A study by the Alliance Foundation Trials shows that combining immunotherapy and chemotherapy before surgery can help more patients with locally advanced non-small cell lung cancer undergo complete cancer resection, improving their long-term health. The treatment also led to high rates of lymph node clearance and successful surgical re...
A multidisciplinary research team has discovered a novel antimicrobial material with impressive potency against various fungal and bacterial pathogens. The sulfur-rich polymer material overcomes previous limitations and shows promise as a low-cost, effective medicine and agrichemical solution.
Researchers used genome editing to inactivate a gene involved in anthocyanin production, resulting in increased accumulation of other flavonoids. This modification did not affect lettuce growth, suggesting a promising strategy for developing cultivars with tailored functional components.
A study by DGIST researchers reveals that the olfactory system is the first to be damaged in Alzheimer's disease due to distinct immune responses in different brain regions. The findings provide new insights into the early warning signs of dementia and potential diagnostic markers.
Artificial synapses are built from soft, bio-friendly materials that operate like human brain synapses, merging data storage and computing into a single unit. Laboratory prototypes demonstrate immense capabilities, consuming energy on the scale of femtojoules.
A research team at DGIST has developed a wearable sweat sensor using semiconductor fibers that can collect and analyze sweat automatically. The sensor detects various biosignals, including electrolytes and metabolites, without the need for external power sources.
Researchers have developed a new method to detect single micro/nanoparticles and protein binding events using non-linear resonance in a commercial quartz crystal microbalance. The system achieves femtogram-level sensitivity without requiring surface functionalization or nanomaterial integration.
A research team at DGIST has developed a next-generation near-infrared image sensor technology combining quantum dots with two-dimensional semiconductors. The new sensor exhibits high responsivity and detectivity, enabling rapid detection of weak infrared signals in fog or smoke.
Researchers developed bioinspired auxetic triboelectric nanogenerators that resolve mechanical mismatch challenges in flexible sensors. The devices achieve high energy conversion efficiencies and conform to biological tissues with minimal energy loss.
Researchers discovered a way to tune the quantum properties of tiny defects in diamond by stretching or compressing the crystal, enabling next-generation sensors with unprecedented precision. The silicon-vacancy center, a promising building block for quantum devices, responds predictably to mechanical deformation.
An international analysis found that intrauterine administration of human chorionic gonadotropin (hCG) before embryo transfer does not increase pregnancy or live birth rates. The study urges patients and clinicians to rethink the commonly offered IVF add-on, citing concerns about unreliable trial data.
Researchers have developed a simple yet effective ocean-based model that can predict El Niño and La Niña 15 months in advance using only surface temperature and height observations. The model leverages two core climate memories, Wyrtki memory and Hasselmann memory, to achieve forecast skill comparable to more complex models.
A comprehensive analysis of UK suicide data from 2019-2024 found a significant rise in cases involving sodium nitrite poisoning, predominantly affecting Gen Z and Millennials. The study highlights the need for urgent action to restrict access to this preservative and provide antidotes to mitigate its effects.
In an analysis of child and teen fatalities from 2019 to 2024, the average age of young fatal stab victims is now 14, with Black ethnicity individuals being 13 times more likely to be fatally stabbed. Children living in the most deprived areas are 7 times more likely to die of their wounds than those in affluent areas.
A study analyzing Mumsnet posts reveals thousands of women were dismissed and disbelieved about their pain during routine womb examinations. The research highlights five recurring problems in hysteroscopy procedures, including inadequate information, unequal care standards, and inconsistent pain relief.
The book analyzes Jakarta through the lens of post-suburbanization, highlighting how rapid expansion, infrastructure politics, spatial fragmentation, and socio-environmental challenges shape its growth. The volume provides a comprehensive English-language analysis of Jakarta's contemporary urban evolution.
A University of Texas at Arlington researcher is leading a study investigating cardio-sarcopenia, the combined loss of heart and muscle health in aging adults. The grant aims to uncover how heart dysfunction and muscle loss interact and detect biomarkers for earlier intervention.
A study by University of Colorado Anschutz researchers found that structured engagement with Wikipedia improves public access to accurate, high-quality information. The study revamped the AAA Wikipedia page, increasing content, references and credibility.
The upcoming international forum will explore engineered biochar's potential to advance carbon capture and sustainable resource recovery. Recent advances in biochar design, including structural engineering and hybridization with nanomaterials, will be showcased.
A major multi-country study found that WHO-recommended first-line antibiotics for neonatal sepsis are effective in only one quarter of infections in low- and middle-income countries. High levels of antimicrobial resistance were observed, making it challenging to identify consistently effective empirical antibiotic regimens.
