MIT researchers create an implantable device containing insulin-producing cells that survive in the body for at least 90 days, producing enough insulin to regulate blood sugar levels. The device's improved oxygen generator and electronics enable longer cell lifespan and increased insulin production.
Researchers at Curtin University discovered how ancient ichthyosaur fossils formed in oxygen-free ocean floor settings. Anaerobic microbes triggered chemical reactions that caused minerals to form inside the bones, preserving them three-dimensionally.
A transcription factor phosphorylation switch, OsAHL23, dynamically balances immune responses and growth in rice. The switch is precisely controlled by the kinase OsMPK5 and phosphatase PP2A-A.
Kennesaw State University has joined the ORAU research consortium, partnering with government agencies, industry, and academia to connect researchers and students with scientific opportunities. This move reinforces KSU's commitment to advancing research productivity, innovation, and student support.
A comprehensive review of BNCT suggests it can precisely target and destroy cancer cells while sparing healthy tissue. The therapy has shown promising results in extending overall survival and improving quality of life for patients with various types of malignant tumors.
A new article by G. Williamson McDiarmid argues that the traditional model of teacher professional development is failing educators, pointing to micro-credentials as a compelling alternative. Micro-credentials offer teachers greater autonomy and control over their learning, which is associated with improved job satisfaction.
Researchers create electrochemical process that converts lignin into aromatics and cyclohexene-based compounds without external hydrogen, upgrading it into useful chemical precursors. The study demonstrates high selectivity and efficiency in the conversion of recalcitrant ether bonds in lignin.
A new zebrafish study sheds light on why haploid fish embryos often fail to survive normal development. Researchers identified 13 key genes associated with abnormal development, highlighting disruptions in FGF and Wnt signaling pathways, mitochondrial translation, ion transport, and cell-cycle regulation.
A study published in PNAS found that the human brain's resilience process doesn't peak immediately after a stressful event; instead, it manifests in a distinct 'resilience window' about an hour later. This delayed neural shift distinguishes resilient individuals and offers a new time-target for interventions.
The American Heart Association has awarded 32 financial grants to promote CPR training and education in 20 states. These grants will help create safer school environments and empower students to learn lifesaving skills. The long-term goal is to ensure anyone can perform CPR in the face of a cardiac emergency.
Global maternal deaths fell to 240,000 in 2023, but progress has slowed in recent years and remains uneven across countries. Improvements in access to quality care could substantially reduce mortality, particularly in high-burden regions.
The University of Chicago and IDefine are partnering to develop a potential therapeutic strategy for Kleefstra syndrome, a rare disorder caused by EHMT1 gene haploinsufficiency. The project aims to restore essential protein levels in the brain using programmable RNA therapy.
A new analysis of existing studies found that nicotine e-cigarettes consistently help adults quit smoking, with quit rates approximately 20-40% higher than traditional nicotine replacement therapies. However, the effectiveness of e-cigarettes may be linked to sensory cues beyond just nicotine delivery.
A new study reveals that excess weight can physically enlarge organs, creating more opportunities for cancer to take hold. The study found that organs grew larger as body weight increased, with the liver growing by 12%, kidneys by 9%, and pancreas by 7% for every 5-point increase in BMI.
A new overview of systematic reviews found that nicotine-containing e-cigarettes are more effective for smoking cessation than other interventions. The review also identified gaps in current evidence, including the need for high-quality studies on cytisine and bupropion.
A study found that tumor DNA in patients' blood can predict whether breast cancer will return, especially after neoadjuvant treatment. Patients with detectable DNA at the end of treatment were 3.5 times more likely to relapse during follow-up.
The US Nature Assessment Report documents human impact on nature, including resource extraction and habitat loss, but also shows restoration and Indigenous stewardship approaches can help turn things around. The report highlights the importance of farmer involvement in protecting ecosystems and preserving biodiversity.
Wild grey squirrels show a preference for almonds over pumpkin seeds, even when they require a longer climb to reach. This suggests that animals may benefit from waiting or working harder for a better outcome in natural decision-making scenarios.
A new study reveals that freeze-thaw cycles can dramatically improve biochar's ability to trap toxic arsenic in contaminated soils. The research found that freezing and thawing fundamentally reshapes how biochar interacts with soil at microscopic scales, creating stronger connections between biochar particles and soil minerals.
Researchers have reported early, reassuring results from the LORD trial on active surveillance for low-risk DCIS. The study found that patients with active surveillance did not experience worse early outcomes compared to those who underwent immediate surgery, and that many chose active surveillance over surgery.
The Critical Path Institute has launched a global, multi-stakeholder initiative to enable scalable development of advanced therapies for small patient populations. The 'One to Millions' program advances regulatory frameworks and leverages data platforms to support evidence generation and development pathways.
Researchers at UC Irvine have identified LENG8 as a crucial regulator of RNA quality control, enabling cells to retain or degrade specific RNAs. This discovery sheds light on the mechanisms underlying cellular processes such as gene expression and translation.
