Researchers found that radiation-resistant cancer cells are vulnerable to NK cell-mediated killing due to increased expression of specific cellular membrane proteins, creating an 'evolutionary double-bind'. The combination of radiation therapy and NK cell-based immunotherapy was more effective in suppressing both sensitive and resistan...
A new rice gene, GSN7, has been discovered that can simultaneously increase grain yield and improve quality. The study found that precise manipulation of this gene can overcome the long-standing trade-off between yield and quality in rice breeding.
Researchers developed an AI method to predict mastoidectomy shape before surgery, enabling better navigation and visualization for surgeons. The approach achieved a high Dice score of 0.72 compared to popular medical imaging models.
Researchers developed a multilayered insulated superhydrophobic (MISH) coating that maintains repellency up to 90°C, outperforming conventional coatings. The coating's insulating layer reduces heat transfer, preventing condensation and maintaining 'never-wet' properties.
Research shows that expert birders have more compact attention- and perception-related brain areas, linked to accurate bird identification. These structural changes persist in older birders and may benefit cognition as people age.
A new study found that Black young adults experiencing high levels of online racism are more likely to use digital mental health tools. The research also showed that these individuals were more likely to engage in online mental health communication, regardless of their anxiety or depression symptoms.
Researchers at King's College London have developed highly reactive aluminium molecules that can break apart tough chemical bonds. The team discovered a new compound called cyclotrialumane, which exhibits unprecedented reactivity and retains its structure in various solutions.
Researchers found that implanted cuff electrodes can trigger unintended nerve stimulation during MRI, causing discomfort or pain. The study recommends more refined guidelines and careful safety considerations to mitigate this risk.
Scientists at the University of Chicago have created Prussian blue analogs that can achieve 99.9% lithium purification, opening up new opportunities for separating industrial waste ions from environmental streams. The unique structure of Prussian blue analogs allows for selective filtering and purification.
A new study found that almost all people with obesity (BMI ≥ 30 kg/m²) exhibit increased body fat mass and health-related complications. Clinical obesity is associated with a 3-8 times higher risk of cardiovascular disease and type 2 diabetes compared to non-obese individuals.
Researchers review schizophrenia mechanisms, including neurotransmitter dysregulation and immune dysfunction, to develop next-generation therapies. Promising treatments include TAAR1 agonists, muscarinic modulators, NMDA receptor enhancers, and probiotics targeting the gut-brain axis.
A study by St. Jude Children's Research Hospital found that radiation therapy contributes to hearing loss in children treated for brain tumors, leading to greater cognitive decline. Children with severe hearing loss experienced a more significant decline in cognitive measures compared to those without.
Researchers at IISc have mapped a neural circuit that links stress to itch. Stress activates specific neurons in the lateral hypothalamic area, which directly regulate itch and reduce scratching behavior. This study provides new insights into the complex relationship between emotional states and sensory perception.
Tumor-infiltrating lymphocytes (TIL) therapy is a form of immunotherapy that harnesses the body's natural defenses to fight cancer. Researchers at Ochsner MD Anderson have successfully treated advanced melanoma using this innovative approach, with many patients experiencing tumor shrinkage or elimination after treatment.
A new study analyzing global Google Trends data reveals a sharp increase in online searches for crisis hotlines, particularly in recent years. The findings suggest that digital help-seeking signals can provide timely insight into population distress and demand for crisis resources.
A new study published in Acta Psychiatrica Scandinavica found that people with mental illness who use AI chatbots risk experiencing a worsening of their condition, particularly in terms of delusions and mania. Researchers are calling for increased awareness among healthcare professionals about the potential risks of AI chatbot use.
The Norwegian University of Life Sciences has launched ClimateDataForBuildings, an open platform providing energy and climate modelling data for over 3,600 European locations. The platform delivers high-resolution CERRA reanalysis data for building performance and HVAC design.
Researchers at the University of Waterloo have discovered a way to convert microplastic waste into acetic acid, the main ingredient of vinegar, using sunlight. The breakthrough offers a promising new approach to reducing plastic pollution through photocatalysis, creating a valuable chemical product.
A new study by SMART has identified a strong statistical association between global air connectivity and patterns of multinational corporations' investments. The research found that few layovers meant more subsidiaries, with cities having better flight connections to influential hubs outperforming those with less-connected destinations.
Researchers found that silencing bacteria can worsen heart infections by promoting aggressive biofilm growth and reducing antibiotic effectiveness. The study highlights the need for targeted therapeutic strategies against infectious endocarditis.