A randomized, double-blind, placebo-controlled study found that combining cannabis with opioids did not improve acute pain relief for people with knee arthritis. The study also showed that using the two drugs together increased side effects such as drowsiness and impaired thinking without added pain relief.
A study found that young adults' memories of their drinking habits may not accurately reflect their daily experiences, highlighting the need for new assessment strategies. Real-time measurements of alcohol use disorder symptoms provide more detailed insights than traditional retrospective self-reports.
A new study reveals that patients with stage two or three bowel cancer who received immunotherapy before surgery have remained cancer-free for over three years. The trial found that this treatment approach can provide more durable cancer control compared to traditional post-op chemotherapy.
A study from Rice University reveals that caregivers' relationships play a crucial role in their mental and physical health. Caregivers who are more self-reliant or emotionally distant experience worse health outcomes, but those with higher relationship satisfaction have stronger buffering effects.
Researchers at Saarland University have developed a new class of miniature actuators using ultrathin silicone film-based pumps. The pumps can operate without motors, compressed air, or lubricants and can be switched on and off as needed.
The University of South Florida hosted the second annual Invention Convention Florida, featuring K-12 student inventors who showcased their original solutions and competed for national advancement. Top honors were awarded across grade-level categories, recognizing students for their creativity, impact, and problem-solving.
Dr. Glenda Halliday has been awarded the 2026 Jay Van Andel Award for her pioneering work on Parkinson's and related neurodegenerative disorders, advancing understanding of clinical symptoms and underlying brain changes.
Researchers at University of Miami developed a novel strategy to enhance survival rates of lab-grown baby corals by modifying the alkalinity of growth tiles. By increasing sodium carbonate levels, they observed a fourfold improvement in early-stage coral survival, paving the way for potential coral restoration efforts.
Researchers develop an innovative method for simulating polarization flip in SFQED, a process that has been challenging due to its inherent complexity. The study aims to explore the potential of quantum computers in tackling high-energy phenomena and finding new physics beyond the standard model.
Researchers from Johns Hopkins Medicine have developed mini brain-like structures grown in the lab that could be used to evaluate how patients with Alzheimer's disease respond to certain drugs. The study found that tiny particles secreted by these brain tissues may contain cellular information that could help scientists find new biomar...
The AGA Research Foundation has awarded $2.9 million in research funding to 84 recipients, accelerating breakthroughs in digestive health. The selected researchers will focus on various aspects of digestive diseases, including gastric cancer and inflammatory bowel disease.
Rosa Rademakers' groundbreaking discovery of the C9orf72 hexanucleotide repeat expansion revealed a common genetic origin for ALS and frontotemporal dementia, transforming how scientists study and diagnose these conditions.
Researchers created a new polymer electrode that conforms to the skin, is comfortable, and can pick up ECG signals without gel or adhesives. The technology performed comparably to existing sensors in proof-of-concept testing, showcasing its potential for practical and cost-effective health monitoring applications.
A study by UC San Diego researchers identified CgA-centered stress-response pathways as key drivers of cognitive resilience in individuals with asymptomatic Alzheimer's disease. The findings also introduce a new framework to accelerate the discovery of preventive therapies for Alzheimer's disease.
Hang Yu, a MSU assistant professor, has been awarded the National Science Foundation's CAREER award to study binary neutron stars and create more accurate theoretical models for gravitational wave signals. His work aims to reveal new signatures of these signals and test neutron star physics to accuracy.
A Salk Institute study identifies Fibroblast Growth Factor 1 (FGF1) as the molecular signal that tells the liver when to release fat into the bloodstream, following a precise rhythm timed to the body's internal clock.
A new study from the University of Pennsylvania School of Nursing's Center for Health Outcomes and Policy Research found that nurses' assessments of their staffing adequacy is a more accurate predictor of patient safety on medical surgical units than traditional administrative data. In contrast, objective metrics like RNHPPD proved to ...
The program achieved a definitive genetic diagnosis in nearly half of enrolled children, identifying pathogenic variants across 330 genes. Families received timely diagnoses, allowing accurate genetic counseling and informed reproductive choices, while guiding clinical management and opening access to targeted therapies.
Scientists have traced the origin of massive Atlantic Sargassum blooms to coastal waters near the Gulf of Guinea in West Africa. The study uses physics-based modeling and probabilistic analysis to show that blooms can be tracked back up to two years before they are detected by satellites.
A team at Virginia Tech developed a water-based process to create multilayer bioplastic films that are both high-performing and easier to manufacture. The method avoids toxic solvents and matches current industrial production speeds, making it viable for real-world use.
DraftMarks makes the writing process visible by layering visual cues to indicate AI involvement. The tool helps writers confront their collaboration with AI and make intentional judgment calls.
