Researchers sequenced the Great Basin bristlecone pine genome, revealing genes associated with disease resistance and longer telomeres, potentially holding clues for understanding longevity in other species. The study provides a reference genome sequence that can be used to inform modern genetic discovery.
Researchers found that mild hypoxia in preterm babies can compromise neural communication, impacting the hippocampus region responsible for memory and learning. Abnormal neuronal maturation and loss of synaptic function may lead to academic difficulties and behavioral concerns later in life.
A new study found that walking pace is a strong predictor of mortality risk, especially in people with existing health conditions. Combining walking pace with other physical measures improved mortality predictions, suggesting a simple and cost-effective way to identify high-risk individuals.
Researchers found that A. niger can recover nearly 40% of trapped phosphorus within 15 days through microbial metabolism and selective mobilization. This bioextraction strategy has the potential to transform industrial waste into a valuable agricultural resource, reducing dependence on finite phosphate rock reserves.
Optical biosensors offer promising solutions for rapid, portable, and on-site pesticide detection. Key biorecognition elements such as enzymes, antibodies, aptamers, and molecularly imprinted polymers enable high-selectivity detection and minimize environmental impacts.
The HKU Primary Health Care Academy has been designated by the World Health Organization (WHO) as a Collaborating Centre for health and nursing workforce development in primary care. The centre will support workforce development and health system transformation through capacity building, research, and knowledge exchange.
A HKU study has discovered a previously overlooked process controlling phosphorus availability in ancient iron-rich oceans. Phyllosilicate minerals effectively trap dissolved phosphate on their surfaces via an 'Fe(II) bridging effect', removing essential nutrients from seawater and limiting marine life.
Researchers at Flinders University have developed a sustainable biopolymer mixture from tung oil acid emulsion to seal cuticles and increase elasticity in damaged hair. The new application has the potential to reduce breakage and improve hair health, set to join the growing natural personal care product pipeline.
The University of Hong Kong has signed a Memorandum of Understanding with the Phoenix Yuen Foundation Fund Limited to enhance education and student development. The donation reflects the shared values of dedication to education and the arts, strengthening HKU's mission to nurture creative leaders.
The Shanghuang Observatory is a key research center for atmospheric physics in China, playing a crucial role in enhancing the country’s weather forecasting capabilities. The observatory has made significant contributions to improving weather prediction models, supporting disaster prevention and mitigation efforts.
Researchers developed inch-scale, binder-free ultrahard diamond wafers with Vickers hardness exceeding 200 GPa. The ultra-hard diamond wafer exhibits outstanding wear resistance and structural stability, making it suitable for applications in extreme-environment electronics, advanced manufacturing, and semiconductor thermal management.
The University of Hong Kong Libraries and the Chamber of Young Snow have signed a 10-year MoU to advance Chinese cultural education and foster cross-cultural understanding. The partnership aims to strengthen HKU Libraries as a cultural hub and support CYS's mission to elevate Chinese heritage.
Researchers at Tohoku University discovered a way to control tiny magnetic properties using electric current, paving the way for new computing technologies. This approach stabilizes spins in energetically unfavorable states, allowing for more flexible data storage.
Researchers at The University of Osaka discovered that the cyanobacterial circadian clock is controlled by factors intrinsic to one protein, which remains stable under different conditions. This finding offers significant insight into how living organisms measure time.
Researchers identified two types of extreme warm events: warm-wet and warm-dry, with distinct underlying weather patterns and physical mechanisms. Warm-wet events are more frequent, driven by a dipole pressure pattern that traps heat and leads to warming and precipitation.
The University of Hong Kong launched its HKU Venture Mentoring Service (VMS), a structured mentorship network affiliated with the Massachusetts Institute of Technology's VMS model. The program aims to provide strategic guidance and long-term support to HKU startups, helping them overcome early-stage challenges.
The brain extracellular space plays a crucial role in molecular diffusion, metabolic waste clearance, and post-blood–brain barrier drug transport. Recent advances have improved ECS characterization, enabling its integration into studies of CNS disease mechanisms, therapeutic design, and regulatory evaluation.
High-temperature biochars create stable conditions for microbial-assisted Cd immobilization, reducing crop contamination risks. Low-temperature biochars improve soil fertility but stimulate microbial activity increasing Cd availability.
Research reveals a cross-seasonal connection between tropical Pacific Ocean warming and Antarctic stratospheric changes, with warming in the tropics leading to weakening of the polar vortex and ozone depletion. The study improves predictions of Southern Hemisphere climate patterns and offers insights into Antarctic ozone variability.
A study by King's College London found that night shift workers with type 2 diabetes face challenges in maintaining a healthy diet and managing their condition. The research revealed limited access to nutritious food options during night shifts, leading to poorer quality nutrition and greater variability in glucose levels.