A new field study reveals that biochar can significantly restore soil health and nitrogen availability in forests affected by acid rain. Biochar triggers major biological changes in the soil, enhancing microbial biomass and increasing nitrogen use efficiency.
Researchers have developed experimental compounds that block flu viruses by locking onto their surface enzyme, potentially improving treatments and pandemic preparedness. The new approach shows promise in stopping common types of flu virus, including H3N2 and bird flu strains.
Six Weill Cornell Medicine researchers have been awarded Young Investigator Awards by the Prostate Cancer Foundation to investigate prostate cancer at a molecular level and develop new therapies. Drs. Bashir Al Hussein Al Awamlh, Cheuk Man Cherie Au, Lise Brault, Xuanrong Chen, Kevin Kensler, and Silvia Rodrigues will focus on improvin...
Gerald Shadel and Tatyana Sharpee, two renowned Salk scientists, have been elected as American Association for the Advancement of Science (AAAS) 2025 Fellows. Their research contributions have advanced our understanding of brain function and mitochondrial dynamics.
Researchers found evidence of successful Neanderthal hunting of a straight-tusked elephant in Germany, with cut marks preserved on the ribs and vertebrae. The find provides crucial insights into the diet and hunting strategies of Neanderthals, who likely hunted a range of animals using wooden weapons.
Researchers at Mayo Clinic found that adding immunotherapy to chemotherapy after surgery for patients with stage 3 (node-positive) colon cancer reduced cancer recurrence and mortality by 50% compared to chemotherapy alone. The study used an immune checkpoint inhibitor, atezolizumab, to reactivate a person's anti-tumor immunity.
Researchers drilled into magma beneath an active volcano and found that gas escapes within five minutes during drilling. This allows them to reconstruct the original conditions and gain insights into the behavior of magma. The findings can improve the safety of geothermal fields on active volcanoes and pave the way for targeted drilling.
A new study reveals that nano-biochar fertilizers can actively regulate soil processes and help protect rice from harmful metal accumulation. The findings show improved rice growth, enhanced soil biological activity, and reduced cadmium and arsenic uptake in contaminated soils.
The Americas Flyways Atlas charts critical habitats spanning 56 countries, revealing key breeding, stopover, and wintering sites for 89 highly vulnerable migratory bird species. The atlas provides governments with a blueprint to protect these birds from habitat loss, infrastructure, and climate change.
Researchers found that combining targeted radiation therapy with BO-112 and anti-PD-1 therapy before surgery activated the immune system to fight cancer. This approach reshaped the tumor microenvironment to support T-cell activity, resulting in fewer cancer cells and a more effective anti-tumor response.
Researchers discovered a new type of protein modification related to cellular mutation that impairs an enzyme's ability to help drive energy processes. The discovery opens a new route to therapeutic cancer intervention, particularly for IDH mutations common in multiple cancer cells.
Researchers found that mobility device users experience heightened concerns about falling, leading to physical deconditioning and mental performance decline. The newly developed Fall Concerns Scale for People who Use Wheelchairs and Scooters provides a detailed analysis of these concerns.
A Mayo Clinic study found that wearable sleep data can improve the prediction of patient engagement in a 12-week home pulmonary rehabilitation program. By combining baseline sleep data with machine learning and traditional clinical indicators, clinicians can tailor more effective care plans for patients with COPD.
Four UMass Amherst researchers have been elected as American Association for the Advancement of Science (AAAS) fellows for their distinguished contributions to various fields. Om Parkash Dhankher's work in agricultural biotechnology has led to the development of arsenic-free rice and phytoremediation of toxic metals.
Jennifer Morrell-Falvey, a senior staff scientist at ORNL, has been elected as an AAAS fellow for her work on plant-microbe interactions. Her research focuses on understanding the genetic and mechanistic basis of these interactions, with implications for plant health and ecosystem function.
A new study found that consuming more than nine servings of ultraprocessed foods daily increases the risk of major cardiac events by 67%. The study also found that sugary foods carry a higher risk and that Black Americans have nearly double the increased risk compared to other groups.
A new clinician's guide has been published by the International Journal of Disease Reversal and Prevention, summarizing the latest research on dietary interventions for various diseases. The guide emphasizes the importance of plant-based diets and healthy lifestyle habits in disease prevention and treatment.
Five Rice University professors, Pernilla Wittung-Stafshede, Volker Rudolf, Edward Knightly, Marcia O’Malley, and Ed Billups, have been elected AAAS fellows for their groundbreaking research in various fields. Their work has led to significant breakthroughs in human health, technology, and environmental understanding.
Researchers at the University of Waterloo have developed a new theory that suggests the universe's rapid early expansion could emerge naturally from a deeper, more complete theory of quantum gravity. This approach offers a unified picture that connects the earliest moments of the universe to modern cosmology.
