Thorsten Becker, a professor at UT Austin's Jackson School of Geosciences, has been elected to the German Academy of Sciences, Leopoldina, one of the oldest and most prestigious academies in the world. He joins as only three geodynamicists ever elected, recognizing his outstanding contributions to solid Earth system science.
Researchers from Hokkaido University have developed a superacid-resistant BODIPY dye, enabling stable fluorescence in highly acidic conditions. The new dye outperforms conventional BODIPY dyes by maintaining fluorescence for more than a day in extremely acidic environments.
A new study reveals that a more rational fertilization strategy can improve both productivity and quality in albino tea plantations, while preserving the crop's defining commercial trait. The optimized treatments increased yield by 22-29%, raised free amino acid levels, and strengthened soil quality.
A novel neural illumination estimation and editing framework reconstructs coherent 3D light fields from a single view, achieving 17.0% improvement in image fidelity and demonstrating measurable improvements in perceptual realism for next-generation near-eye displays.
Tea plants under nitrogen stress shift from growth- and quality-related compounds to stress-related metabolites, activating a coordinated defense strategy. This finding offers potential molecular targets for breeding tea varieties with improved nitrogen-use efficiency.
A new magnetic measurement system can reproduce the actual operating environment of next-generation power electronics devices by capturing complete M-H loops up to saturation. The system enables quantitative measurements under high-frequency (MHz-band) and high-field conditions, closely matching real device operation.
Researchers identified the most responsible compounds for golden flower white tea's unique aroma, revealing a coordinated chemical transition from fresh to fermented volatiles. The study's findings provide a practical foundation for flavor regulation and process optimization in this novel tea product.
Researchers have developed a novel solar-driven co-upcycling strategy that enables the synergistic valorization of waste polystyrene and elemental sulfur. The approach integrates clean solar energy with the high-value utilization of industrial byproducts, resulting in the conversion of plastic waste into high-value chemicals.
Boston University researchers Alice Cronin-Golomb and Plamen Ch. Ivanov have been recognized as AAAS fellows for their pioneering work on aging diseases and network physiology. Their research focuses on understanding the brain's function in healthy aging and age-related neurodegenerative diseases, such as Parkinson's and Alzheimer's.
Researchers found that clearing intestinal commensal bacteria improves delivery efficiency of various carriers, including polymeric nanoparticles and viral vectors. This study offers a new approach to enhance therapeutic effects in tumor chemotherapy and gene therapy.
Researchers at Adelaide University found that combining spinning cone column distillation with activated carbon remediation reduces smoke taint's impact on wine. The treatment method improved fruit expression and reduced sulfur dioxide levels without affecting sensory perception.
Researchers have discovered a photostriction effect in perovskite crystals that reversibly changes shape when exposed to light. This property makes them 'smart materials' that can be tuned to respond to stimuli, potentially leading to new device designs such as sensors or actuators.
A new study presents a framework combining biochar engineering with artificial intelligence to design next-generation materials tailored for specific pollutants. The work highlights how advanced data-driven approaches can accelerate the development of sustainable water treatment technologies.
Researchers at Hiroshima University developed a new tool to quickly and accurately map fungal gene functions, even for species with no reference genomes. The tool successfully annotated over 96% of protein-coding transcripts, providing high-resolution functional detection in diverse fungal lifestyles.
A new study reveals that biochar nanoparticles directly enter plant tissues and enhance flowering by reshaping carbon allocation and regulating key genes. This discovery provides a new explanation for how biochar improves crop performance beyond its effects on soil fertility.
A new study by Tulane University found that Oregon's hospital financial assistance policy significantly reduced medical debt in collections. The policy was associated with 872-1,180 fewer people per county having medical debt in collections, and increased charity care spending.
Simon Fraser University (SFU) and Queen's University are partnering to design and build a national sovereign, secure and sustainable high-performance supercomputing system. The collaboration aims to strengthen Canada's sovereign AI supercomputing capacity, support industry innovation, and ensure data security.
Researchers found a direct line of communication between the brain's stress centers and decision-making regions, which is disrupted by alcohol. This disruption can lead to unhealthy habits and relapse during recovery from alcohol use disorder.
Researchers developed a compact optical wireless transmitter that combines high data rates with improved energy efficiency. The system uses a 5x5 array of lasers to transmit data in parallel, achieving aggregate data rates of up to 362.7 gigabits per second.
A new study found that biochar can significantly reduce methane emissions from rice paddies when applied at optimal nitrogen levels. However, high nitrogen inputs may actually increase methane emissions, highlighting the need for careful management of fertilizer inputs.
