A long-standing scientific consensus holds that vaccines are not associated with autism. However, a recent shift in messaging by the U.S. Centers for Disease Control and Prevention (CDC) moved from emphasizing this consensus to highlighting uncertainty, potentially implying that a link has not been fully ruled out. Although this policy change could have significant consequences for public health, its effects on how people think, feel, and act regarding vaccination remain poorly understood. Moreover, moving from a clear, evidence-based consensus to messaging that emphasizes uncertainty may do more than influence vaccine decisions, it can also contribute to wider social effects, such as deepening political divisions, weakening trust in institutions, and making individuals more receptive to dismissing scientific evidence, especially in areas where experts largely agree. In this Policy Article, Bohm et al. conducted an online experiment using an opt-in sample of 2,989 U.S. adult participants. Participants were randomly exposed to either a consensus-based or uncertainty-based CDC-style statement, and their responses were measured. They found that exposure to the uncertainty-based message increased perceived vaccine risks and uncertainty, reduced vaccination intentions, lowered trust in the CDC, and increased endorsement of science-denial strategies. These effects occurred regardless of participants’ political orientation. “Overall, the findings underscore the responsibility of public health institutions to communicate scientific uncertainty in ways that protect, rather than inadvertently weaken, population health,” write the authors.
Science
CDC communication undermines trust in vaccines
30-Apr-2026