Researchers developed an oxygen-modified sulfide electrolyte that stabilizes interfaces while maintaining rapid lithium transport, leading to high-performance solid-state batteries. The approach improved battery stability, capacity, and cycling life, opening opportunities for safer and faster-charging solid-state batteries.
Researchers directly observed Meissner effect in 2D van der Waals superconductors, providing evidence of superconductivity in low-dimensional systems. The study used a new high-sensitivity method to detect magnetic signals in ultrathin samples.
Research reveals bacteria rely on circadian clocks to organize colonies, controlling gene expression and pattern formation. The discovery has important implications for understanding bacterial ecology and improving plant growth.
A team of researchers has found that the energy of light used to excite spin defects in hexagonal boron nitride affects their performance, leading to a threefold boost in contrast and calculated DC magnetic field sensitivity. The study also reveals a trade-off between emission stability and signal strength.
A new peptide agonist, beta01, has been designed to target the kappa opioid receptor with high efficacy and reduced β-arrestin signaling, offering improved safety profiles for chronic pain and pruritus treatment. The study demonstrates a structure-based rational design approach for biased KOR agonists.
Researchers at HKUST have developed a novel GenAI framework called Decoupled Generation and Registration (DGR) that can produce high-fidelity virtually stained images even when training image pairs are imperfectly aligned. DGR demonstrated stronger overall performance in image quality and structural fidelity across multiple tasks compa...
Researchers at Flinders University have found evidence of 7000 years of Aboriginal mining at Sugarloaf Hill in South Australia's Riverland region. The study sheds light on the traditional practices and trade networks of Aboriginal people in the area.
Researchers found that consuming vitamin K1-rich foods like leafy greens reduces the risk of chronic obstructive pulmonary disease (COPD) by 16%. Vitamin K1 may activate a protein protecting lung tissue, while fibre and antioxidants in greens boost its effect.
A new study reports a residue-free electrolyte additive, sodium trifluoromethanesulfinate (NaSO₂CF₃), designed to improve initial efficiency, cycle life, and manufacturability in sodium-ion batteries. The additive improved Coulombic efficiency from 82.6% to 96.0% and maintained capacity retention after 600 cycles.
A new study by Flinders University researchers has identified key research priorities to enhance recognition and support for unpaid carers in Australia. The priorities include recognition, early identification, timely access to services, and post-care support, as well as carer self-care and wellbeing.
Researchers developed a synergistic strategy using glutathione additives to improve the efficiency and stability of inverted perovskite solar cells. The approach enhances charge transport, reduces energy loss, and strengthens structural stability, resulting in high power conversion efficiency and operational stability.
The study introduces a phenotype-aware contrastive learning framework that leverages self-supervised learning on large-scale sequence datasets. BCRInsight accurately deconvolves B-cell subset compositions from bulk BCR-seq data, achieving an AUROC of 0.962 in antibody paratope prediction.
A new multimodal neural network model, MM-LHRNet, enhances atmospheric CO2 retrieval using laser heterodyne radiometry by doubling accuracy while tripling speed. The model achieves a retrieval standard deviation of 0.49 ppm and precision of 0.11%, outperforming traditional methods.
A team of scientists developed a minimalist optical system for achromatic imaging based on a monolithic integrated meta-axicon cluster. The novel imaging paradigm combines natural wideband consistency and computational imaging technology to achieve large-aperture, wide field of view (FOV), broadband achromaticity, and high resolution.
Researchers analyzed 32 years of global observations to identify eight daily patterns of aerosol optical depth (AOD) variability. These patterns are linked to land surface conditions and aerosol types, suggesting local environments play a significant role in shaping AOD behavior.
New research reveals extreme heatwaves accelerate ozone and secondary organic aerosol formation through a synergy between plant-released chemicals and soil nitrogen emissions. This natural feedback loop can offset decades of anthropogenic pollution control, posing significant challenges for air quality management.
Researchers have designed a material with an exceptionally broad zero-thermal-expansion temperature window, enabling stable performance in extreme temperatures. The novel crystal structure enhances flexibility and preserves negative thermal expansion at high temperatures.
A study by Osaka Metropolitan University found that Japan's Location Optimization Plan can lead to higher care burdens in small municipalities. Small cities with populations under 50,000 saw increased Long-Term Care Insurance certification counts after adopting the policy, indicating rising service demands.
Researchers developed a pH-triggered nanocomposite that synchronizes the release of therapeutic agents, combating bacterial biofilms and oxidative stress. The platform accelerates healing and promotes tissue repair in infected wounds.
Amelie G. Ramirez is studying the impact of therapeutic yoga on health-related quality of life, fatigue and physical function in Hispanic breast cancer survivors. She aims to find culturally responsive ways to support recovery through a comparison of standard physical therapy and therapeutic yoga.