Dr. Roxana Mehran begins a one-year term as president of the American College of Cardiology, leading a global organization with over 60,000 members. She aims to strengthen partnerships and foster growth, opportunity, and impact.
A new study shows that PSMA therapy can delay the need for hormone therapy in prostate cancer patients by an average of 20 months. The therapy is effective in earlier stages of the disease, improving survival and quality of life for approximately two out of three patients.
A novel method testing directly from urine can tell doctors which antibiotic will work in an average of 5.85 hours, reducing the risk of resistance developing and potentially lethal sepsis. The test agrees with reference methods in 96.95% of cases for seven first-line antibiotics.
Dr. Renuka Jain has been appointed as the new chair of the American College of Cardiology Board of Governors, a role that will empower governors and strengthen Chapter foundations. Her priorities include setting up governors for success, strengthening advocacy at state and national levels, and creating leadership pipelines.
Research suggests that cost of living and male job dissatisfaction played a major role in Europe's populist surge. Financial insecurity emerged as the strongest predictor of an anti-elite outlook, increasing the chances of voting populist by 17-20 percentage points.
A new study finds that air pollution alerts issued in China's cities significantly reduce PM2.5 levels and prevent nearly 54,000 premature deaths over a five-year period. The alerts trigger short-term actions to limit pollution, resulting in a 30-40% reduction in acute mortality risk due to PM2.5.
Researchers found that adults with type 2 diabetes who switched from dulaglutide to tirzepatide reported improved emotional responses and a greater quality of life. The study suggests that tirzepatide may offer broader benefits beyond glucose control, improving patients' physical and emotional well-being.
The event provided free blood pressure, glucose, and cholesterol screenings, as well as colorectal cancer risk assessments with take-home test kits. Families also participated in interactive health education activities and received CPR education.
Researchers have identified protein BCL-2 as a critical mechanism driving persistent pulmonary fibrosis, and a potential therapeutic target to reverse the disease. Blocking BCL-2 with targeted therapy promotes lung repair and reduces scarring in preclinical models.
A study published in PNAS found that the brain's social perception is more inclusive when a shared national identity is made salient. The research suggests that this neural flexibility can help bridge divisions and foster harmonious intergroup relations. By emphasizing common identities and shared goals, social cohesion can be improved.
A global research team has identified fluvoxamine as a medication that significantly improves fatigue and quality of life among adults with long COVID. The study found consistent and meaningful benefits from the widely available antidepressant.
Developed by WashU Medicine researchers, the immunotherapy targets specific blood cancers called T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma. Early-phase clinical studies have demonstrated manageable side effects and early success in treating these aggressive blood cancers.
A recent study published in Gait & Posture found that analyzing a person's walk and getting up from a chair can identify elevated depression and anxiety symptoms. The researchers used machine-learning models trained on data from participants' movements combined with information about their mental state, achieving high accuracy rates.
Researchers are analyzing real-world patient data to study the safety and effectiveness of GLP-1 drugs in preventing Alzheimer's. The study aims to determine if these widely available diabetes medications can delay or prevent the onset of Alzheimer's, a complex public health crisis that affects millions worldwide.
A University of Kansas scholar argues that history standards are prone to politicization, which can lead to a lack of understanding of historical events and people. In contrast, states like Kansas and Maine's 'minimalism' approach focuses on high-level concepts and guiding principles rather than specific content recommendations.
A new tool called GraFT enables precise analysis and reconstruction of actin filamentous structures in plant cells. The tool helps understand the dynamics and spatial arrangement of filaments, crucial for cell shaping, stability, and movement.
A study found that olezarsen significantly lowered triglycerides in patients with hypertriglyceridemia, but did not alter non-calcified coronary plaque volume at one year. Researchers suggested that a more substantial impact on both triglycerides and apolipoprotein B may be needed to observe measurable effects on plaque volumes.
Rock art discovered in northwest Arnhem Land reveals up to 14 new images of the Tasmanian tiger, challenging the theory that it became extinct around 3,000 years ago. The artwork, created using red ochre and white pipe clay, provides rare insight into the cultural importance of thylacines in everyday life.
Researchers discovered that even tiny amounts of PFDA cause visible facial changes and increase risk by 10% at low exposure levels. PFDA blocks key enzyme CYP26A1, disrupting retinoic acid metabolism and leading to abnormal facial development.
Early and continuous acoramidis treatment resulted in sustained incremental reductions in all-cause mortality, cardiovascular-related mortality, and first cardiovascular hospitalization. The findings support the importance of early and continuous long-term treatment with acoramidis in transthyretin amyloid cardiomyopathy.
