University of Connecticut researchers found that Rett syndrome symptoms are caused by a lack of dopamine in the carotid body, leading to unstable breathing. This discovery may lead to new treatments for Rett syndrome and other diseases involving dopamine imbalance.
A study led by Jennifer Fields found that collagen peptide supplements improved bone turnover in female runners, increasing markers of bone formation and decreasing inflammation. This pilot study suggests that four weeks of supplementation is sufficient to move biomarkers towards more favorable bone health.
Researchers found that watching positive aging videos on TikTok increased women's positive emotions about aging, boosted their confidence in aging well, and even changed their attitudes towards older people. The study suggests that having a positive aging role model can be enough to change one's own thinking.
Researchers developed a framework to analyze high-frequency satellite data and measure the vital signs of global cities. The Urban Pulse can identify areas of unsustainable sprawl and provide an early warning system for policymakers and citizens. This tool has the potential to revolutionize how people interact with their cities.
Tidal wetlands are critical ecosystems that support biodiversity and protect against flooding, but their loss is accelerating due to human development and climate change. A new study using satellite data shows that extreme weather events are driving this acceleration, with tidal wetland areas shrinking by 7.5% in the US since 1985.
A University of Connecticut study used genomic data to predict which guide dogs are likely to succeed, revealing a better predictor than traditional evaluations for at least 11 traits. This breakthrough could inform breeding values and lead to improvements in the population over time.
Researchers from UConn and Yale have developed a compact, solar-powered water disinfection system that combines existing methods. The system effectively utilizes photosensitizers to kill viruses and bacteria in water, providing a clear indication of when the water is safe to drink.
A novel study found that using a topical testosterone gel in conjunction with exercise can selectively reduce visceral fat in older women who have suffered a hip fracture. This reduction in visceral fat has beneficial health impacts, including decreased risk of diabetes and cardiovascular disease.
Teens are getting significantly less sleep, with over 50% reporting less than 5 hours per night, a rise from 2007 when it was around 30%. This short sleep is linked to emotional regulation issues, poor academic performance, and increased risks for obesity and diabetes.
Researchers discover that seaweed farms drive a climate-friendly feedback by producing alkalinity, which shifts the chemistry of the water and removes CO2. The process is more permanent than previously thought, making seaweed farms an ideal system for carbon sequestration.
A team of researchers at UConn has developed a novel line of bovine embryonic stem cells, which have significant potential for lab-grown meat and human tissue replacement. The cells can be induced into muscle and fat cells to produce meat products and also have applications in medical research and disease-resistant cattle development.
A recent study found that adding manganese to soil can lower plant-available nitrogen, reducing nitrous oxide emissions and nitrate leaching into waterways. Manganese also reduced the expression of genes involved in nitrogen cycling.
A study by University of Connecticut researchers found that missionaries consistently draw on the same language toolkit to describe their experiences abroad and difficulties returning home. They used metaphors, personification of God, and biblical vernacular to make sense of their transitions.
A new UConn study reveals how political donations from large landowners in the Amazon contribute to soybean farming and deforestation. The research found that campaign donations to winning politicians lead to increased development of soybean production, but also exacerbates land inequality in the region.
Research found that the federal earned income tax credit decreases rates of intimate partner violence, particularly among low-educated and unmarried women. The study revealed a 9.73% decrease in physical and sexual violence and a 21% decline in counts of such violence.
A team of researchers, led by Lijing Wang, used field data and modeling to explore the factors influencing mountain headwater streams. They found that evergreen forests act as a buffer for excessive snowmelt flow, while subsurface conditions like permeability control streamflow dynamics.
A new method of gene editing allows for the efficient production of non-GMO, genome-edited plants without introducing foreign DNA. The technique uses Agrobacterium-mediated transient expression to enable genome editing in a transgene-free manner.
Researchers studied beaver ponds' effect on groundwater recharge, finding a 10-fold increase in recharging water. They also explored evapotranspiration and found it can reduce recharge in certain soil structures. The study highlights the need for comprehensive analysis of beaver-induced changes to understand their impact on ecosystems.
Researchers developed an AI-driven framework to predict which plant species are most likely to become invasive before they even arrive in a new location. The methodology combines decades of ecological data with machine learning methods to identify high-risk species.
Researchers at the University of Connecticut have developed two fast tests for early markers of Alzheimer's disease using CRISPR technology. The tests recognize microRNA molecules associated with Alzheimer's, allowing for quick identification in doctor's offices.
Research finds that commercial wind energy installations lead to a significant 3% increase in community home values after becoming operational. This effect is strongly correlated with the size of the energy project and positive impacts on school district revenues and per-pupil expenditures.
Researchers developed a new diagnostic test, CAARRD, to detect ribonucleic acid (RNA) at room temperature, increasing sensitivity and reducing complexity. The test uses special 'anti-tag' CRISPR sequences to block the activity of the Cas13a enzyme, allowing for faster and more affordable detection of viral RNAs such as HIV.
Researchers reexamined the genetic conflict in the maternal-fetal interface, finding a delicate balance of cooperation and competition that ensures successful pregnancy. The study sheds light on pregnancy complications like placenta accreta and preeclampsia, and may have broader implications for cancer metastasis.
Researchers investigated why harbor seals get sick from influenza, while gray seals don't. They found no difference in cytokine profiles between infected and non-infected gray seal pups.
A new study from UConn researcher Amanda Cooper provides suggestions for families to communicate effectively with loved ones living with dementia while upholding their personhood. The study recommends reminiscing about past experiences, expressing gratitude, and adjusting communication approaches based on the individual's current capab...
