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Society for Maternal-Fetal Medicine


SMFM reaffirms acetaminophen as first-line medication for treating pain and fever during pregnancy

Acetaminophen remains the recommended medication for treating pain and fever during pregnancy. Recent studies have investigated its potential association with childhood neurobehavioral issues, but significant limitations were found in their study designs. SMFM recommends acetaminophen as a safe treatment option for pregnant patients wh...

SourceSociety for Maternal-Fetal Medicine·JournalPregnancy·TypeLiterature review·DateJun 1, 2026

New research finds state-level abortion restrictions associated with increased maternal deaths

Research found that states with five or more abortion restrictions had higher rates of maternal deaths from any cause, cardiovascular disease, and violence compared to those with fewer restrictions. Abortion is a medically safe procedure, and restricting access to it has real consequences, according to the study.

SourceSociety for Maternal-Fetal Medicine·JournalPregnancy·TypeData/statistical analysis·DateFeb 12, 2026

Novel AI model accurately detects placenta accreta in pregnancy before delivery, new research shows

A novel AI model has been developed to accurately detect placenta accreta spectrum (PAS) in pregnancy, a life-threatening condition often undetected by current screening methods. The model was retrospectively reviewed on 2D obstetric ultrasound images from 113 patients at high risk for PAS and found to be accurate in detecting all cases.

SourceSociety for Maternal-Fetal Medicine·JournalPregnancy·TypeImaging analysis·DateFeb 12, 2026

Baby2Home smartphone app significantly improves mental health for first-time mothers, study finds

A new study found that the Baby2Home smartphone app significantly reduced symptoms of stress, depression, and anxiety in first-time mothers, improving overall health and parenting confidence. The app provided personalized educational information, infant care trackers, and mental health self-management tools.

SourceSociety for Maternal-Fetal Medicine·JournalPregnancy·TypeRandomized controlled/clinical trial·DateFeb 11, 2026

Study: Discontinuing antidepressants in pregnancy nearly doubles risk of mental health emergencies

Patients who stopped taking antidepressant medication during pregnancy had a nearly two-fold higher risk of experiencing mental health emergencies, with peaks in the first and ninth months. Researchers found no difference in prior mental health visits between those who continued or discontinued therapy.

SourceSociety for Maternal-Fetal Medicine·JournalPregnancy·TypeObservational study·DateFeb 11, 2026

SMFM issues new guidance on diagnosing and managing heart failure during pregnancy and postpartum

The Society for Maternal-Fetal Medicine (SMFM) has released new guidance on diagnosing and managing heart failure during pregnancy and postpartum. The guidance highlights the importance of preconception counseling, assembling multidisciplinary care teams, and referring patients to centers with expertise.

SourceSociety for Maternal-Fetal Medicine·JournalPregnancy·TypeSystematic review·DateOct 3, 2025

One of the largest studies of its kind finds early intervention with iron delivered intravenously during pregnancy is a safe and effective treatment for anemia

A new study found that early intervention with iron delivered intravenously during pregnancy is a safe and effective treatment for anemia. The study, which involved over 4,000 participants in India, showed that single dose IV iron preparations can reduce the risk of low birthweight infants and anemia by delivery.

New study reveals pregnant people who deliver large babies are at increased risk of developing diabetes later in life

A new study found that pregnant individuals who give birth to large-for-gestational-age (LGA) babies are at a higher risk of developing prediabetes or Type 2 diabetes 10-14 years after childbirth. Researchers analyzed data from the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study, which revealed a significant association bet...

New research finds single dose of popular antibiotic given during labor significantly reduced risk of maternal death or sepsis in developing countries

A new study found that a single dose of azithromycin given during labor significantly reduced the risk of maternal death or sepsis in women in low- and middle-income countries. The antibiotic was administered to over 29,000 participants in eight sites across Africa, Asia, and Latin America.

New research finds that people who use cannabis early in pregnancy are at increased risk of poor pregnancy outcomes

Research suggests that using cannabis in the first six to 14 weeks of pregnancy is associated with poor fetal growth and an increased risk of developing high blood pressure during pregnancy. The study analyzed urine samples from over 9,200 participants and found a significant link between cannabis use and adverse placental function.

New research finds pregnant people with gestational diabetes at increased risk of a wider range of cardiovascular problems than previously thought

A new study finds that women with a history of gestational diabetes are at greater risk for a range of cardiovascular conditions, including coronary artery disease and heart failure. The research, which analyzed data from 219,330 women, suggests that preventative measures during pregnancy may help prevent cardiovascular disease later i...

New research finds that having a care manager during pregnancy reduces likelihood of delivering a baby prematurely for individuals most at risk

A new study found that pregnant people on Medicaid who received intensive care management had lower preterm birth rates compared to those who did not. This initiative, known as Pregnancy Medical Home (PMH), provided comprehensive care from a team of professionals, including social and economic support.

Women who develop high blood pressure after birth at greater risk of chronic hypertension

A recent study has found that women who develop high blood pressure during and after pregnancy are at a higher risk of developing chronic hypertension. The study, which followed 368 women for six to 18 months after delivery, found that nearly half of the women developed high blood pressure in the first six weeks postpartum.

SourceSociety for Maternal-Fetal Medicine·JournalAmerican Journal of Obstetrics and Gynecology·DateJan 29, 2021

Experts in high-risk pregnancy respond to the published results of the PROLONG trial

The PROLONG trial found that weekly injections of 17-alpha-hydroxyprogesterone caproate do not reduce recurrent preterm birth or neonatal morbidity. In contrast, a previous study showed a 34% reduction in recurrent preterm birth with this medication. The differing results may be attributed to differences in the populations studied.

SourceSociety for Maternal-Fetal Medicine·JournalAmerican Journal of Obstetrics and Gynecology·DateOct 25, 2019

Experts issue new recommendations for the diagnosis & treatment of maternal sepsis

The Society for Maternal-Fetal Medicine has released new guidelines for diagnosing and treating sepsis in pregnancy, emphasizing the importance of early recognition and management. The recommendations are designed to improve care and prevent organ damage caused by sepsis, with a focus on increasing maternal survival rates.

SourceSociety for Maternal-Fetal Medicine·JournalAmerican Journal of Obstetrics and Gynecology·DateApr 8, 2019

Leading organizations in prenatal screening and diagnosis issue new consensus statement on genome se

The International Society for Prenatal Diagnosis, Perinatal Quality Foundation, and Society for Maternal-Fetal Medicine issued a joint position statement on the use of diagnostic genome-wide sequencing for fetal diagnosis. The consensus opinion emphasizes that routine use of genome-wide sequencing as a diagnostic test is not currently ...

SourceSociety for Maternal-Fetal Medicine·JournalPrenatal Diagnosis·DateJan 9, 2018

Leading medical organizations issue recommendations regarding hepatitis C in pregnancy

Leading medical organizations have issued new clinical guidance on hepatitis C in pregnancy, recommending screenings, treatments, and management strategies to minimize the risk of transmission. The guidelines emphasize the importance of vaccination against Hepatitis A and B during pregnancy for HCV-positive women.

SourceSociety for Maternal-Fetal Medicine·JournalAmerican Journal of Obstetrics and Gynecology·DateOct 19, 2017