A new study from the Medical University of South Carolina suggests that the complement system, a part of the body's innate immune system, plays a major role in brain damage after repeated concussions. The research found that reducing complement activation can help protect the brain and reduce cognitive impairments.
Researchers developed DeepForest AI to capture under-canopy vegetation using synthetic-aperture imaging and 3D neural networks. The technology improves deep-layer reflectance accuracy by 2–12 times and supports vegetation-index calculation for ecological monitoring.
Researchers developed a method to efficiently identify and select haploid seeds in wheat using double-fluorescent proteins. The system, which combines fluorescence-based identification with molecular markers, allows for accurate detection of haploids independent of the recipient's genetic background.
Researchers created a comprehensive atlas of active autonomous TIR transposons across 1,007 plant genomes, revealing a strikingly uneven distribution and lineage differentiation patterns. This study provides critical insights into transposon-host coevolution and delivers a rich resource for plant biotechnology.
Researchers found that humic substances formed at higher temperatures stimulate microbial carbohydrate metabolism and promote the accumulation of antibiotic resistance genes (ARGs) in soils. The study highlights a balance between soil carbon sequestration and ecological risk, emphasizing the need for sustainable residue-return practices.
A team of scientists proposes a new scheme for 1D DTQW systems with coherent multiple long-range connectivity in the synthetic frequency lattice. This enables faster diffusion speed and breaks the weak coupling limit, facilitating quantum gate operations.
Researchers demonstrated that 40-Hz auditory stimulation significantly elevates beta-amyloid levels in the cerebrospinal fluid of aged rhesus monkeys, with effects persisting for over five weeks. The study provides evidence supporting 40-Hz stimulation as a non-invasive therapy for Alzheimer's disease.
Scientists have created a high-performance cathode material for aqueous zinc-ion batteries by converting a layered MXene into an amorphous form. The new material, a-V₂CT_x, shows remarkable improvements in capacity, charging speed, and durability.
The journal is seeking original research on sustainable finance, including ESG considerations and climate risk, to capture recent advances in the field. Contributions will inform professional practice and policy development at both national and international levels.
A study demonstrates that combining silybin and carvedilol synergistically suppresses hepatic stellate cell activation and reverses liver fibrosis by targeting Wnt4/β-catenin signaling. This clinically feasible combination strategy has a promising new therapeutic approach for liver disease.
A recent study by HKUMed found that most hospital patients in Hong Kong have little to undetectable levels of neutralizing antibodies against the mutated H3N2 strain. The research team recommends early vaccination to reduce the risk of severe infection and emphasizes the importance of prompt medical care if infected.
Researchers identified a protein called Piezo1 that acts as the body's 'exercise sensor', detecting mechanical signals from physical activity to maintain strong bones. Activating this pathway may lead to the development of drugs that mimic exercise benefits for individuals with limited mobility.
High levels of ADARdd overexpression lead to abundant off-target RNA editing in rice protoplasts, characterized by pronounced stochasticity and low efficiency. The study provides guidelines for improving RNA editing accuracy in plants and highlights the need for rigorous validation of proximity-directed RNA editors.
A new sample prior based point spread function (PSF) decoupling method enables accurate system characterization without theoretical assumptions. Regular biological samples act as modulators to optimize the system PSF, allowing non-parametric and adaptive imaging.
HKU three research projects named among ‘Top 10 Innovation & Technology News in Hong Kong 2025’; a dual immunotherapy improves liver cancer survival rates, a hybrid photosensitive immunotherapy targets skin cancer, and the detection of newborn neutron star's 'heartbeat'.
A new pipeline, NLRSeek, identifies previously overlooked NLR genes in sequenced genomes, revealing functional genes and driving evolutionary expansion in non-model species. This tool enhances disease resistance breeding by providing a more complete set of NLRs.
The study developed a novel method, BacPhase, for constructing bin markers and genome phasing in polyploid crops. By using PacBio HiFi long-read sequencing, researchers generated high-confidence bin markers in potato, achieving 59.58% scaffold anchoring to chromosomes.
The quota_Anchor tool identifies collinear genes with control over alignment depth, revealing less similar expression patterns in relatively inverted genes. It also finds stronger purifying selection in these genes.
