Researchers found that eEF1A2 is significantly overexpressed in gallbladder cancer and correlates with advanced lymph node metastasis and poor patient survival. Targeting the EEF1AKMT4-eEF1A2 signaling axis may suppress translation-driven tumor growth and halt lymphatic spread.
Researchers at MIT discovered that gene circuits can reshape DNA folding and affect gene expression in human cells. The study found that rearranging genes along a DNA strand, or 'gene syntax,' can amplify or suppress the expression of neighboring genes.
The study reveals that decision-making occurs through nested feedback loops, not sequential stages, and can be emulated to create more intelligent AI. This finding has the potential to improve AI's power efficiency and effectiveness.
Researchers identify strong Brønsted acid site (BAS) in fluorinated γ-Al₂O₃ using advanced solid-state NMR techniques. The site is present only on fluorinated alumina and exhibits exceptional robustness, enhancing catalytic activity and aromatization performance.
A physics-guided neural network called SGARNet is developed to address challenges in lensless multi-core fiber imaging. It reveals the frequency-domain characteristic of honeycomb artifacts and introduces a SpectralGate module to selectively suppress artifact-related components, preserving useful image details.
Researchers from Nagoya University developed a two-step synthetic method for dihydrodinapthopentalenes, conductive organic molecules with complex synthesis. The new mechanochemical method synthesizes DHDPs in 15 minutes with minimal solvent waste and structural constraints.
A research team has uncovered the atomic-scale understanding of how water drives structural reconstruction in oxide catalysts. The study reveals distinct hydroxylation pathways for different CoOx nanostructure initial structures in the presence of water.
A bimetallic NiFe catalyst was designed to overcome the activity-selectivity trade-off in furfural hydrogenation. The introduction of Fe creates synergistic active sites, boosting selectivity toward furfuryl alcohol from 38% to >90% at nearly full conversion.
Researchers examined two mechanisms of whole genome duplication in cells, finding that cytokinesis failure leads to more stable and viable cells, while mitotic slippage results in uneven chromosome distribution and reduced viability. The study suggests targeting chromosome separation could help limit survival of abnormal cells.
Researchers at UC Santa Cruz's Forest Fear Lab discovered that the dense upper story of the Amazon carries the cries of frightened birds to other animals, forming a shared information network. Small bird species are key drivers of this acoustic 'information highway,' with larger species also joining in.
A new rulebooks framework developed by Iowa State University researchers provides a principled way for autonomous systems to rank and reconcile competing goals. The framework avoids the issues of blending weighted trade-offs, allowing systems to clearly define which rules come first and choose the least harmful option.
A study at Saitama University found that subtle changes in molecular structure can significantly affect aggregation and interfacial behavior of sugar-based surfactants. The researchers demonstrated that the sulfur oxidation state alters the relationship between aggregation in water and surface tension.
A new review found that GLP-1 weight-loss drugs significantly reduced the risk of heart attacks, strokes, and premature death. The treatment also lowered rates of non-fatal heart attacks, hospital admissions for heart failure, and deaths from any cause.
A small trial found that once-weekly semaglutide injections reduced heavy drinking days by an average of 12 days in patients with alcohol use disorder and obesity. The study showed a 50% higher reduction than the placebo group, suggesting potential benefits for GLP-1s in treating alcohol use disorder.
The American Heart Association warns that healthcare affordability has reached crisis levels, with total spending approaching $5 trillion annually. The association proposes five guiding principles for action by lawmakers and policymakers to address the issue.
A growing gap in cervical cancer incidence rates between high- and low-income countries threatens to escalate unless prevention efforts are increased. Researchers urge universal vaccination for girls and boys, as well as catch-up campaigns, to close the gap and prevent nearly 37 million cases of cancer by the end of the century.
A study by Boston Children's Hospital researchers found that the US missed four out of seven measles elimination status indicators, with most at risk. The latest outbreak has spread continuously for over a year and affected 45 states since January 2025.
A new study published in the Journal of the American Heart Association found that methamphetamine use accounted for nearly 15% of heart attacks in a northern California study. People who suffered meth-related heart attacks were often young- to middle-aged men without traditional heart disease risk factors, highlighting the need for spe...
A recent study found an association between early-onset colorectal cancer and exposure to certain pesticides, particularly picloram. However, experts warn that further investigations are needed to confirm causality and establish a biological mechanism.
