Researchers compared three mRNA-LNP vaccine platforms in human blood samples, revealing differences in mRNA and lipid component stability. The study provides clues for making vaccines more stable and efficient, potentially leading to lower doses and fewer side effects.
Researchers have discovered a gene, Irx5, that enables blood cancer cells to evade treatment by boosting survival protein levels. By activating specific genes using CRISPR activation tool Partita, the team also identified new potential treatment targets for aggressive lymphoma.
Researchers at Olivia Newton-John Cancer Research Institute discovered that reduced BECLIN1 levels weaken the gut's protective barrier, leading to increased susceptibility to inflammation and disease. This finding may help explain why some people are more susceptible to gut inflammation and associated diseases.
Researchers used DNA barcoding to track cancer cells in solid and liquid biopsies, finding that tumour heterogeneity varies widely depending on necrosis and tumour burden. This study suggests that combining both strategies may provide a more accurate representation of the disease.