A new study from Duke University found that even mild stress before surgery can lead to delirium, uncontrolled pain, and longer hospital stays in older adults. Over 40% of patients reported moderate to high distress levels similar to those with advanced cancer.
A new synthesis of seismic research shows that AI combined with physical principles is rapidly transforming how scientists image the Earth's shallow and crustal structures. The study highlights the need for physics-guided AI frameworks that balance computational efficiency with interpretability.
Researchers have developed a new piezo-photocatalytic material that dramatically improves the removal of carbamazepine from water. The oxygen-doped MoS₂ catalyst achieves rapid and complete degradation within minutes, outperforming conventional photocatalytic approaches.
Insilico Medicine collaborates with Servier to develop novel therapeutics in oncology through AI-driven platform Pharma.AI. The partnership is focused on identifying promising targets and generating molecular structures with desired properties.
Recent advances in CAR-NK cell therapy have expanded its applicability across hematological malignancies, solid tumors, autoimmune diseases, and infectious conditions. CAR-NK cells offer a unique balance between efficacy and safety, with potential applications in cancer and immune-related diseases.
Recent advances in maternal vaccines and long-acting monoclonal antibodies have broadened the scope of RSV prevention, reducing disease burden and improving infant survival outcomes. The expert panel concludes that both strategies demonstrate strong benefit–risk profiles when used appropriately.
A team at East China Normal University directly observes femtosecond-scale quantum coherence transfer from an external laser field to microcavity exciton-polaritons. The study confirms that decoherence in the exciton reservoir is key to losing original coherence.
Researchers have developed a novel class of biomass-derived carbon dots that selectively eradicate Staphylococcus aureus in water. The nanomaterials preferentially bind to pathogen-specific cell wall components, triggering localized oxidative stress and membrane damage while sparing non-target bacteria. This approach offers a sustainab...
A new study has found that membrane filtration is a superior method for collecting submicron aerosols, including bacteria, fungi, and viruses. The research provides practical guidance for accurate airborne pathogen monitoring in hospitals, schools, and other high-risk indoor environments.
The study reveals that SMX enhances nitrous oxide emissions, which are nearly 300 times more potent than carbon dioxide. This increase occurs due to the suppression of nitrogen removal and stimulation of incomplete denitrification in sediments, leading to a significant impact on coastal ecosystems.
The study identifies profound immune dysregulation, chronic inflammation, and impaired cytotoxic function in lymphatic malformations. A Shared CD14⁺CD16⁺ Monocyte Expression Program (SMEP) is uncovered, pinpointing S100A8 as a key druggable target for therapeutic intervention.
The liver's unique immune tolerance is driven by peptide hormones and bile acids, which activate anti-inflammatory responses and foster a tolerogenic phenotype in resident immune cells. This mechanism may explain the liver's reduced rates of transplant rejection but also poses challenges for treating liver infections.
This study reveals how lipid metabolism dysregulation promotes colorectal cancer liver metastasis through a novel YTHDF3-mediated mechanism. Lipid deposition enhances YTHDF3 expression, leading to its degradation and reduced PPARα, which decreases fatty acid oxidation metabolites.
A recent study reveals that FPR2 activation regulates the proliferation and differentiation of intestinal stem cells (ISCs) and transit-amplifying cells, leading to improved epithelial repair. The study also identified a potential therapeutic target for intestinal damage, highlighting the therapeutic potential of FPR2 agonists.
Plant-derived compounds interfere with bacterial quorum sensing to reduce human bacterial pathogens and antibiotic resistance in agricultural soils. The study shows that plant extracts can substantially reduce risks posed by these microbes by disrupting their communication and sharing harmful traits.
Researchers propose that self-sabotaging behaviors like procrastination and perfectionism are rooted in the brain's survival instincts. By processing underlying emotional pain, individuals can break free from self-sabotage loops through self-compassion.
The study investigates regional mechanical variability in porcine pia–arachnoid complex (PAC) using a region-by-region, multi-scale design. Regional differences in mechanical properties are linked to biochemical distributions via two-photon imaging and RNA-seq.
The review explores how multiplayer games, social robots, and virtual agents can advance artificial empathy in therapy and healthcare by embedding interpersonal interaction. It highlights the need for deeper, more seamless closed-loop interaction and emphasizes the importance of emotion recognition, trust, engagement, and rapport.