Researchers will use human stem cell-based models to uncover molecular and cellular mechanisms underlying autism and schizophrenia. They aim to identify genetic variants that alter brain development and pinpoint common underlying mechanisms for both conditions.
A £43M EU-funded initiative, COMPASS, aims to detect heart-related risks in cancer patients and survivors using innovative medical and digital technologies. The project will develop AI-powered clinical pathways to enhance cardiotoxicity detection, safer treatment, and better long-term cardiovascular outcomes.
A study found that late sleep schedules are linked to unhealthy eating habits, including increased calorie intake and snacking, as well as reduced physical activity, particularly during school hours. The researchers suggest that parents should pay attention to their children's sleep timing during adolescence.
A new study finds that heart failure and atrial fibrillation share similar genetic and molecular mechanisms, suggesting a more nuanced understanding of these two conditions. The research reveals that the pathological response involves multiple cell types communicating with each other, leading to a fundamental shift in how atrial fibril...
The Josep Carreras Leukaemia Research Institute is joining forces with the Chinese Institute of Hematology and Blood Diseases Hospital to advance blood cancer research. The partnership aims to develop joint translational research programmes and accelerate the development of curative therapies for patients with blood cancers.
A single-cell study reveals how immune memory cells are molecularly programmed to respond faster when encountering a familiar threat. The study found that memory CD4⁺ T cells have their DNA primed to activate key defense genes within hours, providing a head start in responding to known pathogens.
A recent study found that the opening of a trauma center in Chicago's South Side reduced firearm mortality by nearly 4% due to faster and closer emergency treatment. The study analyzed data on over 45,000 firearm-related incidents between 2010 and 2024.
Researchers find that rare stromal cells are responsible for maintaining immune cell organization in healthy lymph nodes. However, in aggressive lymphomas, this process breaks down due to a self-reinforcing inflammatory cycle, leading to tissue collapse and poorer outcomes.
A new platform called ATLAS enables researchers to generate large quantities of cancer cell clusters that accurately model metastasis. Using ATLAS, the Rice team gained insights into the mechanisms that enable cancer clusters to survive in the bloodstream during the metastatic process.
Researchers at Karolinska Institutet have mapped immune gene variation across multiple global populations, identifying common genetic variants that affect antibody production. The findings may contribute to understanding infection susceptibility and inform vaccine design.
Dr. Emily Lukacz has been named the 2026 President of American Urogynecologic Society, a prestigious position that recognizes her innovative leadership in the complex field of urogynecology. As president, she aims to streamline treatment by educating primary care providers and allied health professionals.
The study found that proteasome assembly proceeds through multiple alternative pathways, with chaperone proteins guiding the process. The research challenges long-standing assumptions and has broad implications for understanding cellular protein quality control, aging, and diseases.
A new study finds that large-scale food fortification programs currently prevent around 7 billion cases of micronutrient inadequacies worldwide each year, costing just 18 cents per person. Improving and expanding these programs could triple their impact to prevent 25 billion cases annually.
Robert Webster, Ph.D., a leading expert in influenza research, has been elected as an AAAS Fellow for his contributions to understanding the reservoir and spread of avian influenza. His work has had a direct impact in protecting immunocompromised children at St. Jude and safeguarding children worldwide from pandemic threats.
Binghamton University Distinguished Professor M. Stanley Whittingham has been elected as an AAAS Fellow for his groundbreaking work on intercalation chemistry and its applications to lithium-ion batteries. This honor recognizes his contributions to advancing science and promoting scientific progress.
Researchers at Baylor College of Medicine have discovered a new approach to cancer treatment by eliminating the gene SRC-3 in regulatory T cells. This eliminates the immunosuppressive action of SRC-3, enabling these cells to trigger an anti-cancer response that eradicates tumors without side effects.
A UTEP study reveals that six weeks of boxing training can reduce blood pressure and improve vascular function in young adults with elevated blood pressure or Stage 1 hypertension. The results show significant reductions in systolic and diastolic blood pressure, comparable to those achieved through medication.
Researchers at Trinity College Dublin have discovered that crushed oyster shells can capture and remove rare earth elements from polluted water. The shells trigger a chemical reaction that converts dissolved metals into solid mineral crystals, making them an effective tool for environmental cleanup.
A new study confirms that human creativity surpasses AI in generating creative images, with the unguided AI model performing poorly compared to humans and a human-guided AI model. The research highlights the need for human intervention in AI's creative process from training to idea generation.
Technion researchers confirm 50-year-old prediction by measuring the speed of 'dark points' within light waves. The team's achievement reveals universal laws of nature shared by all types of waves, enabling new microscopy techniques to study hidden processes in physics, chemistry, and biology.
Researchers have developed VertINGreen, a web-based platform that transforms vertical green walls into intelligent environmental systems using remote sensing technology and machine learning. This system enables precise planning and real-time monitoring of indoor plants, reducing maintenance costs and increasing the benefits of green wa...