A new study reveals that the honey bee waggle dance is a dynamic, two-way interaction shaped by its audience, contradicting the traditional view of unidirectional information flow. Researchers manipulated the number of potential observers to test how dancers adjust their behavior based on the availability of appropriately aged bees.
The University of Hong Kong secured 46 awards at the International Exhibition of Inventions in Geneva, showcasing its research and innovation excellence across various fields. The university's diverse portfolio highlights its strategic focus on driving cross-disciplinary research and innovation.
A new national study highlights the genetic changes that link exposure to Agent Orange to myelodysplastic syndromes, a group of bone marrow cancers that can progress to acute leukemia. The research found that exposed veterans were diagnosed at a younger age and had a higher rate of disease progression compared to unexposed patients.
Researchers equipped immune cells with proteins to recognize cancer cell metabolism, enhancing their ability to infiltrate and control tumor growth. The new therapy approach shows promise in treating solid tumors, overcoming a key limitation of existing immunotherapies.
Eating ultra-processed foods is associated with slower embryo growth, smaller yolk sacs, and increased subfertility risk. Reducing UPF consumption around conception and pregnancy may improve fertility outcomes for both parents and embryos.
A new study reveals that Australia's national park expansion has not effectively protected threatened species and ecosystems. Despite doubling the size of protected areas since 2010, critical conservation priorities are being overlooked.
Researchers found that the 40,000-year obliquity cycle influenced ocean productivity in subtropical latitudes about 34 million years ago. The study used chemical signals preserved in ocean sediment to reconstruct past biological productivity and showed a strong influence of the Antarctic ice sheet on subtropical marine ecosystems.
Researchers have developed tiny sensors capable of detecting multiple biomarkers simultaneously, including temperature and chemical changes. These sensors have the potential to revolutionize cancer diagnosis and monitoring by providing reliable and clear information about disease presence in a minimally invasive way.
A new satellite-driven model, dEARTH, provides more realistic predictions of sand and dust storm (SDS) severity by accounting for dynamic changes in soil surfaces. The study found that SDS transport is sparse and discontinuous, reducing affected land area by 69% and global transport magnitude by 45%.
A new 4D digital heart model has been shown to improve patient outcomes in cardiac resynchronization therapy (CRT) for heart failure. The model, developed at the University of Calgary, enables personalized pacemaker placement, leading to a 10.8% increase in heart function compared to standard care.
Research shows combining small improvements in sleep, diet quality, and physical activity can significantly reduce major cardiovascular events. Making modest shifts in daily routines, such as sleeping more, eating more vegetables, and exercising more, were associated with a 10% reduction in risk.
A family medicine practice in upstate New York revised its patient dismissal process, shifting from expedited dismissals to a structured review process that prioritizes patient engagement and collaborative planning. This redesign led to a significant decline in behavior-concern referrals and eliminated racial disproportionality.
A systematic review of 31 studies found that diet changes and medications like thiazide diuretics, alkali therapy, and allopurinol may reduce stone recurrence in adults with calcium oxalate or calcium phosphate stones. However, evidence was generally limited, and more research is needed to confirm the effectiveness of these interventions.
The article explores how social media drives donations for Ukrainian military operations, creating a cycle of need for more funding. Former and current military personnel share their experiences, highlighting the desperation and creativity in using available tools to wage war.
Researchers developed a joint display method to analyze patient survey ratings and open-text comments together, revealing patterns between satisfaction scores and patient experiences. This approach provided a fuller view of patient experience than scores alone, with implications for long COVID program evaluations.
A team-based buprenorphine clinic incorporated a trained chaplain into patient care, providing a psychologically safe space for conversation and supporting patients in identifying recovery capital. The clinic reported successful outcomes, with eight patients achieving at least 12 months of sobriety.
Hajo Eicken takes over as AWI Director, bringing extensive expertise in glaciology and a network of national and international collaborations. He aims to strengthen the institute's research by integrating social sciences and indigenous forms of knowledge.
A landmark report by researchers at the University of Reading warns that weak legal rules on AI avatars are preventing UK businesses from accessing their full growth potential. The report proposes four reforms to ensure responsible use of AI avatar technology, including giving people a legal right over their own face and voice.
A cluster randomized controlled trial found integrating social risk alerts improved blood pressure control by increasing screenings for social risks. Intervention clinics showed a modest increase in odds of blood pressure control over time.
A study found that cancer patients during the last phase of life experienced more bleeding events than thromboembolic events. Most patients continued their antithrombotic therapy despite increased bleeding risk, with over 28% experiencing at least one bleeding episode.
A new study by Nirma University reveals that policy synchronization is key to reducing pollution costs in Mediterranean nations. The research found that when a country's environmental taxes, green protection spending, and renewable energy adoption move in perfect synchronization, the overarching cost of pollution drops significantly.
