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Unlocking the cell's 'gatekeeper': UC Irvine researchers discover critical RNA quality-control factor, LENG8

03.26.26 | University of California - Irvine

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Molecular Cell

10.1016/j.molcel.2026.02.023

Cells

LENG8 mediates RNA nuclear retention and degradation in eukaryotes

19-Mar-2026

This work was supported by the National Institutes of Health under awards R35GM149294, R01CA297834, DP2GM149554; a Hewitt Foundation Postdoctoral Fellowship; and the Washington Research Foundation Postdoctoral Fellowship. Additional support was provided by UCI core facilities funded by P30CA062203, CA-62203, and NIH-S10OD032327-01.

Additional Media

Keywords

Rna

Article Information

Journal
Molecular Cell
DOI
10.1016/j.molcel.2026.02.023
Subject of Research
Cells
Article Publication Date
2026-03-19
Article Title
LENG8 mediates RNA nuclear retention and degradation in eukaryotes
COI Statement
This work was supported by the National Institutes of Health under awards R35GM149294, R01CA297834, DP2GM149554; a Hewitt Foundation Postdoctoral Fellowship; and the Washington Research Foundation Postdoctoral Fellowship. Additional support was provided by UCI core facilities funded by P30CA062203, CA-62203, and NIH-S10OD032327-01.

Contact Information

Matt Miller
University of California - Irvine
matt.miller@uci.edu

Source

Original Source
https://medschool.uci.edu/news/unlocking-cells-gatekeeper-uc-irvine-researchers-discover-critical-rna-quality-control-factor

How to Cite This Article

APA:
University of California - Irvine. (2026, March 26). Unlocking the cell's 'gatekeeper': UC Irvine researchers discover critical RNA quality-control factor, LENG8. Brightsurf News. https://www.brightsurf.com/news/12DRMKO1/unlocking-the-cells-gatekeeper-uc-irvine-researchers-discover-critical-rna-quality-control-factor-leng8.html
MLA:
"Unlocking the cell's 'gatekeeper': UC Irvine researchers discover critical RNA quality-control factor, LENG8." Brightsurf News, Mar. 26 2026, https://www.brightsurf.com/news/12DRMKO1/unlocking-the-cells-gatekeeper-uc-irvine-researchers-discover-critical-rna-quality-control-factor-leng8.html.