The NIH is conducting a Phase 2 trial to test the safety and efficacy of an anti-CD14 antibody, IC14, in treating hospitalized COVID-19 patients with low blood oxygen. The study aims to determine if treatment with IC14 decreases recovery time and reduces disease severity.
Osaka University researchers used a photostabilizer to modulate fluorescence blinking in biochemical assays, allowing for the detection of a cancer RNA biomarker at ultralow concentrations. The technique increases fluorescence and eliminates blinking, providing a clear means to diagnose diseases in early stages.
A new study identifies non-Th2, or non-atopic childhood asthma, as a distinct disease with early exposure to airborne Benzo[a]pyrene linked to its development. The findings suggest that air pollution is a likely contributor to the most severe form of asthma.
New studies published in The Lancet and The Lancet Public Health suggest the B.1.1.7 variant is more transmissible, with higher viral loads, but no association with increased disease severity or death.
Researchers have created the first patient-derived organoid model for cervical cancer, allowing them to study human papillomavirus (HPV) and its impact on cervical tissue. The model's success holds promise for advancing research into cervical biology and associated diseases.
Researchers found that aged bone marrow niches restrict the function of rejuvenated hematopoietic stem cells, which can lead to leukemia. The study suggests that addressing the influence of an aged niche is crucial for sustaining the function of rejuvenated HSCs.
Researchers at NYU Grossman School of Medicine found that citicoline restored optic nerve signals in rats with glaucoma, reducing vision loss and slowing nerve cell decay. The study suggests a new mechanism for treating the condition, which affects over 60 million people worldwide.
The US Preventive Services Task Force recommends against routine screening for vitamin D deficiency in healthy adults due to insufficient evidence. Individual requirements for vitamin D levels vary, making a one-size-fits-all approach challenging.
A recent study finds that melting Arctic sea-ice is causing severe cold and snowy mid-latitude winters in Europe. The loss of Arctic sea-ice has been implicated with increased open-water and winter evaporation, fueling more extreme snowfall further south across Europe.
Researchers found a significant positive correlation between December sea surface temperature in the Indian Ocean and haze days in January over the Yangtze River Delta region. The study reveals that favorable local meteorological conditions, including increased air temperature and southerly winds, facilitate haze formation.
Researchers at Medical University of Vienna improved liver transplant mortality prediction by adding laboratory parameters to the MELD score, which showed significant benefits in identifying high-risk patients. The study used vWF antigen and CRP levels to assess portal hypertension and inflammatory processes.
Researchers developed a photo-oxygenation catalyst that destabilizes and removes amyloid plaques, enhancing immune system clearance. The treatment significantly reduced amyloid protein in mouse brains, with human brain samples supporting its potential use in humans.
The University of Massachusetts Amherst is collaborating with Big Idea Ventures on a $125 million fund to develop sustainable food products and agricultural innovation. Researchers at UMass will focus on plant-based proteins and their impact on the human microbiome, aiming to create tastier and more economically beneficial products.
Researchers at Ohio State University found COVID-19 virus genetic material persists in dust for up to a month, suggesting it could be used to monitor outbreaks. The study suggests dust monitoring could offer an alternative method to wastewater testing, particularly in high-risk communities.
Researchers developed a fluorescence-based sensor for continuous cortisol detection, overcoming existing laboratory methods. The new sensor showed low levels of detection and reversible response in vitro, paving the way for an implantable sensor for real-time monitoring.
A University of Granada study found that smoking cannabis significantly worsens visual acuity, contrast sensitivity, and glare sensitivity. Notably, over 90% of users believe the drug has no effect on their vision, highlighting a need for awareness-raising campaigns to inform users about the risks.
A new observational study found that suicide numbers remained largely unchanged or declined in the early months of the COVID-19 pandemic in high-income and upper-middle-income countries. However, governments must remain vigilant as the longer-term mental health and economic effects unfold.
Researchers found that a chemical modification of RNA, influenced by diet, plays a key role in polycystic kidney disease. Limiting methionine in the diet may partially control cyst formation, and identifying chemicals that stem Mettl3 activity may lead to new drug treatments.
Hokkaido University researchers have developed a model that explains the causes of past glacial river floods in northern Greenland and predicts future flooding risks. The study reveals that torrential rainfall was the primary driver of the 2016 flood, while warm temperatures were responsible for the 2015 event.
Researchers developed guidelines to promote vaccines on social media, analyzing a grassroots campaign and finding that 78.9% of tweets were anti-vaccine despite the event's intention. The team recommends using personal narratives, partnerships, and inclusivity to create effective pro-vaccination campaigns.