Research found that lonely patients reported worse healthcare experiences, including feeling unheard and unsupported. Patients who felt lonely were also less confident in managing their own health.
A randomized clinical trial found that patients who received community paramedic home care had higher satisfaction rates and preferred future care in a home setting compared to usual care pathways. The study did not show a significant reduction in hospital use or acute care needs, but improved patient outcomes.
A retrospective cohort study in primary care found that patients with floaters or flashes have a higher risk of retinal detachment. The study, published in the Annals of Family Medicine, analyzed data from 1,181 episodes and found that new or recently changed acute floaters were associated with a higher relative risk.
Researchers found shared aging patterns in brain networks between humans and mice, highlighting a framework for studying cognitive aging and improving brain health. The study uses awake mice to examine how complex brain networks change with age, providing a platform for cross-species investigation.
Researchers found that clinicians assess patients in context, developing management plans collaboratively with patients and caregivers. Clinicians also reported growing skills to focus on overall well-being and priorities, suggesting tailored care benefits from team continuity, flexibility, and strong collaboration.
Researchers found that community health centers sustained strong patient-clinician relationships during the pandemic, with higher continuity rates among older adults and those with above-average income. Lower continuity rates were associated with female gender, Hispanic ethnicity, and telehealth use.
A study of 281,582 adults found that those experiencing social and physical isolation were less likely to receive preventive health services. Financial hardship was a significant factor contributing to these findings, with 82.1% of physically isolated individuals experiencing material deprivation.
Researchers examined how practice-based research and learning networks approach data governance, identifying the importance of building knowledge of Indigenous data sovereignty. Existing Indigenous governance frameworks provide guidance on incorporating Indigenous data sovereignty principles into PBRLNs.
A retrospective cohort study in primary care found that patients presenting with floaters or flashes have different risks of retinal detachment. Researchers analyzed data from seven family practices in the Netherlands and discovered a higher absolute risk among episodes with new or recently changed acute floaters, more than 10 floaters...
A comprehensive meta-analysis reveals that biochar functions as a highly active biological regulator, restructuring the earth to boost porosity and moisture retention. Biochar disrupts the soil's nitrogen cycle by suppressing specific enzyme activities, slowing down processes like nitrification and denitrification.
Researchers discovered a new material, boron arsenide, that exhibits record-high coherence of optical phonons due to suppression of three-phonon scattering. This finding holds promise for the development of quantum phononics and could aid in managing excess heat in electronics.
Geisinger Health System uses CCHA and NBS tools to manage complex patient panels, reducing variability in care and prioritizing resource allocation. By focusing on clinical complexity, the system shifted from age-based scheduling to more targeted visit frequency and appointment lengths.
A spatial analysis of 259 Chinese cities shows that digital transformation drives environmental progress by optimizing broader industrial structures. Governments should focus on upgrading entire industrial ecosystems rather than waiting for isolated technological miracles to solve the carbon crisis.
Researchers found that people following a Mediterranean-style diet have higher levels of humanin and SHMOOSE, which are linked to protection against cardiovascular disease and neurodegeneration. The study suggests that specific components of the Mediterranean diet may directly influence mitochondrial biology.
Research from the University of Georgia finds that people with unmet psychological needs are more likely to drink responsibly. Those who don't feel fulfilled are at risk for excessive drinking and related problems.
Researchers created a new method combining scientific tests and artificial intelligence to differentiate recycled plastic from new plastic. The tool, developed by University at Buffalo researchers, can analyze samples and predict the percentage of recycled content with over 97% accuracy.
Researchers found that honey bees change the precision of their waggle dance depending on the size and composition of their audience. The dancers adjust their movements to search for a receptive crowd, resulting in less precise signals when few bees are present.
A new framework, proposed by Professor Zongjie Wang, helps transmission and distribution operations work together to make holistic decisions without centralization. The method combines data from both systems using reduced distribution network models and AI-powered modeling to account for uncertainties and complexities.
Researchers found that heavy young adult substance use was associated with poor memory in late midlife. The study highlights the importance of early interventions to support cognitive health.
Researchers used functional magnetic resonance imaging (fMRI) to scan the brains of 82 mice at various stages of aging and found similar changes in both humans and mice. The study suggests that understanding age-related brain decline in mice could lead to new insights into human brain aging.
UL Research Institutes' Chemical Insights will present findings on chemical exposures and health risks, highlighting new methods for faster, more transparent science. The institute aims to protect people and communities through open science, education, and collaboration.
Long COVID affects quality of life with neuropsychiatric issues like cognitive dysfunction, depression, and memory loss, impacting daily tasks and work. The review highlights the need for standardized diagnosis and treatment to address this chronic condition.
A study by Washington University in St. Louis researchers found that diamond dust is not suitable for strategic stratospheric aerosol injection due to its effects on acid rain, ozone layer degradation and human health. The study's results reduce the viability of using a 'diamond shield' to cool the planet.
