Researchers analyzed 17 clinical trials and found little evidence that smokers increase smoking behavior when switching to low-nicotine cigarettes. In fact, most participants smoked significantly fewer cigarettes after making the switch.
A study by Wake Forest University School of Medicine found nearly one in five caregivers reported experiencing food insecurity during their child's hospital stay. Children whose caregivers faced food insecurity stayed in the hospital about a third longer on average, with higher rates of readmission within 30 days.
A new immunotherapy combination has shown promise in delaying cancer progression and improving survival for patients with multiple myeloma. The study found that nearly nine in 10 patients receiving the treatment experienced a shrinkage of their cancer, compared to about eight in 10 on standard treatment.
Researchers developed an AI-based score from standard ECGs that reflect biological development on a spectrum rather than in fixed categories. The Electrocardiographic Sex Index (ESI) captures step-by-step changes of normal growth and hormonal changes, offering a more precise way to account for developmental stage.
Researchers found that structured lifestyle programs with coaching and accountability can reduce frailty in older adults by promoting healthy habits. The two-year US POINTER trial showed significant improvements in overall health and frailty scores among participants who followed the structured program.
Researchers at Wake Forest Institute for Regenerative Medicine have identified a unique gene pattern specific to Ebola, allowing doctors to distinguish it from other infections. This discovery has the potential to improve diagnostic tests and save lives in outbreak settings.
A large randomized trial shows that continuous wearable monitoring reduces time with dangerously low oxygen levels after surgery, leading to improved composite outcomes and safety. The study found a 30-minute reduction in hypoxemia and a significant risk reduction for desaturation events.
A large randomized trial shows measurable improvements in postoperative patients who received continuous wearable monitoring, reducing time with dangerously low oxygen levels and composite outcomes. The study found a statistically significant 14% risk reduction for dangerous desaturation events and overall safety improvement.
Researchers developed CAR macrophages that crossed the blood-brain barrier, recognizing and destroying cancer cells and releasing signals to harm nearby tumors. The treatment showed significant reductions in brain tumor progression and increased survival in preclinical models.
Researchers found that ultrasounds performed too early during hospitalization were more likely to produce false positives, leading to additional invasive testing. Waiting until a fever resolved and closer to discharge did not prolong the hospital stay, but reduced unnecessary tests and added stress for families.
A small observational study found that most women with macromastia who experienced frequent headaches screened positive for migraine rather than tension-type headache. After surgery, participants reported fewer and less severe headaches, with improvements lasting over a year.
A global study found that ropeginterferon alfa-2b controls essential thrombocythemia effectively, improves symptoms and reduces serious complications in patients who can't use hydroxyurea. The therapy is expected to be approved for treatment of high-risk blood cancer.