A new study suggests that the Moon's surface record sets a hard limit on the possibility of late meteorite delivery being the dominant source of Earth's oceans. The researchers analyzed oxygen isotopes in lunar regolith samples, finding that even generous assumptions about impactor flux would only supply a small fraction of Earth's water.
Research led by University of Miami researchers shows that effective fisheries management can coexist with predator recovery, contradicting previous assumptions. The study found that fishing effort, not predator recovery, drives fishery yields in the North Sea.
Platelet-derived PITTs (Platelet-derived Integrin- and Tetraspanin-rich Tethers) are released from platelets during severe pathological conditions, driving damaging inflammatory processes. Blocking αIIbβ3 with monoclonal antibodies reduces PITT formation and tissue damage in disease models.
A new machine learning framework for satellite-based CO2 retrievals provides highly accurate concentration estimates while quantifying uncertainty, outperforming traditional physics-based methods in speed and accuracy.
A new study using satellite data confirms that California's shift to electric vehicles is making measurable differences in air quality and public health. For every 200 ZEVs added, nitrogen dioxide levels dropped 1.1%.
Physicists report the first experimental observation of quantum state transfer enabled by hidden symmetries in a network of laser-written optical waveguides. This discovery dramatically expands the design space for quantum circuits, opening the gates towards new classes of networks for secure quantum communication and cryptography.
A new study develops a video-based method to measure cardiopulmonary coupling, synchronizing heartbeat and breathing variations without contact. This approach produces consistent results with traditional devices, offering a promising solution for long-term monitoring and comfort.
A research team at Kumamoto University has developed a breakthrough drug-delivery platform using a small-intestine-permeable cyclic peptide, enabling efficient oral delivery of insulin. This approach achieves a pharmacological bioavailability of approximately 33–41% relative to subcutaneous injection.
Researchers have developed a GNSS-only method that consistently outperforms existing methods in dense urban areas, enabling safer and more reliable autonomous navigation. The approach uses a probabilistic framework to estimate position without relying on carrier-phase integer ambiguity resolution.
Citizen science is essential for improving how restoration success is evaluated and managed over time. By integrating public observations into formal monitoring systems, restored wetlands can be better understood and maintained.
A statistically significant spike in shark bites occurs every October in Hawaiian waters, primarily driven by tiger sharks. The research found a strong link between the October spike and the tiger shark's reproductive cycle, specifically parturition, which occurs during September-October.
The new platform, led by PPPL, aims to speed up simulations needed to advance fusion energy research. STELLAR-AI will integrate CPUs, GPUs, and QPUs to tackle the challenges of private fusion companies, enabling faster design and optimization of stellarator devices.
Researchers develop a novel DNA origami-based method to synthesize stable, monolithic amorphous silver nanostructures. The technique introduces geometric frustration that suppresses crystallization in metallic silver, resulting in high-stability and disordered atomic arrangements.
Researchers used molecular dynamics simulations to study how organic molecules move with supercritical water inside carbon nanotubes. Aromatic compounds significantly slowed down their own motion and surrounding water, while alkanes moved relatively freely. Temperature played a key role in overcoming transport limitations.
A recently identified tree species in Australia, Rhodamnia zombi, is facing extinction due to myrtle rust, a fungal disease that attacks and kills its young shoots. Researchers are working on finding clean cuttings and propagating them to grow resistant seedlings, which may hold the key to resurrecting the 'zombie' tree.
Researchers found that biochar produced at high temperatures can effectively immobilize cadmium in soil, while low-temperature biochar may increase metal uptake by crops. The study highlights the importance of considering biochar production temperature and microbial interactions for effective heavy metal remediation.
Researchers created a new frequency-aware approach to crafting adversarial images that better match human visual perception. The method, called Input-Frequency Adaptive Adversarial Perturbation (IFAP), significantly outperformed existing techniques in structural and textural similarity.
A comprehensive review of 233 studies identifies the connection between workplace conditions and loneliness, highlighting the importance of job quality, stress management, and social support. Chronic loneliness harms emotional and cognitive well-being, while interventions such as mindfulness and volunteering can provide relief.