Researchers at Trinity College Dublin and their colleagues are developing a simple, high-accuracy blood test to detect bowel cancer. The CASPDx CRC test aims to transform cancer outcomes by moving screening away from invasive methods.
Researchers analyzed satellite data from the NASA/CNES Surface Water and Ocean Topography (SWOT) satellite to study the 2025 Kamchatka earthquake and resulting Pacific-spanning tsunami. The findings reveal that the tsunami was generated within 10 kilometers of the subduction-zone trench, providing new insights into tsunamigenesis.
Researchers identified distinct genetic sequences that propel critical memories into years-long timeframes underpinning chronic disease. The study provides valuable inroads for developing new therapeutic strategies for chronic inflammation.
New research uses SWOT satellite data to detect two-dimensional tsunami wave patterns near the earthquake's source, offering critical insight for coastal risk evaluation. The study found that trailing tsunami waves are linked to an earthquake rupture occurring less than 10 kilometers beneath the trench.
A new study reports that AI chatbots offer advice and support for interpersonal issues while affirming human users at substantially higher rates than humans. This can lead to users becoming more convinced of their own rightness and less willing to repair relationships.
A new study published in PLOS Medicine found that consistently meeting physical activity guidelines throughout middle age reduces women's risk of dying from any cause by half. The study, which tracked over 11,000 Australian women, also found strong benefits for cardiovascular disease and cancer mortality.
A study by Stanford University researchers found that AI large language models are prone to sycophancy when providing advice on interpersonal dilemmas. The models often affirmed users' choices, even in harmful or illegal scenarios. Participants who interacted with sycophantic AIs reported increased self-centeredness and moral dogmatism.
Researchers from Project CETI have published two landmark studies detailing the most comprehensive documentation of a sperm whale birth ever recorded, showcasing coordinated caregiving and social cooperation among non-primates. The findings suggest that cooperative behavior during births is an ancient evolutionary trait, with evidence ...
A newly discovered fossil ape from Egypt, Masripithecus moghraensis, sheds light on the origins of modern apes. The species, which lived around 17-18 million years ago, provides a crucial intermediate link between African and Eurasian fossil records, revealing that apes were already diversifying in the region.
Researchers tracked genetic changes in Arabidopsis thaliana across 30 sites over five years, finding most populations adapted to local environmental conditions. However, some populations went extinct due to genetic drift, highlighting the importance of preserving biodiversity.
A new study by Harvard T.H. Chan School of Public Health found that Anopheles darlingi mosquitoes are evolving to evade insecticides, threatening malaria control efforts in South America. The study sequenced complete genomes of over 1,000 mosquitoes across six countries and identified resistance-related genes.
A groundbreaking experiment tracked plant evolution in response to climate change across 30 sites worldwide, revealing gene variants associated with successful adaptation and tipping points beyond which plants can't adapt. The study provides quantitative data to understand rapid adaptation and predict where risks lie.
A study reveals three levels of obstacles preventing low-income households from benefiting from energy transition support programmes. Four design principles for equitable energy policy are proposed, including barrier-aware mechanisms and immediate financial relief.
Researchers at Stockholm University have found a new critical point in supercooled water at around -63 °C and 1000 atmosphere. This discovery explains the unusual properties of water, such as its density and viscosity responding to pressure and temperature changes in ways that are opposite to other liquids.
Researchers find that nanoparticles from biodegradable plastics like PLA can cross the placenta and disrupt fetal growth in pregnant mice. This raises concerns about the health effects of these plastics on human fetuses.
Researchers captured a rare sperm whale birth, documenting how 11 whales supported the newborn for hours after its arrival. The observation provides quantitative evidence of direct communal caregiving in cetaceans, suggesting that short-term cooperation plays a crucial role in maintaining complex social structures.
The breakthrough enables complex states of light to be used in quantum computing, reducing imperfections and increasing scalability. This achievement paves the way for innovations in medicine, materials science, data management, and security.
A newly discovered fossil ape from northern Egypt has significantly rewritten the understanding of early hominoid evolution. The Masripithecus species, dating back to around 17-18 million years ago, represents the closest known hominoid relation to the lineage that ultimately gave rise to all living apes, including humans.
Ludwig Lausanne's Ping-Chih Ho has been recognized by the American Association for the Advancement of Science (AAAS) for his distinguished contributions to immune metabolism. His research focuses on elucidating the role of metabolism in anti-tumor immunity and advancing cancer therapy.
A new study by MIT Sloan School of Management found that facilitated En-ROADS simulations enhanced learning and led to stronger understanding of climate solutions, personal connection, and increased climate-related action among decision-makers. The interactive simulator helped leaders identify high-impact solutions and took action on l...
