A $3.1 million R01 grant will fund research exploring how targeted therapy can strengthen bones in children with osteogenesis imperfecta while still in the womb. The goal is to develop a prenatal drug therapy that improves outcomes for both mothers and children.
Internationally recognized pediatric hand surgeon Dr. Scott H. Kozin takes the helm as Shriners Children's Chief Medical Officer, bringing decades of clinical expertise to expand access to high-quality pediatric care nationwide. The appointment comes at a pivotal moment, with the upcoming opening of the new Shriners Children's Research...
A multi-center study by Shriners Children's aims to demonstrate the effectiveness of fractional CO2 lasers in treating pediatric burns, potentially leading to changes in insurance coverage. The two-year study will provide data on improved patient outcomes, including reduced scarring and increased mobility.
Researchers have developed circadian-based gene circuits that align with the body's natural rhythm, delivering anti-inflammatory drugs on a daily basis. The technology has the potential to reduce symptoms and prevent joint damage, potentially changing the course of the disease.
Babies and children are more susceptible to frostbite due to faster heat loss and impaired judgment from extreme cold. Shriners Children's Boston advises taking breaks every 15 minutes to prevent frostbite in children and teens.
Researchers developed gene therapy that automatically converts harmful Omega-6 fatty acids to beneficial Omega-3s, reducing risk of arthritis and other health problems in children with obesity. The treatment also lowered inflammation and improved metabolic health.
A new study by Shriners Hospitals for Children finds that biochemical signals released by fat cells are responsible for osteoarthritis. The investigation, led by Dr. Farshid Guilak, suggests a factor given off by fat cells makes cartilage susceptible to degeneration.