A Mayo Clinic study found that AI-derived heart fat measurement can predict cardiovascular events more accurately when combined with traditional risk assessment approaches. The measurement significantly improved long-term risk prediction, especially among patients at low-risk categories.
A new study reveals that improving surrounding landscape quality can increase bird species survival in forest remnants, with modest increases in nearby tree cover substantially boosting numbers. This contradicts traditional views on habitat fragmentation and highlights the importance of a more hospitable matrix for conservation.
Researchers develop CAR T cells designed to target both cancer cells and supportive cells in the tumor microenvironment, bearing the surface protein uPAR. The new approach shows significant power to fight cancer with limited impact on other healthy tissues and cells.
Researchers at Osaka Metropolitan University identified the tegmentum region as the area where light signals from the eyes and pineal organ are integrated. This integration enables fish to swim up or down based on differences in light wavelength, aiding survival decisions.
Researchers at NIST have developed a new way to package photonic integrated circuits, allowing them to operate in extreme environments. The HCB technique creates an inorganic bond between the optical fiber and the photonic chip, enabling precise alignment and efficient light coupling.
A study found that elevation of artemin could serve as a disease marker and potential therapeutic target for osteoarthritis in cats. The researchers confirmed that TRP channels commonly associated with osteoarthritis pain were expressed and functional in healthy cat DRG neurons, and increased artemin blood concentrations were correlate...
A new study found that over 40% of children who experienced peer victimization showed clinically significant trauma symptoms. Researchers tracked 250 students' experiences with peer victimization and found that trauma-related symptoms persisted for more than six months.
Researchers developed a perovskite-type ceramic catalyst that maximizes ethanol-to-hydrogen conversion through exsolution of nickel nanoparticles. The study demonstrated the importance of calcination temperature in controlling catalyst performance.
A new study found that modern genetic testing can identify clinically significant genetic explanations for schizophrenia in about 6% of patients, or roughly 1 in 16 individuals. Early age of onset and co-occurring neurodevelopmental disorders are associated with a higher likelihood of finding a genetic explanation.
A large-scale computational study found that point-of-origin effects significantly influence protein diversification, with relatively small divergence seen from ancestral proteins. The research reinforces existing theories on initial protein formation and highlights the limitations of modern AI protein design methods.
A new AI-based system analyzing blood vessels at the back of the eye has been shown to identify people at risk of heart problems with strong correlation. The system, called CLAiR, received Breakthrough Device designation and demonstrates promise as a noninvasive screening method.
Researchers at UMass Amherst have made a breakthrough in shrinking the size of quantum computers by integrating laser systems onto photonic chips. This technology has the potential to enable large-scale quantum computing and make optical clocks portable, with applications in fields such as deep space navigation and GPS.
A recent study found that discontinuing beta-blockers in stable, low-risk patients who have had a heart attack is non-inferior to continuing them. The results suggest that lifelong beta-blockers may be unnecessary for some patients. Discontinuation was associated with similar outcomes and quality of life compared to continued therapy.
Researchers have developed copper-loaded starch nanoparticles that can be broken down by specific bacteria to release antibacterial copper molecules. These nanoparticles were effective against Staphylococcus aureus and Bacillus subtilis, with improved targeting capabilities compared to previous studies.
A team of researchers has created a 3D model of pediatric brain tumors using biopsy-derived organoids, allowing for more accurate testing of new drugs. The model, which accurately reproduces the human environment, preserves the molecular characteristics of the original tumor and maintains cellular heterogeneity.
Researchers have developed a highly sensitive electronic 'skin' using tiny devices that can measure force applied over an area. This technology has the potential to improve prosthetic limbs and robotic manipulation, allowing robots to accurately track hand movements and grasp delicate objects.
Researchers found a 38% higher risk of diabetes in adults with HIV who switched from protease inhibitors to integrase inhibitors. The study suggests that medication changes may have adverse metabolic impacts, warranting close monitoring, regardless of weight gain.
Two studies suggest that loneliness is not just a lack of connection, but how people experience those connections, with increased risk of disease and death associated with feelings of lonelier-than-objective isolation. Daily life perceptions of social threat also contribute to self-reinforcing sequences of emotional states, behaviors, ...
A study reveals dermcidin, a human body natural molecule, exhibits antiviral activity against the influenza virus. Higher baseline levels of dermcidin in individuals who don't develop flu-like symptoms may be associated with lower susceptibility to infection.