A new study published in The Lancet Obstetrics, Gynaecology, & Women's Health found that postmenopausal women receiving hormone therapy lost 35% more weight while taking tirzepatide, a GLP-1-based obesity medication. This research could help develop personalized strategies for managing cardiometabolic risk in postmenopausal women.
A study found that brief exposure to benzo[a]pyrene disrupted normal development and skeletal health in fish, with effects persisting across multiple generations. The researchers identified specific metabolic signatures that could serve as early warning indicators of long-term toxicity.
A research team at UNH uses unmanned aerial vehicles (UAVs) to monitor corn fields, providing insights into crop yields and disease risks. The study demonstrates the ability of UAV imagery to differentiate between corn varieties with high accuracy.
Researchers found that using words with clear opposites can shape people's sense of certainty when evaluating messages. This means that certain wording types can make messages less effective among skeptics, while boosting confidence among believers.
Researchers identified genes controlling cell wall changes in ripening pistachio hulls, which can lead to cracks and tears. The study also found that the physics of forces and humidity influence degradation, with applications for other non-berry fruit crops.
BrainHealth Week 2026 will explore precision brain health, biosensor technology, and mental resilience, offering actionable strategies for improving daily performance and quality of life. The event brings together industry leaders, scientific community, students, and the community at large to discuss practical roadmap for longevity.
A recent study from University Hospitals Cleveland Medical Center found that diagnostic abnormalities were no more likely to occur among adults with unintentional weight loss than among comparison patients. In most cases, the weight loss was not linked to a serious underlying condition, with only a .7% overall rate of cancer.
Researchers at the University of Rochester have developed a new way to harness the properties of tungsten carbide as a catalyst for producing valuable chemicals and fuels. The method, which involves carefully manipulating tungsten carbide particles at the nanoscale level, has shown promising results in reducing costs and increasing eff...
Researchers analyzed 58 human studies to investigate the link between gut microbiome imbalances and cognitive decline. The findings suggest that individuals with mild cognitive impairment and Alzheimer's disease have distinct gut bacteria profiles compared to healthy individuals.
The University of Houston is launching an online certificate program in film and media production and leadership to prepare students for careers in the growing film industry. The program aims to strengthen workforce development and build a career-ready workforce that attracts independent filmmakers to Houston.
A recent study led by researchers at Drexel University's Autism Institute found that early intervention is key to helping most non-speaking autistic children develop spoken language. The study suggests that duration of the intervention rather than intensity may be more effective in achieving outcomes for these children.
Researchers used machine learning to evaluate 1,773 bus stops across Massachusetts, identifying 13 crash-relevant characteristics and proposing countermeasures. The study found that bus stop types in mixed-use arterial corridors and dense urban cores have the highest prevalence of crashes.
Researchers found structural and functional differences between mitral annular calcification and rheumatic mitral stenosis, which may lead to inaccurate diagnoses and treatment. The study suggests using disease-specific diagnostic criteria and management guidelines for patients with MAC-related stenosis.
The W8Buddy study, a major real-world evaluation of digitally delivered specialist weight management pathways, is recruiting 450 participants from 4 Specialist Weight Management Services across England and Wales. The study aims to assess the long-term health benefits and economic impact of digital tools for obesity care.
American Heart Association names Indiana University head coach Curt Cignetti national college football Coach of the Year, marking a dramatic turnaround in his second season. The award honors exceptional leadership and excellence, with proceeds benefiting heart health research and awareness.
A study found that witnessing terminal lucidity in children is a profoundly spiritual experience, influencing caregivers' belief systems and sparking personal growth. Caregivers reported disclosing what they witnessed to others, receiving mixed reactions from healthcare professionals and colleagues.
Research reveals that nanoplastics amplify the toxicity of tire-derived chemicals, causing severe eye malformations and impaired vision in zebrafish embryos. The study highlights a previously underappreciated risk of combined pollution, emphasizing the need for integrated approaches to environmental management.
The American College of Lifestyle Medicine (ACLM) has elected seven new members to its Board of Directors, bringing diverse expertise in clinical practice, public health, and education. The new board members will support ACLM's efforts to integrate lifestyle medicine into healthcare, furthering the field's growth and impact.
