A new study by Columbia University researchers introduces four novel metrics to assess progress on gun violence prevention, highlighting the decline of shooting-free days in major US cities. The study suggests that these metrics can identify protective conditions and inform policy to sustain longer periods without firearm violence.
Researchers mapped PARP inhibitors' distribution using advanced imaging techniques and patient ovarian tumour samples, revealing that build-up of drugs in lysosomes can trap and release certain drugs over time. This mechanism increases exposure to cancer cells, leading to variable treatment responses.
Scientists at Georgetown University have found that ezrin's closed form binds to RNA, influencing gene translation and supporting cancer cell growth. The discovery may lead to new treatments for osteosarcoma and other ezrin-dependent cancers.
Charles Thorn has made significant contributions to the field of theoretical physics, including the development of string theory and the no-ghost theorem. He was awarded the 2026 Dannie Heineman Prize for Mathematical Physics for his fundamental contributions to elementary particle physics.
Researchers engineered Escherichia coli Nissle 1917 bacteria to produce anticancer agent Romidepsin, which was released from the bacteria and effectively targeted cancer cells in mouse models. The study establishes a solid foundation for bacteria-assisted tumor-targeted therapy, paving the way for future advancements in cancer treatment.
The OSIRIS-REx mission has found that asteroid Bennu's boulders are cracked, not porous as initially thought. This discovery transforms our understanding of how to interpret an asteroid's thermal properties from Earth-based observations.
Researchers at NJIT analyzed nearly three decades of solar oscillation data to trace the Sun's magnetic engine, revealing a butterfly-shaped flow pattern in the deep solar interior. The findings point to the likely location of the star's magnetic engine deep beneath its surface, roughly 200,000 kilometers down.
A study of 2,000+ participants found nine specific gut microbe metabolites associated with coronary heart disease risk. The researchers call for further research into these molecules as potential novel treatments.
A study found that 44% of respondents were open to trying insects, while 27% were willing to include them in their regular diet. Curiosity and perceived health benefits were key motivators, while disgust and fear were major barriers. Presenting insect-based products in a appealing way can help increase acceptance.
A new study published in the JAMA Network found that older adults take more than 6 months to recover from surgery, with nearly 20% still experiencing impairments in activities of daily living. The study highlights the need for better post-operative planning and guidance to support the recovery process.
Researchers found that reduced IGFBP6 protein levels in tumours lead to macrophage accumulation, increasing risk of cancer recurrence. They propose targeting the tumour microenvironment with therapies aimed at fibroblasts and IGF2 production.
Researchers integrated transient optical spectroscopy with ultrafast electron microscopy to capture both electronic and structural dynamics simultaneously. This enables the study of heterogeneous materials, phase transitions, and light-driven functional responses with implications for solar cells, quantum computing, and next-generation...
Researchers developed a new photocatalyst that can efficiently remove fulvic acid from drinking water using sunlight. The catalyst, combined with persulfate, achieved 98.43% fulvic acid removal in 30 minutes, with broad activity against various pollutants.
A new study reveals hidden ocean heatwaves in the South China Sea, threatening biodiversity and fisheries. The research team identified the northeastern basin as a persistent hotspot, with heat transport from the Kuroshio amplifying subsurface warming.
Researchers discovered native fungal species in almond trees that can naturally suppress anthracnose disease, providing a sustainable alternative to chemical fungicides. The study identified Trichoderma viridescens and Neurospora intermedia as promising biofungicide candidates.
Cactus Communications has been awarded the 'Committed Badge' by EcoVadis, recognizing its over 50% year-on-year improvement in ESG performance. The company's commitment to building responsible business practices aligns with UN SDGs and creates long-term value for stakeholders.
A study led by Dr. Marco Milán identified mitochondria as a key player in a rare disease causing microcephaly, a condition where the brain develops to a smaller size. The researchers found that mitochondria dysfunction leads to proteotoxic stress, causing cells to accumulate errors in chromosome distribution, resulting in microcephaly.
A new search robot developed at the Technical University of Munich (TUM) uses a combination of spatial maps and language models to efficiently find objects in dynamic environments. The robot can build a three-dimensional image of its surroundings and update it constantly, allowing it to search for objects with a high degree of accuracy.
Humification of lignocellulosic biomass enhances soil organic carbon accumulation and stimulates microbial carbohydrate-active enzyme genes, while also promoting the enrichment of antibiotic resistance genes, particularly under higher phenolic concentrations. This trade-off highlights the need for balanced residue management strategies...
A team of researchers has found that nonmagnetic impurities can help reveal Majorana zero modes, a promising building block for quantum computing. By shifting energy levels, these impurities make the mode's spectral peak more distinct, allowing clearer detection.