Researchers found that the ICM's mathematical predictions are due to a flaw in standardization and lack of evidence supporting inhibitory growth processes. The model was applied to non-sequential traits, contradicting its sequence-based development claim.
Researchers at University of Michigan Engineering and Michigan Medicine used protein nanoparticles to genetically modify several types of human cells, including liver cancer and immune cells. The goal is to develop a safer method for delivering gene therapies without using modified viruses.
Frangopol and his team develop a framework to optimize seismic retrofit strategies for deteriorating bridge columns, balancing risk and cost. The approach integrates time-dependent risk assessment, economic evaluation, and real options analysis to identify optimal intervention timing under uncertainty.
NRG Oncology has appointed Dr. John Nakayama as Vice Chair of the NRG Ancillary Projects Committee, Dr. Ibrahim Nassour as Vice Chair of the Surgical Oncology Committee, and Dr. Scott Okuno as Vice Chair of the Sarcoma Subcommittee. Dr. Angeles Alvarez Secord was also appointed Chair of the Investigator & Career Development Committee.
Researchers from UCSB and UMass Amherst successfully integrated stabilized laser chips with a room temperature trapped ion qubit, enabling compact and portable quantum systems. This breakthrough paves the way for applications in quantum sensing, computing, and fundamental science.
Researchers have designed a system that releases algaecide steadily over weeks or months, making it less expensive and more efficient than existing options. The buoys removed nearly all cyanobacteria without the need for frequent reapplication.
Researchers analyzed 48 isolates of P. griseola and found a potential symbiotic relationship between the fungus and endophytic bacterium Achromobacter xylosoxidans, influencing disease severity. The study sheds light on how the pathogen evolves and may point to new strategies for breeding disease-resistant crops.
Researchers have discovered how a disease-causing bacterium uses a single protein to interfere with the body's defenses in multiple ways, offering a clearer picture of how infections take hold at the cellular level. This discovery highlights the importance of targeting specific interactions between bacterial proteins and human cells in...
A study calls for increased coral assisted evolution research to help reefs cope with rapidly warming oceans. The international team identified nine research priorities, including expanding large-scale field-based research and long-term funding to understand coral biology.
The collaboration aims to improve manufacturing of silicon carbide ceramics, a strong material that can withstand high heat and radiation. Researchers will combine 3D printing and digital technologies to enhance production efficiency and reduce defects.
Researchers have developed a reconfigurable textile interface that supports flat touch, folded 3D manipulation, and shape-change commands. The 'one cloth, many states' framework reduces the need to swap props and recalibrate alignment, making it promising for constrained-space operation training and human-machine interaction scenarios.
Researchers develop ISAMFP, a computational framework that leverages natural target motion to enable super-resolution imaging of dynamic non-cooperative targets. By exploiting angular diversity and phase modulation, the method achieves high-frequency information recovery from sub-aperture intensity measurements.
Researchers have found that targeted ultrasound can aid in unlearning fear more efficiently by stimulating the amygdala, a key region in processing emotions. Participants who received ultrasound stimulation showed reduced fear responses to previously frightening stimuli.
A research team discovered that a protein complex consisting of SMG1, SMG8, and SMG9 ensures the efficient execution of nonsense-mediated mRNA decay (NMD). The study found that this complex is essential for maintaining the stability of NMD under various conditions.
A new systematic review found that screen time use among children and adolescents has dramatically risen over the past three decades, with a clear increase occurring after the onset of the COVID-19 pandemic. The review analyzed 60 peer-reviewed studies and found that older children and adolescents reported higher screen time than young...
A study published by HKUMed found that Resmetirom, a drug approved for treating metabolic dysfunction-associated fatty liver disease, demonstrates potential in preventing and suppressing liver cancer caused by fatty liver disease. The treatment also reduces liver fat, improves metabolic health, and modulates the tumour microenvironment.
Researchers at Tohoku University developed a method to transform regular surfaces into keyboards for AR/MR technology, using the blanching phenomenon to detect fingertip contact. The system requires no special sensors or devices and allows users to rest their fingers on the surface during operation, promoting comfortable interaction.
Scientists have discovered that a fast-rising strep bacterium comes in more forms than expected, with distinct variants linked to specific types of infections. The study provides critical genetic data to improve diagnosis, infection control, and future vaccine planning for this growing bacterial threat.
The new study introduces a comprehensive framework for conducting umbrella reviews in education, providing a structured and accessible guide for researchers. The study's findings highlight the potential of this method to provide high-quality evidence syntheses and strengthen educational research.
Researchers identified a bacterium strongly linked to noma, a deadly disease that affects young children in extreme poverty. Early detection through diagnostic tools could save lives and prevent severe disfigurement.