Researchers developed an AI approach to visualize subtle tissue changes in the pancreas for type 2 diabetes. The study created an extensive data set and trained deep learning models that accurately predicted diabetes status and identified potential biomarkers.
Astronomers have found that the fundamental physical processes generating auroras are common to different celestial bodies, including the largest moon in the solar system. Observations of Ganymede's auroras reveal locally fragmented patches similar to those on Earth and Jupiter, suggesting a universal mechanism for aurora formation.
Researchers developed a technology that precisely controls the internal structure of semiconductors using heat, enabling faster AI computations with reduced electricity. The approach improves the performance of next-generation artificial intelligence hardware.
Researchers at the University of Oulu have developed new bio-based resins that match or exceed the performance of fossil-based counterparts. The resins are produced from biomass-derived platform chemicals and offer a critical sustainability advantage: chemical recyclability.
NUS food scientists develop a healthier, tastier kombu by co-fermenting enzyme-treated kombu with lactic acid bacteria and aroma-producing yeast. The resulting probiotic blend promotes nutrient bioaccessibility and introduces fruity aromas.
Researchers at the University of Basel have unlocked the magnetic properties of individual bacteria, enabling them to navigate using an Earth-based compass. This discovery holds promise for medical applications, such as magnetically controllable microrobots, and environmental research.
Research at University of Eastern Finland found that positively charged polystyrene nanoparticles increase early embryo mortality in European whitefish under stressed conditions. The study suggests that surface charge plays a critical role in toxicity assessment, with negatively charged particles experiencing reduced harmful effects.
Researchers from the University of Ottawa have developed a groundbreaking biomaterial that combines strength, adaptability, and biological compatibility for soft tissue repair. The hydrogel is made from synthetic peptides and can be precisely tailored through chemical design, making it an attractive alternative to existing biomaterials.
Researchers at the Max Planck Institute for Brain Research discovered that stressed animal cells, including neurons, assemble inactive ribosomes into tightly linked pairs, known as disomes. This novel mechanism relies on a specific piece of ribosomal RNA called an expansion segment to form a precise RNA-RNA interaction.
The team will use SPARK THE MIDLANDS programme to advance healthcare research and develop a minimally invasive cancer-killing paste. The paste, made from gallium-doped bioglass, has shown a 99% success rate of eliminating cancerous cells and regenerating diseased bones.
Researchers discovered that adding salt additives and water enables PEDOT:PSS to grow hair-like fibers conducting electricity. The material's stretchability and conductivity can be enhanced by adjusting the chemical makeup, making it suitable for bioelectronic devices.
Researchers at Linköping University have developed an AI-boosted electronic nose that can detect ovarian cancer from blood plasma samples with high accuracy. The method uses machine learning to identify patterns specific to the disease, making it a promising tool for early detection and improved survival rates.
Researchers have observed a new microscopic mechanism enabling precise control of magneto-optical properties in alloys of two-dimensional semiconductors. The discovery opens up prospects for technological applications in devices exploiting valleytronics.
Researchers developed a new imaging technique using shortwave infrared imaging to visualize injectable filler materials during laryngoplasty, improving treatment accuracy and confirming correct placement. The technique has potential applications in identifying vocal fold pathologies and differentiating tissue layers.
The collaboration will utilize Mayo Clinic Platform's secure infrastructure to analyze de-identified patient data from both institutions, enhancing research and driving innovation in healthcare. With access to over 15 million patients, the partnership aims to predict illness earlier, improve outcomes, and deliver more proactive care.
The University of Cincinnati's new UC/UC Health Addiction Center aims to improve addiction prevention and treatment outcomes through innovative research, enhanced clinical services, and education excellence. The center will coordinate activities across five UC colleges and 12 departments to foster interdisciplinary solutions.
Researchers found that male patients with early Lyme disease present with different signs of the disease, including symptoms, physical exams, and laboratory test results. These findings suggest that sex and menopause status are important to consider in understanding early Lyme disease.
Researchers at Colorado State University have found a way to boost plant growth while maintaining its immune system through hormone treatment, showing promise for increasing food production. The approach involves genetically manipulating phytohormone interactions to restore cell division and increase disease resistance.
Horses produce high-frequency sounds by whistling through their larynx while vibrating vocal folds. Researchers found that the high-frequency component of the whinny is generated by a laryngeal whistle, shifting to higher frequencies when helium is used.
A study from Rutgers University suggests that exposure to alcohol in social media drives the desire to drink. Young adults who viewed influencer posts with alcohol were significantly more likely to report increased desire to drink compared to those who watched similar posts without alcohol.