The International Society for Stem Cell Research (ISSCR) has launched a new podcast called The Stem Cell Report with Martin Pera, which delves into the inspiration and stories behind stem cell research. The podcast features interviews with leading researchers and experts in the field.
A recent NIH workshop highlighted the need for further research on post-acute COVID-19, a condition characterized by heterogeneous symptoms and long-term effects. The workshop presented important knowledge gaps in understanding the underlying pathophysiology of PASC.
A study found that 79% of households are willing to pay extra for cropping diversification, valuing agroecosystem services and socio-cultural benefits. The total non-market value of cropping diversification can be up to 47-95% compared to annual market revenues.
Researchers used 3-D printed models to explore fractal-like interior shell patterns in ancient ammonoids. The study suggests that the intricate sutures and septa may have retained more liquid through surface tension, helping the ammonoids fine-tune their buoyancy.
A team of researchers from Ruhr-University Bochum and Sorbonne Université has discovered the significant contribution of small hydrophobic molecules to the energy costs of electrochemical reactions. The study found that these molecules interact with water at interfaces, leading to a crucial role in the chemical reactions.
A study published in PLOS Biology found that human screams communicate multiple emotions beyond fear, including pain, anger, fear, pleasure, sadness, and joy. Researchers used four experiments to investigate the acoustic diversity of scream calls and found that listeners responded more quickly and accurately to non-alarm screams.
Researchers developed an ultrasensitive assay to measure cathepsin B in blood, detecting the biomarker for a range of disease states. This breakthrough aims to improve diagnosis and treatment strategies for conditions such as traumatic brain injury.
A large US study found that physical inactivity is associated with more severe COVID-19 infection and a heightened risk of dying from the disease. Patients who were consistently inactive during the pandemic were more likely to be admitted to hospital, require intensive care, and die than those who met physical activity guidelines.
A recent study has identified two distinct immune profiles in severe asthma patients, which could lead to personalized treatment approaches. The research, conducted by a team of scientists at the University of Pittsburgh and Stanford University, used advanced tools to characterize immune cells within the airways of severe asthma patients.
Researchers at Baylor College of Medicine developed guidelines to select the best deconvolution method for RNA-seq data analysis. They evaluated 11 methods and identified their strengths and weaknesses in various scenarios, providing a benchmark for scientists to choose the optimal method for their needs.
A recent study by University of Georgia researchers found that people are more likely to rely on algorithms for decision-making, even when faced with complex challenges. As the task becomes harder, people prefer algorithm-generated suggestions over human advice or 'wisdom of the crowd', according to the study.
A new study examines the feasibility of ocean alkalinization to simultaneously address global warming and ocean acidification. The research reveals that nearly doubling the carbon-dioxide uptake rate of the Mediterranean Sea after 30 years could mitigate climate change and counteract acidification.
Dr. Jaeger's designation recognizes her high degree of experience with GreenLight Laser Therapy, providing effective relief from BPH symptoms like frequent urination and weak urine flow. The procedure is a minimally invasive outpatient solution with no incisions or impact on sexual function.
Researchers developed a method to grow crystals with reversible phase transitions between 2D and 3D structures, leading to significant changes in electronic conductivity. The alloy's properties can be controlled by temperature, enabling potential applications in novel semiconductor technologies.
A new study highlights scenarios where a rocky planet around a sun-like star could have oxygen in its atmosphere without life. Astronomers say next-generation telescopes need to characterize planetary environments and detect multiple lines of evidence to distinguish false positives from signs of life.
Researchers discovered that humans evolved higher eccrine gland density due to accumulated changes in the hECE18 enhancer region, which drives EN1 expression. This trait is thought to have adapted to early hominins' hot habitats, promoting survival and evolution.
The International Conference on Nuclear Cardiology and Cardiac CT (ICNC-CT) showcases cutting-edge research and clinical applications in cardiovascular imaging. The conference highlights advancements in machine learning, imaging techniques, and artificial intelligence to improve patient care.
A new study verifies the age and origin of a 1.9 million-year-old Homo erectus skull fragment from East Turkana in Kenya. The researchers also found two new, nearly 2-million-year-old hominin specimens at the site, likely the earliest pieces of H. erectus skeleton yet discovered.
Researchers at KIT and Chimie ParisTech/CNRS create light-addressable qubit using europium(III) rare-earth ions, advancing quantum computer development. The molecule's nuclear spin levels can be polarized with light, enabling efficient processing of data in parallel.