A new pretargeted radioimmunotherapy technique has been shown to be effective and safe in eradicating tumors from a preclinical colorectal cancer model. The multi-step theranostic approach delivers alpha-emitting radiation directly to tumors while limiting exposure to healthy tissues.
A new study reveals that impaired protein recycling is the key factor in T cell exhaustion, allowing researchers to develop a 'tag and sort' fix to restore normal proteostasis. This approach boosts the potency of cell therapy against cancer.
Researchers present findings on sociodemographic disparities in hypertensive disorders of pregnancy, highlighting the need for better characterization and management of these conditions. Dr. Basma S. Faris discusses reframing PCOS as a chronic disease requiring longitudinal care.
Research led by University of Utah biologists shows that host genetics and sex influence how influenza viruses evolve. Female mice from a specific strain exhibit accelerated virulence gains compared to male mice.
A new study by Lee Gettler of the University of Notre Dame found that COVID-19 lockdowns had a limited lasting effect on fathers' involvement in childcare, contrary to initial reports. The 15-year longitudinal data showed no significant change in fathering behaviors before and after the pandemic, with most dads resuming their pre-pande...
The RURAL Cohort Study aims to understand why residents of rural communities experience higher rates of heart, lung, and blood-related diseases, as well as shorter life expectancy and less-than-optimal overall health outcomes. The study uses a custom-built mobile examination unit to bring research directly to the community doorstep.
Researchers found significant loss of neurons in the locus coeruleus, a second critical region involved in arousal and muscle tone regulation. This finding suggests an immune-mediated process and challenges the prevailing explanation for narcolepsy with cataplexy.
A new liquid biopsy method has been developed to predict the response to immunotherapy in high-risk breast cancers. The study found that repeated blood sampling can assess and predict the evolving antitumor immune response to therapy, offering a potential tool for guiding immunotherapy decision-making.
The São Paulo School of Advanced Science in FoodOmics aims to advance understanding of omics technologies in food and nutrition. The event will feature keynote lectures, workshops, and interactive sessions with renowned researchers from around the world.
Researchers at Rice University have developed a method to make perovskite-based photovoltaics more durable by adding two key ingredients, skipping the yellow phase and degrading slower. The films retain 98% of their initial efficiency even after 1,200 hours of exposure.
The review highlights how retrieval-augmented generation can improve the accuracy, transparency, and clinical reliability of AI tools in cancer care. RAG-enhanced systems produced more accurate results than standard AI models across multiple studies.
A new study published in Science Advances identifies IRS4 as a promising drug target for multiple solid tumors, offering hope for safer cancer treatments. By using AI and natural mutations, researchers prioritized targets with high therapeutic indexes to minimize toxicity.
A new randomized clinical trial shows that a low-fat vegan diet reduces greenhouse gas emissions by nearly three times more than a Mediterranean diet. The study also found significant improvements in key cardiometabolic outcomes, with the majority of environmental gains driven by eliminating meat, dairy, and eggs.
A new report highlights the catastrophic risks of nature loss on food systems, economies and societies. Chronic pressures like soil degradation and water scarcity are already reducing crop yields and increasing food prices.
Researchers at UBC Okanagan have made a groundbreaking discovery in wireless communication by developing nonlinear intelligent surfaces that can process electromagnetic waves more efficiently. These surfaces mimic neurons in computerized neural networks, enabling complex signal transformations and improved communication reliability.
A new study published in Current Developments in Nutrition shows that adopting a low-fat vegan diet can rapidly reduce environmental impact while improving metabolic health. The 12-week randomized clinical trial found dramatic reductions in greenhouse gas emissions and cumulative energy demand.
The new 21-bed ICU will increase access to advanced care and enable more Queens residents to receive care locally. Construction is expected to take approximately 16 months and will be funded in part by New York City and State as well as through Mount Sinai’s capital resources.
A new study by iC3 researchers found that Neogloboquadrina pachyderma shells can grow with different chemical compositions, affecting temperature estimates. This discovery could help improve reconstructions of past polar ocean conditions and provide more accurate climate records.
Researchers suggest treatment could start during pregnancy to prevent brain damage and reduce neurological harm. A new RNA-based therapy reduces abnormal electrical currents in patient-derived excitatory neurons.
A new study by Carnegie Mellon University researchers found that real-time feedback on collaboration metrics does not improve team performance and can even make it worse. By narrowing the feedback to a single metric, teams focused too much on that signal and neglected coordination strategy, leading to decreased overall performance.