The American Heart Association has announced its inaugural Health Care by Food award, recognizing a study that explored effective ways to integrate healthy food into clinical care for Native Americans with uncontrolled hypertension. The study provided compelling evidence that culturally tailored, heart-healthy food box interventions ca...
UCLA researchers identified a key protein, E2F3, essential for survival in cancer cells lacking the protective gene RB. Blocking E2F3 effectively halted tumor growth, offering a new strategy for treating aggressive cancers.
Researchers at Adelaide University identified CD47 as a critical mechanism driving glioblastoma growth and spread. The study found that removing or blocking CD47 reduced tumour cell proliferation, migration, and invasion, leading to improved survival times in animal models.
A study by Gabriela Tonietto and colleagues found that unexpectedly gained time feels subjectively longer, leading people to choose longer activities. Participants in the study opted for longer tasks or leisure activities when given extra time, as they perceived it as more abundant.
The European project CGI-Clinics brings AI-powered Cancer Genome Interpreter (CGI) closer to clinical applications, enabling reliable and scalable tumour genome interpretation in precision oncology. The platform leverages machine learning to transform complex genomic data into actionable insights.
A recent study on honey bees' waggle dance reveals that the dance's precision is influenced by audience size and composition. When there are more observers, dancers become less precise, suggesting that the performer adjusts its movements to engage with a larger crowd, ultimately conveying critical information about food sources.
The NSF Energy Storage Engine has received $45 million over three years to advance next-gen battery and energy storage systems. It will focus on safety, cost efficiency, and AI integration in manufacturing.
Research from the University of Washington reveals that warming winters in the Pacific Northwest are leading to more rain-on-snow events, icy crusts, and complex avalanche forecasting. The study's findings suggest that regions like Eastern Washington, Idaho, and Montana may see an increase in avalanche risk due to warmer temperatures.
TOR protein's molecular switch regulator, SEA complex, has been structurally solved by CNIO researcher Lucas Tafur. The study reveals that SEA doesn't regulate TOR in the way previously thought, providing new insights into understanding cancer and disease prevention.
Researchers from the University of Tokyo successfully developed a high-pressure freezing method that reduces CPA concentration to 20-30% and improves cell viability and metabolic activity. The method holds promise for cryopreservation in regenerative medicine research, with potential applications in drug testing and cell transplantation.
Southwest Research Institute's new facility supports pharmaceutical development, bioengineering research, and streamlined clinical supply production. The facility enhances regulatory efficiency, quality systems, and communication between scientists.
A new study found that therapist flourishing is linked to lower client dropout rates, while burnout was not significantly associated. The researchers suggest investing in supporting therapist well-being to improve early retention and reduce inequities in therapy.
PandaClaw automates complex real-time analyses, enabling researchers to discover novel targets and identify new indications through an intuitive natural language interface. The tool accelerates translational medical research by lowering the barrier for biologists to apply AI.
A study from Michigan State University reveals that extreme weather can actually strengthen certain ecosystems, leading to increased productivity and resilience. The researchers found that phytoplankton species, which are crucial for removing carbon dioxide from the air, thrive when temperature fluctuations increase.
A new study found that 10-20% of patients who stopped taking daily HIV medication were able to control the virus on their own, thanks to the interaction between antibodies and T cells. The researchers plan to investigate how to strengthen these immune mechanisms to develop a treatment for everyone.
A new study published in The Lancet Respiratory Medicine found that an early and rapid diagnostic test for sepsis significantly reduced mortality, especially among patients from the most deprived communities. However, the study also showed no difference in the speed of intravenous antibiotic initiation.
A team of astrophysicists offers a new explanation for negative superhumps in cataclysmic variable star systems, proposing an eccentric accretion disk model. This theory explains the prevalence of negative superhumps across a wide range of binary star masses and may also explain positive superhumps in high mass ratio systems.
A Cornell research team studied the integration of MLB's Automated Ball-Strike System (ABS), which uses AI to track pitches in real time. The researchers found that implementing technology into baseball requires complex consensus-building and sense-making among stakeholders, ultimately leading to a more accurate system.
A study found that inflammation markers may signal depression in women with type 2 diabetes, but vary based on depression symptoms and measures. The research suggests a path toward precision mental health by identifying specific inflammatory biomarkers linked to different dimensions of mental health.
A BGU study uses 'soundscape mapping' to quantify the impact of road noise on bird habitats, revealing massive habitat loss and protected areas under threat. The research suggests integrating noise mitigation technologies into environmental planning to protect biodiversity.
Researchers developed a new multimodal model, ColonGPT, that can perceive, describe, locate, and discuss findings in clinically useful language. The study aims to create more integrated clinical co-pilots to help doctors interpret complex scenes faster and provide timely care.