The Alliance for Clinical Trials in Oncology has several active trials specifically designed to help people with head and neck cancers. Trials include testing high-dose prophylactic gabapentin to prevent opioid use during treatment, as well as immunotherapy with nivolumab and cabozantinib for mucosal melanoma and nasopharyngeal carcino...
A new trial found that proximal hypoglossal nerve stimulation (pHGNS) significantly reduced breathing interruptions during sleep and improved daytime sleepiness without adverse events. The therapy, an FDA-approved alternative to nasal positive airway pressure, was found to be safe and effective in patients with moderate-to-severe obstr...
A phase 2 trial found that all patients with high-risk smoldering multiple myeloma became MRD-negative within two months of CAR T-cell therapy, with sustained MRD-negativity at a median follow-up of 15.3 months. No severe side effects were observed.
Georgia Tech researchers used computer models to reveal how cells physically pull the neural tube closed during early development. The study found that forces generated by cells create a 'purse string' mechanism made of actin, which tightens and draws the tube closed through a synchronized pattern of cell movement.
Researchers found that Tennessee wine buyers are willing to pay more for wines featuring the state's Quality Assurance Program (QAP) label and those sourced from American Viticultural Areas (AVAs). Consumers also prefer higher-alcohol content wines. The study aims to improve the quality of Tennessee wines and promote the industry.
The partnership aims to align payers and providers around a core set of behavioral health quality measures, creating a shared foundation for how care is delivered, evaluated, and improved. NCQA and West Health will test and refine quality measures across diverse care settings and payer environments.
A new three-step synthesis strategy enables simultaneous control over composition and surface facets of high-entropy alloy nanoparticles. Researchers have scaled the process to produce millions of particles across unique compositions, opening a path to discovering next-generation HEA catalysts with high-index facets.
A new study suggests that a low dose of ibuprofen can help alleviate chemo-brain symptoms in cancer patients, but exercise remains the most beneficial intervention. Researchers randomized 86 patients to receive either exercise plus ibuprofen or other treatments and found that exercise significantly improved cognitive function.
Researchers measured mitochondrial function using MRI in 11 cancer survivors, finding slower recovery time signals weaker function, but also a surprising correlation between worse mitochondrial recovery and lower fatigue. The study suggests that subjective experience of fatigue is multidimensional and not solely physical.
Researchers at Cornell University developed a soft robot gripper that can detect the ripeness of strawberries by touch, then gently twist them off their branch or vine. The technology has potential for more resilient and ecological food production.
A new study found that every type of epigenome protein produces a distinct pattern of gene expression, surpassing the on/off switch functionality. This discovery has significant implications for cellular engineering, enabling more dynamic control over cellular behavior and potential applications in biomanufacturing and bioproduction.
Researchers at University of Michigan created a stem cell model that produces a yolk-sac-like structure in a human embryo, mimicking early pregnancy loss. The model uses mechanical signals to guide development and does not require genetic manipulation.
Researchers show math underlying quantum gravity bears resemblance to quantum Hall effect, resolving cosmological constant problem. The Chern-Simons-Kodama state, a proposed ground state of quantum gravity, has a similar topology that keeps the cosmological constant's value stable.
A new study published in the Proceedings of the National Academy of Sciences found a link between elevated serotonin levels and tinnitus behavioral symptoms. The research suggests that clinicians should recognize and validate patient reports of medication-associated increases in tinnitus when prescribing antidepressants like SSRIs.
A new study found that pediatric patients with long-COVID experience a high symptom burden, including sleep disturbance, anxiety, depression, and fatigue. The study describes an interdisciplinary care approach that incorporates integrative medicine, nutrition, and lifestyle modifications to manage symptoms.
The Universitat Jaume I and AICE have established a joint GEA research laboratory to promote joint research and innovation in environmental engineering. The lab aims to foster knowledge transfer, train PhD graduates, and collaborate with companies in the region.
An international research team at the Mainz Microtron MAMI achieved the most precise measurement of hypertriton binding energy to date, revealing it is significantly more strongly bound than earlier experiments suggested. This breakthrough provides new insights into the interaction between hyperons and nucleons.
A global study has developed 15 internationally comparable indicators for climate communication and education, addressing the lack of reliable data on these essential actions. The indicators cover multiple dimensions of climate change mitigation and adaptation efforts.
Researchers from ICTER and the FDA Center for Devices and Radiological Health developed a new method to visualize the entire retina without refocusing. This breakthrough uses adaptive optics optical coherence tomography (AO-OCT) to generate three-dimensional retinal images with cellular resolution.
Researchers have developed a unified mathematical model explaining two types of 'breathing' solitons in ultrafast lasers, overcoming decades-old puzzle. The new framework accurately predicts complex behaviors and reveals underlying mechanisms.
Scientists discovered that deep-water coral ecosystems in the Galápagos region vanished for over 1,000 years due to prolonged La Niña-like conditions. The study found that these ecosystems may be more susceptible to climate change than previously thought, with significant implications for conservation efforts.