Climate conditions are increasingly limiting direct air free cooling in data centers, particularly across the tropics and southeastern US. Projections indicate continued expansion of these constraints with sustained warming and increasing humidity.
Researchers investigated phosphate double-bond character in solid and liquid phases using oxygen K-edge X-ray absorption spectroscopy. The study found that the double-bond character increased with increasing negative charge in the solid phase, but decreased in aqueous solutions due to interactions between phosphates and Na+ ions.
Carbon quantum dots can be designed to absorb specific wavelengths using atomic defects, enabling targeted optical functions and applications. The study provides a predictive framework for designing defect-encoded CQDs with controlled excitonic behavior.
Researchers found that field-based homeless healthcare programs can improve the management of high blood pressure among homeless individuals, leading to a significant reduction in mortality and disability. The study suggests that these programs can have a positive impact on the health of people experiencing homelessness.
The new calculator predicts that over 98% of people eligible for statin treatment are at low risk of serious muscle disorders. The tool aims to support informed treatment decisions by providing personalized risk estimates, helping patients and clinicians weigh benefits and risks.
A growing DRC Ebola outbreak has confirmed transmission in Uganda, and experts estimate a 70% chance of it spreading to South Sudan. The virus is potentially on course to reach South Sudan due to busy border crossings.
Researchers have developed a dual-targeting strategy to combat emerging infectious diseases. A fully human monoclonal antibody cocktail provides complete protection against lethal Nipah virus infection, even when treatment is given after infection has begun.
Researchers at the University of Washington created PaperTok, a tool that uses AI to help scientists and researchers create short-form videos from research papers. The system generates scripts and video clips in 45 seconds, making it easier for non-experts to engage with scientific content.
Researchers developed a two-page decision aid to help patients weigh options between daily pill and injectable PrEP treatments without feeling judged. The tool targets an awareness gap in PrEP usage, with only 36% of eligible Americans taking the treatment.
A UK study found that people most in danger from heat have the least access to air conditioning, with homes with older residents and single parent families using it the least. The research highlights a 'cooling divide' where those who need protection from heat are least able to get it.
A new study by Northwestern Medicine found that patients with severe injuries from car crashes are 70% less likely to be transferred to another hospital in states with no-fault insurance laws. This is because policies guarantee reimbursement for trauma care, incentivizing hospitals to keep and treat seriously injured patients.
Researchers found that patients who received tranexamic acid during liver surgery were three times less likely to develop post-hepatectomy liver failure than those who received a placebo. The study suggests targeting the body's fibrinolytic system may support liver regeneration and reduce liver failure risk.
The EU project BRISA aims to test safe and clean industrial technologies that reduce risks to human health and biodiversity. The project will protect over 45,000 workers by 2035 and prevent hundreds of premature deaths each year.
Glenn Thackray takes the helm as GSA President, focusing on advancing geoscience research, education, and public service. With a strong background in leadership experience and passion for mentoring the next generation of scientists, Thackray aims to strengthen the Society's impact.
The Center for Advanced Turbomachinery and Energy Research (CATER) is expanding its mission and reach as an official university center. CATER will focus on areas like hypersonics, national security, energy and sustainability, advanced air mobility, and space power and propulsion.
Salk Institute researchers discovered chronoferroptosis, a chronic stress pathway in cells that causes neurons to become less resilient over time and more susceptible to neurodegeneration. Iron accumulation was found to lower the cells' defenses, making them more vulnerable to stressors.
A new study challenges the common notion that sports are inherently good and finds a link between heavy-contact youth sports participation and acts of violence. Dropping out of organized youth sports is particularly associated with committing acts of violence over the life course.
Researchers at Texas A&M University develop a laser technique called TRIP to directly measure quantum forces shaping proteins, enabling accurate prediction of how pharmaceutical drugs interact with them. This breakthrough could lead to the design of medicines tailored to specific diseases, revolutionizing precision medicine.
Researchers at UT Health San Antonio found a link between the bacterium Faecalibacterium prausnitzii and systemic lupus erythematosus. Supplementation with this bacteria reduced markers of the disease in animal models, showing promise for treatment.
Scientists have found that 15 million years ago, the Atlantic Ocean had large low-oxygen zones, while the Pacific Ocean's zones were much smaller. A new study suggests that ocean circulation and continental position played a crucial role in shaping these zones, indicating that warming alone cannot explain changes in oxygen levels.
Researchers analyzed 11.6 million marketplace interactions and experiments involving job candidates and service providers to find that faster responders were viewed more positively than delayed responders. Employers preferred speed as a signal of future responsiveness, but authenticity also mattered.
