Researchers at the University at Buffalo have successfully grown salivary glands from human pluripotent stem cells, offering a promising solution for patients with dry mouth due to cancer treatment or Sjögren’s disease. The newly formed glands integrated with existing tissue and contained mature cells that produce saliva, suggesting po...
A study published in the journal Psychedelics found that 18 of 19 tips from an obscure 1967 guide for LSD use were agreed upon by survey participants, emphasizing the importance of interpersonal trust, personal responsibility, and psychological preparation for safe and meaningful psychedelic experiences. The study highlights the releva...
Researchers found a mathematical solution describing how a spin glass transitions to ultrafast behavior resembling a black hole. The discovery connects ultraslow quantum magnetism to fast, entangled dynamics, with potential applications in quantum technologies.
A recent study found that one-third of older adults with cognitive disorders are taking prescription drugs that could harm them, increasing risk of premature death and poor mental health. However, exposure to these drugs decreased significantly between 2011 and 2022, with a 11-year decline in inappropriate medication use
A newly developed drug molecule binds to its target protein by causing it to change shape, creating an unusually snug fit. The molecule's unusual binding strategy offers a new approach to drug design and may provide a starting point for developing a new cancer treatment.
AUB investigator Amanda Ziegler aims to make healthy lifestyle changes accessible for teens to address obesity and cardiometabolic diseases. The PrevenTeen project utilizes AI-powered mobile health tools to develop pragmatic approaches for adolescent patients.
UB's summerMAXyc program improved social skills, behaviors, and autism symptoms in autistic children ages 4-6. The 5-week program, conducted five days a week, followed a similar model to the IAR's successful summerMAX program for older children.
Researchers will develop AI-powered tools to examine cascading wildfire impacts, including flash floods, debris flows, and infrastructure disruptions. The project aims to bolster public safety and community resilience by combining AI, infrastructure modeling, and social science.
A new study led by the University at Buffalo sheds light on RNA's ability to form droplets, which may have helped give rise to the first cells. The study found that a tiny chemical difference between RNA and DNA enables RNA to more readily organize into droplets, particularly at high temperatures.
Brown tree snakes have more genetic diversity than initially thought, thanks to advanced sequencing technology that revealed thousands of structural variants. This unexpected diversity may help explain how the invasive species thrived despite a severe genetic bottleneck.
A University at Buffalo study has identified a link between Canadian wildfire smoke and decreased bird sightings in New York State. Analyzing air quality data with birdwatching reports, researchers found that nearly half of the studied species were less likely to be observed when PM2.5 levels rose, including many migratory forest songb...
Researchers developed a new method using blue LED lights and commercial chemical building blocks to modify two carbon atoms in a single reaction, increasing the complexity of molecules quickly. This approach could lead to faster production of complex drugs with specific properties.
Researchers used structured light from quantum optics to transform Boehm's brushes into brighter patterns, improving their detectability. This technique may help diagnose retinal diseases like macular degeneration.
A University at Buffalo-led team has developed a method to reliably measure cortical lesions in MS using artificial intelligence. By analyzing existing MRI scans, they found over 11,000 cortical lesions, revealing new insights into the disease's progression and cognitive impairment.
A University at Buffalo study covering 40 years of data found that family-based behavioral treatment can prevent children from developing metabolic disease as adults. The treatment resulted in long-term improvements in health and reversed obesity status in nearly half of the participants.
Researchers propose a new way to detect altermagnets, a recently discovered class of magnetic materials that could revolutionize information transport and storage. The quantum sensor would measure the relaxation of a tiny magnetic defect in a diamond to identify altermagnetism.
Researchers have discovered ancient iceberg plowmarks along the Great Lakes that suggest lake-effect snow was pushed toward western shores during the Ice Age, potentially reducing snowfall in cities like Buffalo and Cleveland. The study provides critical context for paleoclimate researchers studying future climate patterns.
A new study found that natural selection favored Indigenous Andeans with high numbers of salivary amylase genes, leading to a higher frequency of these genes in the population. This suggests that potatoes played a crucial role in shaping the genetic makeup of this population.
A UB-led team has found a way to help chiral semiconductors, electronic materials whose structures are left- or right-handed like many of life's building blocks, absorb visible light. Researchers chemically combined a chiral semiconducting material with a non-chiral molecule that more readily absorbs visible light.
A study at University at Buffalo found that L-arginine enhances protein droplet stability, preventing fibril conversion and preserving microtubule assembly. This naturally occurring small molecule may help guide therapies targeting fibril formation in Alzheimer's disease.
A recent JAMA paper identifies key symptoms and signs that strongly indicate a child has sustained a concussion. Common symptoms include headache, dizziness, mental fog, nausea, sensitivity to light and noise, and difficulty remembering.
A new study by the University at Buffalo reveals that unequal access to recycling facilities plays a key role in shaping plastic waste management practices in the US. Wealthier and more college-educated communities are more likely to have convenient access to large-scale industrial recycling facilities, making recycling easier and more...
A study published in Cell Chemical Biology reveals that an impaired transport protein and ceramide buildup can trigger replicative senescence, a state where cells remain alive but no longer divide. Ceramides accumulate inside the endoplasmic reticulum, triggering stress signals that lead to cellular limbo.
Researchers created a new method combining scientific tests and artificial intelligence to differentiate recycled plastic from new plastic. The tool, developed by University at Buffalo researchers, can analyze samples and predict the percentage of recycled content with over 97% accuracy.
Researchers report a significant association between muscle strength and lower mortality risk in women aged 63-99 years. Grip strength and chair stands were found to be key indicators of muscular strength, with even small improvements leading to notable reductions in death risk.