Researchers are studying microchimeric cells that can play complex roles in a person's body, including healing wounds and regulating the immune system. However, more research is needed to understand their role in health outcomes, particularly pregnancy complications and autoimmune diseases.
Researchers have resurrected ancient nitrogenases, enabling a new window into the origins of life on Earth. The study provides insights into the evolution of early life and its relevance to understanding life elsewhere in the universe.
Researchers at Tufts University used sourdough starters to test a pairwise interaction model that reliably forecasts how up to nine microbial species will interact. The study provides insights into predicting microbial coexistence, improving food safety, and informing human health.
Researchers at Rockefeller University discovered that fruit flies use a two-neuron system to calculate wind direction, leveraging double-duty signaling mechanisms. This finding redefines our understanding of how neurons compute direction and navigate their environment.
A study published in Stem Cell Reports suggests that transferring young microbiota to the intestines of older mice can speed up healing and improve the regenerative potential of intestinal stem cells. This approach may have implications for treating gut-related conditions such as inflammatory bowel disease.
A new study found that high body mass index (BMI) increases the risk of vascular-related dementia. The researchers believe treating or preventing high blood pressure may help reduce this risk. Early weight-loss interventions could potentially prevent dementia, especially vascular-related dementia.
Researchers at Mount Sinai detail how decades of cancer vaccine research have converged into more precise and effective immunotherapies. Decades-long clinical trials show personalized neoantigen vaccines are safe and capable of generating robust immune responses across various cancers.
Researchers previously estimated a powerful earthquake on Chalke Island in 1843 caused up to 600 deaths and a tsunami. However, a new study finds the event was likely a magnitude 5.93 earthquake with no deaths or tsunami reported at the time.
Sujuan Ba, CEO of the National Foundation for Cancer Research, has been recognized as one of OncoDaily's 100 Most Influential CEOs in Oncology in 2025. Under her leadership, NFCR has strengthened its role as a strategic accelerator of cancer research, supporting innovative science and fostering cross-sector collaboration.
The collaboration aims to deliver life-saving treatments at a fraction of their current market cost, using Caring Cross's decentralized manufacturing model. Clinical data demonstrated robust increases in fetal hemoglobin with sustained mitigation of SCD disease manifestations.
A new study from the University of Illinois examines how apple growers might respond to a potential ban on antibiotics, finding that proactive growers will benefit if the ban is enforced, but may struggle if it doesn't materialize. The study also shows that crop value can mitigate the negative impact of regulatory uncertainty.
Mannitol outperforms other green additives in slowing re-polymerisation of cellulose-lignin linkages, cutting molecular weight and raising hydrogenolysis monomer yield. The additive forms an average of 28 hydrogen bonds per simulation box, effectively capping sites where carbocations normally form.
Scientists have recovered a genome of Treponema pallidum from 5,500-year-old human remains in Colombia, pushing back the genetic record of this pathogenic species by over 3,000 years. The discovery sheds new light on the evolutionary history of treponemal pathogens and their occurrence in human populations.
The American Association for the Advancement of Science (AAAS) has partnered with Research Networks to publish Computational and Structural Biotechnology Journal, Computational and Structural Biotechnology Reports, and Brain Organoid & Systems Neuroscience Journal as Science Partner Journals. These journals will publish high-quality re...
Researchers at the University of Nottingham created intricate 3D printed surface textures that preferentially bounce incident particles in particular directions. This helps keep unwanted particles out of the way, allowing useful particles like atoms to be delivered more efficiently.
Researchers at UC Irvine's Nanoscale Communication Integrated Circuits Labs developed a unique transceiver that operates in the F-band spectrum, enabling speeds of up to 120 gigabits per second. This technology offers massive bandwidths and can transform how machines, robots, and data centers communicate.
A new treatment method combining metacognitive therapy and job focus has been shown to significantly reduce absenteeism due to mental illness. By getting people back to work faster, it can save society up to three times as much as it costs.
Astronomers may need to look beyond the traditional habitable zone for liquid water and potentially life-friendly conditions. A new study suggests that tidally locked worlds, even those orbiting closer to cool M- and K-dwarf stars than previously thought, could sustain liquid water on their night side.
