A rare 200-million-year-old ichthyosaur specimen of the new species Wahlisaurus massarae has been discovered in a UK private collection. This fossil is only the second known example of this species, previously discovered by Dean Lomax in 2016.
The Clinical Pharmacogenetics Implementation Consortium has published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in women with early-stage estrogen receptor-positive breast cancer. The guidelines recommend alternative hormonal therapies based on CYP2D6 genotype, aiming to improve tre...
Researchers discover piRNAs, small RNA molecules that identify and silence foreign genetic sequences in cells. The study sheds light on a basic mechanism affecting fertility in animals.
A widely used parental guidance program has been shown to reduce domestic conflict and boost economic resilience in South Africa's poorest communities. The Sinovuyo Caring Families Programme for Parents and Teens transformed family relationships in severely at risk communities, improving teenagers' safety and family relationships.
A study published in Biological Conservation found that widespread insects are threatened with a decline in species diversity, genetic diversity, and ability to adapt to environmental changes. The research highlights the importance of maintaining genetic diversity through population exchange for common species.
Researchers at UT Southwestern's Simmons Cancer Center have made a historic breakthrough in CAR-T therapy for acute lymphoblastic leukemia (ALL) in children and young adults. Eighty-one percent of patients treated with CAR-T therapy went into remission, offering new hope for those previously untreatable.
Researchers at Harvard Medical School have identified the molecular machinery responsible for precise dopamine release in the brain, challenging current models of dopamine signaling. The study found specialized active release sites that enable fast and spatially precise secretion of dopamine.
A new study suggests that wastewater injection depth is a critical factor in inducing earthquakes. Simulations using an advanced computer model reveal that limiting depth to 500 meters above the basement can reduce seismic energy release by a factor of 2.8.
A comprehensive genetic study reveals that multidrug-resistant malaria parasites emerged and spread aggressively in Cambodia, under-reporting for years. Ongoing genomic surveillance is vital to inform public health malaria control strategies and detect patterns of resistance.
The Berlin Institute of Health (BIH) recognizes Professors Louise Pilote and Rhonda Voskuhl for their pioneering work on sex and gender differences in cardiovascular diseases and multiple sclerosis. Their research focuses on incorporating gender aspects into medical practice.
Researchers found patients and doctors disagree on surgical scarring evaluation 28% of the time, with patients focusing on depth and physicians on coloration and texture. This highlights the need for better assessment methods and improved preoperative counseling.
Researchers have developed a method for mass preparing cellular aggregates called 'hair follicle germs' that may lead to new treatment for hair loss. The therapy involves regenerating hair follicles, the tiny organs that grow and sustain hair, on a large scale.
Researchers recruited 61 PTLDS patients and 26 healthy controls for a comprehensive clinical and laboratory evaluation. They found significant differences in questionnaire results, with PTLDS patients reporting severe fatigue, pain, cognitive complaints, and sleep difficulties.
A new study reveals how basal cell cancer responds to treatment and offers new ideas for controlling this disease. The researchers found that the relative location of a cell within a tumor can have a big effect on its sensitivity to drug treatment.
Researchers from the University of Tokyo have discovered a molecule called progranulin that plays a crucial role in strengthening and eliminating synapses in the brain. This process is essential for developing neural circuits, but genetic or environmental mutations can disrupt it, leading to disorders such as autism and dementia.
A large Finnish cohort study found that the risk of death by suicide among hospitalized patients with depression has decreased by half since 1991. The study tracked 56,826 patients and attributed the decline to various factors, including improved treatment for depression and increased access to psychotherapy.
Researchers from Trinity College Dublin have developed new tools to circumvent the reactivity of cubane, a widely used pharma industry molecule. This breakthrough enables the creation of tailored compounds with improved drug efficacy and reduced side effects.
Young people in care benefit from social media by maintaining healthy birth family relationships and friendships, making new connections, and easing transitions. Social media provides emotional support, increased self-esteem, and mental well-being, helping reduce stigma and shame associated with being in care.
Scientists at the University of Waterloo have captured the first images of ultrafast photons that are energy-time entangled, enabling direct applications for quantum cryptography and communication protocols. This technique will allow for establishing highly secure communication channels over long distances.