A study by the CNIO group has identified a genetic signature in precancerous breast lesions that can predict which ones will evolve into invasive tumours. This discovery could help avoid over-treatment of women diagnosed with ductal carcinoma in situ, a common precancerous lesion.
The discovery of seven millimeter-sized phosphatized fossils from the early Fortunian Kuanchuanpu Formation provides evidence of annelid body fossils from Cambrian Orsten-type fossil localities. The findings suggest that early annelids were polychaetes, supporting the hypothesis that polychaete morphologies were primitive among annelids.
Researchers developed a machine-learning model to predict protease behavior, enabling more precise and effective treatments. The ProSSpeC calculator suggests engineered synthetic proteases that outperform widely used enzymes.
Researchers found that connected natural habitats help maintain beneficial skin microbes that inhibit deadly fungal pathogens in tropical amphibians. Habitat fragmentation weakens these microbial defenses, leading to increased pathogen infection levels.
SourcePenn State·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateApr 20, 2026
Dr. Stuart Orkin has been awarded the Breakthrough Prize in Life Sciences for discovering genetic mechanisms underlying hemoglobin production and developing a therapy using CRISPR/Cas9 technology. The therapy, Casgevy, treats patients with sickle-cell anemia and beta-thalassemia, debilitating blood disorders affecting millions worldwide.
A new review highlights the role of intestinal stem cells (ISCs) and their supportive microenvironment in driving colorectal cancer initiation, therapy resistance, and relapse. Targeting the ISC–cancer stem cell ecosystem offers a promising strategy to develop next-generation precision care for patients.
SourceELSP·JournalAdvanced Cancer Research·TypeLiterature review·DateApr 20, 2026
A new study uses CRISPR technology to edit grapevine DNA, reducing vulnerability to downy mildew while improving water conservation. This breakthrough could lead to climate-resilient crops in Africa, addressing growing challenges in viticulture.
A new study reveals a significant link between obstructive sleep apnea and skeletal muscle quality, indicating an increased risk of muscle deterioration with aging. Researchers found that people with obstructive sleep apnea have lower skeletal muscle density and a higher skeletal muscle index than those without the condition.
The KIR-CAR T cell therapy has shown promising results in a Phase I clinical trial, demonstrating safety and increasing efficacy with higher doses. The treatment targets mesothelin, widely expressed on several solid tumor cancers, and limits side effects through its natural 'on-off' mechanism.
Researchers at TU Wien found that 2D materials are unsuitable for smaller electronic structures due to a tiny gap formed between the material and insulating layer. However, some materials can be combined with stronger bonds to eliminate this issue, potentially revolutionizing miniaturization steps.
Researchers tracked 30 patients with chronic blood cancers over time, finding that those whose disease remained stable had 'steady' blood cells without additional mutations. Conversely, those with progressing diseases developed changes in DNA years before symptoms worsened. This challenges current views on diagnosing patients without t...
The Helmholtz Association has launched a Water Safety and Security Campaign to protect human health and the environment. Two projects, URBAN-LE Solution Lab in Leipzig and SOLVE initiative in the Elbe River basin, focus on urban resilience and river ecosystem recovery through integrated approaches.
Researchers create molecular crystal with reversible color changes spanning from green to orange-red upon mechanical stress or pressure. The material exhibits adaptive intermolecular interactions and structural flexibility, enabling stimulus-responsive luminescence.
This review highlights the key findings of laser additive manufacturing of metallic lattice structures, including TPMS architectures, node reinforcement, and machine learning-driven optimization. The study demonstrates enhanced mechanical performance, energy absorption, and multifunctional capabilities such as thermal management and vi...
Compass combines Dimensions citation data and Altmetric attention metrics in a single platform, providing real-time publication intelligence. This solution addresses the fragmented data challenge faced by medical affairs teams, enabling them to make informed strategic decisions and communicate impact more effectively.
The report highlights rapid growth of solid-state implementation since SKKU's first successful realization in 2012, with China, US, and South Korea leading global research efforts. Sungkyunkwan University demonstrates world-class research competitiveness, ranking highly in key indicators.
A new AI framework combines digital pathology and structured clinical data to predict PIK3CA mutation status in breast cancer. The Multimodal PIK3CA Model outperformed single-modality models, achieving an AUC of 0.745, with strong performance across multiple clinical datasets.
Elif and Alp Tural teach interior designers to consider how spaces affect users every day, emphasizing trauma-informed design and visual accessibility. Their approach aims to create legible and comfortable environments that respond to users' needs.
Researchers discovered that HDAC7 plays a dual role in immune system development and cancer progression. Restoring HDAC7 in cancer cells can slow or stop tumor growth, offering new hope for diagnosis and treatment.