Researchers have developed a non-invasive technique, fast raster-scan optoacoustic mesoscopy, to observe microvascular endothelial dysfunction at the single-capillary level. The study found that this technology can resolve dynamics of individual cutaneous capillaries and provide better inter-day repeatability compared to existing methods.
A team led by Professor Leo Tianshuo Zhao developed the world's smallest fully printed infrared photodetectors, overcoming silicon-based technology limitations. The innovation uses a nano-printing platform to assemble solution-phase colloidal nanocrystals and create advanced optoelectronic devices.
Researchers have developed a novel approach to quantum memories using 3D-nanoprinted light cages filled with atomic vapor. The technology enables highly efficient conversion of guided light pulses into collective atomic excitations, with storage durations of several hundred nanoseconds. The platform's compact size and room-temperature ...
Researchers developed a triple-electrode integrated functional electrode for synchronized monitoring of neural signals and dopamine release during sleep-wake transitions. The study highlights the critical role of dopamine in regulating sleep-stage transitions and identifies distinct neuronal populations involved in this process.
ChargeFabrica, a Python-based simulation framework, models mesoporous perovskite solar cells in two dimensions to predict performance and understand charge transport mechanisms. The tool replicates experimental trends and enables optimized device design, paving the way for enhanced stability.
A Hong Kong-based educator won a Gold Award for his innovative teaching project, using immersive video gaming to enhance medical students' self-competence in coping with death and dying. The award recognizes the educator's efforts to promote emotional resilience and holistic growth among learners.
The University of Hong Kong (HKU) and Tsinghua University have expanded their partnership across five key areas: public health, engineering, law, and astronomy. The institutions aim to foster frequent and productive academic exchanges to nurture globally competitive talent.
The study identifies GmWOX1a and GmWOX1b as key regulators of mediolateral polarity in compound leaves. Multiple knockout mutants show altered leaf shape and reduced area, highlighting the functional redundancy among WOX1 genes.
Academician Yu-Zhong Wang's team proposes a novel recycling method that degrades polyethylene into oligomers, which are then assembled with functional monomers through dynamic imine bonds. The resulting material exhibits excellent mechanical properties and multiple functions such as flame retardancy, antistatic properties, and UV shiel...
Researchers at Northwestern University discovered a hidden molecular control switch inside the protein TRPM5, which regulates taste, blood sugar control and gut health. The switch can be activated or inhibited by small molecules, unlocking new opportunities for therapeutic development.
A high-resolution study of Jurassic mudstones in China's Sichuan Basin has discovered that astronomical cycles control climate, sedimentation, and organic matter accumulation. The research provides a detailed climatic and sedimentological framework that enhances the predictability of shale oil reservoirs.
Researchers detected Pteropine orthoreovirus (PRV) in five patients in Bangladesh with symptoms consistent with Nipah virus infection. The study highlights the importance of broad-spectrum surveillance programs to identify and mitigate public health risks from emerging bat-borne viruses.
Boston College researchers have developed an AI-assisted method to remove 'noise' from functional MRI brain data, a major obstacle for fMRI research. The new method, known as DeepCor, outperforms previous approaches and could pave the way for new discoveries about the brain and its disorders.
Researchers provide a comprehensive framework for removing emerging contaminants from wastewater through advanced oxidation processes. Key findings highlight the importance of understanding reaction pathways to optimize treatment systems.
A team of researchers from Rice University discovered that lakes on ancient Mars could persist under thin seasonal ice for at least decades, contradicting earlier climate models. The study suggests that surface features shaped by sustained liquid water coexist with the idea that early Mars was too cold to support such conditions.
A large population-based study found that SGLT-2 inhibitors reduced the risk of diabetic foot problems compared to GLP-1 receptor agonists. The difference was mainly due to fewer cases of nerve damage in the feet among SGLT-2 inhibitor users.
Climate change is altering the global nitrogen cycle, affecting food security, water quality, and biodiversity. The review finds that elevated CO2 boosts plant growth but dilutes protein quality, while rising temperatures reduce yields and increase nitrogen losses.
A Northwestern University study reveals that 2.3% of women experience unusual physical and emotional responses during orgasm, including laughter, crying, headaches, and more. These peri-orgasmic phenomena are normal but rare, with most women experiencing them only sometimes with orgasm.