Researchers have developed 'hairy' nanoparticles that can assemble and disassemble on demand, allowing for simultaneous delivery of therapeutic drugs and heating to cancer cells. This technology combines light-sensitive materials with water-repelling yet light-absorbing materials to create photo-responsive gold nanoparticles.
A new study by the University of Bristol found that Oklahoma's seismicity is strongly linked to fluid injection depth. The team used a powerful computer model to examine the connections between injection volume, depth, and location, as well as geological features.
A new supplement in Pediatrics synthesizes research on congenital Zika syndrome, exploring prevention, development profiles, and family support. It highlights the need for accurate information, active surveillance, and formal support services to address the ongoing health impact of Zika virus.
A study published by NYU Steinhardt School finds that all children with disabilities experience violence from birth in West Africa. Violence begins as soon as children are born, and varies depending on the type of impairment.
A new study by the University of Sheffield found that adults with acute lymphoblastic leukaemia living in deprived areas have a 15-20% higher risk of dying. Hospitals treating small numbers of leukaemia cases also have significantly lower survival rates.
A study by the University of Sheffield found China has more football statues than any nation apart from the UK and boasts the world's largest football statue. The design and location of these statues reflect China's failure to join football's top nations and its future ambitions.
Researchers found that 14 out of 16 satellite galaxies of Centaurus A orbit in a single plane and rotate coherently. This synchronized movement contradicts standard cosmology simulations, suggesting flaws in current theories of galaxy formation.
A new study from the University of Missouri found that Instagram users are drawn to social news and entertainment content, but less likely to engage with political or controversial images. Researchers identified strategies for increasing engagement with audiences, including presenting news images in aesthetically pleasing ways.
Researchers have developed a method to selectively mark multipotent stromal cells in mice using the CD73 gene, allowing for the analysis of their distribution pattern and function in living organisms. This breakthrough enables the study of these stem cells in their original state, providing insights into their role in regenerative medi...
A new study found that geese reduce their metabolic rate to cope with winter by lowering their heart rate and body temperature. By doing so, they can conserve energy in the harsh cold conditions.
The study's findings highlight the importance of radio channel characteristics in optimizing smart agricultural sensor network performance. By analyzing these characteristics, researchers can minimize interference and increase system capacity.
Researchers develop MARIO, a fluorescent probe that measures magnesium ion concentration, showing its critical role in chromosome condensation. The study provides a new mechanism for chromosome organization and may help understand diseases like cancer.
Researchers have used novel infrared laser techniques to study methane scattering on a nickel surface with full quantum-state resolution. This breakthrough allows for the observation of vibrational energy redistribution during surface scattering, which can be tested by state-of-the-art quantum theories.
A study by Toyohashi University of Technology found that cell membrane components form isolated domains within an artificial lipid bilayer, separated from the surrounding membrane. The findings provide valuable information for understanding membrane protein functions and developing experimental techniques.
New scientific statement highlights potential heart damage from breast cancer treatments and suggests strategies to minimize risks. Lifestyle choices, such as diet and exercise, can also help decrease the risks of developing both diseases.
Scientists analyzed geochemical and isotopic markers to suggest a cosmic impact triggered the disaster, which consumed 10% of the Earth's land surface in fires. The study provides evidence for human cultural shifts and population declines during this period.
PSMA PET/CT detects prostate cancer recurrence earlier than current imaging modalities, enabling more effective salvage radiotherapy. Nearly half of patients with biochemical recurrence show positive results, with lesions often found in bone and perirectal lymph nodes.
Researchers analyzed daily social encounters of 1,450 residents to better understand epidemic growth. They found that age and day-to-day variation play a significant role in shaping these patterns.
Researchers discovered complex patterns of electrical impulses in brain neurons, with repeating rumblings and spikes sustaining activity for hundreds of milliseconds. These findings suggest that neurons may not fire randomly, but rather follow structured rhythms that could influence our understanding of their function.
