A research team at Niigata University has identified a copper-HIF1α-BNIP3-mTOR pathway connecting trace elements to glial cell development in autism spectrum disorder. Lower plasma copper levels were associated with higher ASD symptoms and reduced white matter volume, which was linked to social symptoms.
Researchers have identified an active fault along the Hunua Ranges in South Auckland with a high potential for a major earthquake, posing serious consequences for people living in the region. The Mangatangi Fault has ruptured within the past 10,000 years and is considered an active fault due to its movement in the past 125,000 years.
Researchers from The University of Osaka found that treatment with five mRNAs effectively promoted cardiac repair and extended survival in mice with heart failure. The study showed that simultaneous administration of five therapeutic mRNAs reduced heart tissue damage and improved heart function.
Scientists have created a highly efficient Mn-based catalyst for ammonia synthesis, overcoming scaling relationships and improving performance. The new catalyst enables N₂ dissociation through a hydride-assisted mechanism, resulting in higher ammonia synthesis rates.
CURE SYNGAP1 invests in remote assessment tools to broaden access to clinical care and trials for patients with SYNGAP1-Related Disorders. The study aims to evaluate the validity of a standardized remote developmental assessment to reduce travel burden.
A groundbreaking study created a world's first pure cerebral microbleed model by targeting brain vascular collagen IV using CRISPR/Cas9 gene editing. The research implicated dysfunctional collagen in tiny brain hemorrhages, which are strongly associated with dementia and cognitive decline.
The conference features parallel sessions covering electronic and information-processing materials, energy storage and conversion, biomaterials, high-performance metallic materials, AI-driven materials discovery, and advanced characterization techniques. Registration is now open for the event.
Researchers developed smart-responsive superwettable materials for efficient oil-water separation, achieving high efficiency and reversibility. The materials combine selectivity of static membranes with adaptability of living biological systems.
Researchers at POSTECH develop technology that lowers contact resistance by 50-fold and boosts on-state current by 17 times in ultra-thin tellurium transistors. This breakthrough enables stable operation of devices even at extreme temperatures, paving the way for next-generation 3D integrated circuits.
Researchers observe Eurasian Hobbies feeding on bats in a protected wetland in Greece, highlighting the importance of local prey populations for migratory raptors. The study's findings have strong conservation implications and demonstrate the need to protect habitats and prey species.
The CURE SYNGAP1 COLLECTIVE is a collaborative framework uniting independent SYNGAP1 charities worldwide to accelerate treatments for individuals with SYNGAP1-Related Disorders. The Collective focuses on three primary pillars: research, industry engagement, and patient advocacy.
Biochar can restore acidic tea soils, reduce toxic metal uptake, and support climate-smart cultivation. It also improves fertilizer use efficiency, supports biochemical pathways linked to tea quality, and reduces heavy metal exposure risks for consumers.
A new study found Turkey Vulture populations increasing by almost 300% over 25 years, with delayed migration departure dates. This could be linked to climate change, which researchers hope will inspire further investigation.
Two University of Utah-led studies aim to improve biomass mapping to better understand how Arctic and boreal forests respond to climate change. The new maps, built using satellite imagery and field measurements, capture 40 years of ecological change in unprecedented detail.
A new five-year field study suggests that pairing annual biochar amendment with water-saving irrigation can reduce methane emissions from paddy fields. Continuous biochar use maintained and strengthened methane mitigation over time, while a one-time application's effect weakened.
Research by Cheryl Dykstra and her team found a correlation between higher quality territories and the proportion of female nestlings. The study also revealed that solitary young are more likely to be female than male, with eggs laid later in the season increasing the probability of hatching into a male.
A new study from UC Santa Barbara reveals that the number of roads out of a community may be one of the strongest predictors of wildfire fatalities. Communities with six or fewer exits have a sharp drop in fatalities, while additional roads offer little further protection.
Researchers found that higher soil salinity can slow biochar's aging process, preserving its carbon content and reducing microbial activity. This study provides new insights for sustainable management of saline farmland and highlights the importance of microorganisms in shaping biochar's environmental functions.
A study by Radboud University Medical Center found that 75% of patients with stable psoriasis can safely reduce their biologic medication dosage by half, achieving similar symptom control. This reduction in dosage leads to fewer injections and saves up to €8,500 per patient per year.
UW researchers found that most biology education guidelines lack connections to society, with only 7% of elements discussing ethics and public health issues. This can lead to a lack of engagement and retention among students, as real-world examples support their interest in science and help develop their scientific identity.