This journal issue examines the evolution of traditional Chinese medicine through texts, practice, empire, and global cross-cultural exchange. Key findings include the gradual development of foundational concepts like the three yin-yang system and the concept of Du, as well as the role of medicine in political and social systems.
Researchers have developed a coherent Raman spectroscopy method that directly detects ångström-scale molecular films at interfaces without plasmonic enhancement or electronic resonance. This approach suppresses strong substrate background signals, allowing for highly sensitive interfacial Raman spectroscopy.
A new study reveals a sharp rise in water bead ingestions among young children, with a 6,532% increase from 2019 to 2023. The majority of ingestions occurred in residences and among children under 3 years old, highlighting the need for primary prevention and education.
A KIT spin-off has developed a photoreactor panel that generates hydrogen directly from sunlight and water, avoiding expensive electrolyzers. The technology offers a simpler, more scalable approach to green hydrogen production, making it suitable for local on-site use or large-scale solar projects.
A new analysis confirms that a small number of plant species drive changes in community temperature profiles under warming temperatures. The study found that these dominant species remain influential even as warming increases, making it easier to manage for climate change by focusing on key contributors.
Researchers studying RNA pollution's impact on aging brains seek to develop therapeutic strategies for neurodegenerative diseases like Alzheimer's. Sanford Burnham Prebys scientist Anne Bang will use advanced robotics to test thousands of compounds.
Research suggests that high-intensity exercise is most effective in reducing sleep disturbances among older adults with mild cognitive impairment. Light activity also shows some benefits, while moderate exercise has little impact. Tailored exercise programs could help prolong quality of life for this growing demographic.
The new framework, published in PNAS Nexus, offers guidance for building human-AI teams that are effective, accountable, and aligned with human values. It focuses on reasoning, memory, and attention as core processes that can be distributed across people and AI systems.
A new study from the University of Mississippi found that younger teens are most likely to try psychoactive inhalants like nitrous oxide. The study also linked inhalant use to certain behaviors such as smoking tobacco and getting into fights, with teenage girls having the highest odds of developing inhalant use disorder.
Researchers at Weizmann Institute and Washington University School of Medicine developed a CAR-T therapy that significantly reduced amyloid deposits and inflammation in a mouse model of Alzheimer's disease. The therapy holds promise for treating neurodegenerative disorders, including ALS and Parkinson's disease.
Researchers found that blocking energy production pathways can slow tumor growth in group 3 medulloblastoma, an often-fatal form of pediatric brain cancer. An experimental therapy targeting energy metabolism has shown promise in reducing tumor growth in mice.
The partnership aims to bring academia and practice closer together, creating new momentum for research, teaching, and society. Researchers from Goethe University's Faculty of Sports Sciences are now based at Eintracht Frankfurt's Sportquartier im Stadtwald.
New research from West Virginia University finds that judges are adopting generative artificial intelligence in courtrooms, but remain committed to human control over judicial decision-making. Judges use AI for administrative tasks like document summarization and case organization, but prioritize legal reasoning and final judgment.
A new review highlights the emotional, physical, and financial challenges faced by caregivers of women living with ovarian cancer. Caregivers experience anxiety, depression, grief, and burnout, alongside practical barriers such as financial hardship and limited communication with healthcare providers.
A large language model exceeded physician baselines in clinical reasoning tasks, including emergency room decisions and identifying likely diagnoses. The study highlights the need for rigorous prospective trials to evaluate the impact of AI on clinical practice.
Researchers discovered a small molecule, UNI418, that destabilizes key DNA repair proteins, making drug-resistant cancer cells vulnerable to PARP inhibitor therapy. This approach restores tumor sensitivity and improves treatment outcomes.
Researchers have identified a newly discovered organelle, the hydrogenobody, which powers methane machine in livestock. The organelle produces hydrogen while regulating oxygen levels, supporting methanogenic archaea and amplifying methane emissions.
Researchers discovered that activated T cells secrete vesicles carrying DNA that enters immune and tumor cells to enhance the immune response against tumors. Preclinical experiments showed that this approach can boost T cell attacks against tumors and improve treatment outcomes.
Scientists at Heriot-Watt University have developed a new way to control the polarization of light, opening up new possibilities for medical tools and quantum technologies. The breakthrough achieves full control over light oscillation in real-time using only light, with no electronics or moving parts.