Researchers develop signal-processing method to suppress distortions, achieving 6mm spatial resolution in single-ended Brillouin sensing. This enables early detection of damage or abnormal conditions in aging infrastructure.
Researchers have identified a new geometric marker of the brain ventricles that can predict which patients with idiopathic normal pressure hydrocephalus (iNPH) will benefit from shunt surgery. The study found that a specific geometric feature, asphericity, is strongly associated with better surgical outcomes.
The Nordic Seas Overturning Circulation (NOC) has strengthened while the Atlantic Meridional Overturning Circulation (AMOC) has weakened due to global warming. Models project a slight increase in NOC's density-driven mechanism, which counterintuitively strengthens the northern branch despite AMOC weakening.
Dr. Eric Richards, a professor at BTI, has been awarded a 2026 Guggenheim Fellowship to investigate Daniel MacDougal's pioneering work on ovarial injection experiments in plant genetics. He aims to use archival research and modern DNA sequencing to determine if MacDougal's protocol actually created mutations.
Children who survive severe childhood malaria experience cognitive and academic impairment that persists into adolescence. The correlation highlights the urgent need for better prevention strategies and therapies to minimize lasting effects of the disease.
Astronauts experience difficulty transitioning between Earth and space due to brain predictions about gravity's pull. After prolonged periods in weightlessness, they overcompensate with their hand grip when returning to Earth, but gradually adjust over time.
Researchers at Hokkaido University developed a new method to measure small forces with high precision, discovering light can twist tiny objects sideways. This phenomenon depends on optical helicity, a subtle property of the light's electromagnetic field.
Researchers at NUS have developed a paired protein language model (PPLM) to predict protein interactions, improving accuracy by up to 17% over leading methods. The model has strong performance across multiple tasks and can capture biologically meaningful relationships between proteins.
Researchers review advanced AI algorithms and hardware acceleration techniques to predict material properties, optimize structures, and discover new materials. This review provides crucial guidance for accelerating data-driven materials research and fostering next-generation functional materials development.
Researchers at the University of Houston found that distraction disrupts memory consolidation primarily due to demands on central executive processing. To improve short-term memory, focus attention on a task for a few seconds before switching, and avoid multitasking.
Researchers at Saarland University have developed energy-efficient geometries for elastocaloric cooling elements using 3D printing. The technology uses shape-memory alloys to release heat when stretched and absorb it when released, promising a cleaner alternative to traditional cooling methods.
The American Geriatrics Society has honored 18 leaders in the field of geriatric medicine for their outstanding contributions to high-quality, person-centered care for older adults. These awards recognize individuals who have made significant impacts through education, research, and clinical practice.
Researchers at Ehime University discovered a π-stacked dimer of positively charged antiaromatic molecules stabilized upon stacking, contrary to their inherent instability. The findings suggest that intermolecular stacking can partially attenuate the intrinsic instability characteristic of antiaromatic molecules.
Professors José María Martín-Olalla and Jorge Mira Pérez refute the 2025 study linking Daylight Saving Time to negative health outcomes, citing a critical error in methodology. The original study's conclusions were based on an incorrect calculation of daily readjustments, which resulted in a zero annual cumulative total.
Scientists have demonstrated a reconfigurable photonic circuit implementing wide class of complex unitary transformations via optical manipulation at three layers only. The platform enables flexible access to many co-propagating structured modes, making it suitable for applications in communication, information processing, and simulation.
A new class of electrolytes has been developed that overcomes the bottleneck of water activity in traditional aqueous batteries. The electrolytes work with commonly used zinc salts and achieve exceptional electrochemical performance, including a wide stability window and ultra-long cycling life.
A retrospective study evaluates morphological irregularity parameters in Gamma Knife treatment planning for vestibular schwannoma patients. The analysis revealed strong correlations between these parameters and treatment plan outcomes, suggesting potential improvements in planning strategies.
Insilico's unified AI framework combines disease-specific predictive modeling with rigorous benchmarking to improve target identification accuracy and reliability. The validated system generates actionable intelligence, prioritizing targets with strong potential for successful development.
A new study removes bitter-tasting compounds from flaxseed oil, preserving its health-beneficial fatty acids and extending its shelf life. The approach uses bleaching earth to selectively reduce cyclolinopeptides, resulting in a flavor-stable oil that remains milder for longer.
The study found a concerning trend towards trial consolidation at top-performing sites in the US, with more limited access to clinical trials for lower-volume locations. This may be due to factors such as increased complexity of phase I trials and regulatory burdens.
A recent study identified distinct microbial signatures in the oral cavity and gut that serve as robust biomarkers for early gastric cancer detection. These microbial markers can be detected in saliva or stool samples using machine learning models, achieving an AUROC of 0.87 for saliva-based detection.