Lili Yang and her team aim to develop a universal CAR-NKT cell immunotherapy for multiple sclerosis, providing a sustained therapeutic effect that daily or weekly medications cannot match. The approach targets the core biological mechanisms of MS, offering a potentially more significant delay or even cure.
Researchers found that the Andes of west-central Argentina formed in four distinct and rapid pulses of activity, each lasting about 5 to 8 million years. This growth rate is faster and more punctuated than previously thought, outpacing the steady timeline expected from subduction.
A new study finds that climate change can impact flu season timing and severity across North, Central, and South America. Weather conditions like temperature and humidity help predict outbreaks, with tropical regions potentially experiencing stronger outbreaks while places with distinct seasons see smaller ones.
Researchers at UCLA Health Jonsson Comprehensive Cancer Center receive $1.7M grant to advance CAR T-cell therapies for metastatic castration-resistant prostate cancer. They will investigate a new approach combining engineered nanovial technology with single-cell analysis to rapidly evaluate and optimize dual-targeted CAR T-cell therapies.
American Academy of Neurology appoints A. Gordon Smith as the fifth editor-in-chief of Continuum, a leading continuing medical education journal in neurology. Smith aims to ensure educational innovation and make Continuum an essential resource for the entire neurology care community.
Roschli's research applies large-format additive manufacturing (LFAM) to nuclear energy construction, reducing production times from weeks to days. He was recognized by the American Society of Mechanical Engineers (ASME) for his contributions to additive manufacturing innovations.
A study of 193 countries finds that armed conflict leads to more measles cases, even a year after fighting ends. Socioeconomic decline is the strongest connection between conflict and measles, as it erodes health foundations and population vulnerability.
Researchers found AI can accurately assess complex quality measures in seconds, providing near real-time feedback to physicians. This results in improved compliance with national sepsis quality measures and lower administrative costs.
Research from the University of Texas at Austin finds that foreign investment drove up US housing costs, outpacing supply growth. Cities with lax regulations on foreign investors saw prices rise more quickly than in areas with stricter controls.
A University at Buffalo study covering 40 years of data found that family-based behavioral treatment can prevent children from developing metabolic disease as adults. The treatment resulted in long-term improvements in health and reversed obesity status in nearly half of the participants.
Researchers found that a 12-week lifestyle program combining exercise guidance, dietary counseling, and daily yogurt consumption significantly slowed DunedinPACE, an epigenetic measure of biological aging. The intervention resulted in a modest but statistically significant slowing of the pace of aging, corresponding to a 2.2% reduction.
Colorado State University researchers propose strategies to immobilize toxic metals and prevent plant uptake in rice grains, protecting food security and public health. The approach aims to reduce arsenic, cadmium, and mercury contamination in rice paddies using nanomaterials and chemical reactions.
The EU has adopted a new regulation allowing for simplified rules on new genomic techniques (NGTs) for plants. Researchers will face fewer hurdles to conduct field trials and develop more robust crops.
The U-M-led QuPID project aims to design connectable quantum photonic chips for field-ready, lab-grade measurements. The team plans to miniaturize these technologies with a suite of quantum components, envisioned as 'Legos' to be combined for building different devices.
A University of Arizona research team has developed a nanotechnology-based platform combining paclitaxel with siRNA to enhance the immune response against lung cancer. The approach exploits an 'eat me' signal on dying cancer cells, attracting immune cells and initiating tumor death.
A study applies machine learning techniques to analyze 3D patterns of dental enamel wear generated during food chewing, allowing for the reconstruction of ancient diets. The research identifies key variables informative for classifying dental microwear and proposes an analytical framework open to the scientific community.
A new European alliance aims to build a continent-wide system using genomics for protecting biodiversity, combining DNA barcoding and genome sequencing. The initiative will enable efficient collaboration and interoperability in biodiversity research.
A new approach for treating wounds involves delivering hydrogen sulfide directly to the wound site using a bandage-like device. This localized delivery aims to improve circulation, promoting oxygen and nutrient-rich blood flow to damaged tissue. The research team is exploring how this approach can work alongside current standards of ca...
Researchers found that crushed concrete reacts with strontium-90 to form stable calcite mineral structures, removing up to 98% of the contaminant from solution. Phosphate treatments also significantly enhance strontium retention, particularly in air-limited environments.
A new genomic study of Philodendron reveals how repeated hybridization shaped its diversity and influenced leaf color traits. The researchers assembled a high-quality genome of P. tatei and analyzed cultivars to identify key regulatory genes, including PtSGR1, which plays a crucial role in chlorophyll degradation.
The study successfully integrates probabilistic sampling and deterministic computation in generative AI hardware within a single ferroelectric memory array. The technology enables the generation of diverse images reflecting facial attributes, improving area and power efficiency in applications.