Researchers at the Boyce Thompson Institute have developed new tools to study the molecular level of plant-fungus partnerships. By identifying key proteins involved in nutrient exchange, they aim to develop crop varieties that form more effective symbioses, reducing fertilizer costs and improving crop resilience.
Scientists at the University of Surrey have created ultra-sensitive nanofiber-based sensors that can harness power from gentle movements, enabling continuous and maintenance-free sensing. These breakthrough sensors have potential applications in sleep disorder monitoring and dementia care.
Research at the University of Colorado Anschutz Linda Crnic Institute found significant alterations in liver metabolism among individuals with Down syndrome, including elevated bile acids and biomarkers of liver dysfunction. The study suggests that dietary interventions may help improve health outcomes.
Researchers are expanding options for patients with hard-to-treat cancers using a personalized approach that identifies effective therapies by testing large libraries of drugs on living tumor cells. The approach has shown stronger responses than initial findings, suggesting it can reveal opportunities missed by traditional methods.
Researchers used CT scans and AI to find links between poorer abdominal muscle measures and higher incidence of falls in middle-aged adults. Maintaining good core strength throughout adulthood may provide benefits that start in midlife and continue into older adulthood.
Researchers used game theory and individual-based models to show how attack and defense strategies emerge as stable patterns, providing a theoretical framework for understanding predator–prey interactions. The study highlights the importance of sensory abilities for survival and challenges traditional views of predator-prey relationships.
New study finds that progenitor cells in the brain continuously produce new myelin-producing oligodendrocytes, despite being inefficient. This process suggests that treatments harnessing their developmental aspects may increase rapid myelin repair for demyelinating diseases like multiple sclerosis.
Researchers use ground-based seismic sensors to detect sonic booms from reentering space debris, estimating its trajectory, size, composition, and potential impact locations. The approach was tested on the Shenzhou-15 orbital module's reentry, revealing a progressive fragmentation pattern that matched eyewitness reports.
The Käte Hamburger International Centre will study messianic figures and discourses throughout history, aiming to understand their impact on democracies and promote critical awareness. The centre plans initiatives in schools and educational settings to educate students about recognising messianic phenomena.
A new study shows that China can significantly limit its cooling-related climate impacts by transitioning to cleaner refrigerants and adopting high-efficiency cooling technologies. This integrated approach could phase down cumulative HFC consumption by 12.6 Gt CO2e from 2022 to 2060, avoiding up to 0.015°C of global warming.
A study published in PLOS Biology found that males rate computer-generated figures with a larger penis as more intimidating and sexually competitive. Women also prefer taller, more V-shaped males with a larger penis, but beyond a certain point, further increases in size have diminishing benefits.
Researchers at Tohoku University's WPI-AIMR propose Harvested Reservoir Computing framework that harnesses road traffic dynamics for energy-efficient AI systems. The approach yields better prediction accuracy before congestion begins, reducing computational overhead and energy consumption.
A 5,500-year-old Treponema pallidum genome from Colombia sheds light on the emergence of syphilis, suggesting its origin was linked to social and ecological conditions of hunter-gatherer societies rather than agricultural intensification. The study's findings expand our understanding of treponemal diseases worldwide.
Research by Université Laval found that physical exercise and living in favorable conditions reduce depression risk by maintaining blood-brain barrier integrity. Fgf2 protein plays a key role in this mechanism and may serve as a biomarker for mood disorders.
Researchers at Heriot-Watt University have developed a method to remove unwanted tissues, such as tumors, with high precision using deep-ultraviolet lasers. The study demonstrates 10-micrometre precision with no detectable collateral damage.
Researchers have developed an efficient biosynthesis method for medicarpin in engineered yeast. The study involved the coordination of multiple metabolic pathways to produce high yields of medicarpin, overcoming supply chain and sustainability challenges associated with conventional methods.
A new preventive intervention called REconnect has been developed to reduce loneliness among university students. The program aims to strengthen social ties and inclusion before loneliness becomes chronic, with encouraging results showing increased life satisfaction and reduced loneliness.