The FDA has merged two of OYE Therapeutics' Investigational New Drug applications, creating a more streamlined regulatory framework for development across related programs. This move is expected to improve regulatory efficiency, reduce duplicative development activity, and simplify operational execution.
Scientists discovered that evolution used the same genes, ivory and optix, to evolve near-identical colour patterns among distantly related butterfly and moth species. This finding suggests that life on earth may be more predictable than first imagined, with nature following a particular route.
Researchers aim to develop novel quantum algorithms for molecular simulation, targeting computational bottlenecks in drug discovery. The collaboration combines expertise in quantum chemistry and sampling techniques with quantum computing capabilities.
Flinders University experts caution that AI's impressive capabilities do not automatically translate into safe use for patients. The researchers stress the need for strong governance and clearer standards for evaluation to ensure AI supports doctors in busy care settings.
A new study estimates that urban agriculture in European cities could produce up to 20 million tons of vegetables annually, representing roughly one-third of the region's current vegetable production. This could supply around 28% of Europe's vegetable demand for 190 million Europeans.
A mass mating event among yeast strains revealed specific preferences for partner selection. The study showed that yeast tend to choose partners that produce fitter offspring, with successful pairs exhibiting reduced genetic distance. This suggests an ancient and fundamental mechanism for mate choice in sexual reproduction.
The study reveals that the first four layers of water molecules possess a well-defined orientational structure with alternating molecular tilt and twist angles. This new understanding has important implications for processes at aqueous interfaces, including electrochemical devices such as batteries.
A study published in Frontiers in Ecology and Evolution found that optimal birth weight for minimal kidney damage during extreme endurance events is around eight pounds. Individuals with lower or higher birth weights may face a greater risk of kidney stress or damage.
A study reveals that caesarean delivery alters microbial colonisation in the first days of life, with distinct effects on male and female mice. Males born by caesarean section develop increased susceptibility to colitis in adulthood, while females do not. This difference is linked to changes in gut microbiota and barrier function.
Researchers introduce a new quality-control framework that detects and corrects errors in satellite orbit, clock, and bias information, improving the reliability and availability of real-time high-precision positioning. The method shows improved results in ambiguity fixing rate, incorrect fixing rate, and convergence rate.
Researchers found that targeting highly connected peers produced the largest reductions in smoking, with influence extending up to three degrees of separation. Social network structure also mattered, with denser networks showing wider and slower diffusion.
New research reveals that kangaroos' thick tooth enamel allowed them to efficiently feed on grasses, unlike other herbivores. This unusual adaptation likely played a key role in their success, as they outcompeted extinct marsupials with similar dental features.
A study involving nearly 3,000 US participants found that the new CDC statement increased concerns about vaccine safety and decreased willingness to get vaccinated. The researchers recommend transparent and evidence-based communication by health authorities to maintain trust and avoid science denial.
The malaria parasite uses its own messenger RNA to disrupt the host's immune system, causing chaos and evading detection. By inserting its mRNA into monocyte nuclei, the parasite jams internal communications, shutting down immune protein production and triggering an immune response that fails to detect the parasites.
A study found that wild sulphur-crested cockatoos learn about novel food through social learning, with juveniles more likely to conform to the majority's preferences. The birds' dietary knowledge spread rapidly through their community, influenced by age groups and sex.
Physicists from Heinrich Heine University and Forschungszentrum Jülich successfully accelerated polarized Helium-3 ions using laser-plasma acceleration. The preserved spin alignment increases reaction probability in controlled nuclear fusion, a crucial step towards energy production.
A team of researchers from MIT has directly characterized the three-dimensional atomic structure of a relaxor ferroelectric for the first time. This breakthrough provides a framework for refining models used to design next-generation computing, energy, and sensing devices.
A recent CDC policy change emphasizing uncertainty has been shown to increase perceived vaccine risks, reduce vaccination intentions, and lower trust in the CDC. The experiment found that participants exposed to an uncertainty-based message were more receptive to science-denial strategies.
Scientists identify Lockin, Sequestin, and Acb5 protein families in phages, revealing how viruses silence bacterial immune systems. These findings shed light on the importance of communication disruption in the billion-year-long war between viruses and bacteria.
A study by SWPS University found that people with depressive symptoms use less active language, such as 'I am incapable' instead of 'I achieve goals'. This analysis of social media posts shows promise for early detection and prevention of depression.