A Michigan State University researcher has challenged a long-held belief about how the liver repairs itself after surgery. By studying mice, the team found that reducing plasminogen levels led to stronger liver regeneration and improved outcomes for patients undergoing liver surgery.
The University of North Florida Institute of Environmental Research and Education is assessing the impact of road-stream crossings on river systems. The project aims to improve aquatic connectivity and strengthen coastal resilience, providing valuable insights for regional planning and flood hazard reduction.
The ESA Annual Meeting 2026 features presentations on AI in ecology for analyzing large datasets, predicting invasive species spread, and improving food security monitoring. The meeting aims to accelerate discovery and effective application of AI tools in ecological research and conservation.
Researchers developed a new system called Murakkab to optimize agentic workflows for AI applications. It enables developers to describe their intent in high-level terms, automating the selection of models and tools to use, and optimizing hardware configurations in real-time.
Researchers discovered a molecular seesaw that regulates healthy skin development. Modulating this balance with topical drugs could aid wound healing and slow skin cancer growth. The study found ubiquitin-like proteins trigger progenitor cells to mature or self-renew, leading to changes in immune cell populations.
Researchers developed light-transmitting hydrogel fibers to detect early breast cancer in narrow ducts. The soft fibers guide visible and near-infrared light with low optical loss, retaining optical properties over time.
A new UNC study explores how social media can address youth loneliness. Peer-driven social media content, featuring relatable individuals, was found to be more effective at encouraging participants to seek in-person social interaction than control content.
Researchers found a correlation between cognitive decline in geriatric dogs and reduced thoracic limb stride length, with higher Canine Dementia Scale scores associated with decreased stride length. This study provides valuable insights into the relationship between gait patterns and canine cognition.
A new drug candidate, IHMT-15137, has been discovered to target key proteins involved in chemotherapy resistance. The compound blocks BMX activity, disrupting downstream signals and reducing E2F1 levels, making cancer cells more sensitive to treatment.
Researchers have identified a potential pathway for the coordinated cell death of harmful algae, driven by iron-catalyzed lipid peroxidation. This process not only kills individual algal cells but also releases active lipid peroxides that kill off neighboring cells, leading to the rapid collapse of an entire bloom.
A modelling study across 193 countries found armed conflict is associated with a higher measles burden. The study also suggests that conflict has an indirect impact on the spread of measles through its effects on lower socioeconomic development and greater population displacement.
A study at Baystate Medical Center identified factors such as emergency surgeries, chest and heart procedures, and taxing operations affecting surgeons' schedules. These insights aim to optimize surgical scheduling, reduce waste, and improve patient outcomes.
Researchers suggest that frequent asteroid strikes may have kept the early Earth hotter and more unstable, making it difficult for rocks to survive. This led to a lack of preserved rocks from the first 500 million years of Earth's history, with long-lived continents forming only after impact intensity declined.
A unique plant fossil cache in New Mexico reveals angiosperms flourished 10 million years before dinosaurs' demise, contradicting the view that they only took over after their extinction. The discovery showcases a thriving forest dominated by flowering plants with large fruits, challenging the traditional narrative.
Researchers developed a perovskite/In0.47Ga0.53As thin-film heterojunction to create high-sensitive DUV-SWIR photodetectors with optimal stability and performance. The device achieved 98.9% retention of initial performance after 30,000 cycles.
Researchers discovered that bacteria pool their resources to help dormant cells survive antibiotic attacks. Protein transfer between bacterial populations allows vulnerable members to persist in the face of deadly antibiotic attacks. Understanding this teamwork can lead to new approaches to improve antibiotic effectiveness.
A new study calls for formal recognition of toxoplasmosis as a neglected tropical disease by the World Health Organization. The disease, which can cause permanent vision loss, affects one third of the world's population and has significant impacts on global health.
Researchers have determined the three-dimensional structure of human cone opsins in their dark state, shedding light on how they rapidly activate with light. This breakthrough provides new insights into human vision and its evolution, potentially offering new avenues for treating eye diseases.
Researchers at Seoul National University developed an automated design platform using generative AI to create complex DNA origami structures with curved and irregular geometries. The technology, Generative SNUPI, enables users to fabricate DNA nanostructures that can undergo shape transformations and be assembled modularly.
Researchers used an egg shuffle experiment to study the pied flycatcher's non-breeding areas. The results show that both genetic inheritance and hatching environment play a role in determining these areas.
A recent study analyzing Late Cretaceous fossils found diverse fruit and seed morphologies in flowering plants, challenging the traditional timeline for their reproductive evolution. The discovery expands our understanding of forest ecology and plant-animal interactions during angiosperm evolutionary history.