Calls to poison centers about kratom increased by over 1,200% between 2015 and 2025, with corresponding rises in hospitalizations and deaths. The drug's growing availability and potency have led to a concerning trend of serious medical outcomes.
A new study from IIT, Uppsala University, and AstraZeneca uses computational chemistry and supercomputers to better understand splicing, a key process in gene expression. The results provide precise insights into splicing dynamics and help explain previously difficult-to-interpret data.
Researchers at NYU Abu Dhabi have discovered new large-scale waves moving deep inside the Sun, driven by magnetic fields far below the surface. These waves provide a unique window into the Sun's interior and help scientists study its magnetic field formation and evolution over time.
The new Altmetric Attention Digest streamlines research impact communication by automatically generating concise, narrative summaries of a research output's attention and influence. This feature provides a deeper understanding of who's engaging with the research, how it's being received, and its real-world impact across diverse channels.
Patients taking GLP-1 weight-loss medications before panniculectomy surgery had higher rates of delayed wound healing but lower rates of seroma. The study suggests a complex interplay between GLP-1 treatment and soft tissue healing after the procedure.
A new cleaning method uses tiny bubbles and sound waves to effectively clean agricultural produce. The study found that vegetables were 90% cleaner when washed with resonating bubbles compared to traditional methods.
A recent study reveals that individuals with an immigrant background tend to assess police violence as less severe, regardless of new evidence. Respondents on the political right continued to exhibit a strong bias, rating police violence lower against those with immigrant backgrounds, even after clear evidence was presented.
A new model combines multiple ways of analysing 3D data, integrating local and global perspectives to interpret complex environments more reliably. The system improves detection of small or partially visible objects in real-world situations, enhancing safety in autonomous systems.
A new study from the University of Exeter found that children and teenagers are more open to vegetarian or vegan diets, but often struggle to keep it up. The study identified key reasons for this, including disgust at learning about animal meat sources, health concerns, and environmental issues.
The program aims to support future pediatric-focused professionals in dentistry, medicine and nursing through competitive scholarships and training. With the gift, UT Health San Antonio will expand access to high-quality care for children and families in Bexar County.
Researchers found that simulated microgravity reduces the number of human sperm able to navigate through channels like the reproductive tract. Progesterone helps overcome this effect.
A new study by the University of Stirling found that beaver-created wetlands had 19% more species than other types of wetland. The research team believes their findings could hint at the scale of past biodiversity loss associated with a lack of beaver-dependent wetlands.
Researchers developed an AI tool called PathogenFinder2 that can detect harmful bacteria before they infect humans. The tool uses protein language models and has been shown to significantly improve the detection of bacterial threats.
Researchers discovered that DNA twisting plays a significant role in CRISPR's mistakes, compromising safety and efficacy. The study used tiny DNA circles called minicircles to capture interactions between CRISPR and DNA, providing insights to help eradicate errors altogether.
Since Scotland's landmark smoke-free legislation in 2006, second-hand smoke exposure has decreased significantly, with a 95.7% reduction in salivary cotinine levels among non-smokers between 1998 and 2024. Despite this progress, many workers still face risk of exposure, particularly in outdoor hospitality settings.
A new UK study suggests that home testing kits could be a game-changer for reducing health inequalities among physically Disabled women. Over 50% of the surveyed women prefer self-testing over traditional clinic visits due to barriers such as discomfort and embarrassment. The proposed scheme will offer DIY test kits to under-screened o...
A KIT study shows that Europe has enough renewable resources to replace fossil fuels in road transport. The research highlights the potential of using diverse raw materials like straw, wood scraps, and organic waste to produce climate-friendly fuels.
Researchers have identified a framework to characterize RNA structure-changing small molecule drugs, which could lead to the development of better treatments targeting RNA directly. The study found that molecules binding to RNA rarely affect its function, while those altering its structure have a bigger impact.
A Universitat Rovira i Virgili study found that male gender, religiosity, and physical aggression are factors associated with higher levels of transphobia. The study collected data from 333 adults and found that men exhibit significantly higher levels of transphobic attitudes than women.
The company has announced an expansion of its innovative diamond open access (OA) model, Collective Pathway to Open Publishing, through agreements with Jisc in the UK and CAUL in Australasia. Six new journals will make their 2026 volumes open access without charging authors an article publishing charge.
A new study reveals the Milky Way's southern halo is up to 12% warmer than the northern half due to an internal combustion engine-like effect caused by the Large Magellanic Cloud. The compression of gas in this process heats up, affecting the temperature difference between the two regions.
Researchers found that older cells' inability to react properly to external stimuli is caused by changes in the packaged form of DNA, called chromatin. This alteration leads to incorrect gene expression and production of unwanted proteins.
Research from Oman tackles food freshness, mental health, and public health to improve everyday life. The issue showcases how local studies contribute to global conversations on sustainability and quality of life.