Exposure to alcohol-related social media content is associated with increased desire to drink among young adults, regardless of prior alcohol use. Social media influencers may contribute to normalization of alcohol consumption among this age group.
The study found that increased community disadvantage leads to fewer options for receiving hemodialysis and more likelihood of living without nearby dialysis facilities. Patients with end-stage kidney disease in these areas have limited access to essential care services.
Astronomers have imaged and modeled an exceptionally rare supernova that could provide a new way to measure the universe's expansion rate. The supernova, known as SN Winny, is a superluminous stellar explosion 10 billion light-years away and appears five times in the night sky due to gravitational lensing.
A new study found that US newborn hepatitis B virus vaccination rates declined by over 10 percentage points in the last 2 years. This decline reverses 6 years of growth and is aligned with WHO and CDC coverage estimates through 2022.
Researchers found that certain inhalers used to treat chronic obstructive pulmonary disease (COPD) are not only less harmful to the environment but can also lead to slightly better patient outcomes. The dry powder inhaler was associated with a 14% lower risk of moderate or severe COPD exacerbations compared to metered-dose inhalers.
A study published in JAMA Neurology found that adhering to healthy dietary patterns, such as the DASH diet, is associated with lower subjective cognitive decline and better cognitive function. The findings highlight the importance of a balanced diet for maintaining long-term brain health.
Researchers are developing an organ-on-a-chip platform to study immune rejection in pig-to-human liver transplantation, addressing a major hurdle in xenotransplantation. The project aims to generate data supporting future preclinical studies and bring xenotransplantation closer to clinical use.
Southwest Research Institute expands manufacturing capabilities to produce safer antidotes to organophosphorus nerve agents and pesticides. The new technique avoids cancer-causing compounds during synthesis of oxime antidotes, supporting kilogram-scale manufacturing for domestic supply and reducing supply chain risks.
A high-fiber diet has been linked to a reduced risk of coronary artery disease in night shift workers. The study, published in the European Journal of Epidemiology, found that consuming more fiber daily can lower the risk, with moderate intake recommended for those working night shifts regularly.
A Canada-wide study using DNA metabarcoding reveals the intricate relationships between cavity-nesting bees and wasps and their food sources. The project, involving over 5000 students, creates detailed maps of these interactions, providing valuable insights into biodiversity and conservation.
A fully integrated robotic platform automates sample identification, loading, measurement, and consumables replacement to significantly shorten catalyst development timelines. The system reduces variability in experimental results by 32% and completes a manual process of 32 days in approximately 17 hours.
A new study found that the US EPA's criminal prosecutions for environmental crimes correlate strongly with a county's socioeconomic status, rather than its level of pollution. Wealthier counties receive 24% more enforcement actions on average, while poorer counties are less likely to be targeted.
A team of researchers applied adaptive-bandwidth kernel density estimation to analyze the latest reversal timing dataset, revealing four distinct dips in the new reversal frequency model following the Cretaceous Normal Superchron. This suggests that short-time-interval geomagnetic reversals may be missing from the compiled record.
The University of Miami business technology department has earned the top research productivity ranking in information systems, driven by exceptional faculty and research performance. The department's No. 1 national ranking reflects its sustained research productivity across top scholarly journals.
Research by the American Psychological Association finds that eponymous laws, those named for victims of tragedy, surge in public support due to sympathy and emotional connection. However, this boost may come at the expense of effective policymaking.
CERCat research projects combine physics-based and AI-based models to predict extreme weather hazards, assess vulnerability, and predict regional climate impacts. The partnership enables the development of machine learning systems for real-time damage assessments and multi-scale hazard modeling.
Researchers at the University of Colorado Boulder have developed high-performing optical microresonators that can trap light and build up its intensity. By guiding light smoothly through the resonator, they dramatically reduced light loss, allowing photons to circulate longer and interact more strongly inside the device.
A new poll finds that pets contribute to healthy aging benefits for older adults, including increased sense of purpose and reduced stress. However, 31% of pet owners aged 50+ report that owning a pet strains their budget, mainly due to financial costs.
Engineers have refined a technology to edit individual genetic base pairs, reducing unintended edits and increasing safety for potential treatments. The new base editors could lead to better outcomes for some cystic fibrosis patients and more accurate models for drug testing.
Co-infection of Cryptococcus neoformans and Mycobacterium tuberculosis increases risk of death significantly compared to fungal infection alone. The fungus changes its cell density, diversity, and capsule size in response to the bacterial pathogen.