Researchers develop methodology to precisely design and control degree of disorder in nanopattern structures, enabling new possibilities for wave-controlling devices. The technology also reveals tailored physical properties for functional materials with wide-range control over disorder.
Researchers tracked pied flycatchers from eight countries and found that genes and environment influence their migration routes. The study suggests that the birds' wintering locations are determined by a mixture of inheritance and natal environment.
Researchers found that a specific enzyme, GELP80, helps create flexible guard cells in plants, allowing them to conserve water and survive longer drought periods. This discovery could aid in optimizing crops for better water management and greater resilience to drought.
A recent hantavirus outbreak on a polar expedition cruise ship highlights the risk of person-to-person transmission and the need for multi-sectoral coordination. The incident, which resulted in three deaths, underscores the importance of microbiome surveillance and ecologically informed travel health regulations.
A new framework tests AI reliability in antibiotic development, highlighting its potential to speed up the discovery of new antibiotics. The study found that while AI models were good at spotting known antibiotic structures, they struggled to explain their reasoning, a critical step towards trustworthiness.
A recent study reveals that vegetation's water-saving effect under rising CO2 is overestimated due to atmospheric feedbacks. This indirect impact can increase surface energy balance, leading to warming and enhanced atmospheric evaporative demand.
A research team developed a high-performance laser-based Three-Dimensional methane gas cloud imaging telemetry system. The system enables accurate measurement of emissions, supporting more efficient monitoring and control of pipeline networks.
A research team at Hefei Institutes of Physical Science developed a low-temperature solution-processing strategy for fabricating CuInS2 thin-film solar cells with an efficiency up to 12.28%, outperforming previous records.
Researchers develop Csp–π–d conjugated system to enhance oxygen reduction performance, outperforming platinum-based catalysts in stability and cost-effectiveness. The new catalyst facilitates electron transfer and weakens OH adsorption, promoting intermediate desorption and accelerating reaction kinetics.
The study reveals a nearly isotropic upper critical field in trilayer nickelate La4Ni3O10-δ under high pressure, unlike most layered superconductors. This unusual feature arises from the combined effect of two types of electronic states that balance out to lead to an overall nearly isotropic superconducting response.
The study reveals that lampreys share gene-expression patterns with mice across many regions, suggesting a well-organized brain in their common ancestor. The research also shows unique innovations in lamprey brains, such as oversized Müller cells, and highlights the evolution of specialized neurons over time.
Researchers discovered that plankton emissions form acidic vapors that trigger aerosol particle growth and cloud formation over pristine ocean regions. This finding improves climate models by accounting for previously overlooked gas methanesulfonic acid.
Researchers have resolved the atomic-scale interplay between hole transfer dynamics and water oxidation intermediates on faceted BiVO₄ particles. A critical hole density threshold dictates pathway bifurcation, with the (010) facet becoming catalytically superior above this threshold.
Researchers at Rice University developed a custom Python-based software tool to rapidly analyze data from high-resolution X-ray diffraction, identifying dislocations and irregularities in the atomic lattice. The approach can accelerate the development of more reliable electronic and quantum devices.
The study found that sepsis continues to be a significant cause of mortality in China, with infections accounting for the majority of deaths. The analysis also revealed age-related differences in sepsis burden, with older adults and males consistently carrying the highest risk.
A new study by Flinders University reveals that targeting specific pain receptors in the bladder can reduce debilitating effects of cystitis. The research suggests that activating certain cannabinoid receptors could provide relief from bladder pain and urinary urgency associated with interstitial cystitis/bladder pain syndrome (IC/BPS).
A team of researchers extracted and analyzed protein fragments from fossil teeth of Homo naledi, finding zero male markers. This discovery suggests a sex-bias in mortuary practice among non-human species, unlike observed in contemporary human cultures.
The Mount Sinai Adolescent Health Center has received the 2026 Community Health Improvement Award from HANYS, recognizing its decades-long leadership in comprehensive, confidential, equitable care for adolescents and young adults. The award honors the Center's commitment to improving public health and advancing health equity.
Researchers discovered a combination regimen of two β-lactam antibiotics resulted in faster and greater killing of bacteria than using each antibiotic alone. The pairing suppressed resistance to both antibiotics, offering a promising approach to optimising and personalising antibiotic regimens against life-threatening infections.
Researchers developed a new catalyst that accelerates water dissociation and hydrogen adsorption, enabling faster hydrogen evolution reaction activity and stronger stability. The study presents a TiO₂ QDs/Co₃O₄ symbiotic oxide support that precisely regulates Pt clusters for alkaline hydrogen production.