A new study uses hyperspectral sensing and machine learning to analyze grapevine leaves for nutrient deficiencies. The approach delivers fast, non-destructive results with high spatial resolution, opening the door to earlier detection of nutrient imbalances and more targeted fertilization.
Researchers identified common aging-related alterations in genes involved in RNA splicing and processing across eight human tissues. These findings suggest a shared biological response to aging, pointing to the importance of RNA processing in accurate protein production.
Researchers found that narrative-only feedback was perceived as the fairest and provides clearer understanding of how to improve future performance. Purely numerical feedback without context can make employees feel negatively evaluated and is considered unfair.
Researchers from UC Irvine discover a DNA repair mechanism enabling Greenland sharks to maintain their vision for centuries despite extreme low-light conditions. The study challenges current understanding of aging, vision, and longevity, offering new insights into preserving vision as we age.
Researchers from UCL discovered a way to grow bacterial cellulose from beer waste, creating edible scaffolds for cultivated meat. The new approach could make lab-grown meat more sustainable and cost-effective.
Scientists have developed a groundbreaking system called Stomata In-Sight that allows them to watch and quantify plant respiration in real-time. This breakthrough could lead to more efficient crops that require less water to grow, crucial for food security in drought-stressed regions.
Researchers discover Vitamin A metabolite retinoic acid compromises anti-cancer immune response, but develop inhibitor KyA33 to restore DC maturation and function. The compound boosts efficacy of dendritic cell vaccines in preclinical studies.
A new study finds that infants' brain activity is influenced by their caregivers' reported income sufficiency, with delayed maturation seen in households where income was never adequate. The research suggests that policies strengthening families' basic needs during infancy may have lasting developmental benefits.
A study found that economic crises can have lasting negative impacts on children's physical development, including stunted growth and increased risk of obesity. The research used the Asian financial crisis in the 1990s as a case study, demonstrating how food price shocks can affect children's body measurements until they are young adults.
A recent study found that muscle impairment from anorexia nervosa persists even after weight regain, with significant reductions in muscle size and strength. This could have implications for treatment strategies and outcomes for individuals recovering from the condition.
A Cornell psychology professor argues that people make decisions based on intuition and core values rather than facts. Research found that considering the overall sense of risks and benefits (or
The Nanalysis Edition of KnowItAll combines Wiley's analytical software platform with Nanalysis' specialized NMR database, streamlining spectral interpretation workflows for users. The tailored solution provides immediate access to reference spectra optimized for benchtop NMR instruments, expanding compound identification coverage.
Researchers discovered a new class of highly interactive LINE-1 loci that modulate cancer gene expression by altering three-dimensional genome architecture. These structural changes allow for high-level expression of genes driving cancer cell proliferation.
The study proposes a unified genetic and descriptive framework for delta-beach bar composite systems, highlighting four principal distribution patterns. These patterns reflect specific geomorphic and hydrodynamic settings, controlling where and how these sand bodies develop.
A new review highlights how converting biomass into gaseous fuels like hydrogen, methane, and syngas can play a critical role in the global transition to low-carbon energy systems. Biomass-based gaseous fuels can be used for electricity generation, industrial heat, transportation, and as building blocks for chemicals and synthetic fuels.
Researchers have released guidelines for diagnosing and monitoring CCDS in senior dogs, offering practical diagnostic criteria and standard definitions. The guidelines are designed to aid both clinicians and researchers in helping dogs with cognitive issues, paving the way towards improved diagnostics and therapeutics.
A new study uses high-throughput, non-destructive μ-XRF-based phenotyping to dissect the genetic control of seed mineral nutrition and morphology. The approach identifies 17 significant loci linked to essential mineral content and seven associated with seed shape traits.
The CHSN01 jacket material has achieved an average yield strength of 1560 MPa at 4.2 K, setting a new benchmark in cryogenic steel properties. This breakthrough demonstrates exceptional mechanical properties, non-magnetic nature, and high-strength performance under extreme conditions.
Researchers from Japan successfully downscaled a total ferroelectric memory capacitor stack to just 30 nm, maintaining high remanent polarization and paving the way for compact and efficient on-chip memory. This breakthrough demonstrates compatibility with semiconductor devices and paves the way for future technologies.