A study found that dentists have a higher prevalence of vision-related problems due to prolonged exposure to artificial lighting. Chronic dental lighting caused retinal damage, disruption of the blood-retinal barrier, and inflammation, ultimately impairing visual health.
Research in mice reveals direct gene regulation by alcohol metabolites, with varying effects on brain regions and exposure durations. Short-term exposure influences more genes and epigenetic programs compared to lengthy exposure.
Research using high-density EEG recordings found that infant brain activity changes rapidly between 3-6 months, reflecting synaptic connection growth and neural network maturation. This study provides a new method for early diagnosis of neuropsychiatric conditions.
Boehringer Ingelheim and EMFRET Analytics have partnered to advance the GPVI-blocking antibody EMA601 for acute stroke treatment. The substance targets platelet surface receptor glycoprotein VI, blocking thrombosis and inflammation while preserving normal blood coagulation.
The report, prepared by BioAgora, highlights the benefits of building-integrated greenery for biodiversity, climate resilience, energy efficiency, and human wellbeing. It offers actionable guidance for local authorities to integrate green roofs and walls into spatial planning and building codes.
A new policy brief from the University of Bonn and Vodafone Institute highlights Europe's hidden trade deficits with the US and China, which threaten its digital autonomy. The study advises strengthening manufacturing industry competitiveness and reducing dependence on China for digital goods.
Burst stimulation effectively mitigates decline in turning response decay, preserving stable frequency-response relationship and improving closed-loop locomotion control. The proposed navigation system achieves reliable path following with a success rate of 73% and average tracking error of approximately 12 mm.
Family physicians experiencing burnout are more likely to change practices or stop practicing entirely, with 43.5% reporting burnout in a recent study. This can lead to poorer patient outcomes, including increased ER visits and lower care satisfaction.
A global meta-analysis of animal activity found that wildlife shapes landscapes through everyday activities like burrowing and feeding. The study revealed a significant influence on geomorphic processes, with animal activity altering the porosity of soils and sediments by up to 136% in freshwater ecosystems.
The programme aims to nurture youth engagement in marine conservation and strengthen Hong Kong's environmental stewardship by providing hands-on training and empowering students as the next generation of ocean stewards. Students gain experience with advanced research techniques and build leadership and advocacy skills.
A sociologist's research focuses on personal stories behind assisted death decisions, challenging the assumption that choosing death is a rational decision. The study introduces concepts like biographical contraction and closure to understand the complex process of end-of-life choices.
A new study from the University of Oulu suggests that large swings in bedtime could double the risk of serious cardiac events. Inconsistent bedtimes were strongly associated with a higher risk of major cardiovascular events, especially among those who get less than eight hours of sleep.
A new study by UNSW Sydney and published in Carcinogenesis suggests that nicotine-based vapes are likely to cause cancers of the lung and oral cavity. The research, led by Adjunct Professor Bernard Stewart AM, analyzed global research and found consistent findings across multiple disciplines.
Researchers at the University of Bristol found that gentle human interactions trigger positive emotions in young chickens. The study's results suggest that early-life handling can shape animals' affective experiences and improve their welfare.
A study by IBEC reveals how thousands of amylin mutations influence its tendency to form toxic aggregates in the pancreas, linked to type 2 diabetes. The researchers created a mutational map using deep mutational scanning, identifying variations that promote or hinder amyloid formation.
The BD² Integrated Network Longitudinal Cohort Study combines clinical, biological, neuroimaging, and real-world behavioral data to transform understanding of bipolar disorder. The release includes data from 615 participants, covering mood, cognition, brain structure, wearable sensor data, and biological samples.
A new study from Boston University School of Medicine has discovered distinct blood metabolite patterns in centenarians that diverge from typical age trends. The findings suggest unique higher levels of certain primary and secondary bile acids and preserved levels of several steroids, linked to lower death risk. These metabolic signatu...
A new study found that parental academic pressure is linked to four distinct forms of motivational cost: effort, opportunity, psychological, and emotional. These costs are associated with school burnout and academic achievement, but not in the same way.
A team led by LMU physicist Dmitri Efetov has developed a new device capable of directly observing hidden electron interactions in graphene at room temperature. The quantum twisting microscope (QTM) enables continuous, dynamic control of the twist angle, bypassing traditional fabrication constraints.
Researchers discovered that inhibiting tick salivation prevents infection by targeting the tick's nervous system and salivary glands. The study found two distinct signalling pathways controlling saliva secretion, with acetylcholine playing a key role in stimulating salivation.