A team of researchers from Science Tokyo has developed a new method to reversibly switch the chirality of semiconductor materials using electrochemistry. This innovation enables the creation of spin-polarized currents in layered non-chiral semiconductors, opening up new directions for developing ultrafast and energy-efficient devices.
Jorge Íñiguez-González leads a €2.5M ERC Advanced Grant project to explore reconfigurable materials with tunable properties. The research aims to create adaptive technologies for information storage and next-generation computing.
Researchers developed an AI framework to identify viable target antigens for CAR T cell therapy, using publicly available single-cell RNA sequencing data. The framework showed robust tumor-killing activity in mouse models of multiple cancer types, including melanoma, leukemia, and colorectal cancer.
A Brazilian study found that 86% of children and adolescents with musculoskeletal pain recover, but 32% experience recurring pain. The study identified factors such as quality of life and age as predictors of recovery.
Researchers identified a distinct fibrotic fibroblast population in hypertrophic scars, which they linked to the transcription factor Yin Yang 1 (YY1). Restoring YY1 expression reduced scar-associated fibroblast activation, providing new insights into scar fibrosis and potential therapeutic strategies.
A cohort study found that a dietary pattern with lower inflammatory potential was associated with lower dementia risk among individuals with Alzheimer disease pathology. Targeted dietary strategies may help prevent dementia in those already at elevated risk.
A new study identifies key degradation mechanisms in perovskite solar cells, including phase segregation, copper corrosion, and edge patterns. Accelerated aging tests can accelerate these processes, but may not reflect real-world degradation.
The TREM-1 receptor amplifies innate immune responses and is a promising therapeutic target for inflammatory diseases. The review highlights its pathogenic roles in acute systemic inflammation and chronic conditions like inflammatory arthritis and neurodegenerative disorders.
The Sports Heat Tool, developed at the University of Sydney, provides personalized heat risk assessments for various sports. Users can input their location and chosen sport to receive a heat-risk score and practical steps to mitigate risks, taking into account factors such as temperature, humidity, and exertion.
A genome editing technique called base editing has been used to study the role of a master gene in human embryonic cells, revealing its crucial function in early development. The technique allows scientists to alter a single gene in human embryos, enabling them to better understand how human embryos develop.
Scientists at Universitatsklinikum Bonn developed a robust laboratory method to generate and study follicular regulatory T cells. The research found that TGF-β and IL-2 signaling pathways control the development of these cells, which regulate immune tolerance and antibody responses.
A team of scientists observed Jahn–Teller polarons in cobalt oxide crystals activated by tailored laser pulses. The study reveals the material's structural, electrical, and magnetic properties can be engineered using ultrafast laser pulses.
A study reveals that the rhythmic structure of laughter has remained constant in all living great apes, including humans, for at least 15 million years. This finding offers unexpected clues to the evolution of human speech, suggesting that sophisticated vocal control is a fundamental building block.
The Political Ecology Network will convene its biennial international conference POLLEN 2026 in Barcelona, Spain, from June 29 to July 3, 2026. The event will bring together researchers, activists, and creators to discuss contemporary crises and forge pathways toward peaceful alternatives.
Researchers found that puerarin significantly ameliorated serum biochemical abnormalities and histological changes associated with cholestatic liver fibrosis. The treatment promoted conjugation of hydrophobic bile acids into more hydrophilic forms, suggesting enhanced hepatic detoxification capacity.
Large language models can accurately identify reasons for medication discontinuation from doctors' electronic clinical notes, revealing that adverse reactions are a common cause. The study uses this approach to transform clinical free text into analyzable data, supporting evidence-based decision-making in health policy.
A new Cornell University study examines the relationship between cranial shape and body weight in dogs, identifying a link to syringomyelia, a painful spinal condition. Breeds prone to syringomyelia exhibit distinct skull shapes, highlighting the need for breed-specific treatment strategies.
Researchers at King's College London have developed an AI model that can improve a Formula One team's finishing position in simulations of the 2023 Bahrain Grand Prix. The model, which uses reinforcement learning and explainable AI, outperformed existing race strategy optimization techniques in many cases.
Researchers found that a daily spermidine supplement improved immune response to COVID-19 vaccination in older adults. Spermidine reduced markers of immunosenescence and stimulated autophagy, leading to higher antibody levels and better neutralizing activity against multiple viral variants.
Emerging evidence positions lactylation as a critical metabolic-epigenetic hub in lung cancer. Lactylation drives oncogenic programs and immune-evasion pathways, contributing to treatment resistance. Targeting this axis may restore treatment sensitivity.
A new study finds that young people from lower-income countries with limited internet access are at risk of being overlooked for mental health support due to climate change. This exclusion skews the evidence base, failing to adequately address the needs of those most affected by climate-related anxiety and depression.