A new study shows that large language models (LLMs) excel in physicians' clinical reasoning tasks, including emergency room decisions and diagnoses. LLMs surpassed earlier AI systems in complex cases, but the findings raise questions about their future implementation in clinical care.
An international team of researchers found that coordinated land-use planning can reduce species impact by 15% and carbon loss by 19%. Strategic planning can enable progress toward global biodiversity, climate, and sustainable development goals simultaneously.
Researchers discovered that the microbiome of people living with HIV differs from uninfected controls, changing in response to the progression of the infection. The study suggests that HIV affects the immune system's natural antibiotic molecules, allowing certain bacteria to thrive in the gut.
The report examines how generative AI tools are transforming software development, offering benefits such as increased productivity but also raising security vulnerabilities and technical debt. Strong software engineering practices are still required to ensure systems are secure, reliable, and maintainable.
A new study published in the Journal of Cleaner Production examines the link between corporate political spending and ESG disclosure among S&P 500 companies. The researchers found that firms with higher lobbying expenditures tend to score lower on sustainability transparency, particularly when it comes to environmental disclosure.
Researchers propose a different view on symptoms of illness, suggesting they're part of an integrated immune strategy that helps promote survival. The brain-immune axis is key to this coordinated system, influencing both brain activity and behavior in response to threats.
A study published in Translational Psychiatry suggests that low-dose minocycline may help treat panic disorder by reducing inflammation in brain cells. The antibiotic was found to have a similar effect to the commonly prescribed medication clonazepam, with lower doses required to achieve similar results.
Researchers developed a new method to predict debris flows in post-fire landscapes, incorporating vegetation recovery, which reduces unnecessary warnings and improves accuracy. The updated method reflects changes in soil absorption and plant water uptake after wildfires, providing more accurate hazard maps and rainfall threshold guidance.
The DAMPE satellite has identified a universal feature in the energy spectra of primary cosmic ray nuclei, revealing that spectral softening occurs around a rigidity of about 15 TV. This observation strongly supports models explaining the acceleration and transport of cosmic rays based on their rigidity.
Jupiter is found to be about 8 km less wide at the equator and 24 km flatter at the poles, requiring an updated understanding of the giant planet's size and shape. This research has broader implications for studying gas planets in general and provides new insights into Jupiter's powerful winds and interior structure.
Researchers found that melatonin increased vascularization and reduced apoptosis in ovarian grafts, improving their viability. The study used an absorbable sponge to apply melatonin to autologous ovarian tissue transplants in rats, revealing its potential as a treatment option for fertility preservation in young cancer patients.
A new optimization framework helps food banks deliver food more efficiently by accounting for variables such as food availability and household demand. The tool has been incorporated into an app that can also be used by businesses to address delivery logistics challenges.
A new camera-only visual odometry system uses prebuilt colored point cloud maps to deliver accurate and robust localization in GNSS-challenged environments. The system reduced absolute trajectory error by up to 95% compared to existing methods, while maintaining near real-time efficiency.
Researchers at KAIST have developed a novel diagnostic technology that can distinguish multiple viruses and variants by controlling the speed of CRISPR gene scissors. This method, called kinetic barcoding, interprets differences in reaction speeds as signal patterns to identify different viruses.
A naturally occurring fatty acid called geranylgeranoic acid (GGA) has been discovered to disrupt the ability of MRSA bacteria to stick to human molecules and detect their environment, making it harder for them to cause disease. Researchers tested GGA in mice and found it prevented skin lesions and reduced infection severity.
Researchers found that NRG4, an adipokine secreted by white adipose tissue, suppresses breast cancer metastasis via ERBB4-YAP1 signaling. The study also showed that higher NRG4 levels correlate with improved patient survival outcomes.
A team of 14 West African Master's students, accompanied by experienced scientists, will conduct research at depths of up to 4,900 meters on the POLARSTERN research vessel. The 'Floating University' program aims to document long-term changes in the ocean and investigate marine biodiversity.
Researchers from the University of Birmingham have developed a novel perovskite catalyst that can produce substantial yields of hydrogen in a temperature range of 150-500°C, and be regenerated at temperatures between 700 and 1000°C. The process is more cost-effective than green or blue hydrogen production methods.
A study published in Pediatric Research demonstrated the safety of intranasal breast milk therapy in brain-injured newborns. The therapy was found to be effective in supporting nervous system regeneration without causing any adverse effects.