A new study reveals that strategically located poplar plantations can improve functional connectivity for forest birds in fragmented agricultural landscapes. The findings suggest that managed forests may contribute to both biomass supply and biodiversity conservation, particularly for species with moderate to high dispersal capacity.
A team of scientists has found that applying pressure to the heavy-fermion ferromagnet Ce5CoGe2 reveals superconductivity above a magnetic quantum critical point, defying typical expectations. The unusual phase diagram suggests that other ingredients beyond magnetic fluctuations may drive superconductivity in this material.
Researchers developed an AI model called Path-IO that uses machine learning to predict responses to immunotherapy for patients with metastatic non-small cell lung cancer. The model accurately stratified patients into high-risk and low-risk groups, with patients in the high-risk group having double the risk of death or disease progression.
Researchers have discovered two therapeutic vulnerabilities in LAR triple-negative breast cancer: ERBB2 mutations and senescence. Targeting these weaknesses with next-generation TKIs and immunotherapy could improve patient outcomes.
A digital single-session intervention (SSI) has been shown to meaningfully improve young people's sense of hope and control over their lives. The tool provides short, accessible and evidence-based psychological support and wellbeing activities, increasing feelings of hope and self-agency while reducing feelings of being out of control.
Researchers found that macrophages from CF patients display a pre-activated inflammatory state and exhibit exaggerated activation of NF-κB signaling. The extracellular matrix also acts as a persistent inflammatory stimulus, driving lung inflammation persistence despite CFTR function restoration.
Researchers developed a universal binder system for combining different ceramic materials or ceramics and metals in a single process, enabling new designs and functionalities. This technology has promising applications in power electronics, sensors, and autonomous vehicles, and will be showcased at the Hannover Messe 2026.
Researchers at VUB and La Monnaie/De Munt have created a world-first shoe using pure mycelium as the sole material, achieving load-bearing capacity without reinforcement. The innovative design showcases the potential of fungal materials in traditional crafts.
Researchers have developed graphene-integrated microtube resonators with a unique lobe structure to improve optical modulation and detection. The design enhances axial mode quantization, allowing for efficient light localization and trapping within specific regions of the tube.
A new study by Bournemouth University found that the brain reacts to emojis in a way similar to seeing real human faces, with neural responses occurring within 145-160 milliseconds. This suggests that emojis can be processed by the brain as meaningful emotional signals during online interaction.
Chemokines regulate immune cell infiltration and local immunity in tumors, and targeting their receptor axis has emerged as a promising therapeutic target in cancer immunotherapy. Chemokine-modulating strategies combining with other immunotherapies have demonstrated considerable synergistic potential.
A new biosensor detects active tuberculosis using a protein secreted by the bacterium, providing more accurate information from a clinical perspective. The device achieves high sensitivity and specificity, with promising potential for resource-poor countries.
The University of Hong Kong launches School of Governance and Policy, convening global thought leaders to address regional and transnational challenges. The inaugural week will feature a dynamic platform for ideas to meet action, bridging academic insight, policymaking, and real-world innovation.
A new study finds that water masses from the Southern Hemisphere have been a major contributor to the Indonesian Throughflow for over 800,000 years. The researchers measured nitrogen isotopes in sediment cores and found a remarkable long-term stability of the nitrogen cycle along the equatorial Pacific.
A recent study by researchers at Griffith University and others found that exposure to cocaine contamination altered the movement patterns of Atlantic salmon in Lake Vättern, Sweden. Fish exposed to benzoylecgonine swam up to 1.9 times farther than unexposed fish, with dispersal distances reaching up to 12.3km.
Researchers have discovered a way to prevent the collaboration between two important cancer-related proteins, N-MYC and Aurora A. This breakthrough could lead to new medications to combat childhood cancer. The study, published in Nature Communications, provides insights into how these proteins interact with each other.
Researchers identify specific chemicals that trigger neural activity in nematodes when they detect certain bacteria, leading to changes in feeding behavior and avoiding harmful pathogens. The study sheds light on fundamental mechanisms of how neurons interact with bacteria, paving the way for potential therapeutic interventions.
A phase II clinical trial found that ciltacabtagene autoleucel, a CAR T-cell therapy, achieved a 100% minimal residual disease (MRD)-negativity rate in patients with high-risk smoldering multiple myeloma. The treatment also showed low-grade cytokine release syndrome and transient hematologic toxicities.
A study of 1,338 older adults found that longer, more frequent, and morning naps were associated with higher mortality rates. Excessive daytime napping was linked to increased risk of neurodegeneration, cardiovascular diseases, and greater morbidity.