Artificial intelligence is being harnessed to integrate multi-omics data from large-scale repositories such as TCGA and GDSC to decode tumour drug resistance. The review advocates for explainable AI frameworks, multimodal fusion strategies, and dynamic liquid-biopsy monitoring to address barriers to clinical adoption.
Researchers identified miR-29a as a pivotal regulator of cancer development, which can act as both a tumor suppressor and an oncogene. Natural bioactive compounds such as curcumin, EGCG, and resveratrol have been shown to restore normal miR-29a expression through epigenetic remodeling and inhibition of oncogenic signaling pathways.
A new study reveals rooftop solar panels can offset nearly half of increased electricity demand during peak cooling periods. Climate change alone is projected to push up residential cooling demand by 5%, but rooftop solar growth could halve this additional load, easing pressure on the grid.
Global newborn mortality from birth asphyxia and trauma has declined, but progress is slowing in low- and middle-income countries, particularly in sub-Saharan Africa. Countries with lower scores on human development indices experienced slower mortality declines, highlighting the need for targeted investments to close the equity gap.
A new prodrug and localized drug delivery platform have been developed by researchers to selectively target cancer cells. The platform uses carbamate masking of the 4-anilinoquinazoline hinge nitrogen to modulate exposure and enable controlled activation of EGFR-TKIs in tumour microenvironments.
A new artificial lateral-line sensing unit helps underwater robots estimate both magnitude and direction of local flow velocity. The sensor uses a flexible silicone spring, light-emitting diode, and photodiodes to detect subtle hydrodynamic changes in water flow.
Gramine, a natural indole alkaloid, exerts potent anti-tumor effects against triple-negative breast cancer (TNBC) by inducing ferroptosis. The compound selectively targets TNBC cells while sparing normal mammary epithelial cells.
The probiotic strain Lactobacillus rhamnosus CMU-pb-7 improves DN rats' condition, reducing total cholesterol and triglycerides. It reverses renal interstitial fibrosis and restores antioxidant capacity by activating the Nrf2/HO-1/Gpx4 pathway.
Research suggests that inhaled vitamin D can protect against dust, pollution, and pathogens in the lungs, potentially improving outcomes for those with chronic lung disease. Human clinical trials are needed to confirm these findings and explore the therapeutic benefits of direct lung delivery.
Researchers developed a frequency-domain thermoreflectance microscopy approach to visualize thermal conductivity and interfacial thermal conductance in thermal interface materials. The study reveals pronounced microscale heterogeneity, with high- and low-conductivity zones observed in particle-loaded thermal greases.
A recent study identified fPRDM16 as a potential therapeutic target for pulmonary fibrosis, linked to the decline of collagen-clearing capacity in lung fibroblasts with age. Restoring youthful levels of fPRDM16 may offer a promising approach to reverse persistent fibrosis.
Two new policy briefs support evidence-based decision-making in EU environmental policies, including the Nature Restoration Regulation and Biodiversity Strategy 2030. The briefs provide a framework for monitoring ecosystem pressures and recovery across the European Union.
Mayo Clinic researchers have identified a previously hidden step in the immune system's preparation to fight cancer, suggesting that the thymus plays a crucial role in training T cells before they enter circulation. This discovery could lead to more effective and longer-lasting cancer immunotherapies.
Researchers developed a new methodology to identify biomarkers for male infertility, enabling comprehensive analysis of lipids and metabolites. They found 955 potential metabolites and 473 lipids that could be present in sperm.
Researchers at Linköping University found that old oak trees and semi-natural grasslands are crucial habitats for many species. The study identified thresholds for habitat size needed to support species survival, providing conservationists with concrete data to prioritize cost-effective interventions.
A study found that supplementing with HMB before surgery improves liver regeneration in animals by preserving energy function and improving the quality of recovery. The supplementation was shown to have a beneficial effect on mitochondrial function and metabolic performance, even after it was discontinued.
A recent study published in JAMA Otolaryngology–Head & Neck Surgery reveals a higher incidence of smell and taste disturbances among GLP-1 RA users. The findings underscore the importance of regular monitoring and awareness to mitigate these adverse effects.
Researchers developed a compact, cost-effective diagnostic platform combining lensfree holography and deep learning for automated HER2 scoring. The system reached 84.9% accuracy for four-level HER2 classification and 94.8% accuracy for binary scoring, effectively lowering diagnostic risks.
JMIR Publications invites submissions on the 2026 Ebola disease public health emergency of international concern, focusing on response strategies, risk communication, and surveillance. The World Health Organization has declared a public health emergency due to population mobility and ongoing uncertainty in the Democratic Republic of th...
