The spin states of myoglobin heme iron in aqueous solutions at room temperature were investigated using nitrogen K-edge X-ray absorption spectroscopy. The study found spin equilibriums between different states in deoxymyoglobin and metmyoglobin.
Researchers evaluated biological age using six internationally recognized proteomic aging clocks, finding a reduction in predicted biological age among patients treated with rentosertib. The drug also showed promising dose-dependent reversal of Forced Vital Capacity (FVC), a measure of lung function declining with age.
A fluorinated imine additive improves graphite anode stability through a LiF-rich protective layer, enhancing lithium-ion transport and long-term battery stability. The additive retains 89.4% and 95.6% of maximum capacities after 1,000 cycles, outperforming additive-free cells.
A simple blending strategy enables reversible fluorescence in block copolymers, allowing visualization of mechanical stress without altering material properties. The approach preserves mechanical properties and offers a practical route for stress-sensing functions in existing polymer materials.
Researchers at the Center for Genomic Regulation in Ukraine describe a decentralized, cloud-based computing model and a train-the-trainer structure as key principles for resilient scientific capacity. The approach has been successful in producing trained researchers and has implications for protecting science during wartime.
The team successfully grew single-crystalline polar wurtzite NbAlN thin films on GaN substrates, preserving the wurtzite crystal structure and metal polarity. This discovery expands the options for designing carrier density in GaN heterostructures, offering a new family of transition-metal-containing polar nitride semiconductors.
Researchers at Nagoya University have developed a method to detect hidden matter around black holes by analyzing changes in ringdown waves. The study found that hidden matter affects ringdown differently depending on its pressure arrangement around the black hole.
A study found that CADD522 strengthened bones in post-menopausal mice while reducing body fat and reversing metabolic changes linked to menopause. The treatment also appeared to reverse menopause-related changes in fatty acids and lipid abnormalities.
Researchers developed a low-temperature steam-assisted process to create durable, conductive spinel coatings on magnesium alloys for harsh acidic environments. The coating achieved ultralow corrosion current density and high sheet resistance, making it suitable for next-generation energy storage and conversion technologies.
Researchers have discovered a stem cell that contributes to lumbar spinal stenosis, a condition characterized by enlarged ligaments and nerve compression. The stem cell's hyperactivity may lead to the development of new treatment options, including drugs used to manage high blood pressure.
A new study reveals that inhibitory brain circuits can suppress adult glioma growth by reducing calcium activity inside tumor cells. Inhibitory neurons form synaptic contacts with glioma cells and reduce tumor cell proliferation and survival in preclinical models.
University of California, Davis researchers successfully synthesized new compounds with reduced hallucinogenic and cardiotoxic effects, identifying one compound with antipsychotic-like effects. By systematically deconstructing LSD, they uncovered the importance of the phenethylamine-like traits in producing hallucinogenic effects.
Researchers found strong similarities in small-scale structural properties and gene expression patterns between humans and macaques, but more differences in large-scale connections. Chimpanzees occupy an intermediate position between macaques and humans, with brain systems showing reorganization in sensory, motor, and internal informat...
A new study reveals that early humans' unique heel-strike walking style allowed for efficient foraging strategies like hunting and gathering, but came at the cost of higher impact forces on bones and joints. This adaptation may have required later anatomical changes to enable safe and consistent walking.
Research suggests that deep sleep strengthens resilience to stressful situations in mice by reorganizing brain activity in the prelimbic cortex. The study found that mice who experienced more deep sleep were better able to cope with stressful social situations.
A recent GEOMAR study found that climate change can trigger cascading natural hazards in the Arctic. The research team investigated an earthquake that triggered a rock avalanche on Jan Mayen island, revealing the devastating impact of permafrost degradation on the region's slopes and glaciers.
Research from Austria and Ireland shows that nicotine addiction remains a major health concern, with vaping and smoking increasing among children and young people. The studies found that smoking has declined, but vaping has risen, particularly among those under 18, and that people are taking up smoking at a younger age. The findings hi...
A prospective cohort study found that adults with hemoglobin levels 1 to 3 g/dL above the World Health Organization's anemia thresholds had lower mortality compared to those with levels below and above this range. The study suggests that further investigation of borderline anemia is warranted.
A new study found that weight loss injection semaglutide may reduce asthma attacks by up to 40% in people with airways diseases like asthma and COPD. Semaglutide also led to a 20% reduction in COPD flare-ups.
Teenagers from lower-income households are more likely to have eating disorders, contrary to common stereotypes. The study found that family income showed the strongest correlation, with two-thirds of studies indicating that lower-income families were more likely to have eating disorder symptoms.