Researchers at the University of Alberta discovered that injecting a drug called chondroitinase ABC into the spinal cord can enhance recovery in stroke victims. The therapy, combined with rehabilitative training, showed significant improvements in sensorimotor deficits and allowed subjects to perform tasks at pre-stroke levels.
A study of 9500-year-old bone samples found that people from western Norway were genetically similar to those east of the Baltic Sea in Russia, while eastern Scandinavians were more similar to central and western Europe. The discovery highlights multiple waves of migration to Scandinavia.
Agroforestry systems have been shown to significantly increase soil organic carbon stocks, with an average increase of 34% from agriculture to agroforestry. The transition also showed increases in deeper layers, especially when including perennial plants.
A recent study published in the Journal of Epidemiology and Community Health found that people with anxious personalities are more likely to be bitten by dogs. The survey revealed nearly three times the actual number of dog bites as hospital records indicate, suggesting a higher risk for anxious individuals.
Exercising regularly before surgery for lung cancer halves the complication rate afterwards, with a 48% reduction in postoperative complications. Exercise also reduces the length of hospital stay by almost three days, according to a pooled analysis of 13 clinical trials involving 806 participants.
Platelets have been found to act as the immune system's first responders when a virus, bacterium, or allergen enters the bloodstream. They release serotonin, which triggers an inflammatory response in mice with antigen-antibody complexes, leading to septic or anaphylactic shock.
A randomized trial found that induced labor at 39 weeks significantly reduced cesarean birth rates compared to expectant management. Healthy, first-time mothers who underwent elective induction had lower rates of preeclampsia and respiratory support for their newborns.
Researchers have developed a new therapeutic approach to enhance bone healing by delivering additional Jagged-1 protein at the site of injury. In a study published in npj Regenerative Medicine, rodents treated with Jagged-1 showed improvements in skull and femoral bone injuries, unlike BMPs which caused excessive bone growth.
Researchers developed a new self-efficacy scale to assess employees' ability to manage tasks, negative emotions, and interpersonal relationships. The findings show that high self-efficacy in these areas leads to better job performance, reduced counterproductive behavior, and improved well-being.
The discovery suggests that the increase in oxygen in the biosphere triggered the addition of supplementary amino acids to form more functional proteins. The newer amino acids have systematically softer chemistry, making them more reactive and prone to undergo chemical changes.
Physicists at Aalto University found friction in superfluid helium-3 isotopes despite being in laminar motion at zero temperature. The discovery could help understand turbulence in classical fluids and improve aerodynamics, as well as contribute to studying neutron stars.
A genetic study reveals that multidrug-resistant malaria in southeast Asia originated from a single mutation combination in 2008, which spread rapidly across the region before becoming apparent in 2013. The study highlights the need for close monitoring of genetic mutations to mitigate resistance and prevent further outbreaks.
Researchers demonstrated reliable transmission of stable frequency references over 300km fiber optic networks, enabling synchronization of radio telescopes. This technology could benefit astronomy, particularly for the Square Kilometer Array (SKA), allowing scientists to access the frequency standard anywhere.
Researchers Jos Jonkers and Helen Piwnica-Worms receive a grant to investigate how the immune system recognizes breast cancer. They will use imaging mass cytometry and patient-derived models to devise new treatment combinations, accelerating promising therapies to patients.
Researchers have developed a new method to quantify protein-metabolite interactions, discovering hundreds of new interactions and binding sites. The approach has the potential to identify new regulatory mechanisms, enzymes, and metabolic reactions in cells.
Researchers at UCLA have uncovered a gene network that promotes the formation of spinal motor neurons in chicken and mouse embryos. The study sheds light on how embryonic development is orchestrated for motor neuron formation, with implications for stem cell-based therapies to repair or study neurodegenerative diseases.
A new scientific statement highlights the interconnection between cardiovascular disease and breast cancer, emphasizing the need for research and specialized treatment. The American Heart Association emphasizes prevention and modification of cardiac risk factors during and after breast cancer treatment.
Researchers discovered that silk fibers exhibit Anderson localization of light, a phenomenon that enables efficient control of light due to their nano-architecture. This discovery could lead to innovations in medical therapies and biosensing, as well as the creation of synthetic materials with similar properties.