A recent review highlights the pivotal role of lactate and lactylation in PDAC progression, including their function as alternative metabolic fuel, signaling molecule, and epigenetic regulator. Therapeutic strategies targeting lactate metabolism offer promise, but clinical translation faces significant hurdles.
Researchers found that bariatric surgery can lead to a significantly higher risk of developing alcohol problems. The altered anatomy affects how the body processes and absorbs alcohol, leading to faster intoxication and prolonged recovery times.
Researchers discover a novel mechanism where PVT1 and EIF4A1 drive gastric cancer metastasis through the Notch-1 signaling pathway, resulting in increased tumour cell migration, invasion, and proliferation. Elevated STC1 levels confirm its role as a key downstream effector of this axis.
Researchers at Hiroshima University report a remarkable decline in chronic HBV and HCV cases, from 3.0-3.07 million to 1.1-1.4 million between 2000 and 2020. Projections suggest the number of HBV infections will drop to around 200,000 cases by 2050, while HCV is estimated to decline to fewer than 20,000 cases.
The 2026 Warren Alpert Foundation Prize was awarded to five scientists who developed curative genetic therapies for two major blood disorders. These treatments, CASGEVY and LYFGENIA, have been approved by the FDA for use in the US and have shown significant advancements in the field of gene therapy.
Research finds that millennials' fear of growing up decreases as they age, while younger generations report higher maturity fears. The study, published by the American Psychological Association, suggests that broader societal factors such as economic uncertainty and social pressures shape how young people view adulthood.
Scientists have discovered a way to track whales using fiber-optic cables by detecting low-frequency pressure waves generated by their movement. This method allows researchers to identify whale tracks even when the animals are not vocalizing, expanding their capabilities for remote sensing applications.
A WSU study explores the environmental cost of influencer PR gifts, finding that only 1% of comments mention packaging sustainability. The research suggests influencers can promote eco-friendly behaviors by discussing sustainable practices in their unboxing videos.
A recent study evaluated the safety and effectiveness of the J-Valve Transfemoral System in treating symptomatic severe aortic regurgitation. The study showed sustained valve performance, meaningful symptom improvement, and evidence of reverse left ventricular remodeling at one year.
Researchers have uncovered a potential strategy to eliminate cancer cells that survive KRAS inhibition, preventing relapse. By targeting the metabolic pathways that support the survival of drug-tolerant persister cells, treatment regimens could be designed to shrink tumors and prevent cancer recurrence.
A study found that discussing from a third-person perspective in virtual environments improves consensus agreement, accuracy in understanding others' opinions, and reduces intragroup conflict. However, it also decreases emotional connection among participants.
A pilot study found that an examiner-worn, neck-mounted camera can supplement the observation and review of clinical skills during OSCE assessments. The results showed moderate to strong agreement between live and video-based assessments, with the wearable camera enabling more observations to be evaluated than the fixed camera.
Researchers identify OsFeSOD3 gene that supports chloroplast health while enhancing plant survival under drought conditions. This discovery could help overcome crop yield limitations and improve climate-resilient crops.
Researchers identified karyoptosis as a key link between toxic protein accumulation and neuron death in neurodegenerative diseases like Alzheimer's and frontotemporal dementia. The study found that targeting proteins acting as 'switches' in this pathway may slow or prevent cell death by karyoptosis.
Research from the University of Michigan shows that switching to fuel cells or batteries can reduce lifetime greenhouse gas emissions by up to 90% compared to diesel-powered vehicles. The study found that hydrogen fuel cells and battery electric powertrains offered the largest emissions reductions.
Researchers reveal a previously unrecognized form of actin self-organization that may help explain how cells spontaneously generate shape and movement. Live-cell imaging and computational modeling show that these self-propelled treadmilling actin filaments (SpTAs) drive cellular protrusions through a process powered by treadmilling.
New therapies using regulatory T cells, known as Tregs, could target diseases with inflammation, such as cancer and autoimmune conditions. Early evaluations show good tolerance and safety profiles, but precision is key to tailoring treatments for specific patients.
Elsevier's ClinicalKey Student now incorporates StudyFinder AI, providing students with access to trusted, evidence-based content and eliminating risks associated with generic AI tools. This enhancement aims to support medical students in making clinical decisions by leveraging verified sources from Elsevier textbooks and NICE guidelines.
A new study has found that changes in a senior dog's gait can be an early warning sign of dementia. The research tracked the stride length of 88 geriatric dogs over time, revealing a significant decrease in front leg stride length with worsening cognitive decline. This change was found to be more pronounced than age-related decline alone.
Researchers discovered biomarkers indicating overactivity and dysfunction in the immune system, which can lead to chronic critical illness. Identifying these markers could allow doctors to intervene earlier, leading to shorter ICU stays and improved patient outcomes.