led by NUS Medicine found that Singaporeans have the highest life expectancy and healthy life expectancy, but a growing number of years are spent in poor health. The morbidity gap has widened globally, with people spending more years lived with illness or disability.
A Peking University research team has developed the world's first chip that can match the functioning speed of the human brain. The chip, which operates at 50 MHz and uses in-memory computing, reduces data movement and brings high-quality brain modeling closer to real-time use.
This study found that young, non-Hispanic white women who are physically active and drink heavily are more likely to engage in intentional outdoor tanning. Intentional tanning is associated with increased risk of sunburn and skin cancer, highlighting the need for targeted strategies to reduce this behavior.
Researchers have identified a unique type of melanoma that spreads between catfish in Lake Memphremagog, behaving like parasites. The discovery sheds light on the spread of cancer in wild animals and raises questions about its origin and ecological impact.
Researchers studied mouse tumors and found genetic differences influenced cancer development pathways and stability, suggesting personalized medicine may benefit from genetic background consideration
Scientists have developed a method to synthesize Neosrangcicin A, a complex molecule with potential as a reserve antibiotic. The successful synthesis provides a foundation for altering the natural substance and developing more stable variants.
Researchers at Science Tokyo develop a Ramsey-based magnetometer that overcomes thermal limitations, enabling close-proximity detection of weak biomagnetic signals. The sensor achieves high sensitivity and safe operation near biological tissue.
JMIR Publications is sponsoring the upcoming BioMedEng26 conference to promote biomedical engineering innovation. The journal JMIR Biomedical Engineering will be highlighted during the event, with Dr. Javad Sarvestan discussing its focus on cutting-edge engineering applications and peer-review process.
The review explores various propulsion strategies, navigation algorithms, and on-demand release mechanisms for autonomous microrobots. The authors propose a four-tier hierarchy based on barrier traversal capability, enabling local, systemic, deep tissue, and immune-privileged delivery.
A study identifies curcumin as the natural compound with the most balanced combination of anticancer activity and safety against fibrosarcoma cells. Curcumin, along with berberine, disrupts mitochondrial function and energy metabolism in cancer cells, leading to cellular senescence and death.
A new study reveals that p53 mutations in cancer cells can limit the effectiveness of immunotherapy by manipulating cellular metabolism, specifically through autophagy. Removing these mutant forms of p53 restores mTORC1 activity and reduces autophagy, making tumors more vulnerable to immune attack.
Insilico Medicine has nominated an AI-driven novel compound ISM9528 for pain management, addressing the $100 billion market challenge. The compound targets Target Z and offers a non-opioid treatment approach with superior efficacy and safety profile.
Scientists at UVA have developed a new method to target glioblastoma, the most common and deadly brain cancer, by delivering microRNAs through the brain's natural barrier. The approach shows promise in slowing tumor growth and extending survival in animal models.
A new randomized clinical trial suggests that singing therapy provides greater short-term symptom relief and improved quality of life compared to diaphragmatic breathing exercises for people with supragastric belching. Structured singing therapy also resulted in higher response rates and more enjoyable experiences among patients.
A new study has found that exposure to glyphosate, a widely used herbicide, may increase the chance of giving birth too early. Women with higher levels of glyphosate in their urine samples were more likely to go into spontaneous labor before 37 weeks.
Researchers found that bee venom can improve motor function and cognitive decline in a mouse model of Parkinson's disease when used alongside conventional therapy. The study suggests promising benefits for developing adjunct therapies to improve treatment outcomes.
Researchers at ISTA develop two modeling approaches to represent extremely deformable surfaces more realistically while cutting computational costs. They take inspiration from natural systems like volcanic lava and cake batter to create a wave-based approach, which tackles long-standing graphics problems from a new angle.
A novel cross-modal fusion framework integrates low-altitude drone RSI with ground robot LiDAR-inertial measurement unit (IMU) odometry to create accurate digital models of orchards. The system achieved localization accuracy on the order of a few centimeters, demonstrating robustness to seasonal variations and long-term drift.
Researchers found that brain fluid circulation depends on blood flow in the venous sinuses, and impaired lymphatic vessels lead to accumulated fluids causing pressure buildup. The study opens new avenues for refining diagnosis and improving patient care for patients with IIH.
A new study reveals that despite improvements in access to services through Jordan's Principle, First Nations children still face long-standing inequalities in healthcare. The review highlights the critical role of allied health professionals in navigating the system and calls for improved training and awareness among healthcare workers.
A recent study by the University of Bonn and international partners found that land degradation significantly impacts crop yields worldwide. Reversing 10% of human-made soil damage could increase arable land's food supply by 70 million people.
A groundbreaking study quantified CO2 emissions from acid mine drainage neutralization in metal mining, finding it releases a similar amount of CO2 as conventional copper production. The long-term impact is concerning, as the process can continue for centuries, making it a significant challenge for decarbonizing the industry.
A team of international researchers has successfully demonstrated a breakthrough in detecting satellites and space debris in orbit using repurposed radio telescopes. This technology can increase sensitivity by more than tenfold, enabling the detection of smaller objects at greater distances.
A randomized clinical trial found that ingesting fecal microbes from healthy donors improved sleep efficiency and reduced wake after sleep onset in participants with chronic insomnia. Sleep quality scores also showed significant improvement over two months.
Scientists have developed a method to encapsulate enzymes in a protective molecular cage, enabling efficient and recyclable reactions at high temperatures. This breakthrough has far-reaching implications for sustainable chemical manufacturing and could lead to the creation of new products in industries such as cosmetics.
Research in New Phytologist shows that plant spininess is shaped by browsing mammals past and present, as well as environmental conditions like dry-season length, soil pH, and temperature. Current and extinct large herbivores are key predictors of spiny species prevalence.
Researchers discovered specific microRNAs, including miR-16 and miR-140, which may help detect cancer-related muscle wasting in dogs. The study's findings have implications for human medicine, suggesting a potential new approach for earlier diagnosis and monitoring of cancer-related cachexia.
A US county-level analysis reveals a significant association between high levels of household debt and increased suicide rates during the Great Recession. Suicide rates doubled for men and tripled for adults aged 40–64 years in high-debt counties, highlighting the need for policy interventions targeting mental health impacts.
Research suggests that sports-based interventions may improve motor skills in children with autism spectrum disorder. Martial arts and aquatic training demonstrated the most consistent benefits, particularly in balance and total motor skills. Larger studies are needed to confirm these findings.
Researchers at Japan Advanced Institute of Science and Technology developed a new computational method combining neural networks with Bayesian localization, achieving accurate predictions while reducing computational cost. This breakthrough enables the high-precision analysis of large-scale materials and complex chemical reaction systems.
Researchers developed an AI that navigates ships using human-like decision-making, handling complex situations such as narrow channels and multiple vessels. The AI achieved compliance with maritime traffic rules and demonstrated unexpected behavior like local navigation customs.
A new study in the Canadian Journal of Cardiology predicts that generic semaglutide will dramatically increase cost-effectiveness and health system affordability for patients with type 2 diabetes and high cardiorenal risk. The estimated annual cost of providing GLP-1RAs to all indicated patients would be $3.35 to $5.31 billion at pre-g...
According to new research from the West Health-Gallup Center on Healthcare in America, nearly one in four U.S. workers are currently in a job they want to quit but stay due to health insurance coverage. Women and people with chronic conditions experience higher rates of job lock.
Indigenous Australians gathered whole grasses from the landscape and burned them in a cave for ritual practices dating back 25,000 years. The study found that people selectively targeted specific types of grasses for burning, with over 97% coming from temperate or cool-climate grasses.