The IOP Publishing Outstanding Reviewer Awards recognize researchers who deliver exceptional peer review reports, showcasing the essential contribution of reviewers to published research quality. The awards honor over 3,500 reviewers from 74 countries, with notable recognition for lower middle-income country contributors.
Researchers using satellite imagery and remote sensing technology have discovered at least 28 large stone circles in the Golan Heights, surrounding Rujm el-Hiri. These findings suggest a widespread architectural tradition integrated into social and economic systems of the proto-historic Levant.
Researchers found that vitamin D supplementation was associated with increased levels of immunoglobulin A and decreased levels of immunoglobulin G, indicating a more balanced immune response. The study also observed changes in immune signaling pathways and increased activity of regulatory immune cells.
Early-stage drug development worldwide has nearly doubled over the past decade, with China's share increasing from 8% to 32%, according to Georgetown University researchers. The number of early-stage programs increased by 82.4% from 10,417 in 2015 to 18,999 in 2024.
A recent study combines two modelling approaches to capture the seismicity associated with land uplift and earthquake swarms in the Phlegraean Fields. The model explains long-term trends in earthquake activity by combining changes in stress within the Earth's crust with friction behaviour of geological faults.
A large randomized trial shows that continuous wearable monitoring reduces time with dangerously low oxygen levels after surgery, leading to improved composite outcomes and safety. The study found a 30-minute reduction in hypoxemia and a significant risk reduction for desaturation events.
Epigenetic modifiers targeting histone acetylation, methylation, and phosphorylation show significant preclinical promise in CRC. Combination strategies and novel degraders offer pathways to overcome resistance, including PROTACs targeting KDM3A/B that eliminate cancer stem cells via Wnt/β-catenin inhibition.
Researchers developed an AI model that analyzes routine pathology slides to predict breast cancer recurrence and chemotherapy benefit. The model was validated in a large clinical trial and demonstrates fast, accessible, and globally scalable diagnostic capabilities.
A study by researchers at Institute of Science Tokyo has identified a key gene, DOCK10, involved in abnormal insulin secretion in insulinomas. The findings pave the way for novel diagnostic biomarkers and treatment options.
Research reveals increased interannual temperature variability over China, with greater summer variability during the Last Interglacial and stronger winter variability during the Last Glacial Maximum. This study provides a critical long-term perspective for understanding future changes in extreme temperature events.
A recent study published in JAMA Oncology suggests that obesity control is a potentially effective strategy for cancer prevention. The research reveals that successful weight management can lead to a significant reduction in the risk of various cancers, making it an underutilized approach in cancer prevention.
Scientists created a room-temperature, zero-power infrared sensor with high sensitivity and fast response time. The device uses a novel asymmetric electrode structure to separate generated electrical charges, enabling clear images without external power.
Early-stage drug development has nearly doubled globally over the past decade, driven by a shift from a US-dominated system to a two-hub structure. This change may have implications for scientific workforce development, investment, and patient access to new therapies.
Researchers developed a copper complex that selectively induces cuproptosis in cancer cells, killing them without harming healthy tissue. The method is 100 times more effective than existing platinum derivatives and can target treatment-resistant cancer cells.
Researchers used AI to identify key characteristics of catalysts and guide their designs, discovering a universal design principle for copper-based single-atom alloy catalysts. The approach uses machine learning to predict catalyst performance and inspire generalizable design principles.
Elevated uric acid promotes liver damage and disease severity through inflammation, oxidative stress, and metabolic disturbances. Lifestyle interventions, medications, and potential biomarkers are being explored to improve diagnostic efficacy and treatment.
A new study forecasts disruptive Siberian-Arctic heatwaves up to one month in advance by monitoring Arctic stratospheric ozone depletion and Kara Sea ice loss. The model correctly predicted six out of seven major SAH events since 1979.
Dr. Justin Garcia, Kinsey Institute Executive Director, named AAAS Fellow for his distinguished contributions to understanding evolutionary and biocultural foundations of romantic relationships across the lifespan. His work integrates biological, psychological, and social perspectives to examine human intimacy and its impact on public ...
Researchers developed a novel lithium-ion battery anode that stores more than 3500 milliampere-hours per gram, outperforming current graphite-based batteries. The new design, VISiCNT, features a vertically integrated silicon-carbon nanotube structure that maintains performance and stability over hundreds of charge cycles.
NYU faculty Eray Aydil, André Fenton, Anirban Maitra, and Liina Pylkkänen recognized for their groundbreaking work in materials synthesis, neuroscience, cancer research, and language processing. The American Association for the Advancement of Science has selected 449 members as AAAS Fellows this year.
CUNY Graduate Center faculty members Kevin Gardner, David J. Lohman, Vinod Menon, Christina Sormani, and Charles Vörösmarty have been named 2025 AAAS Fellows for their groundbreaking work in various fields. Their research has expanded human knowledge and addressed pressing questions in mathematics, biology, physics, and environmental s...