A new survey maps the major tasks in egocentric vision research, including subject understanding, object understanding, environment understanding, and hybrid understanding. The study identifies bottlenecks that limit progress, but also offers a roadmap for next-generation human-centered AI systems.
Researchers at Linköping University found that an existing medication can restore immune cell function in people with HIV. The study showed that the medication blocks type I interferon and restored the function of immune cells, potentially improving health outcomes.
The study reveals that prolonged exposure to microplastics alters key physiological processes in gorgonians, such as respiration, without visible damage to tissues. The changes indicate sublethal effects on metabolic activity, potentially compromising the resilience of Mediterranean gorgonians.
The NASA EDGE mission will help better understand changes to the Earth's surface, creating detailed 3D maps of vegetation and ice formations. This will improve capabilities for assessing pre-fire risk and evaluating post-fire impacts in semi-arid ecosystems.
The study reconstructs phage-viral operational taxonomic units and plasmids, linking them to microbial hosts using Hi-C sequencing. The results show that host community structure and biofilm architecture determine where these elements thrive, influencing nutrient cycling, antibiotic resistance, and biofilm resilience.
A comprehensive protein atlas has been developed to understand the molecular underpinnings of neurodegenerative diseases. By analyzing protein levels, modifications, and interactions across six major diseases, researchers identified alterations unique to and shared between diseases, as well as distinct subtypes within individual diseases.
The fellow aims to co-build workshops and research that identify material limitations to music participation in progressive movements. He will share stories of artists through an album and field recordings, supplementing existing protest songs with new material.
Researchers at Lund University have developed a new blood marker that significantly improves the accuracy of Alzheimer's diagnosis. The study found that combining two biomarkers, p-tau217 and eMTBR-tau243, can identify people with established Alzheimer's disease with an accuracy rate of around 80%. This breakthrough reduces false posit...
Older adults with and without Parkinson's disease have increased brain activity and muscle signals when recovering from balance disturbances. This makes it more difficult for them to recover their balance.
A new biosensor developed at Oak Ridge National Laboratory detects emerging fungal presence on plants at the molecular level, enabling rapid response to crop threats. The sensor identifies fungal outbreaks in near-real time, allowing for faster treatment and study of plant-microbe interactions.
Nations are coming together at the Convention on the Conservation of Migratory Species of Wild Animals (CMS) to address declining population trends and extinction threats among migratory species. The meeting aims to establish conservation policies and protections for over 2,000 species under threat.
The Island Scholarship programme aims to draw more talent to Orkney, supporting population retention and attraction on Scottish islands. Fifteen postgraduate students will have their fees paid in full for specialist MSc courses, with applications now open.
Researchers are developing a comprehensive diagnostic toolkit to detect lymphatic disorders earlier and as part of routine physical exams. The team, led by Dr. Zhenpeng Qin, is working on identifying biomarkers for lymphatic diseases through blood samples.
Researchers at North Carolina State University have identified key components in large language models that ensure safe responses to user queries. They've developed a new technique to improve LLM safety while minimizing the alignment tax, which allows AI systems to provide safe responses without affecting performance.
An international research team led by Heidelberg University scientists discovered that the NAC complex binds to nascent protein building-blocks and initiates protein folding. This process prevents incomplete intermediate products from leading to incorrect folding, a common cause of neurodegenerative diseases.
The São Paulo School of Advanced Science in Obesity will provide graduate students and early career researchers with a two-week training program on obesity research and prevention. The school will feature renowned keynote speakers and cover topics such as epidemiological aspects, genetic nutrition, epigenetics, and emerging preventive ...
The study provides a breakthrough understanding of the immunoregulatory nature of human tissues, revealing that fibroblasts serve as core regulators of structural immunity in the mouth. The findings lay the groundwork for targeted modulation of fibroblast activity to improve health outcomes in fibrosis, cancer, and autoimmunity.
Researchers discovered that mild hypoxia shortly after birth hinders learning and memory into adulthood through altered neuron-to-neuron communication in the hippocampus. The study also found a second protein involved in hypoxia's effects on this channel's functioning, which was restored when targeted.
Research by David Lebel and colleagues found that only half of the relationships between negative emotions and workplace outcomes were harmful during the COVID-19 pandemic. Instead, many showed no effect or even positive effects, highlighting the importance of empathetic leadership in moderating these outcomes.
Stephen P. Christiansen receives Outstanding Humanitarian Service Award from AAPOS for his dedication to quality patient care, education, and research globally. His extensive work in pediatric ophthalmology has improved lives on a global scale, fostering a sense of community and unity.
Researchers found that exercise and aggressive cardiovascular risk reduction improved heart health, but did not produce measurable cognitive benefits over two years in older adults at risk for Alzheimer's disease. The study highlights a critical gap between vascular risk reduction and brain health.
