AnalySwift, a Purdue University-affiliated company, has received a Phase II STTR award to develop a robotic welding technology that enables disassembly and reassembly of large truss structures in space. The technology will simulate advanced materials and structures needed for this activity, including the feasibility of repurposing full...
Researchers at Purdue University have developed L-32, a quinolone-based inhibitor that targets PTPN22, a negative regulator of the immune system. This compound promotes robust antitumor immunity and has improved potency, selectivity, and cellular efficacy compared to previous derivatives.
New Purdue research improves air quality forecasting by understanding how organic aerosol molecules interact and affect evaporation rates. The team discovered that neighboring molecules in aerosol mixtures tend to
Researchers developed a wearable solution to optimize prosthetic fit and comfort, using embroidered textiles with sensing capabilities. The system detects normal and shear forces at the limb-socket interface in real-time, providing close-loop feedback for pressure levels.
PaveX will develop an AI-sensor-based system to collect street-level data and produce practical road condition ratings, helping agencies plan repairs sooner and more efficiently. The project aims to improve distress detection reliability and reduce route planning overhead.
Asteroid impact created a massive dust cloud that trapped heat, causing widespread wildfires and spontaneous combustion. The cloud led to population collapse and atmospheric contamination, ultimately killing most dinosaurs and other species.
OYE Therapeutics announced positive Phase 1 results for OYE-101, a proprietary intravenous caffeine formulation. The study demonstrated the safety and tolerability of OYE-101 in healthy adult volunteers, supporting its planned development as a treatment to support emergence from general anesthesia and deep sedation.
Researchers at Purdue University have developed a way to achieve simultaneous high strength and plasticity in cobalt aluminum (CoAl) intermetallics. This is achieved through the introduction of dislocations and amorphous interfaces, which enable the materials to withstand extreme forces without fracturing.
Researchers at Purdue University have developed a next-generation technology platform designed to dramatically accelerate one of the slowest stages of cancer drug discovery. The platform combines chemical synthesis, biological testing, and mass spectrometry into a single integrated workflow, allowing researchers to generate, evaluate, ...
The PanAMP study assesses the impact of PanCystPro on clinicians' decision-making for patients with pancreatic cysts. The study aims to provide insights into surveillance and treatment strategies for those at higher risk for pancreatic cancer.
Novin AgriTech received an $174,906 USD grant from the US Department of Agriculture to develop nitrogen use efficiency trait in elite wheat cultivars. The company's platform technology will introduce genetic tools to improve nitrogen use efficiency.
The FDA has merged two of OYE Therapeutics' Investigational New Drug applications, creating a more streamlined regulatory framework for development across related programs. This move is expected to improve regulatory efficiency, reduce duplicative development activity, and simplify operational execution.
Four teams of Purdue University student entrepreneurs won a combined $50,000 from the Purdue Innovates Incubator for their innovative solutions in healthcare and education. The winning teams included echoSURE Inc., VitaWave Tech Inc., CalcGPT, and Kova Group Inc.
OYE-101, a novel intravenous caffeine formulation, has been developed to accelerate recovery from general anesthesia and deep sedation. The company's lead program is being evaluated in a scientific bridging study to support a 505(b)(2) NDA for OYE-101.
A software system, developed by Purdue University researchers, enables users to create a customized digital binder that can be searched and shared resource referrals. The system improves care coordination among health centers and social service organizations.
Researchers discovered a new type of protein modification related to cellular mutation that impairs an enzyme's ability to help drive energy processes. The discovery opens a new route to therapeutic cancer intervention, particularly for IDH mutations common in multiple cancer cells.
Researchers have discovered an RNA-guided CRISPR system that can activate genes without cutting DNA, opening up new possibilities for gene regulation and therapeutic strategies. The system uses a strand of RNA as a guide to recruit the cell's transcription machinery, allowing for precise control over gene expression.
Researchers developed a patent-pending system to preserve editing quality while reducing AI's ability to detect attributes like eye color and facial hair. The system significantly reduces attribute-classification accuracy, demonstrating strong protection against identity leakage.
Wavelogix, a concrete sensor manufacturer, has received a $500,000 grant from the National Science Foundation to refine and scale its Rebel concrete strength sensing system. The system enables faster, data-driven decisions through real-time concrete strength monitoring.
Engineers at Purdue University have developed a patent-pending method to estimate the location, orientation, and radius of underground utility pipes using ground-penetrating radar. This innovation could help prevent hazardous strikes during construction projects, reducing financial losses and service disruptions.
A Purdue University-developed contraceptive vaccine reduces fertility in feral horses, deer, swine, and other animals, overcoming limitations of existing models. The vaccine, based on a male sperm protein, induces a long-lasting immune response and infertility in female mammals, with promising results for wildlife management.
The company's CAP-accredited laboratory performs the PanCystPro assay, which utilizes proprietary BioMatra optical reporter platform to help clinicians accurately rule out malignancy in pancreatic cystic lesions. Amplified Sciences' lab has also validated its unique protease turnover assays through CAP accreditation.
Approximately 40 cancer patients will receive LMP744 for five consecutive days, with biological analyses conducted on brain tissues before and after treatment. If results are favorable, treatment will continue for 12 cycles to evaluate parameters such as progression-free survival and overall survival.
OYE-101, a novel intravenous caffeine formulation, aims to accelerate recovery from general anesthesia and deep sedation in adults. The FDA-cleared treatment also seeks to address opioid-induced respiratory depression and related overdose situations.
A Purdue University team led by Kyle Cottrell has discovered a new therapeutic target for triple-negative breast cancer, a deadly form of breast cancer lacking targeted therapies. The researchers identified dsRNA-binding proteins, specifically PACT, which suppress another protein called RNA-activated protein kinase (PKR).