The Assessing Genetic Diversity in Africa (AGENDA) project has generated whole-genome sequence data from over 1000 individuals from underrepresented communities, aiming to correct the imbalance in global genomic datasets. This effort will help predict disease risk and tailor treatments more effectively for African populations.
The JEDI Draghi Tracker measures Europe's implementation of the Draghi report on competitiveness, focusing on 20 impactful measures. Currently, only 14% has been implemented after 15 months.
The study found that women in agriculture suffer more from rising temperatures, while simple home modifications such as white-painted roofs and insect screens improved living conditions. The results are also relevant for adapting to climate change in Germany, with a focus on affordable and sustainable measures.
The University of Texas MD Anderson Cancer Center has made significant advancements in cancer care through its collaborative efforts between clinicians and scientists. These breakthroughs include an immune-targeting vaccine that shows promise in intercepting cancer in patients with Lynch Syndrome, a novel immunotherapy that demonstrate...
Malicious AI swarms can generate vast amounts of persuasive content, infiltrate online communities, and create adaptive campaigns that harm democratic discourse. The authors propose a distributed 'AI Influence Observatory' to guide independent oversight and action.
The Center for AI Responsibility and Research will build upon Binghamton research advancing AI for the public good. The new center is supported by a $30 million commitment from Tom Secunda and $25 million from Gov. Hochul and the NY State Legislature.
Researchers discovered that endogenous retroviruses play a crucial role in early human embryo development. These genetic remnants of ancient viral infections help drive the activation of genes required for successful development, with reduced expression leading to impaired zygotic genome activation and embryo arrest.
The report shows a notable increase in medication treatments, such as chemotherapy, immunotherapy, and hormone therapy, used before surgery to treat many cancers. Neoadjuvant systemic therapy increased notably for certain cancers, including gynecologic cancers, pancreatic cancer, and rarer abdominal lining cancers.
Researchers developed a new bioinformatic framework to reconstruct polyploid genome evolution, applying it to the cultivated octoploid strawberry. The approach identifies subgenome structure and infers the timing of major genome-merging events, clarifying debates about the evolutionary origin of modern strawberry.
Researchers have found that teosinte-derived traits in corn can alter the relationship between plants and soil microbes, improving nitrogen cycling and potentially making corn production cheaper. By reintroducing these traits, modern maize becomes more sustainable.
Researchers use seismic data to pinpoint the trajectory of falling debris, providing near-real-time tracking and rapid retrievals. This innovation complements radar data and can help locate potential crash sites, retrieve hazardous objects, and mitigate environmental risks.
A new study published in Otolaryngology–Head and Neck Surgery found that GLP-1R agonists are associated with reduced need for revision sinus surgery and biologic therapies in obese patients. The study analyzed data from over 100 million patient records and showed a 36% reduction in revision surgery rates at one-year follow-up.
Researchers have successfully controlled the rotation of molecules suspended in liquid helium nano-droplets using a new optical centrifuge. This breakthrough enables scientists to study the behavior of exotic, frictionless superfluids and understand how molecules interact with the quantum environment at various rotational frequencies.
A study published by the National Institutes for Quantum Science and Technology found that carbon-ion radiotherapy provided durable tumor control with minimal side effects while preserving breast appearance in carefully selected patients who were unable or unwilling to undergo surgery. The treatment resulted in excellent local control ...
A new global dataset quantifies biodiversity loss in international trade of staple crops, revealing a strong upward trend and key contributors. Soybean trade shows the most rapid increase, surpassing wheat, while major agricultural producers drive global biodiversity loss patterns.
The new process generates formate and hydrogen from glycerol through electrolysis, producing only CO2-neutral formates when powered by green electricity. The method uses an innovative copper-palladium catalyst, which could contribute to the electrification of the chemical industry.
Researchers at the University of Arizona have developed a copper-based compound that can kill MRSA bacteria by disguising itself as iron. The compound, BMDC, works by delivering a toxic dose of copper to bacterial colonies, making it an effective treatment against drug-resistant infections.