Scientists from Tomsk Polytechnic University have developed a technology to create individual, 3D-printed dosimetry phantoms tailored to each patient's anatomy, enabling more accurate radiotherapy treatment plans. The new phantoms can replicate complex internal structures and take into account implants and pacemakers.
A study of 3,812 retired NFL players found a slightly higher risk of death compared to replacement players, mainly due to amyotrophic lateral sclerosis (ALS). Repeated head trauma in football may lead to chronic traumatic encephalopathy (CTE), a degenerative brain disease.
A new study from Hiroshima University finds that financially literate individuals are less anxious about life in old age, having accumulated more wealth. Having a child and regular exercise also reduce concern about aging.
A genetic study found that house dust mites replaced the traditional Piwi pathway with a new small RNA mechanism to control transposable elements, affecting up to 1.2 billion people worldwide. The discovery provides insights into the evolutionary history of these common indoor pests.
The study reveals that when a crystal is broken along certain directions, atoms reorganize into labyrinthine structures. These structures have potential applications in hydrogen production and chemical reactions, enabling the splitting of water to produce hydrogen.
CNIO researchers have identified a subpopulation of cancer-associated fibroblasts that foster tumour growth and discovered the Saa3 gene as a key player. Eliminating this gene reprograms the cells, losing their pro-tumour properties, opening a new avenue for therapeutic strategies.
The American Heart Association/American Stroke Association has received a $11.1 million gift from the Henrietta B. and Frederick H. Bugher Foundation to fund targeted research in hemorrhagic stroke. The centers will employ precision medicine, data analysis, and core collaborative research to prevent and treat this type of stroke.
Scientists at Yokohama National University developed a photoresponsive molecular switch that enables the control of sol-gel transitions in thermoresponsive polymers. The azobenzene-containing ionic liquid triggers reversible physical property changes upon light irradiation, showing tunable sol and gel states.
A team of astronomers from the University of Basel has found that satellite galaxies around Centaurus A co-rotate within disc-shaped planes, a phenomenon that challenges the standard model of cosmology. This discovery suggests that these systems are not isolated cases but part of a widespread pattern.
A Tel Aviv University study proposes a novel approach to manipulate genes using a self-assembling platform that delivers nucleic acids to distinct cell subsets. The platform shows promise in treating autoimmune diseases and cancer by targeting specific cells and reducing inflammation.
Researchers have discovered a fundamental energy field guiding formation of complex patterns in materials that crystallize, altering current understanding of metal solidification. This finding has the potential to improve casting and welding processes, leading to stronger alloys and improved metallurgical process control.
Researchers have developed a 3D temperature-based model to understand the CGDS film-growing process. The model connects particle impact velocity, energy transformation, and temperature rise in three dimensions, predicting how the average temperature of the particle impact zone will rise and subside.
Researchers at Kyoto University and University of Tokyo have developed a new method for light detection in nuclear magnetic resonance, promising higher sensitivity for MRI. The 'up-convertion' technology converts radio-frequency signals into optical ones using an elastic membrane and optics.
A new study reveals polar bears have higher metabolic rates than previously thought, emphasizing their energy demands and foraging success. As Arctic sea ice declines, polar bears will face reduced access to seal prey and increased travel costs, potentially leading to population decline.
A new study from UT scientists finds that buprenorphine, a drug used to treat opioid addiction, can impair the ability of obese mice to vary their breathing. This discovery may encourage similar studies in humans, who also need to achieve tasks like climbing stairs and respond to challenges such as disease and surgical stress.
The UK government has invested £184 million in doctoral training for science and engineering research over a four-year period. This funding will support students entering training from October 2018 and October 2019, with 41 universities sharing the allocation.
An international team of astronomers has discovered a galactic arrangement where dwarf satellite galaxies orbit the main body in a narrow disk around Centaurus A. This finding contradicts commonly used cosmological models and simulations.
Researchers have found that exposure to ibuprofen during the first three months of fetal development results in a dramatic loss of ovarian germ cells, leading to reduced fertility. Studies suggest that prolonged exposure to ibuprofen may lead to long-term effects on women's fertility.