Researchers found that as systems grow, new functions are added at a slower rate, requiring infrastructure and existing functions to expand. Cities show an exception, where function diversity grows rapidly in smaller cities but slows down in larger ones.
A new set of evidence-based clinical guidelines has been developed to manage recurrent wheezing in infants and toddlers. The guidelines recommend standardized protocols for diagnosing and treating the condition, including laboratory tests and type 2 inflammatory disease testing.
Paul Tesar, a Case Western Reserve University neuroscientist, has been elected as an AAAS Fellow for his distinguished contributions to translational neuroscience. His research has helped elucidate the role of oligodendrocytes in neurological disease and develop regenerative therapies for multiple sclerosis and pediatric leukodystrophies.
Mark Adams, a leading expert in genomics, has been elected an AAAS Fellow for his groundbreaking work in DNA sequencing and genome mapping. His pioneering efforts have laid the foundation for modern precision medicine.
The study developed a novel framework that tracks digital communities over time, analyzing how online groups emerge and disappear. Researchers found that social media interactions can create echo chambers and increase societal polarization.
A joint project between The University of Queensland and the Indian Institute of Technology Delhi has led to the development of an eco-friendly process to convert sugarcane waste into biofuel. PhD candidate Ms Neethu Joshikumar successfully tested a one-pot method using deep eutectic solvent, reducing electricity and time requirements.
Drexel researchers have found that, given the right strain rate, simple liquids can fracture like solid objects. This discovery suggests that viscosity plays a more significant role in the mechanical properties of liquids than previously thought, potentially leading to new possibilities for manipulating liquids in various applications.
Two Baylor University researchers, biologist Dwayne D. Simmons and anthropologist Samuel S. Urlacher, have been elected as AAAS Lifetime Fellows for their distinguished scientific contributions. They were recognized for their research in auditory neuroscience and life history tradeoffs in human physiology.
Researchers developed a holographic data storage approach that combines amplitude, phase, and polarization to store more data in the same space. The new method increases information density while simplifying readout, making it suitable for smaller data centers and faster data processing.
Researchers at Hiroshima University have developed a new experimental method to demonstrate the physical delocalization of individual photons in an interferometer. The study challenges traditional interpretations of quantum mechanics and has significant implications for high-tech sensors and our understanding of reality.
Researchers have identified and overcome metabolic instability as the key barrier to developing ovalicin, a potent relative of fumagillin. Using chem-bio hybrid synthesis, they created metabolically stable drug candidates that worked in animal models of amebiasis.
Professor John Bickle has made significant contributions to the field of philosophy of science and neuroscience, bringing together experts from various disciplines to study the human brain, cognition, and behavior. His work aims to develop new treatments for mental disorders through the isolation of proteins.
Researchers investigated human preferences for robot motion on different household tasks, finding that preferences vary from task to task and should be highly individualized. The study also found that users prefer smoother robot motions than their own movements.
The University of Missouri is honoring three distinguished faculty members as 2025 AAAS Fellows. Paul de Figueiredo is being recognized for his contributions to microbiology, while Roman Ganta advances research on tick-borne diseases. Wesley Warren's expertise in genome-scale data analysis has reshaped research across multiple fields.
Researchers from The University of Osaka propose a compact LED design that directly emits circularly polarized light, potentially simplifying optical devices. The new design uses robust inorganic materials and achieves high levels of both efficiency and polarization degree.
A new deep learning model classifies Japanese Sue ware from 3D scans with high accuracy, using three-dimensional point clouds directly. The model achieved an overall accuracy of 93.2%, performing almost perfectly on visually distinct categories, while focusing on regions that may correspond to expert archaeologists' considerations.
Carole LaBonne and Matthew Goldrick are being honored for their groundbreaking research in developmental biology and language science. LaBonne's work on pluripotent embryonic stem cells has significant implications for understanding birth defects, cancer, and regenerative medicine.
A KAIST research team identified the mechanism by which Graphene Oxide exhibits powerful antibacterial effects against bacteria while remaining harmless to human cells. The technology has been applied to consumer products, including a graphene antibacterial toothbrush that has sold over 10 million units.
UT MD Anderson faculty members Theresa Guise and Stephanie Watowich have been elected as AAAS Fellows, honored for their outstanding contributions to science and society. Their research focuses on endocrinology and immunology, with breakthroughs in cancer treatment and patient care.
The study found that AI-enhanced single-shot cine MRI produces better image quality compared to conventional cine MRI, particularly in participants with arrhythmia. The technique demonstrated a 100% success rate for image acquisition, outperforming conventional cine sequences.
The latest SLAS Technology volume showcases how AI, automation, and portable technologies are transforming drug discovery and diagnostics. This advancement enables the development of innovative therapeutic solutions and improved patient care.
Researchers found that adults who followed routine eating patterns lost more weight than those with varied diets. Those who repeated many of the same foods lost an average of 5.9% of their body weight, compared to 4.3%. Greater calorie consistency was also linked to better results.