Researchers developed a new method to predict how cancer cells evolve by gaining or losing whole chromosomes, mapping favorable or harmful changes. ALFA-K quantifies how whole-genome doubling helps cancer cells survive high levels of chromosomal instability, laying the groundwork for evolution-aware approaches to cancer treatment.
Researchers found that activating specific healing pathways in fibroblasts from facial tissues can lead to regenerative wound healing with reduced scarring. This study could lead to new treatments for scar formation and its associated complications, including chronic pain and disease.
A new study from the Universities of Bath and Waterloo finds that people are more emotionally affected by anticipating negative future outcomes than positive ones, shaping economic behaviour. Individuals with stronger negative anticipatory emotions are more likely to avoid risk and less willing to wait for delayed outcomes.
Research from Goethe University Frankfurt reveals that many zoo mammal populations are becoming demographically fragile due to declining birth rates and increasing numbers of older individuals. This trend poses a threat to species conservation goals, as stable and resilient populations are crucial for addressing biodiversity loss.
Salk Institute scientists discover that dietary supplementation of the amino acid methionine protects infected mice against inflammation-related wasting, blood-brain barrier dysfunction, and death. Methionine boosts kidney filtration, reducing circulating cytokine levels and improving disease outcomes.
The event highlighted urgent global risks and science-led solutions for antimicrobial resistance, trust in data, and AI-enabled sustainable cities. Experts emphasized the need for immediate actions against AMR, which could kill more people than cancer by 2050.
Mangroves in tropical countries are being overwhelmed by land- and sea-based waste, posing a significant threat to environmental balance, biodiversity, and human well-being. The study highlights the urgent need for measures to reduce single-use plastic packaging to mitigate this problem.
A research team has demonstrated how quantum mechanical entanglement can be used to measure several physical parameters simultaneously with increased precision. By distributing atoms into up to three spatially separated clouds, the effects of entanglement act at a distance, reducing measurement uncertainties and canceling disturbances.
Physicists at University of Jyväskylä create long-sought two-dimensional topological material, exceeding 0.2 eV band gap and exhibiting topological edge states protected by crystal lattice symmetry. The strain-tunable material enables future advances in spin-based electronics and nanoscale devices.
Scientists at UNIGE created an AI tool called MangroveGS that can accurately predict the risk of cancer metastasis and recurrence. The algorithm uses gene expression signatures from colon cancer cells to identify key factors influencing metastatic potential, paving the way for more precise care and discovery of new therapeutic targets.
Researchers found that individuals with Alzheimer's disease have reduced brain complexity in response to magnetic stimulation compared to healthy controls. This suggests that brain stimulation may be used to evaluate the integrity of conscious processing in people with AD.
A new study reveals that around one-third of all newly written software functions in the United States are already being created with AI support, with productivity gains mainly driven by experienced developers. The study found wide regional gaps, with the US leading at 29% AI-assisted code, while China and Russia lag behind.
Researchers have created validated tools to measure 'woke' attitudes on the political left and right. The study, published in Scandinavian Journal of Psychology, used a survey with over 600 respondents from Finland to test the scales.
Researchers found that particulate matter concentrations in Sarajevo exceed WHO recommended daily limits, with wood-burning stoves contributing to organic pollution. Sulphur dioxide emissions from old power plants also impact air quality, with the city's valley experiencing rapid pollutant drop at night.
Researchers explore polyherbal formulations combining multiple plant extracts to combat skin aging, featuring seven key plants with their bioactive phytoconstituents. These formulations offer a synergistic advantage, enhancing efficacy while reducing toxicity risks associated with single compounds.
Cancer mortality rates have decreased for breast cancer and leukemia, despite increasing incidence, while colorectal cancer has become the leading cause of death among US young adults. Colorectal cancer surpasses lung, breast, and prostate cancers as the leading cancer-related death in people under 50 years old.
A new study reveals that gut microbiota directly affects intestinal stem cell function, leading to impaired regeneration after injury. Restoring a more youthful microbiota can reverse the age-related decline in ISC activity.
Skin pigmented spots feature immune cell infiltration, branched blood capillaries, and a disrupted skin barrier, necessitating innovative skincare strategies. The study highlights the need for multi-action ingredients that soothe inflammation, normalize blood vessels, and maintain a healthy skin microbiome.