A cluster-randomized trial found that an adaptive mobile health intervention effectively reduced the rate of gestational weight gain and total gestational weight gain among pregnant patients with overweight or obesity. The study suggests that technology-based interventions can be a valuable tool in managing excess weight during pregnancy.
A video game developed to improve trauma triage decision making in emergency doctors has shown promising results. The game reduced under-triage rates for older patients by 49% compared to those who did not play the game, suggesting improved diagnostic abilities and adherence to guidelines.
The article discusses how emerging digital tools are capturing the biopsychosocial reality of chronic pain. Digital tools such as wearables, AI-driven trackers, and ecological momentary assessments mitigate recall bias by recording data in real-time, providing a more holistic picture of the patient's journey.
Researchers at Gladstone Institutes identified hundreds of human genes influencing HIV infection and two potent antiviral proteins, PI16 and PPID. These proteins block HIV's entry into T cells or limit its ability to replicate within the cell.
A new study reveals that people with Parkinson's disease have a distinct gut microbiome, as do those at genetic risk but without symptoms. This could lead to early detection and potential prevention strategies.
A new study found that cancer types with high lethality receive lower federal research funding, prioritizing these cancers could help direct resources to diseases with greatest potential to reduce suffering. Additionally, certain cancers have a disproportionate impact on underserved populations and quality-of-life burden.
A new study co-led by UT Health San Antonio found that having three or more live births is associated with a reduced risk of stroke and brain damage in women. The research suggests that reproductive factors, such as the number of live births, may be an important predictive factor in assessing stroke risk in women.
The study reconstructs the genetic profile of a small group of Neanderthals from Stajnia Cave, Poland, providing a coherent genetic picture of Neanderthals in this part of Europe. The discovery sheds light on the distribution of a particular Neanderthal maternal lineage in western Eurasia.
A nationally representative study found nearly 1 in 10 U.S. adults with heavy drinking and obesity conditions, highlighting the need for preventive efforts in younger and middle-aged adults without insurance or Medicaid coverage to curb rising rates of alcohol-associated liver disease deaths.
Researchers found that men with a 'country' identity showed distinct vowel patterns in their pronunciations, different from those living in neighboring areas. Country identity was more robustly linked to language patterns than travel patterns.
Researchers discovered how lycophytes, ancient spore-bearing vascular plants, adapted to survive the Permian-Triassic mass extinction by using carbon acid to store CO2 for daytime photosynthesis. This CAM photosynthesis method helped them thrive in extreme heat and dry environments.
Researchers have mapped the first migratory bird brain using high-resolution light microscopy and open-source software tools, creating a valuable resource for neuroscience worldwide. The new Eurasian blackcap atlas enables consistency in brain data interpretation and fosters collaboration among researchers.
Researchers developed a machine learning model using DNA methylation patterns to predict cancer origin in patients with unknown primary. The model correctly identified the cancer type in about 95% of cases, suggesting it could support personalized treatment decisions.
Manchester scientists discovered a new type of aromatic molecule made entirely of metal atoms, with a tiny ring of three bismuth atoms supporting circulating currents like benzene. The finding bridges the gap between organic and all-metal aromaticity, offering insights into chemical bonding.
Primary care-based discussions on reproductive goals, immunizations, and risk-reducing interventions optimize pregnancy outcomes. Prepregnancy counseling reduces maternal morbidity and mortality, while also promoting healthy fetal development.
A study shows how a kea parrot with a missing upper beak uses innovative fighting techniques to dominate his group and gain social status. He achieves this through 'beak jousting,' which proves more effective than other methods, leading to improved health benefits and social recognition.
A team of physicists has discovered that atomic clocks can probe time in a way that reveals its quantum nature. By manipulating the vacuum itself, they created squeezed states that exhibit subtle quantum behavior, allowing a single clock to measure how it ticks both faster and slower simultaneously.
Researchers developed a pathomics framework using a deep learning survival prediction model that analyzes pathology slide images and study patterns to predict patient outcomes. The model correctly stratified patients into high- and low-risk groups with significantly different outcomes.
Researchers at Keck School of Medicine have identified a new potential treatment target for AARS2-related cardiomyopathy, a rare and fatal heart muscle disease in infants. By targeting the PCBP1 gene, they aim to restore healthier AARS2 function in heart cells and prevent damage.
A genetic analysis of 132 individuals buried in a megalithic tomb near Paris found a sharp reduction in the local population followed by the arrival of new groups from southern France and the Iberian Peninsula. The study detected ancient pathogens, including the plague bacterium Yersinia pestis.
Researchers developed a thin plastic film with ultra-fine structures that tear apart viruses on contact, killing them through mechanical force. The film offers a scalable and practical alternative to existing antiviral coatings.
