A decision-support system improved depressive and anxiety symptoms, increased medication adherence, and reduced symptoms over time for patients with major depressive disorder. The system used clinical and demographic predictors to tailor treatment, resulting in better outcomes for patients compared to usual care.
A large-scale study found that human activity is consistently changing the ecosystems of Northern European lakes, altering food webs and affecting salmonid fishes. The research used stable isotopes to examine the impacts of hydropower and human modification on lake environments.
The American College of Surgeons has released a national framework outlining measurable workplace standards for surgeons, aiming to improve surgeon well-being and patient safety. The framework provides customizable standards that can be incorporated into departmental policies and employment contracts.
Semaglutide and tirzepatide prescriptions increased dramatically between 2018 and 2025, while MBS use rates declined substantially starting in 2023. Recent shifts in MBS use may be more pronounced in certain patient subgroups, such as those seeking sleeve gastrectomy or with lower BMIs.
Researchers found that interactions with healthy cells determine a tumor's ability to survive, grow, and progress. The team discovered a 'distress signal' sent by the tumor to nearby fibroblasts creates a supportive micro-environment that shelters the tumor from being cleared.
The AI model can accurately identify disease-causing mutations in human genes and is capable of designing new genomes that are as long as the genomes of simple bacteria. Evo 2 has been trained on over 100,000 species across the entire tree of life and can process genetic sequences of up to 1 million nucleotides at once.
A Mayo Clinic study found that women with abnormal Parkinson's-related protein levels accumulate Alzheimer's-related pathology faster, leading to faster disease progression. The study analyzed data from 415 participants and showed that women's brains progress up to 20 times faster than men's in this regard.
A newly granted patent unveils an innovative energy-dissipation device designed to protect buildings and infrastructure from earthquakes, strong winds, and man-made vibrations. The device is simple, low-cost, and power-independent, making it a viable solution for low-income countries with high seismic risk.
Researchers Judith Holler and Anna K. Kuhlen argue that conversation is not a linear exchange of words, but rather a jointly managed activity in which meaning emerges through coordination. Visual signals like gestures and facial expressions play a crucial role in composing and comprehending meaning.
Researchers at DGIST have developed a technology to precisely control anion defects in eco-friendly quantum dots, enabling record-breaking solar hydrogen production efficiency. The defect-minimized eco-friendly quantum dots exhibited increased charge carrier concentration and prolonged lifetime, allowing for efficient charge migration ...
A study by MedUni Vienna found that up to one-third of patients with advanced alcohol-related cirrhosis can achieve complete regression of liver-related complications through consistent abstinence from alcohol. This 're-compensation' also leads to simultaneous recovery of liver function and a significant reduction in mortality rates.
Researchers found that specific gut bacteria can sense diet and translate information into signals that tell fat cells to burn energy. A low-protein diet activated precise gut microbes that promote beige fat production, leading to improved glucose control and lower cholesterol levels.
Researchers found interactions between soil moisture patterns and wind in the lowest atmosphere influence where storms develop, providing clues to forecasters about location. The study aims to improve certainty about upcoming storms on hot days and save lives, livestock, and property.
Cancer cell-derived small extracellular vesicles can be excreted into urine, according to researchers who tracked their journey in mouse models. The study reveals that glomerular cells actively transport sEVs across the filtration barrier, supporting their use in emerging urine-based cancer diagnostics.
The discovery of Eosteus chongqingensis and Megamastax amblyodus provides a major breakthrough in understanding the evolution of bony fishes, revealing primitive characteristics that evolved much earlier than previously thought. These findings confirm South China as the cradle for the origin of jawed vertebrates.
Researchers analyzed data from over 62,000 participants, finding that loneliness partially mediated the link between anxiety and suicidal thoughts as well as depressive symptoms and suicidal ideation. Targeting loneliness may be a crucial strategy to prevent progression from these conditions.
A new AI-powered tool, Merlin, has been developed to assess 3D abdominal CT scans, identifying anatomical features and predicting disease onset years in advance. The tool surpassed traditional automated tools in tasks such as diagnosing diseases and predicting patient outcomes, with accuracy rates of up to 81%.
A new study by UNC Charlotte scientists has discovered a self-clustering mechanism in the Polycomb protein CBX2 that is essential for initiating gene-repressive condensates and guiding stem cells toward their proper fates. The researchers found that CBX2 clusters recruit two Polycomb repressive complexes, creating multicomponent repres...
A team of researchers uses Quantum Fisher Information to separate individual parameter relevance from cross-parameter correlations in QAOA. This analysis reveals strongly non-uniform parameter relevance that varies with circuit architecture and depth.