A new UCLA-led study found that nursing homes in states with COVID-19 malpractice lawsuits protections had 2.5% fewer staff members compared to those without such protections. This resulted in an average of almost 8 hours less staff conducting clinical care and other duties per nursing home.
A new study from the University of Oxford found that drought exposure is associated with increased risk of sexual, emotional and physical violence among adolescents in Southern Africa. Girls and young women face the highest risk of violence during drought conditions.
A new book by a Cambridge child psychotherapist argues that treating parents alongside children is crucial for addressing the youth mental health crisis. The author highlights the importance of considering an 'ecological system', including families, communities, and environment, in understanding young people's wellbeing.
The convergence of traditional and decentralized finance is breaking down barriers to financial access worldwide, particularly in emerging economies. Tokenisation is enabling essential infrastructure, including cryptocurrency payments and investment opportunities previously exclusive to the ultra-wealthy.
A newly developed portable point-of-care PET technology provides high-quality results for guiding biopsies, tumor ablations, and other interventional procedures. The bedside device offers real-time visual feedback, making it a cost-effective approach for hospitals to perform procedures in constrained clinical environments.
A new study from the University of Exeter found that genetic testing can identify the cause of pancreatic agenesis in 98 per cent of cases. This diagnosis allows healthcare professionals to provide families with a better understanding of the condition's impacts, risks, and help them find support.
Mount Sinai researchers have uncovered a substantial genetic component to postpartum psychosis, a rare psychiatric illness that occurs after childbirth. The study found rare damaging mutations in the HMGCR gene and significant genetic overlap with bipolar disorder, schizophrenia, and autoimmune diseases.
A large survey of US adults found that support for political violence remained stable from mid-2024 to mid-2025, with most Americans rejecting violence across all political affiliations. The study's findings suggest that prevention efforts can benefit from recognizing both areas of concern and resilience.
Researchers have developed custom 4D-printed implants that expand slowly and steadily, reducing the need for repeated injections and surgeries. The devices were tested in rabbits and showed promising results, including improved skin adaptation, reduced complications, and increased precision in reconstructive surgery.
A new PET tracer targeting carbonic anhydrase IX (CAIX) has demonstrated exceptional sensitivity and high tumor-to-background contrast in detecting clear cell renal cell carcinoma (ccRCC). The tracer successfully identified additional metastatic lesions missed by standard imaging while reducing abdominal background noise.
Thawing permafrost is causing Arctic rivers to turn toxic with orange iron particles, suffocating insects and smothering fish. The process also involves acid rock drainage, where pyrite breaks down into sulfuric acid and sulfate, creating rust-like particles.
A new study found that nearly a quarter of adults with a normal weight BMI may still be at risk for obesity-related health complications. The research highlights the importance of considering multiple factors beyond body mass index (BMI) to accurately identify individuals at risk for these conditions.
A study found that BMI significantly understates obesity levels in the US, with up to 50% of overweight individuals reclassified as obese under a new clinical definition. This highlights the need for healthcare providers to adopt this new measure to better identify and treat obesity-related health risks.
A novel PET imaging framework reveals bariatric surgery induces coordinated changes in metabolic function across organs, including fat, liver, pancreas, muscle, and immune-endocrine organs. These findings support the use of whole-body PET/CT as a tool to map organ-level metabolic health.
Deep brain stimulation (DBS) can remodel white matter pathways in the brain and alter communication across large-scale neural networks. The therapy helps patients recover from severe depression by increasing fractional anisotropy and myelination within specific pathways, suggesting a previously unrecognized mechanism.
Over two decades, Biscayne Bay has become warmer, saltier, and more acidic due to climate change, threatening South Florida ecosystems. The study analyzed water quality observations collected between 2001 and 2021, finding significant increases in salinity and declining pH levels.
Research on deer mice reveals a unique gene family, Phf8y, that acquired from the X chromosome and duplicated itself on the Y chromosome. This discovery provides insights into how the Y chromosome defends against decay and maintains fertility in males.
Andrew Yang's research has reshaped scientific understanding of the blood-brain barrier and its role in brain health and disease. His latest study reveals new potential treatment targets for neurological diseases, normal aging, and sleep.
Researchers at Rice University have developed a noninvasive method to track the expression of specific genes in living brain tissue, enabling real-time monitoring of gene activity. The tool, called In-vivo Tracking of Active Transcription (INTACT), uses engineered reporter molecules and sensors to detect target mRNA in the bloodstream.
Researchers found coordinated brain activity linked to social behavior begins seconds before movement starts in zebrafish. The pallium plays a key role in generating social drive, with stronger neural signatures predicting more socially engaged individuals.