A study in Nature reveals a sharp increase in wild meat consumption across Central Africa, driven by urban populations. The total annual biomass of wild meat consumed has increased from 0.73 million tonnes in 2000 to 1.10 million tonnes in 2022.
A team of researchers has created the first draft of a genetic interaction map, covering about 2.5% of all possible gene pairs in the human genome. The map reveals conserved principles and potential targets for human diseases, including drug targets and genes mutated in human diseases.
Scientists have successfully sent single, coherent photons in the telecom band, overcoming a long-standing challenge. This breakthrough enables the integration of quantum technology with existing fiber infrastructure, opening up applications for secure communication and computation.
A genetic atlas of a healthy human liver at 2 microns resolution shows eight distinct regions with unique roles, differing from other mammals. The findings help explain why certain liver regions are vulnerable to diseases like fatty liver disease and liver cancer.
Researchers found that improved lighting design combined with modern LED technology can reduce household energy use and enhance comfort. The study showed a 15.3% reduction in energy consumption by optimising lighting planning and positioning using software-based approaches.
A protein called Teneurin 4 directs neuronal migration through mutually exclusive pathways, regulating adhesion to fibres and enabling faster movement. The discovery improves understanding of brain development and offers insights into neurodevelopmental disorders.
Scientists found that the brain adapts to noise-induced damage within 24 hours by increasing excitability and inhibitory inputs in the superior paraolivary nucleus. This enables the restoration of critical timing information for sound processing, despite diminished sensitivity to quieter sounds.
A new publication proposes a polarization-guided diffusion prior model to remove eyeglass reflections. The method, PDPrior, achieves robust removal across diverse scenarios without relying on training data or ground-truth images, resulting in improved face image quality and accuracy.
New technologies are shifting healthcare towards proactive care, using AI for early heart disease detection and miniaturized CRISPR-based diagnostics. These innovations enable seamless integration of existing medical screenings and provide laboratory-grade accuracy in a portable format.
Researchers have discovered that ice has been gradually accumulating on the Moon's poles for at least 1.5 billion years, with ancient 'cold traps' acting as efficient ice-traps for billions of years. The study identifies regions like Haworth Crater as prime targets for future landed missions to find water ice.
A long-term study finds that children in infant care institutions had a 48% higher risk of mortality and shorter life expectancy than those raised at home. The research highlights the importance of affection and stimulation in early childhood, revealing lifelong consequences for those who experienced institutional care.
The new guideline provides evidence-based recommendations for 26 diseases, including pigmentary disorders and skin rejuvenation. The guideline aims to standardize clinical practice in laser and aesthetic medicine, improving treatment outcomes and safety.
Researchers at Garvan Institute of Medical Research discovered key immune cells malfunction in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder. Current treatments targeting inflammatory signals produced by macrophages fail in half of patients, but JAK inhibitors may provide relief.
A large cohort study found a modestly increased risk of nonarteritic anterior ischemic optic neuropathy associated with GLP-1 receptor agonist use. In contrast, SGLT2 inhibitor use was not linked to an increased risk. The findings warrant heightened vigilance for GLP-1 RA users.
Researchers have captured an unprecedented view of gene transcription by observing RNA polymerase mid-reaction. The findings provide a universal blueprint for gene expression and clarify how the enzyme initiates its core reaction through a water-mediated mechanism.
The LHAASO collaboration has detected ultra-high-energy (UHE) gamma rays from a gamma-ray binary system, LS I +61° 303. The discovery suggests that high-energy protons are accelerated and collide with the dense surrounding stellar wind, producing these UHE gamma rays. This finding provides critical evidence for gamma-ray binaries as po...
A new study found that targeted maternal screening can prevent adult T-cell leukemia/lymphoma, a rare and aggressive cancer caused by human T-cell leukemia virus type 1. The research identified high disease rates among non-Hispanic Caribbean-born US residents, particularly in Florida and New York.
Researchers have discovered a new weight-loss mechanism that eliminates the need for GLP-1, reducing gastrointestinal side effects and increasing treatment tolerability. This breakthrough offers hope for patients who struggle with adverse reactions to existing obesity medications.
Researchers at Vanderbilt University Medical Center discovered that enterotoxigenic Bacteroides fragilis reshapes intestinal cell metabolism to support its growth, causing diseases like diarrhea and colorectal cancer. The study provides new possibilities for intervention by targeting metabolic interactions between host and microbes.