Commercially insured patients frequently bypass rural hospitals between 2012 and 2021, generating large payments for receiving hospitals. The findings highlight the need for addressing this issue to alleviate financial distress on rural healthcare facilities.
Researchers propose a new conceptual framework for neutrophils, highlighting their dynamic and adaptable nature. The study reveals neutrophils' functional diversification and immunological memory capabilities, opening avenues for innovative therapeutic strategies.
A study reveals that expanding existing mines worsens environmental and social risks over time, with many operations concentrated in high-risk contexts. The practice tends to draw less regulation due to its routine nature, unlike new mining projects.
A new study finds that soil salinization influences inorganic carbon storage, particularly in regions with elevated salinity. The research reveals a conditional relationship between salinity and inorganic carbon, highlighting the need to incorporate soil chemical processes into global carbon assessments.
The ISSCR has released a comprehensive roadmap for developing pluripotent stem cell-derived therapies, outlining critical scientific, manufacturing, and regulatory guidance. The Best Practices document provides a risk-based, end-to-end development strategy to support informed decision-making across seven essential areas.
Research published in Scientific Reports found that ancient giant kangaroos could withstand the strain of hopping due to robust hindlimbs. The study's findings suggest that these animals were unlikely to rely solely on hopping for locomotion over longer distances, but may have used short bursts of hopping to evade predators.
A retrospective study of 161 cases found that dermatofibrosarcoma protuberans (DFSP) of the head and face favors the cheek region, particularly in older patients. The dominant site accounted for 65.38% of all head-and-face DFSPs, suggesting regional anatomic or biological factors influence tumor development.
A new USC white paper reveals that PBMs' reported profit margins are influenced by accounting practices, making it challenging for policymakers to understand the true cost drivers. The researchers suggest requiring financial transparency from PBMs to develop a better picture of their operations and costs.
Scientists studying giant fossilized kangaroos discovered that they could still hop, contradicting previous beliefs. The analysis of foot bones and ankle tendons revealed that these prehistoric kangaroos had adapted differently to manage their enormous size, enabling them to bounce.
Researchers have characterized the association between cellular senescence and human brain structure in both development and late life. The study found that senescence-related gene expression is linked to brain volume and cortical organization, with distinct roles depending on cell type and stage of life.
Researchers have found that chemicals in exhaled breath can reveal the composition of the bacteria living in the intestines, providing a potential non-invasive test for monitoring and diagnosing gut health issues. Breath samples from children with asthma were able to predict the presence of the bacterium linked to the condition.
Researchers found that TL1A, a key immune signaling protein, stimulates the growth of new white blood cells in the bone marrow, which then promote tumor formation in the gut. The study suggests that blocking TL1A activity could be an effective strategy to treat IBD and prevent associated colorectal tumors.
A new study finds that hospitals treating more patients with Medicare Advantage plans face higher readmission penalties despite taking similar actions to prevent repeat hospitalizations. The analysis highlights the need to incorporate Medicare Advantage data into the Hospital Readmissions Reduction Program.
Dr. Manuel A. Friese has been recognized for his groundbreaking work studying the interactions between inflammation and nerve cell death, which drives disease progression in multiple sclerosis (MS). His research aims to identify new therapeutic targets and bring the field closer to stopping disease progression.
The study demonstrated that black ginseng extract reduces MMP-1 expression and suppresses PGE2 levels in human foreskin fibroblasts, promoting skin homeostasis. It also identified rare ginsenosides as key molecules involved in the anti-inflammatory effects of BGE.
Cancer researchers have identified a key mechanism by which cancer cells protect themselves from the immune system. The study found that MYC protein can bind to RNA molecules, eliminating alarm signals that would activate the immune defense.
Researchers developed a novel, computer-based method called CoBiSe to design and produce genetically encoded fluorescence-based biosensors for rapid and simple production. The new iron sensor 'IronSenseR' detects iron (II) with high sensitivity without binding to iron (III) or other metal ions.
Scientists have developed a novel immunotherapy approach that targets tumor macrophages, converting them from immune suppressors to killers. The therapy, using engineered CAR T cells, has shown promising results in preclinical models of metastatic ovarian and lung cancer.