Researchers discover that azacitidine damages RNA, blocking protein synthesis and triggering the integrated stress response. Cells possess a tolerance to low levels of RNA damage, which determines the effectiveness of chemotherapy.
A recent study using sea slugs identified a cellular mechanism that strengthens long-term memory when exposed to new information at the same time each day. This discovery could provide insights into the most effective learning strategies.
Researchers at the University of Missouri have found that the Amazon molly's ability to reproduce asexually is due to gene conversion, which preserves and repairs DNA inherited from both parent species. This process allows the fish to maintain genetic health despite millennia of cloning.
Researchers discovered that soil bacteria can efficiently degrade toxic chemicals like styrene and phenol through alternative metabolic pathways. The study's findings have significant implications for environmental biotechnology and climate change mitigation.
Researchers developed STM-FPDT to overcome speed bottlenecks in conventional tomographic imaging. The technique enables parallel acquisition of multi-angle information, reducing acquisition time by 4.5-fold and enabling high spatiotemporal resolution observation.
A doctoral thesis confirms that polysaccharides extracted from algae can accelerate wound healing, reduce inflammation and protect skin cells. These natural compounds have potential as alternatives to synthetic treatments for chronic wounds, affecting millions worldwide.
The Gobi-HKU Fund I aims to invest in high-potential HKU spin-off startups, providing capital and strategic support. The fund will focus on AI, robotics, biotech, and other critical sectors, with investments already underway and more support on the horizon.
Children with tympanostomy tubes who swim in treated pools are not at increased risk of ear drainage. In contrast, exposure to untreated or natural bodies of water significantly increases the risk of developing recurrent otorrhea.
The program aims to improve the ability to predict, prevent and treat health complications in people living with Fontan circulation. Clinicians and researchers will generate scientific and clinical insights to develop tools guiding care for patients with Fontan circulation.
A recent study compares two devastating ice avalanches in the Indian Himalayas and Switzerland, revealing drastically different consequences despite similar physical characteristics. Climate change is destabilizing high mountain slopes due to glacier retreat, permafrost thaw, and extreme precipitation, making such hazards more frequent.
Researchers from the University of Tokyo have discovered a link between tropical volcanic eruptions and droughts in Asia. The study found that large eruptions can suppress monsoon convection, leading to reduced precipitation and droughts.
The study demonstrates simultaneous delayed fluorescence and phosphorescence in an organic luminescent material with multiple excited states. It reveals the existence of a second triplet state (T₂) and the competition between TADF and phosphorescence.
A new study uses optogenetics to control specific communication pathways in the common marmoset brain, offering a clearer view of complex behavior and brain disorders. This method enables researchers to manipulate individual long-range brain circuits with greater precision than before.
Scientists have discovered genetic pathways and compounds that protect cone photoreceptors, crucial for central vision, from degeneration associated with age-related macular degeneration. The study used human retinal organoids and identified two kinase inhibitors as key protective mechanisms.
A new study introduces CoPISA, a high-throughput proteomics workflow that uncovers how drug combinations reshape the soluble proteome. The research team applied CoPISA to two AML drug combinations, revealing conjunctional targeting and vulnerabilities in critical proteins.
Dr. Yangzhi Zhu has been awarded a prestigious Career Development Award from the American Heart Association to support his research in translational biosensing and organ health assessment. The award aims to develop innovative sensing strategies for improving donor organ condition and supporting better clinical care.
Researchers propose a terrain-aware framework for optimizing laser power-beaming networks in lunar permanently shadowed regions. The approach balances coverage, connectivity, and cost constraints to enable sustainable exploration tasks.
Researchers Paolo Sossi and Dan Bower found that the Earth is composed entirely of non-carbonaceous material, originating from the inner Solar System. This conclusion contradicts previous theories suggesting a significant contribution from the outer Solar System.
A new model of brain wiring could shorten the path to developing medicines for multiple sclerosis and other degenerative brain diseases. The model, made of a water-filled gel, replicates the physical properties of human axons and has been successfully grown from human cells in the laboratory.
Researchers discovered imported aromatic substances from Africa or Asia in Pompeii's incense burners, indicating a far-reaching trade network. The investigation also found evidence of grape products and native plants used in domestic cult practices.
A multicenter study found that red blood cell exchange transfusion significantly improves clinical outcomes for patients hospitalized with severe babesiosis, a potentially life-threatening tick-borne infection. The procedure was associated with substantially lower risk of in-hospital death or readmission.