Researchers developed a nanostructured fluid that slowly releases cleaning agents to remove over-paintings on street art without damaging the underlying layer. The technique, which uses low-toxicity solvents and biodegradable surfactants, has been tested successfully on laboratory mockups and real pieces of street art.
Researchers have identified a new technique to test the quality of quantum correlations in large systems, reducing resource intensity and increasing noise resilience. By combining two processes, they enable efficient certification of correlations in complex systems.
Researchers at Shinshu University have successfully edited the silk moth's temperature sensor to induce dormancy based on day length, similar to its ancestral species. This breakthrough sheds light on the molecular mechanisms behind environmental adaptation in insects and has significant implications for the sericulture industry.
Scientists at Tokyo University of Science develop biofuel cells that use lactate to generate power for wearable devices. The new design can drive a commercially available activity meter for 1.5 hours using one drop of artificial sweat.
A new study by Cornell University researchers has found a positive association between exposure to televised campaign ads and reported diagnoses of anxiety among U.S. adults. The study analyzed two large national datasets and found that increased ad exposure was linked to higher odds of being diagnosed with anxiety.
Researchers from Niigata University used 3D imaging to analyze the morphology of the human uterine endometrium and adenomyotic lesions. The study reveals a unique plexus network structure in the basal glands, which is detected in all samples regardless of age or menstrual cycle phase.
Researchers argue that limited science literacy and structural constraints make it hard to discern fact from falsehood. Emotion and humor may help address the issue by drawing attention to valuable information and humanizing sources.
UMass Lowell's Kennedy College of Sciences is hosting a free event series showcasing cutting-edge research and educational opportunities. Experts will discuss COVID-19 vaccine development, search for life on Mars, and diversity in the sciences. The series is open to the public and features online events from April 10-16.
Researchers developed a new fluorescent probe, CDgB, that can selectively target the cell membranes of B lymphocytes over T lymphocytes. The probe works by exploiting differences in membrane structures between B and T cells, particularly phospholipid composition and cholesterol content.
A summer camp mindfulness program decreased emotional distress in school-age children and empowered campers and counselors with self-regulation skills. The program also improved counselor management skills and classroom behavior.
Researchers from NIH propose a new method to estimate vaccine efficacy by following original placebo recipients after vaccination, allowing assessment of durability and potential delayed harm. This approach enables timely access to the vaccine for placebo recipients while maintaining unbiased estimates.
A new study on the Northern Star Coral reveals its ability to recover from laboratory-induced stress, shedding light on coral resilience. Researchers found that coral with algal symbionts recovered their mucus microbiomes more consistently and quickly.
A study by the University of Malaga found that children spending more time on screens are more likely to consume less healthy foods and more sweets. Parents' education level also plays a role, with lower levels associated with poorer dietary habits in children.
Researchers at Skoltech's Space Center have developed an algorithm to measure the geomagnetic field using CubeSats in a tetrahedral orbital formation. The system uses Kriging interpolation to predict magnetic field values, enabling improved attitude control and station-keeping systems.
A new study found that spotted salamanders' egg mass coloration is influenced by two opposing evolutionary forces: genetic drift and balancing selection. In small populations, genetic drift drives changes in morph frequencies, while balancing selection helps preserve multiple traits.
A new study published in Translational Psychiatry reveals that individuals with high genetic predisposition to schizophrenia are disproportionately affected by cannabis use, experiencing a 60% higher risk of psychotic experiences. Cannabis users, compared to non-users, have higher rates of psychotic experiences across the board.
Researchers at Ohio State University suggest that an oral drug currently used to treat neuromuscular diseases could help prevent a common form of skin cancer caused by UVB radiation. The study found that the neurotransmitter dopamine can stop the development and progression of certain UVB-induced precancerous squamous skin cancers.
A study by Kaunas University of Technology reveals the benefits of telehealth, including accessibility, convenience, and cost-saving. However, organizational and individual barriers, such as lack of digital training and reimbursement issues, hinder its widespread adoption.
A six-week Basketball Mathematics program improved math motivation, self-determination, and mastery among 756 Danish schoolchildren. The study found that students who participated in the program showed a 16% increase in math motivation and a 14% rise in self-determination compared to those who did not participate.
A global analysis of protected areas found that only 30% of forest loss in protected areas has been prevented, highlighting the need for improved enforcement and targeted conservation efforts. Protecting forests is crucial for sustainability, and scrutinizing protected areas across the globe can help direct efforts to the right places.
A recent study from Spain suggests that deficit irrigation can be a sustainable practice for almond production in the long term. Despite significant investments and water scarcity, the study found that trees subjected to severe deficit irrigation maintained stable productivity over six years.