A randomized study of 14 young adults found that sparkling water consumption reduced subjective fatigue and improved executive function while playing virtual soccer for three hours. Players who drank sparkling water also committed fewer fouls and had better game enjoyment compared to those drinking plain water.
Researchers used UAV-LiDAR technology to measure deposits on abandoned mountain roads, estimating decadal-scale debris supply. The study found that debris supply increases with steeper slope angles and larger contributing areas, posing a risk for debris flows.
Researchers have developed a new type of solid-state magnesium-air rechargeable battery using nitrogen-doped porous graphene as the cathode. The battery exhibits superior performance and safety compared to traditional systems, with improved chloride resistance and high catalytic activity.
Olivia Asher, a Ph.D. candidate in bioinformatics at UGA, has been selected for the 2026 AIBS & SURA Public Policy Fellowship. She will work with AIBS and SURA policy staff in Washington, DC, to gain hands-on experience with science policy and advocacy efforts.
Scientists have identified five distinct species of antbirds, including two new species, by integrating AI, vocal analysis, and traditional museum work. The study reveals that populations separated by major Amazonian rivers have evolved into distinct species.
This study assesses the educational impact of introducing interest-matched examples in data science education, showing a positive effect on students' motivation and understanding. The findings suggest that instructional approaches grounded in intrinsic motivation theory can improve data science education quality.
A study by the University of Gothenburg found that young adults are more likely to consume healthcare through online apps, especially when no patient fees are charged. Women tend to have higher consultation rates than men, who experience a sharper decline in consultations once they turn 20.
A study by MIT researchers found that nitrous oxide can hamper the growth of certain soil bacteria dependent on vitamin B12 for methionine biosynthesis. The findings suggest that N2O production in agricultural settings could influence microbial communities, potentially impacting crop health.
Recent studies identify distinct gut microbial communities in people with dyslipidemia, suggesting a connection between the gut microbiome and heart disease precursor. The researchers found higher levels of Bacteroides caccae and lower levels of bacteria linked to metabolic stability. Future research aims to restore functional balance ...
Florida Atlantic University has received a $4.5 million grant from the US Air Force to establish a high-fidelity platform for autonomous decision-making and real-time sensor fusion research. The T-1A Jayhawk simulator will be used to study cognitive performance, situational awareness, stress and decision-making under pressure.
The researchers created a 3D-printed model of the left side of the heart that contracts and beats, allowing for rehearsing of important heart surgeries on a model that acts like the real thing. The model was successfully used to repair a defective mitral valve and demonstrate reduced regurgitation.
A new study from Hiroshima University revealed that pre-employment career resilience, particularly optimism about the future, plays a crucial role in forming vocational identity and coping with reality shock. The study suggests university-level programs to promote career resilience before students enter the workplace.
The SimTac simulator accurately models biomorphic sensors using particle-based deformation, light-field rendering, and neural network prediction. It achieves high performance in optical and mechanical response accuracy, adaptability to diverse morphologies, and simulation efficiency.
Researchers found that black soldier fly larvae can break down RNA viruses in organic waste, reducing potential risks. The larvae's frass still contained some active viruses, highlighting the need for additional treatment.
Research supports a nuanced view of IMF reforms, finding them welcome in autocracies but contentious in democracies. The study suggests IMF programs can align national economic policy with domestic preferences, with implications for global economic governance.
New studies reveal that medication nonadherence in people with chronic obstructive pulmonary disease (COPD) is often caused by affordability and limited understanding of medications. This can lead to quicker lung function decline, more frequent exacerbations, and a higher symptom burden.
Research reveals that salivary bacteria from gum disease alter gut metabolism, driving osteoclast activity and systemic bone loss. Microbial metabolites like indole-3-lactic acid inhibit osteoclast differentiation and activity.
A recent study has shed light on the processes that drive mitochondrial uptake and its benefits for cells. Isolated mitochondria were found to be taken up by mesenchymal stromal cells, enhancing proliferation and cytoprotection, and improving energy metabolism.
A new study challenges the common method used worldwide to measure genetic progress in crop breeding, finding that most reported gains are due to maintenance breeding, not genetic improvements. This has significant implications for agricultural research policy and investment, highlighting the need for more robust evaluation methods.
A new report sets out ten priority areas for improving climate education in UK schools, calling for coordinated support across the whole education system. The experts argue that while the curriculum review is a welcome step, real change requires attention to issues such as teacher training and sustainability actions.
A global team led by UC San Diego's Ludmil Alexandrov is receiving a $25 million Cancer Grand Challenges award to decipher the molecular origins of cancer. The team aims to identify unique patterns of DNA damage and their sources, which could lead to new prevention and treatment strategies.
Researchers have demonstrated that stem cell treatment can be effective even when initiated after motor deficits appear in cerebral palsy. The study used stem cells from human primary tooth pulp to treat chronic-phase cerebral palsy in rat experiments, showing improved motor and learning functions in the treated group.