A new UConn study finds that composting programs can reduce organic waste in landfills by 30% per household per week. However, the cost of implementing and maintaining these programs is often too high, making them unfeasible for many municipalities.
Researchers have developed a new model to account for three-dimensional animal movement, addressing the challenge of studying animals that move up or down in space. The model provides accurate measures of 3D animal motion, including topography and Earth's curvature.
Researchers discovered that our bodies add sugars to RNA, shielding it from the immune system. This 'sugarcoating' prevents inflammation and helps clean up dead cells.
A new study finds that partisan hostility is a key driver of protest participation in the US, exceeding concern for actual issues. Hostility towards opposing parties was a major factor in all three analyzed movements, with Americans in highly partisan counties more likely to protest.
A new study has developed a novel tool to assess the impact of parasites on horse skin and coat conditions. Horses with higher parasitic loads were found to have worse coat conditions, which can provide insights into parasite management.
A new study identified key risk factors associated with non-fatal overdoses, including polysubstance use patterns, socioeconomic challenges, and lack of access to harm reduction services. The study found nearly half of participants had experienced a non-fatal overdose in their lifetime, significantly higher than previous rates.
A new study found commercially available body-cooling garments provide significant protection against extreme heat for laborers. Participants wearing cooling garments had lower internal temperatures and improved performance in tasks compared to those without, making these garments a valuable resource in hot environments.
A JAMA Psychiatry study recommends increasing contingency management incentives to improve opioid addiction recovery outcomes. The research team suggests using evidence-based incentive amounts, such as $128 per week for vouchers or $55 per week for prizes over 12 weeks, to effectively reduce stimulant and/or opioid use.
Researchers developed a blood-based proteomic score to predict healthy aging and age-related diseases. A lower score is associated with higher mortality and disease risk, offering a powerful tool for understanding biological aging.
A study published in the Proceedings of the National Academy of Sciences reveals that sports fans' emotional arousal peaks during pre-game rituals, not during the game itself. Physiological data from a Brazilian soccer fan club shows sustained arousal levels comparable to the game.
Researchers have demonstrated that a novel protein-based nanoparticle can stabilize and deliver mRNA vaccines, making them more effective against Infectious Bronchitis Virus in chickens. The vaccine shows a 1000-times increase in antibodies and boosts immune cell activity.
Scientists have found that oceanic anaerobic respiration produces sulfur species, forming pyrite or 'fool's gold', which helps buffer the alkalinity of water and prevent acidification. This process has a stabilizing effect on the ocean, playing a significant role in preserving its alkalinity for millions of years.
A large randomized clinical trial found that testosterone gel did not improve long-distance mobility outcomes for older women after a hip fracture. Supervised exercise, however, showed significant functional improvements and enhanced mobility.
A protein link between brain diseases and leaky blood vessels reveals that endothelial cell dysfunction plays a crucial role in the progression of neurodegenerative diseases. The study found that reduced TDP-43 levels lead to gaps in blood vessel walls, allowing toxic molecules to enter the brain.
A new global clinical trial has demonstrated the benefits of an investigational medication called brensocatib, a DPP-1 inhibitor, in improving bronchiectasis patients' quality of life. The study showed that nearly half of patients remained exacerbation-free one year later and experienced significant improvements in lung function.
A UConn clinical trial confirms walnuts improve colonic health by reducing systemic inflammation and increasing the production of potent anti-inflammatory molecules called urolithins. Elevated urolithin A levels correlated with reduced colon cancer risk, particularly in obese patients.
A study found that people with migraines and other headaches have increased levels of visual cortex excitability compared to healthy individuals. This indicates that existing medications targeting visual cortex excitability may be useful for this population.
Researchers found that people's activity patterns and visit frequency at healthy food sources are stronger predictors of obesity-related cancer risk than location-based approaches. The study used GPS data and obesity-related cancer mortality data to analyze the relationship between food shopping habits and health outcomes.
Researchers developed a method that uses high-resolution satellite imagery and deep machine learning to double the mapped infrastructure of Alaska, more accurately projecting economic risks associated with permafrost thaw. The new model nearly doubles the amount of information available for Alaska on OpenStreetMap.
A team of UConn researchers found that biochar application improves soil microbial biomass carbon by approximately 21%, supporting the functioning of vital microorganisms. Biochar provides essential nutrients and a habitat for microbes, especially in nutrient-deficient soil or soil with suboptimal pH.
Researchers from UConn School of Medicine reveal a novel pathway in cellular dysfunction contributing to neurodegenerative diseases like Alzheimer's and ALS. They discovered that endothelial cells, the inner lining of blood vessels, play a critical role in neurodegeneration by disrupting the blood-brain barrier's protection.
Researchers have identified a small molecule that can successfully disable the virus' mechanisms, reducing viral particles by 1,000 times. The discovery could lead to effective preventative treatments and applications for human anti-viral drug development.
A study found that high school athletes have significant gaps in their general and sports-specific nutrition knowledge. They often rely on social media for information, which can be inaccurate and misleading. The researchers recommend more general and sports-specific nutrition education to empower these adolescent athletes.
Dr. Eric Levine's lab at UConn School of Medicine has been awarded $400,000 to study the genetic pathways of autism spectrum disorders using patient-derived human neurons. The team aims to identify genes and brain cell behavior that may cause these disorders, with potential applications for gene therapy.
Scientists developed a method to detail the influence of plants on global water movement, using phylogenetic tests and machine learning techniques. This approach can impute trait data for 55,000 tree species, improving modeling accuracy and providing a starting point for more detailed vegetation models.