Stanford researchers have developed a novel 'scaffold-free' approach for treating damaged muscles, enabling the delivery of more healing cells to the traumatized area. The approach uses a custom molding technology to create dense muscle tissue in customizable geometric shapes and sizes, allowing for more effective muscle regeneration.
Researchers developed a new multiview DNN structure to capture complex 3D anatomy and physiology from multiple imaging views, improving diagnostic accuracy for cardiovascular conditions. The approach demonstrated better performance than single-view DNNs and provided a viable alternative for other medical imaging modalities.
INFORMS celebrates the election of John-Paul Clarke and Oleg Gusikhin to the National Academy of Engineering for their pioneering research and transformative contributions to engineering and society. The recognition highlights their outstanding advancements in engineering research, education, and practice.
A comprehensive study using integrated genomic approach resolves Hylodesmum's taxonomic uncertainties and EA-ENA disjunct distribution. The study confirms Verdesmum as nested within Hylodesmum and reveals a complex bidirectional dispersal pattern likely facilitated by mammal-mediated epizoochory.
Researchers at Case Western Reserve University are working on sustainable packaging solutions to reduce food spoilage and plastic pollution. The team is developing advanced nanocomposite materials that can help food stay fresh longer while reducing environmental impact.
A study by UC3M found that children from privileged families show greater cognitive effort, but incentivizing rewards can narrow the gap. Classroom incentives can help reduce socioeconomic inequalities by valuing individual progress and rewarding social recognition.
A groundbreaking study has identified a molecular pathway in the brain crucial for working memory, revealing the Munc13-1 protein's role in temporarily strengthening synapses to retain information. Disruptions to this protein have been linked to neurodevelopmental disorders, highlighting its importance in healthy brain function.
Researchers used nonlinear dynamics to explore why eczema flare-ups happen and how to improve treatment outcomes. They found that small physiological changes can significantly increase the maintenance burden in long-term efforts to keep eczema in remission.
Researchers have developed a 3D electrode inspired by an aquatic plant, which captures and transports gas bubbles to increase hydrogen production. The design achieved a current density eight times higher than common flat electrodes, collecting 53.9% more hydrogen.
A new 'rock clock' has been developed to date major climate events from the Cambrian Period, allowing precise constraints on the timing of environmental changes. This advancement enables the determination of the timing and duration of the DrumIan Carbon isotope Excursion (DICE), a major global climate disturbance.
A study reveals how sludge-derived hydrothermal byproducts alter periphyton communities, reducing ecosystem multifunctionality and microbial network complexity. HAP's nutrient-rich properties also pose ecological risks, highlighting the need for careful optimization and monitoring to ensure sustainable nutrient recycling.
A study published in Agricultural Ecology and Environment demonstrates that co-pyrolysis of cotton straw and plastic mulch can significantly reduce carbon emissions and agricultural plastic pollution. The process generates biochar, which enhances soil quality and resource use efficiency, supporting sustainable cotton production.
Researchers have identified fungal proteins that can catalyze ice formation at high subzero temperatures, making them a potential alternative to toxic silver iodide in cloud seeding. The discovery could lead to safer weather modification and improved food preservation techniques.
Researchers found that closing eyes impairs hearing in noisy environments, while visual engagement improves sensitivity. Visual engagement helps anchor the auditory system to the external world.
A randomized clinical trial investigated the effectiveness of low-use vs high-use physical restraint strategies in critically ill patients receiving mechanical ventilation in the ICU. The study found no significant reduction in days free of delirium or coma at 14 days, regardless of the restraint strategy used.
Two-year-olds exhibit surprisingly good understanding of turn-taking in conversations, predicting when someone else will speak. Children with Developmental Language Disorder (DLD) also understand when it's their turn, but may be slower to respond.
A new species of leaf warbler, Tokara Leaf Warbler, has been discovered in Japan through DNA analysis. The species is found only on two island groups and is considered vulnerable due to low genetic diversity and potential population declines.
Researchers at RMIT University developed a smart bandage that monitors wound infections and delivers healing therapeutics in one simple dressing. The dressing uses carbon dots to sense pH changes in the wound and combat inflammation, allowing for real-time monitoring and treatment.
A single blood test can accurately forecast the future risk of six major cardiovascular diseases with CardiOmicScore, a novel AI-based tool developed by HKUMed. The system captures subtle biological changes and provides early warning signals up to 15 years before clinical onset.
Researchers from Flinders University emphasize the need to consider mental and physical health, school performance, and digital literacy when evaluating the ban's success. They also warn that restricting access may have limited impact unless platforms build safer environments.
