About The Study: In this large cohort study, glucagon-like peptide-1 receptor agonist (GLP-1RA) use was associated with a modestly increased risk of nonarteritic anterior ischemic optic neuropathy compared with sodium-glucose cotransporter-2 inhibitor (SGLT2i) use. While the absolute risk remains low, the specificity of this finding may warrant heightened vigilance.
Corresponding Author: To contact the corresponding author, Yan Xie, PhD, email yan.xie3@va.gov .
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(doi:10.1001/jamanetworkopen.2026.9917)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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