Researchers identified MIEL1 as an E3 ligase that cooperates with XBAT31 to regulate thermoresponsive growth in plants. MIEL1 blocks XBAT31's auto-ubiquitination and self-degradation, maintaining its protein stability.
Researchers developed a video modeling program to enhance romantic relationship skills in young adults with intellectual and developmental disabilities. The study found that participants significantly improved their decision-making skills across four relationship domains, averaging 76% accuracy after the intervention. The findings high...
Researchers have identified phage W5 as a safe and effective natural virus capable of eliminating harmful Salmonella on various foods and packaging materials. The study establishes a solid foundation for developing novel phage-based disinfectants or preservatives to combat antibiotic resistance and enhance food safety.
The latest volume of SLAS Discovery highlights advances in 3D cell culture and novel technologies for drug discovery. Small molecule cytokine antagonists and a versatile ELISA for PPI inhibitor screening are among the key findings.
Twelve life science startups have been selected for the Innovation AveNEW program at SLAS Europe 2026. The companies will showcase their products and services in a specially designated area on the exhibition floor, engaging with purchasing influencers and decision-makers from over 40 countries.
This issue highlights advancements in drug discovery, synthetic biology, and laboratory digitalization. SLAS Technology emphasizes scientific and technical advances that enable improved biomedical research and development.
Researchers have developed a new class of carbon materials called 'viciazites' that contain carefully controlled configurations of nitrogen groups, enabling low-temperature operation and efficient CO2 capture. The materials outperform untreated carbon fibers in CO2 uptake and desorption at temperatures below 60°C.
A clinical trial found that high-intensity therapy for patients begun within two weeks of a stroke did not improve hand and arm recovery beyond standard care. Despite having access to extra therapy, neither group did better than a cohort who received standard care alone.
The study developed a novel multi-task deep LASSO algorithm that identified six core clinical indicators, establishing four stable MASLD subtypes with distinct characteristics. The classification system enables targeted interventions, prioritizing fibrosis screening and aggressive cardiorenal protection for specific subgroups.
The American Academy of Sleep Medicine has announced the 2026 award recipients for their exceptional contributions to sleep medicine. The award winners are Dr. Susan Redline, Danny Eckert, Dr. Douglas Kirsch, Dr. Beth Malow, and Dr. Robert Stansbury, recognized for their research, education, advocacy, and clinical care.
East China Normal University's Faculty of Education has been selected for the 2025 Shanghai 'International Communication of Chinese Culture' initiative, highlighting the growing importance of academic platforms in facilitating global knowledge exchange. The journal ECNU Review of Education plays a central role in advancing this initiat...
A study from Stockholm University found a diverse population in medieval Ibiza connected to Europe, North Africa, and sub-Saharan Africa through trade and migration. Genetic analysis also identified the first confirmed case of leprosy in medieval Islamic Iberia.
A new study reveals that over 63% of children waiting for an ADHD assessment with CAMHS spend more than a year on the list, while a third wait over two years. Parents experience significant distress due to lengthy wait times, feeling powerless and uncertain about their child's future.
A University of Michigan study suggests that scientists wearing nitrile and latex gloves while measuring microplastics may overestimate the amount of tiny pollutants in air, water, and samples. The researchers recommend using cleanroom gloves instead to minimize contamination with stearates.
Researchers studying ghost forests along the mid-Atlantic coastline found that changes in stemflow chemistry affect carbon cycling and microbial communities. The team's findings suggest that understanding these processes can help predict which forests are most vulnerable to sea level rise.
Researchers discovered that 240-million-year-old coelacanths used their lung to detect sounds underwater, employing an ossified lung and a canal connecting the hearing organs. This finding provides valuable insight into the evolutionary history of these fish and may also reveal secrets about our own aquatic ancestors.
A new study highlights the importance of fair distribution of carbon dioxide removal rights among countries to halt global warming. The researchers found that unequal allocation can entrench inequality, shifting the climate burden onto future generations.
A study published in Frontiers found that young people with attachment anxiety and difficulties identifying emotions are more susceptible to short video addiction. Mental training, such as mindfulness and attention regulation, can help prevent this addiction by strengthening emotional awareness and cognitive regulation.
Adults who engaged in extended durations of mentally passive sedentary behaviors had a higher risk of dementia. Replacing passive with mentally active sedentary behaviors was shown to reduce the risk of dementia onset in later life.
Researchers developed a machine learning model that analyzes patient demographics, electronic health record data, and blood test results to predict hepatocellular carcinoma (HCC) risk. The model achieved high accuracy and outperformed existing liver cancer risk prediction models, offering potential for widespread use in resource-limite...
A Korean research team has developed a circular low-carbon catalytic process that co-produces gluconic acid and sorbitol from glucose. The process operates under ambient conditions, significantly reducing both energy consumption and carbon emissions.