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University Hospitals Cleveland Medical Center


University Hospitals and Case Western Reserve University School of Medicine Fund Six Research Teams through the 2026 Collaborative Science Pilot Awards

The program supports junior investigators and established researchers, fostering mentorship, scientific innovation, and interdisciplinary collaboration. The funded projects focus on various areas, including neurorestorative cell therapy, eliminating therapy-induced senescent cells, and microbiome-immune-radiation interactome in prostat...

New study from University Hospitals identifies who is most likely to use whole systems traditional Chinese Medicine during IVF

A new study from University Hospitals Cleveland Medical Center found that women with chronic pain conditions or a history of recurrent pregnancy loss were more likely to use Whole Systems Traditional Chinese Medicine during IVF. The study also identified higher-income neighborhoods and prior ART cycles as factors associated with WS-TCM...

Cleveland researchers discover potential new treatment for Parkinson’s disease and other neurodegenerative conditions

Researchers have identified a promising drug to treat neurodegenerative conditions, including Alzheimer's disease and traumatic brain injury. The study found that inhibition of an enzyme called 15-PGDH was potently neuroprotective by restraining the production of reactive oxygen species that damage the brain.

Creative Destruction Lab launches CDL-Cleveland in partnership with University Hospitals and Case Western Reserve University

The CDL Healthcare Delivery stream will support early-stage ventures building technology to reduce costs, improve patient outcomes, and accelerate innovation in real clinical environments. Founders will have access to University Hospitals as a living laboratory, testing their technologies with clinicians and caregivers.

New study finds surgical patients with mental health conditions who receive music therapy are more medically complex

Surgical patients with mental health and/or substance use disorders who receive music therapy have a 41.8% longer length of stay compared to those without music therapy. They also exhibit increased resource-intensive admissions, anxiety, trauma/stress-related disorders, and heart failure.

SourceUniversity Hospitals Cleveland Medical Center·JournalJournal of Integrative and Complementary Medicine·DateMay 18, 2026

University Hospitals sets new standard: First US health system with ISO 9001-certified corporate headquarters and first in Ohio with all hospitals certified

University Hospitals is the first US health system to achieve ISO 9001 certification for its corporate headquarters and the first in Ohio with all hospitals certified. The achievement demonstrates a systemwide commitment to consistency, accountability, and continuous improvement.

Interdisciplinary care is a promising approach for pediatric patients with long-COVID

A new study found that pediatric patients with long-COVID experience a high symptom burden, including sleep disturbance, anxiety, depression, and fatigue. The study describes an interdisciplinary care approach that incorporates integrative medicine, nutrition, and lifestyle modifications to manage symptoms.

SourceUniversity Hospitals Cleveland Medical Center·JournalOpen Forum Infectious Diseases·DateApr 20, 2026

University Hospitals Harrington Heart & Vascular Institute study highlights long term gains in cardiovascular outcomes at UH Portage Medical Center

A new study by University Hospitals Harrington Heart & Vascular Institute highlights the long-term impact of preventive heart and vascular care. The study shows a significant decline in cardiovascular mortality rates after investments in local cardiac care, with notable reductions among older age groups.

New study shows how to protect the brain to prevent depression and cognitive impairment caused by whole brain radiotherapy

A new study published in Redox Biology found that an experimental neuroprotective drug called P7C3-A20 can prevent the negative side effects of whole brain radiotherapy, including memory problems and depression. The drug was shown to reduce oxidative stress and protect nerve cells in mice with WBRT-induced brain damage.

UH study highlights need for conservative approach to unexplained unintentional weight loss evaluation

A recent study from University Hospitals Cleveland Medical Center found that diagnostic abnormalities were no more likely to occur among adults with unintentional weight loss than among comparison patients. In most cases, the weight loss was not linked to a serious underlying condition, with only a .7% overall rate of cancer.

UH Seidman Cancer Researchers: What is the ideal duration of hormone therapy for the treatment of prostate cancer?

Researchers from University Hospitals Seidman Cancer Center found that the optimal duration of hormone therapy for prostate cancer treatment varies by disease risk. For high-risk patients, longer courses of ADT provide diminishing benefits while increasing the risk of non-prostate cancer death.

University Hospitals Seidman Cancer Center researchers develop easy-to-use tool that can identify high- and low-risk metastatic prostate cancer patients earlier

Researchers at UH Seidman Cancer Center have developed a reliable tool to predict early biochemical response in metastatic hormone-sensitive prostate cancer patients. This framework enables clinicians to identify high-risk patients at diagnosis, guide early treatment discussions, and potentially improve patient outcomes.

SourceUniversity Hospitals Cleveland Medical Center·JournalNature Communications·DateJan 8, 2026

Three UH Rainbow Babies & Children’s faculty elected to prestigious American Pediatric Society

Pediatric faculty members Michael Dell, Ross Myers, and Samudragupta Bora were elected to the American Pediatric Society for their exceptional contributions to clinical care, education, and research. The American Pediatric Society is a leading academic pediatric organization that has advanced child health for over 130 years.