Researchers propose atomically dispersed U−O−Ti bimetallic active sites for high-efficiency PEC OER catalysis, achieving a 3.82-fold enhancement compared to pristine TiO2. The material exhibits excellent structural stability and operational safety.
Researchers have developed a non-toxic, stretchy hemp-derived thermoplastic that can extend up to 1,600% of its size. The material has a high glass transition temperature, making it suitable for producing transparent plastic films, coatings, and other common materials currently made from petroleum-based materials.
New models reconstruct the movement of faults during the 8.8 magnitude Kamchatka earthquake, revealing limited shallow rupture and affecting tsunami risk. The study provides valuable insights into predicting giant earthquakes and protecting coastal communities.
Researchers developed an interfacial buffering strategy to address solvent-induced damage in pseudo-planar heterojunction organic solar cells, achieving a power conversion efficiency of 20.21%. The buffer layer preserves the structural integrity of the donor layer and maintains a well-defined heterojunction interface, facilitating effi...
Researchers developed a highly homogeneous population of stem cell memory T cells that exhibit superior expansion and persistence, enabling complete responses at low doses. The study showed a favorable tolerability profile and demonstrated the separation between beneficial effects and toxic consequences.
Researchers used cryo-electron microscopy to visualize individual water molecules and metal ions within RNA polymerase II, revealing their active role in DNA transcription. The study provides a new understanding of how genetic information is read and expressed, challenging the traditional 'protein-centered' view.
Termites became the backbone of tropical ecosystems after two diversification pulses following global extinctions. The traits that define modern termites, such as soil-eating and fungus agriculture, emerged in distinct pulses about 30 million years apart, according to a new study published in Current Biology.
Researchers have identified a gene, eIF4G2, crucial for keeping adult intestinal stem cells stable and functional. The study reveals that the gene plays a vital role in regulating protein production and maintaining stem cell identity.
Researchers found that suppressing the Integrated Stress Response (ISR) pathway in fruit flies extended their lifespan. The study contradicts previous theories suggesting mild stress might increase longevity. By understanding how ISR affects aging, scientists may develop pharmacological treatments to slow down the aging process.
A new study from Karolinska Institutet found that small abnormalities in blood sugar, lipids, and inflammation years before pregnancy are associated with an increased risk of high blood pressure during pregnancy and pre-eclampsia. The findings may contribute to earlier risk assessment and preventive measures.
A study analyzing 2,668 angiosperm species found that evolutionary relationships explain the largest share of variation in fruit volume. Climate influences this pattern, with temperature modulating phylogenetic constraints on fruit volume in different plant groups.
A new strategy has created 'living plastics' that self-destruct on command, using activatable microbes to break down material within a week. The breakthrough could lead to the development of triggerable spores in water to tackle plastic pollution.
The University of California and JMIR Publications have extended their institutional membership agreement, reinforcing a commitment to advancing open science. The multi-year extension supports over 450 articles published under the agreement, making open access publishing more equitable for UC researchers.
The University of Oldenburg is building a unique research facility to study animal navigation and magnetoreception. The NaviGate building will offer conditions worldwide for addressing current questions in animal navigation research, sensory biology, and neurosensorics.
The university generated an 8% increase in economic activity, creating 12,603 jobs statewide and supporting a regional economy of $1.69 billion. Binghamton University's expansion and student spending also contributed to the growth, with faculty members holding top degrees in their fields.
Snow cover on Greek mountains has declined by 58% over the past four decades due to rising temperatures. The research found that warmer air causes more precipitation to fall as rain instead of snow at high altitudes.
Researchers identified a new class of Streptomyces-produced toxins that are toxic to insects but not humans, with potential applications in medicine, agriculture, and biotechnology. The discovery suggests ancient bacteria may have played a role in shaping human disease.
Researchers analyzed genetic data from 1.4 million women, identifying 80 genome regions linked to endometriosis. The study provides a comprehensive view of the disease's pathophysiology, highlighting its complexity and multiple contributing biological processes.
Researchers have developed a nanoscale tool that can capture and precisely position membrane proteins, essential for life and target of many modern medicines. The DNA Origami-Constrained Nanodiscs (DOC-NDs) approach combines two advanced techniques to create tiny structures that hold individual proteins with remarkable accuracy.
A new study reveals that wildfires in the Western US have decreased by 28% over the past three decades, with fires starting from natural causes declining more than those caused by humans. The findings suggest that higher population densities lead to fewer fires, while adding people to less populated areas makes blazes more common.