Researchers used computer modeling to reconstruct the spatial transmission of the 2009 H1N1 flu and COVID-19 pandemics in the US, highlighting challenges of early outbreak containment and identifying key transmission hubs. The study suggests expanding wastewater surveillance coverage could slow initial spread of future pandemics.
The Maize-IRNet model uses deep learning to evaluate maize haploid fertility restoration with high accuracy, reducing labor demands and observer bias. The system supports rapid, standardized, and reproducible field assessments of haploid genome doubling and spontaneous genome doubling.
A new metal-free route for fully recycling PET into premium chemical feedstocks has been developed, overcoming long-standing barriers of incomplete depolymerization and low product purity. The method uses an ionic liquid catalyst and achieves complete PET conversion, delivering high yields of valuable chemicals.
A groundbreaking study demonstrates that Alzheimer's disease biomarkers can be accurately detected using simple finger-prick blood samples collected at home. The research, led by Banner Health and the University of Exeter Medical School, successfully tested 337 participants and proved the accuracy of this accessible testing approach.
Bucknell researcher Chris Martine identified a new species of bush tomato, Solanum nectarifolium, with specialized organs that produce sweet liquid to attract ants. This is the first known Solanum species with visible extrafloral nectaries, marking a significant discovery in biodiversity science.
Researchers created a comprehensive clinical database to predict NAFLD using facial images, physical examinations, and laboratory tests. A multimodal-based prediction method, DeepFLD, was proposed, achieving superior performance compared to models relying solely on metadata or facial images.
A forecasting study found that the Inflation Reduction Act will save approximately $400 million on Louisiana Medicare diabetes drug costs over five years. Patients are expected to switch from non-negotiated to negotiated drugs due to lower costs, resulting in significant savings.
A cross-temporal, multinational study found that people's beliefs about women and men reflect the social roles they occupy in homes and workplaces. Stereotypes of men as assertive and ambitious and women as kinder and more caring persist despite growing female workforce participation.
A groundbreaking study from Northwestern University found that changes to the gut microbiome can change the way the brain works across different primate species. The researchers discovered patterns of gene expression associated with conditions like ADHD and schizophrenia in mice with microbes from smaller-brained primates.
A study highlights the opportunity for orthopedic surgeons to identify patients who have experienced intimate partner violence (IPV), with only 0.3% of referrals compared to 29% from emergency departments. Orthopedic teams can educate and empower patients, providing timely life-saving referrals.
A new study from GreenDrill reveals that the Prudhoe Dome ice cap melted approximately 7,000 years ago due to mild Holocene-era temperatures. This finding highlights the region's vulnerability to human-induced climate change and has significant implications for sea level rise predictions.
A newly designed mechanophore, called DAANAC, was developed to provide early warning against mechanical failure while resisting heat and UV. It features a stable and fluorescent diarylacetonitrile radical coupled to an alkoxycarbonyl radical that quenches fluorescence.
Researchers describe a new species of spider-parasitic mite found on juvenile spiders in the Butantan Institute collection in Rio de Janeiro. The larvae were collected and examined using microscopy techniques, resulting in the first description of this family in Brazil.
This study found that US youth spent more than an hour using smartphones during school hours, primarily for social media use. Objective findings from a large sample confirm previous self-report studies, highlighting the need for responsible smartphone use among adolescents.
Researchers have discovered a unique cobalt-based molecule that can function as a spin quantum bit, providing a new design strategy for molecular materials used in quantum information technologies. The molecule exhibits slow magnetic relaxation and delocalized electron spins, allowing it to stabilize the quantum state.
A University of Bonn study has shown how the fungus Ustilago maydis takes over the plant's lateral root formation function, leading to massive tissue growths that divert energy and resources from defense. The findings provide valuable insights for breeding more resistant varieties of maize.
Researchers found early medieval migrants came from the Mediterranean and Arctic Circle, with a significant spike in male migration and female mobility in the 7th-8th centuries. The study provides new evidence on the nature and scale of early medieval migration, showing that population movement was a consistent feature throughout England.