Researchers at NUS CDE have developed biowaste coatings that improve the conversion of carbon dioxide into useful fuels and chemicals, achieving high selectivity rates and reducing reliance on PFAS. The coatings, made from crustacean shells, insect exoskeletons, and plant matter, offer a cost-effective pathway to climate technology.
A study published in Applied and Environmental Microbiology suggests that a fungus strain called Aspergillus calidoustus can survive the harsh conditions of space travel and Martian environments. The fungus was found to tolerate extreme temperatures, radiation, and pressure, making it a strong candidate for surviving the trip to Mars.
Three European countries reach 90% HPV vaccination coverage among girls by age 15, marking progress in cervical cancer prevention. HPV vaccination programmes show significant reductions in infections and precancerous lesions, with early administration increasing full protective potential.
Researchers developed a heat-tolerant cutinase enzyme that combines structural rigidity with flexibility, enabling efficient degradation of PET at high temperatures. This discovery provides new insights into designing enzymes for sustainable plastic recycling and addresses the pressing issue of plastic waste.
A research team developed a two-electrode-based real-time diagnostic technology capable of precisely analyzing the causes of performance degradation in anion exchange membrane water electrolysis (AEMWE) systems under actual operating conditions. The study reveals that voltage increase in water electrolysis systems arises not only from ...
Researchers have identified the Prrx1 gene as a key regulator of metastatic potential in breast cancer tumors. This discovery helps explain why highly invasive cells do not always give rise to metastases, and how cells combine invasiveness and proliferation to become the most dangerous from a clinical perspective.
Research by Taro Yoshimura examines the history and linguistic landscape of biodiversity, finding that ancient Greek dominates molluscan family names, often due to prestige and style. This highlights a human side to naming, where science is shaped by epistemic values and cultural biases.
A recent study reveals that tiny cave shrimps, specifically the Typhlatya genus, play a crucial role in maintaining the unique food web of anchialine caves in the Yucatan Peninsula. The shrimps convert microbial growth into animal biomass, introducing essential nutrients into the ecosystem.
A landmark study found a significant association between prenatal prescription of sterol biosynthesis-inhibiting medications and the risk of autism spectrum disorder (ASD) in children. The research identified commonly prescribed medications as potential contributors to neurodevelopmental vulnerability.
Researchers from CiQUS introduce a prototype thermal memory device capable of switching between high and low thermal conductivity states through electrical stimuli. The device relies on ultra-thin ferroelectric films with precise regulation of thermal conductivity, enabling stable and non-volatile thermal states.
A team of scientists has developed a new method to assemble luminescent molecules into nanotubes with unusual excitonic properties. The nanotubes can be arranged to form luminescent fibers that reach several centimeters in length, and exhibit multidirectional energy transfer within their interiors.
A Phase II trial found that exercise can improve cognitive function in patients receiving chemotherapy, while low-dose ibuprofen may also have some benefits. The study suggests that exercise is more effective in improving cognitive outcomes, but further research is needed to explore the effects of ibuprofen and combination therapy.
A recent survey found that 72% of youth aged 13-17 use AI companions and 52% report regular use, highlighting the need for robust safeguards. Well-designed chatbots can normalize help-seeking, reduce isolation, and offer coping strategies, but poorly designed ones can cause harm.
Researchers have discovered a novel optical material, arsenic trisulfide (As2S3), that can be permanently modified by light and sculpted at the nanoscale level. This material exhibits an unusually large light-induced refractive-index change, enabling the creation of extremely fine optical fingerprints.
Physicists used a water tank to simulate the Aharonov-Bohm effect, revealing counter-rotating wave patterns that mimic quantum effects. The study showed that adding a vortex causes shifts in wave phase, resulting in rotating lines of zero wave height, or nodal lines.
A national poll suggests that one in three parents report their young adult children are minimally active or inactive, with lack of interest and screen time being major barriers. Parents often try to encourage physical activity through verbal encouragement, activities, and exercising together, but many efforts are not successful.
Researchers developed a computational model that helps identify the origin of complex magnetization reversal in soft magnets, revealing key features such as PC1 and four critical energy barriers. The study offers a general strategy for examining complex energy landscapes in magnetic systems.
A Canadian study found gaps in how physicians were monitored and sanctioned for sex-based misconduct, with complaints often not reported on regulatory websites. The researchers suggest a national registry listing incidents by type and outcomes could help address the issue.
A recent study by Doshisha University found that a supportive classroom environment boosts students' willingness to communicate in English, promoting language learning and motivation. The study applied self-determination theory principles to analyze the factors influencing Japanese university students' communication willingness, highli...
Researchers have developed a new tool called Microbial Interaction and Niche Determination (MIND) that accurately predicts how microbes compete within complex communities. By analyzing nutrient preferences and energy allocation, MIND helps beneficial organisms outcompete dangerous pathogens. This approach has the potential to accelerat...