Researchers have created defect-free ZnO quantum dots with record-long luminescence lifetimes and resistance to chemical and biological environments. The new nanoparticles are biocompatible and safe for human use, offering hope for numerous applications in biology and medicine.
A study published by the American Psychological Association found a strong correlation between belief in conspiracy theories and vaccine skepticism worldwide. The research suggests that conspiracy beliefs can override scientific evidence and lead to negative attitudes towards vaccinations.
A Mount Sinai study found that white adults with mental illness were 50% more likely than blacks to experience delays in care, and 20% more likely to lack sufficient funds for treatments. The researchers suggest that the Great Recession may have contributed to these disparities.
A University of Connecticut study tracked 130 couples over six months and found that when one member commits to losing weight, the chances are good the other partner will lose some weight too. The researchers discovered a significant weight loss ripple effect where couples' weights were interlinked.
Researchers at Oak Ridge National Laboratory have developed a novel method to create supertough renewable plastic with improved manufacturability. Quantum computers are expected to use dramatically less energy than current supercomputers, reducing energy usage by more than one million kilowatt hours.
Researchers at Rice University have created a new type of gas sensor that can monitor microbes' health and activity in soil without disturbing them. The sensor uses genetically engineered microbes to report on their environment and activity, providing valuable data for bioengineers, geobiologists, and other researchers.
A new international study has found a plane of dwarf galaxies orbiting around Centaurus A, challenging a long-held theory that these galaxies are spread out in all directions. The research reveals that spinning pancake-like systems of satellite galaxies are more common than previously thought.
Researchers tracked polar bears during spring hunting season and found their metabolism increased by 1.6 times, with 4 bears losing 10% or more of body mass over 8-11 days
Researchers have discovered a two-dimensional metallic material called MXene that can detect gases at very low concentrations, improving the sensitivity of chemical sensors. This could lead to early diagnosis and treatment of diseases such as ulcers, diabetes, cancer, cirrhosis, multiple sclerosis, and kidney disease.
New research from Binghamton University reveals that interactions between relatively small organisms are crucial to mutualistic relationships in an ecosystem dominated by larger organisms. The study found that a third partner, scale insects, strengthens an ant-plant mutualism, providing vital nutrients and defense against predators.
A landmark study has identified a small stretch of DNA that best predicts long-term kidney transplant success. The HLA locus genetic match between donor and recipient is crucial for predicting transplant survival and potential personalized treatments.
Researchers used human disease pedigrees to identify genetic causes of complex diseases like multiple myeloma, finding two gene regions involved in DNA repair and packaging. This new method demonstrates the potential for pinning down genes contributing to other complex diseases, such as obesity and Alzheimer's.
A University of Houston biomedical engineer has developed a new method to locate the brain's seizure onset zone in record time, reducing hospitalization time from up to 10 days to just one hour. This breakthrough could save patients weeks of treatment and improve their quality of life.
Recent research reveals that even weak Moonlight and aurora-induced light can trigger a rapid migration of Arctic zooplankton to deeper waters. This phenomenon is caused by the animals' extreme sensitivity to light, which can be disrupted by light pollution from vessels or ocean structures.
Scientists at CUNY and Harvard, in partnership with UBS Asset Management, developed a scientific framework for assessing the environmental and social impacts of investments. The framework provides a new calculus for sustainable investing, using scientifically-based metrics to evaluate companies' actions and products.
A new study reveals polar bears have higher metabolic rates than thought, making them struggle to catch enough seals to meet their energy demands. The research found that five of nine adult female polar bears lost body mass due to insufficient fat-rich prey.
A Montana State University ecologist has received a prestigious Swedish professorship to further his research on predator-prey relationships and conservation of Africa's top carnivores. The award allows him to collaborate with experts in molecular ecology and explore how human activities isolate ecosystems.
Research classifies olive varieties by their susceptibility to anthracnose, with Picual variety found to be highly resistant. Almost all Spanish cultivars are classified as susceptible or moderately susceptible, highlighting the need for farmers to choose resistant varieties.
Researchers at Osaka University discovered that Arid5a translocates from the nucleus to the cytoplasm in response to inflammation, regulating IL-6 production. This finding offers potential therapeutic strategies for septic shock and autoimmune diseases.