Researchers at the University of Tartu have identified a new gene, MGRN1, linked to congenital heart malformations in fetuses. The study found that both parents carry a rare recessive variant of the gene, which causes developmental anomalies when inherited from both parents.
A research team at INRS has developed a simple and energy-efficient way to overcome the obstacle of detecting single photons in a sea of unwanted light. By repurposing a classical optical device, they succeeded in reorganizing light in time to highlight the useful photons without destructive amplification.
Researchers integrated topological photonics with nanoimprint lithography (NIL) to create a stable nanolaser. The work demonstrated type-III corner states and robustness against fabrication defects.
A recent article advocates for a risk-based approach to food safety, aiming to enhance sustainability and resilience of food systems. The authors argue that current policies leading to 'zero tolerance' are fueling the discard of safe food due to increasingly sensitive detection methods.
Researchers have discovered evidence of genetic material from high-risk bacterial groups in wastewater treatment plant effluent, highlighting the potential for antibiotic resistance to spread through ecosystems. This finding emphasizes the need for upgrading WWTPs with advanced technologies to protect public health and waterways.
The €30 million ASCEND project aims to accelerate catalyst discovery using Digital Catalysis and thin-film technologies. By combining AI with physical synthesis and stress testing, the project seeks to unlock performance breakthroughs for commercially viable large-scale deployment of green hydrogen and sustainable chemicals.
A study published in Cell Chemical Biology reveals that an impaired transport protein and ceramide buildup can trigger replicative senescence, a state where cells remain alive but no longer divide. Ceramides accumulate inside the endoplasmic reticulum, triggering stress signals that lead to cellular limbo.
Countries are taking different approaches to regulating polygenic embryo testing, which raises new ethical and legal concerns. The technology has expanded from screening for monogenic diseases to assessing complex traits like intelligence and disease risk, but its clinical value is uncertain due to environmental influences.
This study developed a new predictive model to assess chemical risks in cetaceans by considering the freely dissolved concentration of pollutants. The results show that mixed exposure to POPs at current environmental levels poses a low risk of reducing cell viability or inducing apoptosis.
A new microscopy method can distinguish lipid species in living cells using mid-infrared illumination and optoacoustic detection, producing a unique spectral fingerprint. This approach eliminates the need for chemical labels, reducing stress on cells and enabling real-time lipid mapping.
A longitudinal analysis of 42,000 participants found higher bone lead levels associated with significantly increased cardiovascular disease mortality risk. The study highlights the urgent need for strengthened surveillance, regulation, and remediation to reduce the lead-attributable burden worldwide.
A new study uses drone-based hyperspectral imaging to monitor changes in grassland ecosystems under different grazing pressures. The researchers found that biomass declines with increasing grazing intensity, while certain nutrient-related traits increase, suggesting a shift toward more stress-tolerant plant strategies.
A new study led by Krista Varady found that intermittent fasting reduces testosterone levels and improves female hormone levels in women with PCOS. The study tested time-restricted eating and calorie counting methods, showing that intermittent fasting had additional benefits over calorie counting.
The Joule Hive Thermal Battery system can generate and store heat up to 1,800 degrees Celsius using renewable energy sources like solar or wind. The system's thermal energy storage capabilities make it possible for industrial sites to rely on renewable energy sources flexibly.
A new study by researchers at the University of California, Davis found that breathing in common disinfectant chemicals known as QACs can be far more harmful than swallowing them. The study suggests higher health risks for respiratory diseases such as asthma and COPD from airborne exposure to disinfectant sprays and cleaning products.
Research finds that building gypsum powder reduces soil strength when exposed to water, but augments it at low concentrations of sodium sulfate. The study also reveals the impact of dry-wet cycles on soil pores, structure, and resistance.
A collaboration between Karolinska Institutet and Karolinska University Hospital has integrated whole genome sequencing into routine diagnostic investigations for rare diseases. This approach has enabled the diagnosis of a genetic cause in 23% of patients, with diagnoses involving variants in over 1,500 different genes.
Researchers identified NOX-1 as a key molecular target to prolong ketamine's therapeutic benefits. Combining ketamine with NOX-1 inhibitors significantly extended its antidepressant-like effects. K-4, a novel AMPAR modulator, also showed rapid antidepressant effects that persisted for at least 2 weeks.
Researchers found that early pregnancy probiotics containing Clostridium butyricum significantly reduced the recurrence rate of spontaneous preterm delivery, a major cause of neonatal illness and death. The study suggests that probiotic therapy may offer a simple strategy to prevent premature births in women at high risk.