A retrospective insurance claims analysis found a high prevalence of polypharmacy among children under 15 in Côte d'Ivoire, with regional disparities evident. The study highlights the need for targeted interventions to reduce polypharmacy risks and costs across all regions.
Researchers found that ovarian cancer transforms the omentum into an environment that favors tumor spread. The study analyzed tissue samples from 15 patients and created a cell atlas of the omentum in diseased and healthy states.
A new study found that historic buildings in English cities enhance scenicness, with scores 25% higher than the average urban score. The study's findings suggest that heritage designations and architectural significance are key factors influencing scenic beauty.
A multi-center observational study found that households facing food insecurity and challenges like low social support had a significantly higher risk of long COVID. Healthy diets may protect against the risk, highlighting the need for addressing adverse social factors in disease prevention.
Researchers discovered that centimeter-long aquatic worms can spontaneously collect and organize particles in their environment through natural undulating motion. This behavior emerges from the flexibility of the worms and does not require a brain or complex interaction.
The new guidelines update past recommendations to focus on 30-year-old women with risk factors, while simplifying screening for younger and older populations. The changes aim to reduce overtreatment and improve health outcomes for cervical cancer patients.
Andreas Zeller recognized for his work on automated debugging and security testing, with a total of nine Test of Time Awards. He is one of the few researchers to receive two ERC Advanced Grants from the European Research Council.
Researchers at Columbia University developed an inhalable nanotherapy called BEAT that delivers two therapeutic proteins to the lungs to target cancer cells. The treatment showed better retention in the lungs and dramatically suppressed tumor growth compared to a systemically delivered approach.
A long-term study in Türkiye examines wolf–human interactions, revealing that conflicts cluster in areas with widespread rural livestock farming. The research highlights the impact of human-driven factors such as road networks and habitat fragmentation on conflict risk.
A large patient population study found that weight gain increases the risk of developing low back pain, with a 7% increase in risk for every BMI unit or 10 pounds over ideal weight. The study suggests maintaining a healthy weight or BMI may help avoid low back pain.
A new peer-reviewed paper by Drs. Steven N. Austad and Giovanni M. Pes validates decades of demographic research on the world's longest-lived populations, using rigorous validation criteria to confirm their exceptional human longevity.
Researchers have discovered a linear relationship between reactivity and the reciprocal of uranium concentration in thermal-spectrum molten salt reactors. This finding has significant implications for criticality calculations, fuel loading prediction, and reactivity measurement.
Researchers at Ben-Gurion University have developed a new type of plastic-like material that can be activated with light or gentle heat. The materials, known as latent monomers, remain inactive for weeks before solidifying into a durable plastic-like substance. This switchable system could give rise to hundreds of new plastic-like mate...
A recent study found a substantial COVID-19 burden in the US between October 2022 and September 2024, with adults 65 years and older particularly affected. The study's results underscore the importance of continued prevention efforts to mitigate the impact of COVID-19 on this vulnerable population.
A study led by Professor Michael Glickman and postdoctoral researcher Dr. Ajay Wagh found that brain cells transfer toxic UBB+1 protein to neighboring neurons through a mechanism involving p62, potentially accelerating Alzheimer's disease spread
Researchers have found a galaxy cluster with scorching hot gas just 1.4 billion years after the Big Bang, five times hotter than predicted, and containing three supermassive black holes that pumped energy into the surroundings. This discovery could upend current models of galaxy cluster formation and evolution.
A large-scale international study has deciphered a mechanism enabling breast cancer to metastasize to the brain. Researchers identified a specific chromosomal alteration predicting high likelihood of brain metastases and found that the absence of functional p53 gene impairs brain environment adaptation.
Researchers developed a portfolio optimization framework to maximize offshore energy production by identifying optimal locations for wind turbines and marine hydrokinetic technologies. The study found that combining these technologies in suitable locations can significantly reduce costs and increase energy stability.
Scientists develop subseasonal forecasting tools to provide timely, actionable information for governments and industries. These forecasts offer a 'sweet spot' between short-term precision and long-term planning.
Long-term ecological research faces severe threats from lack of funding, data manipulation, and political interference. The report highlights the need for institutional support to establish trustworthy facts and inform policy.