A physics-inspired model suggests that spending above $1.8 million in US House races leads to increased polarization without changing the election outcome. Below this threshold, social dynamics shape outcomes, while higher spending only deepens polarization.
Researchers developed a lattice-matching strategy to address charge transfer efficiency and selectivity issues in traditional photoelectrocatalytic systems. The resulting composite photoanodes achieve high DHA selectivity and glycerol conversion rates, demonstrating strong potential for industrial application.
A new study from Virginia Tech found that task switching in transplant surgeries increases one-year mortality rates by 14.8 percent, highlighting the need for efficient scheduling and workflow changes to minimize risks. The research also suggests that recovery time and surgeon experience level can mitigate these effects.
A new study uses local news to assess wildlife poaching in Romania, revealing the roe deer as the most frequently poached mammal. The research highlights a darker side of human-wildlife conflict and underscores the need for community mindset shift and policy reform.
A new photocatalytic system with enhanced activity for benzimidazole synthesis and H2 production has been developed. The defect-engineered Pt/Nb2O5-VO photocatalyst promotes dehydrogenation of ethanol to form radicals, which then facilitate the selective synthesis of desired products.
A new tool can predict an individual's risk of developing 18 obesity-related diseases, identifying those at highest risk for earlier intervention. The OBSCORE model uses 20 commonly collected health measures to provide a more accurate and personalized way to identify individuals at higher risk.
Researchers at CUNY ASRC have uncovered a metabolic switch that influences the formation of myelinating cells, helping shape brain development. The study reveals that glucose levels act as a signal directing behavior during development and can be harnessed to protect myelin in the developing brain and promote repair in disease states.
The study demonstrates that the T1GRS tool can identify children and adults at high risk for Type 1 diabetes earlier than current methods, enabling preventive measures before the disease develops. The researchers grouped individuals into four sub-types based on genetic features, each with unique clinical profiles and outcomes.
A new UN Women report reveals that online violence and deepfakes are pushing women out of public life, with alarming rates of mental health diagnoses and self-censorship. The study also found that law enforcement is often failing to provide justice for survivors, highlighting the need for effective education and training.
A new universal model explains and guides energy level alignment in perovskite solar cell interfaces using hole-collecting monolayers, enabling optimized interfacial energy levels and reduced development time. The study provides practical guidance for designing materials with improved performance for emerging solar technologies.
A new catalyst developed by Soochow University researchers exhibits a remarkable C2+ Faradaic efficiency of 80.3%, outperforming other Cu-based catalysts. The introduction of carbene species enhances the tandem synergy, increasing surface coverage of CO intermediates and facilitating C-C coupling reactions.
Research suggests that vaping is associated with increased odds of quitting smoking, but this relationship may not be true for everyone. Daily vape use was a stronger predictor of successful cessation than intermittent or no use.
The American Thoracic Society has launched a quality improvement initiative to tackle the underdiagnosis of bronchiectasis in the US. The study aims to investigate the scope of the problem and drive meaningful change in how the disease is identified and managed.
A team of researchers has identified a key mechanism in the degeneration of motor neurons in ALS, revealing that chaperone-mediated autophagy is significantly reduced in patients. This finding suggests that this cellular system may be a potential therapeutic target to slow disease progression.
Researchers found that camels have a more flexible and coordinated response to heat stress, allowing them to maintain stability even at higher temperatures. In contrast, human cells tend to respond in a more rigid way, making them less adaptable under heat stress.
Researchers identify previously unknown 'in-between' materials that can be used to design better solar fuels, batteries, and catalysis materials. The study reveals a series of hidden intermediate stages during heating, opening up new opportunities for material discovery and development.
A new study found that fur seals' heart rate peaks six to eight hours after returning to land, indicating a delayed recovery from the physiological costs of foraging at sea. This suggests that seals use their time onshore to actively recover and replenish oxygen stores.
Research suggests that cultural foreignness stereotypes can lead to job discrimination against Asian, Arab and Latino American applicants. In experiments, participants rated these groups as less hirable than Black American candidates with similar resumes.
Researchers discovered that interictal epileptiform discharges (IEDs) occur in a predictable pattern, unfolding sequentially in individual neurons. Nearly 80% of IED-involving neurons are also involved in language and perception, suggesting the brain blips can derail cognition.