A Purdue-developed mRNA therapy delivery system has shown promise in targeting bladder cancer cells with improved efficiency. The system, called LENN, can be freeze-dried and stored for several days without losing its biological activity.
Intellicule will utilize state-of-the-art deep-learning techniques to expand structural modeling and analysis for cryo-EM data. The company aims to overcome current limitations in biomolecular modeling, enabling the detection of atoms in low-resolution images.
The company has secured $5 million in funding to support Phase 1 and pivotal trials for its therapies aimed at addressing opioid-induced respiratory depression and improving anesthesia recovery. This financing marks a transformative moment for OYE Therapeutics, positioning the company to enter clinical development with confidence.
Researchers at Purdue University are testing a computer-vision method to analyze smartphone photos of pregnant women's eyes to predict preeclampsia risk. The two-year study aims to reduce maternal mortality in Africa and could potentially save thousands of lives.
A subset of epidermal cells in plant leaves serve as 'first responders' to chemical cues from bacterial pathogens, warning neighboring cells about the presence of an attacker. This local wave of calcium ions differs from those generated by wound-induced cellular damage, indicating distinct mechanisms for specific types of pathogen attack.
The discovery of aluminum-rich kaolinite clay suggests that areas of Mars may have once supported humid climates and heavy rainfall comparable to tropical environments on Earth. The finding provides significant insight into the planet's past environmental stages and how it came to its current barren state.
Researchers at Purdue University have achieved a long-sought milestone by controlling light with light itself at the most fundamental level using single photons. The discovery could enable photonic computing and revolutionize data centers, optical communications, and data transfer systems.
Researchers at Purdue University have developed an optical technique to observe individual particles in a battery charging, enabling the analysis of heterogeneity in composite electrodes. This breakthrough allows for the creation of better batteries by understanding the distribution of charge within the electrode.
A new analytical tool using Raman spectroscopy enables rapid monitoring of vaccine quality and quantity, with results in 30 seconds or less. The tool operates on the production line, saving time and money in vaccine production.
Research shows strong Midwest summer storms can puncture the stratosphere, bringing aerosols and burning biomass from western wildfires. This could affect the ozone layer's stability and warm the stratosphere.
CompositesAI helps users create and analyze composite products without requiring in-depth technical knowledge. The platform is initially focused on rotor blades for air mobility, helicopters, and wind turbines, but its uses will expand to handle other composite structures.
The startup has assessed over 3,400 miles of Indiana roads using advanced computer vision algorithms to quickly and objectively assess pavement conditions. This platform provides actionable insights without requiring in-house data analysis expertise or costly hardware.
Researchers at Purdue University have developed fidget-controlled robots that utilize metastability to create soft robotic systems. These robots use bistable domes to perform tasks such as grasping and classifying objects, demonstrating the potential for physical systems to replace electronic components in challenging environments.
A new study by Purdue University researchers reveals that hurricanes grow in size faster when traveling over locally warm waters, which can help improve daily forecasting of hurricane size and impacts. This discovery has the potential to better model hurricane size in long-term risk models used by industry.
A new study by Purdue University engineers warns that a nationwide switch to electric homes and vehicles could overwhelm the power supply, leading to increased risk of outages. However, key measures such as home insulation, equipment efficiency, and coordinated device operation can reduce costs by up to 40%.
Researchers at Purdue University have developed an algorithm that recovers detailed spectral information from photographs taken by conventional cameras. The method uses computer vision, color science, and optical spectroscopy to achieve high spectral resolution comparable to scientific spectrometers.
Researchers have made key advances in synthesizing high-entropy MXenes, a family of 2D nanomaterials with tailored properties. By understanding the role of entropy and enthalpy, they created nearly 40 new layered materials with varying numbers of metal combinations.
Researchers at Purdue University develop atomic-scale spectroscopy using ultrathin 2D materials, enabling improved resolution for NMR spectroscopy. The breakthrough has potential applications in quantum computing and quantum communications.
Quantum Research Sciences is partnering with Purdue's Rosen Center for Advanced Computing to develop an AI-driven platform called ACID-R. The platform uses AI to quickly deliver details on commercial products and services, streamlining the process for the Air Force to identify needed technologies from the private sector.
A team of researchers has developed a new method to produce sturdy and reusable bioplastics from domestic raw materials, reducing reliance on petroleum-based chemicals. The bioplastics, known as polyhydroxyalkanoates (PHAs), have similar levels of toughness and malleability to traditional plastics, but are infinitely recyclable.
A study of Bennu samples reveals the asteroid reflects light differently at red and blue wavelengths, offering insights into solar system evolution. The findings also enable future research on asteroid navigation and selection.
Researchers at Purdue University have developed a new method to study biochemical processes that impair the immune system's ability to recognize and kill cancer cells. The method involves tracking RNA-binding proteins and extracellular vesicles, which can compromise immunotherapy.
New research from Purdue University reveals how moisture influences atmospheric blocking, a phenomenon that often drives heat waves, droughts, cold outbreaks and floods. The study introduces a new mechanism showing that moisture-induced diabatic heating strengthens ridge blocks but weakens dipole blocks.
Purdue researchers found that heat-based hair care routines release significant amounts of airborne nanoparticles, posing serious health risks. The team's study reveals that using typical store-bought hair care products can expose individuals to upward of 10 billion nanoparticles in a single session.
GeniPhys has received FDA clearance for its self-assembling collagen scaffold, Collymer Self-Assembling Scaffold (SAS), which supports cellular infiltration and vascularization. The technology is indicated for various wound types and anchors a growing intellectual property portfolio with nearly 20 issued or pending patents.