A new study has demonstrated the safety of short-term vaginal estrogen therapy in younger survivors of endometrial cancer. The research shows that local, low-dose vaginal estrogen does not increase a woman's risk of cancer recurrence, providing hope for women who have experienced this type of cancer.
Researchers from the University of Waterloo have identified the key factor behind estrogen's protective effects against high blood pressure, finding vasodilation to be the crucial mechanism. This discovery holds promise for more effective treatment options for women after menopause, when estrogen levels naturally decline.
Researchers investigated which characteristics of crystals made them fascinating to early humans, using experiments with chimpanzees. The chimps showed a strong attraction to transparent and crystalline properties, suggesting that this attraction may have deep evolutionary roots.
Sleep deprivation can weaken eyewitness recall, reduce autobiographical detail, and increase susceptibility to misinformation in legal proceedings. This can lead to false confessions and wrongful convictions, as exhausted individuals may prioritize short-term relief over long-term consequences.
Researchers at University of Illinois have developed a new method using solar energy to power a key chemical reaction in the textile, plastic, chemical, and pharmaceutical industries. This method can significantly reduce the industry's carbon footprint by eliminating harsh oxidizing byproducts and minimizing carbon emissions.
The Centre for Computational Social Science and Humanities (CSSH) at NUS combines computational methods with social science and humanities to better understand complex social phenomena and develop solutions. CSSH aims to generate research that improves lives, strengthens institutions, and shapes more inclusive societies.
A new process-based model, SAL-GPP, has been developed to accurately assess the carbon sequestration capacity of global salt marshes. The model reveals that global salt marshes have an average annual gross primary production of 66.89 Tg C yr⁻¹, with hotspots in regions like China's southeastern coast and Western Europe.
A new strategy for estimating storm water in sewers uses a combination of methods, including long-term average flow rate and biological oxygen demand. This approach can improve accuracy by over 10% and provide more plausible estimates for benchmarking potential improvements to sewer systems.
Researchers propose an integrative framework to explain sepsis-induced granulopoiesis shift. Immature neutrophils exacerbate tissue damage and contribute to immune paralysis. Precision interventions targeting metabolic pathways and biomarker-guided stratification are suggested.
Researchers discover that butyric acid, a gut microbiota-derived metabolite, enhances the activity of natural killer cells expressing CX3CR1, restoring immune cell migration and cytokine production. This gut-lung immune axis may be harnessed to improve outcomes in severe bacterial infections.
The study found that carbonation occurred during shallow crustal extension, challenging earlier interpretations of deep subduction environments. Naturally carbonated ultramafic rocks provide a valuable natural analogue for long-term carbon storage in solid minerals.
Researchers found that concrete slab size is the worst offender in terms of carbon emissions, with changing this feature alone able to save large amounts of emissions. Optimize design decisions such as floor thickness, building materials, and construction culture to reduce pollution.
Potassium KCNQ2/3 channels need full functionality to work properly in the brain and reach their correct location. This is linked to their regulation by protein ankG. Altering channel functionality affects neuronal excitability and may contribute to developing new therapeutic strategies for epilepsy.
A randomized clinical study found that adding a fungal probiotic to standard enteral nutrition reduced nosocomial infections in critically ill patients with severe pancreatitis. The intervention also stabilized intestinal and respiratory microbiota, highlighting the potential of microbiome-targeted therapies. Fungal probiotics may offe...
A study found that individuals trying to diet are more likely to choose unhealthy snacks when feeling negative emotions, but emotional awareness is the key to maintaining healthier eating habits. Practicable strategies like mindfulness exercises and checking in with feelings can help dieters stay on track.
Scientists have engineered a microbial assembly line that converts plastic waste into a variety of useful products, including biopolymers, enzymes, and electricity. The breakthrough uses pyruvate as a universal currency to generate a wide range of outputs.
A University of Sydney-led study found that honey made from mixed floral sources has superior performance against bacteria, with high levels of bioactive compounds. The findings could help develop new treatments for drug-resistant infections while supporting bushfire recovery and sustainable beekeeping practices.
Researchers developed a novel doping strategy using Sb and Ni to optimize GeTe's electronic band structure and thermal conductivity. This approach yielded exceptional thermoelectric performance by enhancing power factor and suppressing thermal conductivity, achieving a peak ZT of 2.15 at 773 K.
Researchers have developed high-temperature-resistant sinoite fibers with a near-stoichiometric Si2N2O ratio, exhibiting outstanding high-temperature resistance and mosaic-shell formation at 1700°C. The novel fibers maintain tensile strength and low-dielectric properties, making them promising for thermal protection systems.