Tropical Cyclone Cebile was a powerful hurricane in the Southern Indian Ocean when NASA-NOAA's Suomi NPP satellite captured an image of its well-rounded circulation center. The storm had maximum sustained winds of 132 mph, centered near 16.1 degrees south latitude and 76.1 degrees east longitude.
A study published in Science reveals that ultrafine aerosol particles can intensify rainfall in the Amazon region by enhancing cloud formation and thunderstorms. The presence of these nanoparticles, which are too small to play a significant role in polluted areas, has a substantial impact on the hydrologic cycle in the Amazon.
Researchers have sequenced the genomes of 13 wild and domesticated rice species, revealing valuable genetic information for developing new, efficient, and sustainable rice varieties. The newly created genetic resource provides insights into disease resistance genes, which could help reduce pesticide use and ensure reliable rice harvests.
A randomized, double-blind trial showed that adding sodium benzoate to clozapine improved negative symptoms and overall symptoms in patients with refractory schizophrenia. The treatment had no side effects and may provide hope for treating the most difficult-to-treat patients.
Researchers at Washington State University have developed a simple method to generate high-quality hydrogen from water using inexpensive nickel and iron. The technique could be scaled up for large-scale testing and store renewable energy generated by solar and wind sources.
Researchers at the University of Sydney have discovered a 'quantum hack' that improves quantum error correction by up to 400 percent, allowing for more efficient computations. This breakthrough could lead to fewer physical qubits required for basic calculations, making practical quantum computers a reality.
Researchers at UC Riverside have developed methods to detect signals from spintronic components made of low-cost metals and silicon, overcoming a major barrier to wide application. This breakthrough enables the creation of spintronic computers that generate little heat and use relatively minuscule amounts of electricity.
Researchers at the University of Arizona used a novel technique to observe electrons moving through crystals, shedding light on the unique properties of transition metal dichalcogenides. The study revealed that electrons move differently within and across layers, with implications for future processing technologies.
A quality improvement project found that 80% of patients completed advance directives after discussing their wishes with a hospital-based chaplain. Chaplain-facilitated conversations provided patients with peace of mind and reduced family member guilt, as they documented their wishes in a shared document.
A bacterial duo has been identified as a potential contributor to colon cancer risk. Escherichia Coli and Bacteroides fragilis alter the gut microenvironment by depleting mucus and inducing inflammation, facilitating E.coli colonization.
Researchers at Ohio State University have discovered how the most common DNA mutation happens, a phenomenon that allows guanine and thymine bases to change shape and avoid detection by enzymes. This finding provides a foundation for understanding other types of DNA mutations, which are responsible for diseases and normal aging.
Researchers at CU Boulder discovered a mechanism explaining the persistence of asymmetrical stellar clusters surrounding supermassive black holes. This rate suggests that in post-galactic merger periods, orbiting stars could be flung into the black hole and destroyed at a rate of one per year.
Researchers discovered that Arctic ponds can be hotspots for the degradation of dissolved organic carbon (DOC), releasing more carbon into the atmosphere. The study found that these ponds have distinct chemical compositions compared to rivers, and rapid permafrost thaw is adding carbon to them.
The study provides a comprehensive dataset of mammalian traits in the Atlantic Forest, expanding possibilities for zoological and ecological research. The data aims to draw attention to the region's importance and encourage conservation efforts, highlighting the crucial role small mammals play in the ecosystem.
Polymer researchers found that manipulating polypropylene molecules' regularity affects the end product's mechanical properties. They discovered a relationship between isotacticity, degree of crystallinity, and material toughness.
A study by Columbia University researchers found that loss of Rbfox genes disrupts the assembly of the axon initial segment, crucial for neurons to fire action potentials. The team identified the Rbfox-controlled splicing of the Ankyrin-G gene as a key factor in this process.
Nemours has received a grant of $825,000 from the Toy Foundation to develop trauma-informed patient care and play-based interventions. The project aims to reduce traumatic stress in hospitalized children and their families by emphasizing physical and emotional safety through play.