The LEGO Foundation Fellowship will support up to 10 researchers pursuing ambitious work on how children thrive in crisis and conflict settings, neurodivergent children, and AI-enabled learning. The fellowship aims to deepen understanding of what helps children learn, grow, and thrive.
A new study from Northwestern University reveals American voters are more accepting of gay candidates than ever before, but acceptance is conditional and varies by political party. Republican voters continue to penalize candidates for being gay, while Democratic voters punish those who look or sound slightly gender nonconforming.
The study found that adjuvant nivolumab did not improve disease-free survival in patients with resected non–small cell lung cancer. The treatment was also not effective in sensitizing EGFR and ALK alterations.
The Healthcare Infection Prevention Advisory Group (HIPAG) aims to address gaps in infection prevention expertise and support evidence-based practices. HIPAG will provide national expertise on antimicrobial resistance, emerging infectious disease threats, and frontline healthcare operations.
Researchers analyzed tumor samples from over a thousand patients and found that TP53 gene mutations can worsen prognosis and reduce effectiveness of targeted therapies. The study suggests incorporating genetic testing into public health services to guide personalized treatment choices.
Current evidence suggests P2Y2 signaling is associated with multiple cancer-related processes, including cell proliferation, migration, and EMT. The receptor has also been linked to intracellular signaling pathways such as EGFR, PI3K–AKT, and MAPK.
A new PET radiotracer can effectively image overactive adrenal glands, allowing for a non-invasive approach to diagnose primary aldosteronism. This could enable physicians to tailor treatment plans for patients with this condition.
Adding fovinaciclib to first-line aromatase inhibitor therapy confers significant progression-free survival benefits and consistent improvements in efficacy outcomes. The treatment also has manageable safety profiles with no negative impact on quality of life.
A new study by the Max Planck Institute for Chemistry finds that accelerating renewable energy expansion can effectively close the energy supply gap while providing climate change mitigation benefits and improving public health. This creates substantial societal and economic benefits, outweighing the costs of renewable energy expansion.
A recent study revealed that the bacterial pathogen Flavobacterium columnare remodels its epigenetic landscape during prolonged starvation, rather than altering its DNA sequence. This finding suggests a novel survival strategy for the bacterium and could have direct implications for aquaculture disease control.
A recent study by Karolinska Institutet researchers found that semantic knowledge plays a vital role in human innovation, enabling individuals to create new connections between objects and ideas. The study showed that groups with access to both semantic knowledge and social learning produced more unique innovations than those with only...
A recent study found that hormone therapy use among US women has steadily declined from 4.4% in 2007 to 1.7% in 2023, despite its proven benefits for symptom relief and quality of life. The majority of women who could benefit from hormone therapy are not receiving it due to misconceptions about risks and limited training among clinicians.
Researchers at Stevens Institute of Technology discover that mature gut cells can revert to cancer-driving stem cells, explaining why colorectal cancers are resistant to treatment. This finding suggests pathways for effective therapies and sheds light on the complex cellular environment of the intestines.
The American Heart Association and Houston Texans trained nearly 100 youth sports coaches in CPR and AED use, gaining hands-on experience to recognize cardiac arrest. Without immediate CPR, more than 90% of people who experience cardiac arrest outside a hospital do not survive.
Researchers used magnetic particle imaging to track cell therapy injections in mice, finding that it can visualize therapeutic cells as they inject them. The technique shows promise for developing more effective treatments for certain cancers, autoimmune diseases like MS, and neurological conditions.
A research project led by University of Tennessee at Knoxville associate professor Candace Brakewood aims to evaluate the impact of congestion pricing on public transit systems. The study will focus on New York City's recent implementation, analyzing how it increased transit ridership across subway, bus, and regional rail systems.
Researchers created the first 3D map of heart's electrical wiring in Tetralogy of Fallot, a common congenital heart problem. The map reveals anatomical features that may explain heart conduction disorders in this condition.
The symposium brought together a diverse pool of medical researchers to share groundbreaking studies on emerging technologies in medicine. The event highlighted pioneering approaches that are transforming patient outcomes, showcasing how Hackensack Meridian Health is paving the way for novel therapies.
Researchers at USC Dornsife College of Letters, Arts and Sciences have developed a new framework to understand how marine microbes grow, compete, and recycle carbon around the globe. The study identifies eight metabolic groups that help explain how microbial communities vary across the ocean.
A new web tool, FishCast, helps forecast drought impacts on trout populations and support fisheries and water management in Montana's blue-ribbon rivers. The tool integrates weather information, historic trout population data, and streamflow records to predict drought risk and trout population trends.