New study shows Alzheimer’s disease can be reversed in animal models to achieve full neurological recovery, not just prevented or slowed

Researchers have successfully reversed Alzheimer's disease in animal models by restoring the brain's energy balance, leading to both pathological and functional recovery. The study used preclinical mouse models and human AD brains to show that maintaining proper NAD+ levels can prevent and even reverse the disease.

SourceUniversity Hospitals Cleveland Medical Center·JournalCell Reports Medicine·DateDec 23, 2025

University Hospitals is the first health system in the world to successfully treat patients with the OneRF® trigeminal nerve ablation system

Trigeminal neuralgia is a debilitating condition causing sudden, severe electric shock-like pain in the face. University Hospitals has successfully treated two initial patients with the OneRF Trigeminal Nerve Ablation System, providing complete pain relief without complications. The minimally-invasive procedure uses radiofrequency ener...

University Hospitals Seidman Cancer Center researchers find age should be a consideration in metastatic prostate cancer treatment plans

A new study suggests that chronological age should be considered when creating treatment plans for men with metastatic hormone-sensitive prostate cancer. Older patients are more likely to experience comorbid conditions and die from causes other than prostate cancer.

SourceUniversity Hospitals Cleveland Medical Center·JournalNEJM Evidence·TypeMeta-analysis·DateNov 10, 2025

New study demonstrates how pediatric integrative medicine can be implemented within a large health system

The study found that patients with anxiety preferred non-drug treatments, such as cognitive reframing and breathing techniques. Pediatric integrative medicine services were shown to fill gaps in care for pediatric patients with complex conditions like long-COVID, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, and obesity.

SourceUniversity Hospitals Cleveland Medical Center·JournalGlobal Advances in Integrative Medicine and Health·DateNov 5, 2025

New study led by University Hospitals Connor Whole Health shows chiropractic care associated with reduction in opioid use disorder in patients with low back pain

A new multi-institutional study published in Health Science Reports found that adults with newly diagnosed low back pain who received spinal manipulative therapy administered by a chiropractor were significantly less likely to be diagnosed with opioid use disorder over a two-year follow-up compared to those prescribed ibuprofen. The st...

SourceUniversity Hospitals Cleveland Medical Center·JournalHealth Science Reports·DateOct 3, 2025

Large study from University Hospitals Connor Whole Health finds certain music therapy interventions may be more beneficial for pain

A large study from University Hospitals Connor Whole Health found that recreative and music-assisted relaxation/imagery interventions were 37% and 48% more likely to reduce pain intensity than receptive only interventions. Longer sessions and explicit pain management goals also contributed to increased pain reduction.

UH Rainbow’s Dr. Charles Macias and the Improving Pediatric Sepsis Outcomes Collaborative honored with John M. Eisenberg Award

The Improving Pediatric Sepsis Outcomes Collaborative has received the prestigious John M. Eisenberg Award, recognizing outstanding leadership and innovation in reducing pediatric sepsis mortality. The award highlights programs demonstrating impact, innovation, sustainability, replicability, and data-driven success.

Pilot study provides foundation for understanding how music therapy improves pain after pancreatic surgery

A new pilot study from University Hospitals Cleveland Medical Center found that music therapy improved pain after pancreatic surgery, supporting its feasibility and acceptability. The study also suggests continued use of music-assisted relaxation recordings over the course of hospitalization to further reduce post-operative symptoms.

SourceUniversity Hospitals Cleveland Medical Center·JournalGlobal Advances in Integrative Medicine and Health·DateAug 20, 2025

Researchers at university hospitals and the Cleveland VA say long-term exercise programs may restore neural connections in Parkinson’s patients

Researchers found measurable changes in brain signals responsible for motor control and movement after 12 dynamic cycling sessions. The study suggests long-term exercise programs could have wider restorative effects on the brain signals of Parkinson's Disease patients.

SourceUniversity Hospitals Cleveland Medical Center·JournalClinical Neurophysiology·DateJul 30, 2025

University Hospitals, Case Western Reserve University and Siemens Healthineers celebrate 40-plus years in radiology innovation celebrate 40-plus years in radiology innovation

The tripartite agreement has driven $100M in NIH funding, 217 invention disclosures, 136 U.S. patents, and 31 international patents, accelerating MRI technology adoption and improving patient care. Technologies developed through this collaboration have shaped multiple FDA-approved products used worldwide.

University Hospitals Seidman Cancer Center becomes first in the United States to implement Akesis Inc. innovative Galaxy RTI device for patient treatment

The University Hospitals Seidman Cancer Center has become the first in the US to implement Akesis' Galaxy RTI device, advancing Stereotactic Radiosurgery (SRS) with enhanced precision and treatment efficiency. The center will also serve as a research hub for this innovative technology.