A new study finds that multilateral development banks are failing to adequately address environmental and social risks in green hydrogen projects. The current guidelines lack hydrogen-specific criteria, leaving critical policy gaps.
Scientists have developed a light-activated material that can convert carbon dioxide into carbon monoxide, a key building block for fuels and chemicals, using sunlight and water. The material, which combines ideas from biology and materials science, produces CO extremely efficiently with no detectable by-products.
Researchers discovered that three anesthesia drugs, propofol, ketamine, and dexmedetomidine, have the same destabilizing effect on the brain, causing a loss of consciousness. This common mechanism could lead to the development of a universal anesthesia-delivery system to monitor patients more effectively.
A new study from Michigan Medicine found that over 7% of Americans have thought about shooting someone, while 8.7 million adults considered it in the last year. Firearm owners were no more likely to have these thoughts than non-owners, but 21% of those who had thoughts said they would consider giving their gun to someone for safekeeping.
Researchers break thickness limit for lead-free films, discovering a metastable phase that unlocks latent piezoelectric potential. The films exhibit a piezoelectric coefficient four times higher than conventional forms, paving the way for ultra-miniaturized sensors and devices.
Researchers at Chalmers University of Technology have developed a new material design that enables superconductivity to operate at higher temperatures and withstand strong magnetic fields. This breakthrough could pave the way for far more energy-efficient electronics and quantum technologies.
Researchers analyzed 11,000-year-old bowhead whale fossils to reveal the devastating impact of commercial whaling on the species' genetics. The study found that genetic diversity will continue to decline, severely impacting the species' resilience to climate change.
A team of researchers developed a fully biodegradable and compostable soft robotic electronic system that maintains high performance and durability during operation yet completely returns to nature after use. The system was made from a water-free biodegradable elastomer and integrated biodegradable inorganic electronic components, exhi...
Researchers suggest changing flight paths to avoid contrails could slash aviation's global warming impact by nearly half. Implementing such a policy could recover around 9% of the temperature budget the world has left before breaching the Paris Agreement's 2°C limit.
Scientists at Linköping University successfully created quantum bits using perovskite materials, overcoming previous theoretical limitations. The breakthrough enables the creation of more affordable quantum computers with improved scalability.
A specialized AI model, AMIR-GPT, has been developed to improve radiology guideline alignment, outperforming general purpose models in 33.3% of test responses. However, the model's performance varied across performance bands, and qualitative review revealed limitations, such as omissions and deviations from standard recommendations.
Maintaining a healthy lifestyle, including a high-quality diet, moderate exercise, and low alcohol consumption, was associated with lower cardiometabolic disease risk. The study found that adhering to these healthy behaviors reduced the risk of major cardiometabolic diseases independent of medication use.
This mixed-methods cohort study reveals pervasive violence against Australian women who inject drugs, with severe consequences. Despite this, rates of seeking healthcare remain low due to structural and social barriers.
A new tool, metapipeline-DNA, automates and standardizes genome sequencing analysis, reducing the complexity of large and complicated data. The open-access resource, developed by Sanford Burnham Prebys and the University of California Los Angeles, aims to improve collaboration and reproducibility across research labs.
A new project at the University of Bonn's BCDSS Cluster of Excellence and the Department of History aims to analyze and render visible nameless individuals in historical records. This study sheds light on the identities and power dynamics of the past, particularly in the context of slavery and colonialism.
A systematic review and meta-analysis found that brief interventions after a suicide attempt can significantly reduce re-attempts. Participants who received these interventions were 28% less likely to attempt suicide again than those receiving usual medical care.
A study of nearly 700,000 health records reveals that young people with cannabis use disorder are more likely to be diagnosed with psychiatric disorders, such as schizophrenia, recurrent major depression, and anxiety disorders. In contrast, adults with cannabis use disorder are less likely to develop these conditions.
Research from Stanford University reveals that warmer, wetter weather conditions linked to climate change are making disease epidemics more likely, with a study analyzing a 2023 cyclone and dengue fever outbreak in Peru estimating that 60% of cases were directly caused by extreme rainfall and warm temperatures. Targeted mosquito contro...
Professor Iwa Salami argues that stablecoins require strong regulation to support safe growth and innovation in UK finance. The expert calls for clear legal protections, robust operational standards, and close international cooperation to mitigate risks and ensure consumer protection.
Dr. Aliesha O’Raw, Principal Investigator at TIBI and Co-Founder of OnVagus, has been selected for the 2026 ACS BrightEdge Entrepreneurs Program. The program provides mentorship, entrepreneur training, and early-stage investment support to advance cancer diagnostic and therapeutic solutions.