Researchers discovered that sevoflurane impairs neurogenesis and cognitive function by inhibiting fatty acid β-oxidation in neural stem/progenitor cells. Enhancing FAO activity in NSPCs attenuates sevoflurane-induced neurogenesis impairment, suggesting a new mechanism of sevoflurane neurodevelopmental toxicity.
A new study from Brown University researchers reveals that private equity firms have acquired over 500 autism therapy centers across the US, with a focus on states with high rates of autism diagnoses. The findings raise concerns about the potential impact on access to treatment and the quality of care for families seeking services.
A new platform, RootXplorer, enables accurate whole-root-system assessment of soil penetration, critical for breeding crop varieties resilient to soil compaction and drought. The system uses a standardized approach to mimic mechanical impedance and identify genotypes with contrasting tolerance to compaction.
A study applies a multi-criteria decision analysis framework to evaluate three orphan medicinal products, laronidase, emicizumab, and dimethyl fumarate, with highly consistent quantitative scores. The framework offers a transparent and multi-faceted approach to evaluating high-impact drugs for rare diseases within reimbursement systems.
Researchers at Fritz Haber Institute have made significant strides in understanding fuel-cell catalysts under industrially relevant conditions. They discovered that the rate-limiting steps and their degree of rate control change as a function of overpotential and pressure, challenging traditional views on multi-step reactions.
The January 2026 issues of four American Psychiatric Association journals feature groundbreaking research on externalizing disorders, pediatric anxiety, autism, and inflammation-related depression. The studies also explore the potential benefits of psychedelic therapy in suicide prevention.
A new approach enables efficient, real-time wheat phenology detection using compact models and knowledge distillation. The method achieves high accuracy while reducing data and computational demands, suitable for practical agricultural deployment.
Researchers discovered that nicotinic acid can dramatically reduce liver damage caused by ischemia-reperfusion injury. The compound targets damaged mitochondria, reducing markers of liver injury, suppressing inflammation, and promoting mitophagy and mitochondrial biogenesis.
A new study reveals that microplastics are impairing the oceans' ability to absorb carbon dioxide, a process crucial for regulating Earth's temperature. Microplastics also disrupt marine life, weaken the biological carbon pump, and release greenhouse gases as they degrade.
Scientists create natural surfaces with 3D nanowrinkles that control light, liquids, and living cells. The method uses laser polarization to guide the material's organization, enabling precise control over wrinkle formation and applications in bio-inspired surfaces and sensors.
Researchers created a calculator to assess multilingualism, using formulas that consider age of language acquisition and self-rated proficiency. The tool yields scores indicating language dominance and degree of multilingualism, offering a clear and transparent way to understand individual language strengths.
Researchers developed an injectable paste derived from human skin cells to restore breast volume after tumor removal, with less scarring and shorter healing time. The material promotes blood vessel growth and tissue remodeling while keeping inflammation low, making breast reconstruction safer and more accessible.
A CRISPR screen identified 331 essential genes for brain cell generation, including PEDS1 linked to a severe developmental disorder. The study provides a new approach to identifying genes involved in neurodevelopmental disorders like autism and offers insights into gene inheritance patterns.
A new clinical trial, RECIPROCAL, seeks to optimize targeted radiation therapy for men with advanced prostate cancer by adjusting treatment based on individual PSA levels. The trial aims to minimize side effects while preserving survival benefits.
Researchers at ISTA have found that the zebrafish embryo's geometry is essential for its development, guiding cell division and gene activation. The study's findings could improve IVF embryo assessments by understanding how the embryo interprets its geometry.
A new study found that a drug mimicking the hormone progesterone, megestrol, has anti-cancer activity when used with conventional anti-oestrogen treatment for women with breast cancer. This combination showed a greater decrease in tumour growth rates compared to those treated with an anti-oestrogen only.
The SHASAI project addresses cybersecurity risks in AI systems from design to real-world operation, combining secure hardware and software, risk-driven engineering, and real-world validation. The project will demonstrate its methods and tools in three diverse scenarios, supporting Europe's efforts to promote trustworthy AI.
A team of researchers successfully observed the birth and decay of a highly active solar region, known as NOAA 13664, over three solar rotations. The study provides new insights into the formation and effects of superactive regions on the sun, shedding light on their potential impact on Earth's technology and environment.