Researchers at the University at Buffalo have developed a new inhalable form of tuberculosis (TB) treatment that delivers rifampin directly to the lungs, reducing liver damage and improving immune activity. The study found that inhaled nanoparticle treatment kept higher levels of the drug in the lungs for up to a week after a single dose.
Researchers found that altering how alpha-synuclein interacts with LRRK2 limits its ability to bind to cargo and disrupt axonal transport. This suggests a functional link between the two proteins, which may help understand the triggers of Parkinson's disease.
A survey of 438 adults who used cannabis in the past year found that nearly 56% also drank alcoholic beverages, with users more likely to substitute cannabis for alcohol. Respondents reported consuming fewer alcoholic drinks and binge drinking less frequently after starting cannabis beverages.
Researchers found that photons and atoms don't always rapidly reach thermal equilibrium as expected. Instead, they can settle at different temperatures for extended periods, allowing for the preservation of quantum behavior. This prethermal state can last long enough to matter for neutral-atom quantum computers.
A recent study from the University at Buffalo has found that cigarette filters release up to two dozen microfibers upon first contact with water, posing a significant threat to wildlife and human health. The researchers estimated that over 71 million to 1.4 billion cigarette butt microfibers are released into New York waters every day.
Two studies by the University at Buffalo found that harm reduction vending machines are well utilized and provide critical services to high-risk individuals. The machines dispense supplies such as naloxone kits, fentanyl test strip packages, and xylazine test strips outside of regular business hours.
A new study from GreenDrill reveals that the Prudhoe Dome ice cap melted approximately 7,000 years ago due to mild Holocene-era temperatures. This finding highlights the region's vulnerability to human-induced climate change and has significant implications for sea level rise predictions.
Experimental evidence confirms that a single superconductor can induce electron pairing and synchronization in another material, enabling the creation of a Josephson junction with only one superconductor. This discovery has potential implications for topological superconductors and conventional quantum computers.
A University at Buffalo researcher has developed a framework to help scientists incorporate community input into Earth system models, providing more accurate and relevant regional climate data. The framework outlines four levels of co-design, allowing modelers to incorporate local knowledge and observations directly into the model.
A new study by the University at Buffalo found that 12th graders who use two or more cannabis products are more likely to engage in binge drinking. The study suggests that certain modes of cannabis consumption, such as smoking and vaping, may be linked to higher risks of binge drinking.
A genetic variant is likely putting some children with myocarditis at higher risk of developing heart failure. The study found that 34.4% of children with dilated cardiomyopathy had a genetic variant, compared to only 6.3% of control children.
A randomized, controlled pilot study found that preloading Instacart online grocery carts with healthy ingredients resulted in families making significantly more nutritious purchases compared to a group receiving only recipes. Families made healthier choices easier and more automatic.
Researchers found that linear isomers of PFOS accumulate more in fish-eating birds and tissue, whereas branched isomers dominate wastewater and benthic fish. This suggests that consumers eating bottom-dwelling species may be exposed to higher levels of PFAS.
A study at the University of Buffalo discovered a new membrane that separates hydrogen from CO2 with a record-breaking selectivity of 1,800, outperforming previous rates by 18 times. The crosslinked polyamines-based membrane also exhibits self-healing properties and stability under extreme conditions.
Physicists at University at Buffalo have developed a user-friendly template for simulating quantum systems on consumer laptops. The new method, based on the truncated Wigner approximation, allows for efficient simulations of dissipative spin dynamics in hours, saving supercomputers for complex problems.
A study by University at Buffalo researchers reveals that some elements' semicore electrons can participate in bonding under just a few gigapascals of pressure, far lower than previously thought. This finding challenges traditional notions of core electron behavior and may have implications for our understanding of planetary evolution.
University at Buffalo researchers capture high-resolution image of stable, open NMDA receptor, revealing kinked helices that stabilize the pore. The study expands understanding of receptor function and malfunction contributing to neurodegenerative diseases.
Research finds fish diversity declining in arid regions of US and Australia due to reduced water availability. Climate change is also affecting these ecosystems, but the study's findings suggest multiple stressors are at play.
A new study reveals that small electric charges between particles play a crucial role in forming highly concentrated clusters in turbulent environments. This discovery has significant implications for climate research, medicine, engineering, and science, enabling better predictions and controls.
A new study published in PLOS One finds that high-intensity interval training (HIIT) is more effective than moderate exercise in making adolescent lab animals avoid cocaine. The researchers observed a dose-dependent effect on the brain's reward circuit, leading to increased aversion to the drug.
Oral mucositis increases infection risks in stem cell transplant patients by nearly four times, according to new research. A superior AI tool has been introduced to accurately predict these risks, enabling targeted oral care before transplants and reducing complications.
Researchers have developed a new method to accurately measure the acidity of PFAS, finding some to be thousands of times more acidic than previously thought. This breakthrough could help track the persistence and spread of these toxic chemicals in the environment.
Researchers found that a faster rate of binding does not always translate to greater potency, as the study's lead author David Heppner explained. The team proposed a two-step design process balancing inactivation efficiency rates with target selectivity and other parameters to identify promising compounds.
Researchers created a glycan-binding protein that can analyze and treat diseases via sugar patterns found on the surface of cells. The tool, named sCore2, was developed by retraining an enzyme to bind to specific sugars, providing a new way to study glycans and their role in disease.
Researchers from University at Buffalo and University of Colorado Boulder have developed novel equations to characterize two-dimensional wave patterns, including the 'matrix tide' observed in China's Qiantang River. These equations use numerical simulations to model complex wave patterns that were previously difficult to solve.