The University of Texas Medical Branch (UTMB) has launched a new track of its Master of Science in Aerospace Medicine program, expanding access to specialized health science education. The 12-month graduate program prepares multidisciplinary specialists to support the rapidly growing aviation and commercial space industries.
A pilot study found that a standardized virtual reality educational experience improved medical students' knowledge and confidence in head and neck anatomy. The VR platform received high ratings for control, sensory immersion, and realism, with low stress and high perceived success reported by participants.
A new study published in JAMA Pediatrics finds that children with obesity but without metabolic complications still face a significantly increased risk of developing type 2 diabetes, high blood pressure, and abnormal blood lipid levels later in life. Treatment can greatly benefit these children, reducing the risk of future diseases.
The Human Frontier Science Program has awarded 117 researchers from 31 nations with 2026 HFSP Research Grants to collaborate on cutting-edge life science research. The grants support interdisciplinary projects across borders, discovering new possibilities and worlds of knowledge.
A collaborative team of researchers from Kyoto University analyzed the net-zero transition in Southeast Asia, finding that a flexible grid paradigm allows vertically integrated utilities to accept natural gas as flexible energy. The study also highlights the need for synchronized changes in energy systems and financial systems to achie...
Researchers developed a 2.4 GHz wireless receiver chip that can withstand up to 500 kGy of radiation, enabling wireless control of robots in ultra-high-radiation environments. The chip's design reduces charge trapping and increases stability under high radiation exposure.
Researchers at the University of Surrey have developed a new way of designing thermoelectric materials using metal-polymer superlattices, which improves performance and reduces environmental impact. The breakthrough could lead to practical energy harvesting solutions for wearable technologies and industrial applications.
Research team identifies two key strategies to address polyolefin environmental challenges: mechanical upcycling and redesign. Upcycling converts waste into high-value products, while redesign enhances production efficiency and material performance.
Researchers found that endometrial microbiota imbalances contribute to recurrent implantation failure, with dimethylglycine supplementation potentially reversing the effects. The study suggests a complex interplay between microbiota, metabolites, and Treg cells in regulating endometrial receptivity.
This study reveals a novel post-translational regulatory mechanism of ABI4, where RBOHD-derived ROS mediate its oxidative modification. The oxidation enhances ABI4's DNA-binding affinity to the RBOHD promoter, promoting further ROS production in a positive feedback loop.
The EULAR recommends a multidisciplinary approach to managing Behçet's syndrome, aiming to prevent irreversible organ damage and maximize quality of life. The updated guidelines prioritize monoclonal TNFi for patients with eye, vascular, or nervous system involvement, promoting earlier recognition and more consistent care.
The study highlights five fundamental questions about ferroptosis that remain unanswered, including the role of iron, initiation sites, and potential therapeutic targets. Resolving these riddles could clarify how ferroptosis contributes to disease and inform the development of new therapies.
Researchers developed a TnpB generation model to generate 100,000 mutant sequences of ISDra2 TnpB, selecting top five for experimental validation. The results showed high editing efficiencies at specific loci with the TnpB-TD mutant exhibiting stronger capabilities and diverse editing outcomes.
Researchers discovered that N6-methyladenosine (m6A) epigenetic modifications in mosquito-borne flaviviruses enhance viral propagation in vertebrates, increasing transmission from animals to mosquitoes. The study found a host-dependent regulatory mechanism involving the stem-loop I structure and the protein G3BP1.
Researchers created a comprehensive mapping of over 1 million cells in normal adult human skin, identifying 45 unique cell types that vary across composition and arrangement. This study brings scientists closer to developing more targeted treatments for skin diseases like eczema and psoriasis.
A team of scientists has developed a technical system for regulating plant disease resistance without obvious fitness costs. They achieved this by identifying and utilizing in-frame AUGs in functional genes, including PI4KIII β1, to specifically regulate resistance gene expression through protein translation reprogramming.
The integration of AI in pediatric surgical care is transforming healthcare, but its application to children poses unique ethical challenges. Key findings highlight the need for transparent and accountable AI systems that prioritize patient safety, autonomy, and fairness.
Researchers developed a nanoparticle-assisted strategy to simplify NMR spectra by removing unwanted signals. This approach uses imidazolium ionic liquid-coated silica nanoparticles to selectively mute certain signals, revealing the components of interest.
The Alternet Summer School will bring together PhD candidates, researchers, and professionals to investigate the relationship between biodiversity and society. Participants will engage with socio-ecological systems thinking and explore pathways for transformative change in multifunctional landscapes.
This review introduces a groundbreaking 'support-metal-microenvironment' framework to understand Pd nanocatalysts. The authors outline a three-tier anti-poisoning strategy to improve catalyst durability, and highlight the need for advanced characterization tools and theoretical modeling.
The European Region is struggling to detect and treat tuberculosis, with 1 in 5 cases going undiagnosed or unreported. Drug-resistant strains are also a major concern, with the region accounting for a disproportionate share of global cases.
