Scientists have developed a method to synthesize Neosrangcicin A, a complex molecule with potential as a reserve antibiotic. The successful synthesis provides a foundation for altering the natural substance and developing more stable variants.
The VASC-IMMUNE project aims to understand the interaction between endothelial cells and immune cells in tumors, with a focus on melanoma and glioblastoma. By identifying key factors in vascular-immune crosstalk, researchers hope to develop novel treatments that optimize T cell recruitment and formation of activating immune hubs.
An interdisciplinary team of researchers from Magdeburg has discovered a new mechanism that enables the immune system to eliminate invisible cancer cells. Helper T cells engage scavenger cells, secreting chemical mediators that attract and support their destruction on behalf of cancer cells.
The new 7-Tesla MRI machine will enable researchers to map and measure brain structures with unprecedented precision. The machine, part of the Center for Advanced Medical Engineering, is available for research purposes and will accelerate neuronal research with AI-based algorithms.
Researchers have developed a new sea ice model that can analyze the size and thickness of individual ice floes and their motion in greater detail. This allows for more precise predictions about their behavior, especially in areas where climate change has led to an increase in loose sea ice.
A new AI-based app developed by Otto-von-Guericke-Universität Magdeburg allows individuals with pedophilic tendencies to access initial consultations and remote treatment while maintaining anonymity. The technology, called AnonymPrevent, aims to increase acceptance of preventative treatment against child abuse.
Researchers uncover nitric oxide's dual effects on pathogens: direct destruction and prevention of excessive immune response. This discovery could lead to new treatments for infections and inflammatory diseases.
Researchers are analyzing the emergence and spread of infectious aerosols in human breath to understand why some people spread diseases more easily. The team is developing simulation models to predict aerosol distribution and develop medications that can reduce aerosol formation.
Professor Ullsperger and his team aim to understand the neural mechanisms behind cognitive control and decision-making using new methods, including brain stimulation with focused ultrasound. The research may lead to new therapeutic possibilities for psychiatric disorders such as OCD.
Engineers at Otto-von-Guericke-Universität Magdeburg create turbine blades with integrated drives to optimize flow and reduce stall conditions, leading to increased efficiency and lifespan. This technology aims to combat climate change by harnessing sustainable tidal energy, reducing the need for high-performance materials.
A team of scientists discovered that mast cells orchestrate the recruitment of neutrophils through a molecular mechanism involving tumor necrosis factor. Mast cells position themselves around blood vessels and release TNF, which activates surface proteins on neutrophils, allowing them to migrate into tissues.
Researchers at Otto von Guericke University Magdeburg aim to understand brain cognitive potential, variability, and neurobiological processes that prevent full utilization. The goal is to develop interventions improving cognitive performance in healthy individuals and those with hidden disease processes.
Researchers at Otto-von-Guericke-Universität Magdeburg are using brain research methods to analyze artificial neural networks and improve explainable AI. The Cognitive neuroscience inspired techniques project aims to understand the internal processes of ANNs and identify malfunctions.
A cross-national study found that higher income inequality is associated with more social problems, but economic prosperity has a mitigating effect. The research analyzed data from 40 high-income countries and suggests that social bonds are weaker in countries with greater income gaps.
Researchers call for standardized protocols to enhance reproducibility in behavioral science research. Economists advocate incorporating measurement uncertainty into studies, just like in natural sciences, to identify sources of errors and improve accuracy.
A German study finds that social appreciation and disrespect in daily life significantly vary based on socio-economic factors. Individuals with higher incomes and education levels tend to feel more recognized and respected, whereas the unemployed are at a greater risk of experiencing less recognition and respect.
German experimental economists conducted the largest laboratory experiment in economic research to date, refuting the theory that individuals lack motivation to participate in public goods due to negligible impact. The study found that visibility of mutual benefits is crucial for collective action in large groups. Cooperative decision-...
Engineers developed a novel scanning quantum dot microscopy method that enables the accurate measurement of electrical potentials at molecular resolution. This breakthrough allows for high-resolution images of potential fields, previously unattainable, and opens up possibilities for creating nanostructures via 3D printing.
The DoRIoT project aims to enable statutory regulations and industry standards on data security, reliability, and privacy in the Internet of Things. By developing self-organizing migration of services, companies can operate independently of cloud infrastructure and reduce traffic and reaction time.
Researchers are developing robotic fish surrogates to assess the fish-friendliness of hydroelectric power plants. The RETERO project aims to reduce and eventually eliminate live fish tests, which result in high mortality rates for fish traveling through turbines.