A new framework proposes a Confucius-inspired approach to reimagining higher education, focusing on relational, contextualized, inward-calling, and unified practices. The study revisits foundational philosophy to address societal needs and challenges, highlighting the importance of self-cultivation and social order.
HeapGrasp uses RGB images to analyze object silhouettes and estimate its 3D shape, reducing the need for depth information. The approach achieves high accuracy while minimizing camera movement and execution time.
Researchers identify DNASE1L2 intron retention as a biomarker for TB progression and reveal its role in regulating inflammation. The study shows that upregulation of DNASE1L2-IR promotes host clearance of pathogen DNA, while downregulation weakens this antibacterial defense mechanism.
Researchers have discovered a new biomarker for immunoglobulin A (IgA) nephropathy, which is an autoimmune disease that can lead to kidney failure. Complement pathway proteins, including CFHR1, were found to be overexpressed in patients with IgA nephropathy, suggesting a potential treatment target and diagnostic marker.
The American College of Lifestyle Medicine launches Project Remission, a national digital series highlighting evidence-based strategies to achieve type 2 diabetes remission through lifestyle interventions. The series showcases clinicians, health systems, and patients who demonstrate the potential of lifestyle medicine in treating chron...
Researchers at the University of York have discovered a protein that allows the African trypanosome parasite to evade detection by destroying specific parts of its genetic instructions. This breakthrough provides new vulnerabilities for future treatments and could revolutionize our understanding of infection.
A new study from Okinawa Institute of Science and Technology (OIST) identifies the 'long fuse' that led to the diversification of modern squid and cuttlefish. The research suggests that these animals originated in the deep ocean around 100 million years ago, sparking rapid evolution after a mass extinction event.
A new study proposes that biological differences, including genetic factors, contribute to autism's strong sex bias. Research suggests that females may be biologically buffered against developing autism due to their X chromosome.
A study analyzing over 15,000 Latin American individuals identifies 35 genes significantly associated with autism, showing extensive overlap with previously identified genes in European-ancestry cohorts. The findings support the universal biological foundations of autism and highlight the need for diverse populations to be represented ...
The study identified a previously unknown recessive neurodevelopmental disorder caused by changes in the RNU2-2 gene, affecting thousands of individuals in the US. Symptoms vary widely, including developmental delays, limited speech, and seizures, and may be more common than previously thought.
A new study found that some Arctic regions regain their 'greenness' within a decade of a sudden permafrost collapse, while others can take centuries or more to recover. The difference is directly related to each site's gross primary productivity, allowing scientists to predict how long it will take a specific site to recover after a pe...
Researchers at OHSU have discovered a previously unknown system of internal 'trade winds' that help cells rapidly move essential proteins to the front of the cell. This breakthrough reveals that cells don't rely on random diffusion but instead create targeted streams of fluid to push proteins forward.
Researchers at the University of Rochester have developed a squeezed phonon laser that precisely controls individual particles of vibration or sound, allowing for accurate measurements of gravity and other forces. This technology has the potential to create more accurate, 'unjammable' navigation systems without relying on satellites.
Dr. Roxana Mehran was appointed President of the American College of Cardiology, focusing on innovation, equity, and global collaboration to advance cardiovascular care. She aims to improve heart health for all through partnerships with major organizations.
Research shows that targeted interventions highlighting personal impact on others can alter behavior among partisans. Both Republican and Democratic voters reduced risk-taking when presented with a simple message asking to choose the safer option for themselves and others.
A study by ISGlobal found that areas with high conflict intensity recorded a higher disease burden, including higher TB case rates and mortality. The research highlights the need for control strategies adapted to each territory, incorporating conflict-sensitive approaches into surveillance, prevention, and healthcare systems.
Research by University of Leeds researchers found that thawing permafrost makes it 25-100 times more permeable, releasing large amounts of greenhouse gases. This could lead to a self-reinforcing process, exacerbating climate change.
In 2025, MDPI saw a 12% increase in manuscript submissions while growing its journal portfolio to 500 titles. The publisher invested in new staff members globally, focusing on research integrity and technology, resulting in comprehensive indexing in leading databases. This reflects sustained researcher confidence and MDPI's commitment ...
Canada's health system would bear the burden of medical care in major armed conflicts, and lacks a coordinated command structure and surge capacity. A national framework with three pillars – sustained clinical readiness, dual-use capacity, and formal coordination – is proposed to address this vulnerability.
The new brain–heart clinical practice guideline provides a holistic approach to managing chronic diseases by integrating neurologic and mental health evidence with cardiovascular guidance. The guideline aims to improve the management of patients with concurrent brain and heart diseases, which often co-occur and share similar risk factors.