A new study has identified a PRRX2+ epithelial cell/SPP1+ macrophage axis that promotes gemcitabine resistance via TGF-β signaling in pancreatic cancer. The study suggests that targeting this cellular communication network may be key to overcoming drug resistance.
Research highlights biodegradable polymers' energy efficiency in recycling, challenging the assumption of composting as the only end-of-life solution. Chemical recycling offers better environmental and economic outcomes, transforming waste into a profitable resource.
Researchers developed a nano-biostimulant (SeG) combining selenium nanoparticles and glutathione to alleviate salt stress effects on soybean growth. SeG triggers metabolic reprogramming via the JA pathway, promoting arbutin secretion and rhizosphere microbiota growth, leading to improved salt tolerance in soybean.
Children with metabolically healthy obesity at treatment initiation have an increased risk of type 2 diabetes, hypertension, and dyslipidemia. Reduction in BMI z score is associated with reduced cardiometabolic risk, suggesting treatment should be recommended for these children as well.
A multicenter randomized clinical trial found no significant differences in cognitive improvement between exercise, intensive pharmacological reduction of cardiovascular risk factors, or both in older adults. The study results challenge current recommendations on lifestyle modifications for dementia prevention.
Researchers have developed a sub-1-volt, reconfigurable Gires–Tournois resonator for full-colour monopixel reflective displays. The platform exhibits robust performance in achieving vivid colour modulation at sub-1-volt operation and enables uniform colour tuning within a single pixel.
Researchers evaluated alignment between large language model responses and human therapist responses in motivational interviewing. The study found that LLMs can generate responses consistent with motivational interviewing principles, but with limitations in coherence and stylistic alignment.
Despite good rainfall improving soils and vegetation, marine ecosystems and wildlife continue to bear the cost of a warming climate. The report found 2,175 species listed as threatened under federal law, with heat stress exceeding thresholds at 79% of reef locations.
A study of expectant parents in three countries found that long working hours and traditional motherhood cultures hinder gender-equal parenting. Expectant couples identified the need for positive, culturally appropriate coparenting programs to build team spirit and support each other.
A team of researchers has developed a novel 3D atlas technology, enabling comprehensive understanding of cell distribution across entire organs or the whole organism. This innovation combines with existing gene expression data to advance disease understanding and create new indicators.
A statewide cohort study found childhood mortality is significantly higher among children bereaved by parental drug overdose, homicide, and suicide. Parental homicide was associated with the highest risk of mortality in children, highlighting the need for research into potential explanations such as family restructuring and mental health.
Researchers found a shift in key cosmic measurement may be due to statistical artefact. Combining CMB and BAO data showed a mild tension that weakens evidence against standard inflationary models.
A new study found that childhood deaths are significantly higher among children who lose a parent to drug overdose, homicide, or suicide compared to the general child population. The research highlights the need for early preventive interventions and bereavement services to improve children's health following parental death.
A study by Cincinnati Children's Hospital Medical Center and the eMERGE network found that sharing genetic disease risk information with patients can be done responsibly, with a 70% success rate. The team shared results with over 24,000 people using various methods, including one-to-one conversations for those with higher-risk findings.
Researchers from NUS developed a boron-catalysed method to transform oxetanes into larger, medicinally relevant 1,3-oxazinanes with selective insertion of two building blocks, carbon and nitrogen units. This approach harnesses frustrated Lewis pair activation to upgrade cheap starting materials into bioactive compounds.
The study identified six sleep health dimensions in young adolescents: irregularity, timing, duration, social jetlag, weekend oversleep, and continuity. Greater irregularity was associated with higher concurrent transdiagnostic mental health symptoms, while shorter duration was linked to increased symptoms at follow-up.
A systematic scoping review found that social media influencer promotion of prescription drugs carries risks of inaccurate or misleading advice. The study emphasizes the need for updated guidelines and digital literacy initiatives to safeguard public health.
Researchers discovered VISTA as a critical immune checkpoint that balances immune activation and inflammation resolution during kidney injury. Administering exogenous VISTA protein shows potent protection against acute kidney injury and its progression to chronic disease.
Multiple sclerosis prevalence more than doubled in England's healthcare system over 30 years, while survival rates increased. Lifestyle factors, including tobacco use and socioeconomic deprivation, were significantly associated with mortality.
Multiple sclerosis (MS) has seen a significant increase in prevalence, with standardised prevalence doubling from 107 per 100,000 people in 2000 to 232 per 100,000 in 2020. The study also found that survival rates improved due to advances in treatments and care, but inequalities persist, particularly in deprived areas.
A new study published in JAMA Network Open reveals that fathers' mental health declines over time after the birth of their child, with increased risk of anxiety and substance abuse diagnoses returning to pre-pregnancy levels. However, depression and stress-related disorders continue to rise by over 30% one year after childbirth.
A new study reveals that invasive pollinators in Chile are fundamentally reshaping native plant-pollinator networks, leading to a 'silent takeover'. The research found that non-native bees like the buff-tailed bumblebee account for more than 70% of recorded interactions, displacing native species and altering ecosystems.
The study compares remaining life expectancy at age 75 for women and men in Sweden and Japan, finding that older Japanese individuals generally have lower mortality than Swedes. However, this difference is primarily observed among those receiving some form of elder care, with Japanese women expected to spend more years in elder care.
A team from Ohio State University has digitally reconstructed three historically Black communities that were fragmented or demolished for freeway construction. The project, known as Ghost Neighborhoods of Columbus, aims to show how urban renewal decisions of the past have a positive impact on future development.
The article analyzes the legal and ethical complexities of explaining AI decisions to patients, highlighting significant hurdles such as interpretability trade-off, automation bias, and literacy barrier. It calls for co-design partnerships, institutional support, and standards for comprehension to bridge this gap.
Researchers developed a machine learning-based approach to accelerate therapeutic discovery for ulcerative colitis. The model identified 22 promising antimicrobial peptides, one of which, LR, showed strong antibacterial activity and low cytotoxicity.
The Shorebird Science and Conservation Collective uses big data to inform conservation efforts by analyzing tracking data from over 3,400 individual birds. The collective brings together data from various organizations to provide actionable information for land managers and decision-makers.
Researchers developed two neural network models predicting human biological age based on blood biochemistry and gut microbiota. The models demonstrated high predictive accuracy and explainability, holding potential for monitoring intervention effects in clinical trials.
A systematic review found consistent evidence that snus causes gum recession, particularly with loose snus. White snus has virtually no studies on its long-term oral health effects, creating a significant knowledge gap.
Researchers use machine learning to characterize recovery processes, predict outcomes, and optimize strategies for restoring critical infrastructure systems. The review highlights the potential of reinforcement learning to identify effective repair sequences.
A new study demonstrates the use of field-portable assays to study caves in near real-time, revealing complex microbial ecosystems and potential health threats. The research found that geography, material, and depth significantly impact microbial populations, with applications for public health and military decision-making.
Research analyzed pre-hire data and disciplinary records of 6,075 officers, finding that certain warning signs predict later misconduct. The study highlights the need for national police hiring standards to improve screening of candidates.
A Korea University study reveals that liver metabolic disease is a key risk factor for heart failure in older adults with atrial fibrillation, with MASLD having the lowest risk and ALD carrying the highest risk. The study highlights the importance of liver health in cardiovascular disease management.
Using data from the TYPHOON survey, scientists examined the nearby spiral galaxy NGC 1365 and achieved resolution sharp enough to separate individual star-forming clouds. The study reveals that the galaxy grew and merged with other galaxies over 12 billion years of cosmic time.
Scientists create precise folding of dye molecules into 'foldamers', leading to increased fluorescence quantum yield and reduced quenching. Stacks of up to 14 units exhibit significant luminescence increase.
A team of researchers has created a clear nail polish that can turn long fingernails into touchscreen-compatible styluses. The polish works through acid-base chemistry, causing the protons to jump between molecules and change the capacitance slightly enough for smartphones to recognize it as a touch.
Researchers tested shirts from four retailers and found all samples exceeded lead limits, posing a risk to young children. Lead exposure can cause behavioral problems, brain damage, and other health issues.
A new study reveals US and UK volunteer fighters in Ukraine experience high levels of mental and physical health difficulties, including PTSD, moral injury, and poor quality of life. Many struggle to access healthcare after deployment, instead relying on fellow volunteers for support.
Researchers found that plants cannot extract water from dry soil due to increased capillary and viscous forces. The plant's own properties are not limited, but rather the soil's ability to release water.
Researchers at the University of St Andrews have confirmed that sperm whales engage in headbutting behavior, using their heads to push and strike objects, including ships. The study, published in Marine Mammal Science, shows that sub-adult whales are involved in this activity, challenging previous hypotheses about its function.
A large-scale study of over 421,000 individuals found no link between psychosocial factors and cancer incidence. However, some psychosocial factors were associated with a higher risk of lung cancer, which decreased after adjusting for known risk factors.
Researchers at Earlham Institute isolated and sequenced genomes from seven uncultured Bodo spp. single cells, revealing three potentially novel species with unique genetic diversity. The study advances the field of single-cell sequencing in protists, shedding light on hidden biodiversity and symbiotic relationships.
Researchers propose a strategy that encourages individuals to adopt a neutral stance, allowing groups to become more responsive, decisions to become easier to reach, and shifts in consensus to happen smoothly. By doing so, neutrality creates valuable breathing space for reassessment, making it easier for a group to change its mind when...