A new study reveals that strong Central Pacific El Niños self-destruct due to negative feedbacks from distant oceans, while weaker events survive by forming a lasting partnership with the North Pacific climate pattern. This discovery enables forecasting months in advance with over 80% accuracy.
Science MMAI Gym trains LLMs in medicinal chemistry, biology, and clinical development with precision required in pharma R&D. Partner models emerge with up to 10x improvements in performance, matching state-of-the-art specialist models.
Myosteatosis is a key predictor of poor clinical outcomes across a spectrum of liver diseases, with associations to severe disease phenotypes, hepatocellular carcinoma, and increased mortality. Nutritional intervention, exercise prescription, and potential management strategies are proposed to address this condition.
The American Heart Association is hosting multiple pre-conference symposia at the International Stroke Conference in New Orleans, February 4-6, 2026. These symposia cover topics such as state-of-the-science stroke nursing, brain health, and addressing disparities in stroke care. The events are designed to advance stroke and brain healt...
Researchers developed a new imaging technology called fast-RSOM that captures detailed images of the smallest blood vessels directly through the skin. This technology can detect early signs of cardiovascular risk, enabling doctors to intervene sooner and guide personalized therapies.
Insilico Medicine presents three abstracts at the 2026 Crohn's & Colitis Congress highlighting clinical, preclinical safety, and efficacy data for ISM5411. The first-in-human Phase 1 results show no serious adverse events or deaths reported, with a favorable pharmacokinetic profile supporting gut restriction.
Researchers at UW-Madison have resurrected a 3.2-billion-year-old nitrogenase enzyme to improve our understanding of the origins of life on Earth and potentially recognize signs of life elsewhere.
A new study published in The Journal of Clinical Endocrinology & Metabolism found a causal link between high body mass index (BMI) and dementia. High blood pressure was identified as a driving factor behind the increased risk. Researchers suggest that preventing or treating obesity and high blood pressure could help reduce dementia risk.
Bacterial infections are common and severe complications in patients with liver cirrhosis, with a global prevalence of 35.1% reported. The most common infection sites were the gastrointestinal tract, ascites fluid, and urinary tract, with gram-negative organisms more frequent than gram-positive organisms.
A new study by Penn State researchers found that the level of transparency in artificial intelligence (AI) systems affects users' trust. When systems meet or exceed users' expectations, trust increases without needing detailed explanations. However, when expectations are not met, users require more information and a deeper understandin...
Fecal microbiota transplantation (FMT) holds promise in treating chronic liver diseases by restoring gut-liver axis balance. The consensus recommends FMT for various etiologies, excluding drug-induced liver injury, with strict donor selection and management guidelines to ensure safety.
A nationwide study found that Parkinson's disease is more common among individuals with higher socioeconomic status and in the northern provinces of the Netherlands. The risk increases with age, peaking between 75 and 85 years, and is higher among men.
A team of researchers at EPFL developed a robotic hand that can detach from its arm and 'crawl' to grasp multiple objects, overcoming human asymmetry and limitations. The device can perform 'loco manipulation' with seamless autonomy and has potential applications in industrial, service, and exploratory robotics.
A study reviews decades of research on Hsp70's role in neurodegenerative diseases, highlighting its protective effects and potential therapeutic value. The review reveals that different Hsp70 isoforms interact with co-chaperones and cellular pathways to determine protein clearance.
Smoking exposure induces tumor microenvironment promoting sorafenib resistance in HCC by modifying the 14-3-3η proteome. Arsenic trioxide suppresses tumor progression with synergistic effect when combined with sorafenib.
A new theory of proprioception challenges traditional understanding by incorporating frontier bionic evidence. The proposed framework reconceptualizes proprioception as a dynamic augmentable interface, enabling functional movement and potentially improving rehabilitation outcomes in sports injuries and neurological diseases. Researcher...
A team of researchers from Chonnam National University explores how boosting consumer trust can increase adoption of second-life EV battery tech. They found that transparent safety inspections and tailored messaging can improve adoption outcomes.
Researchers develop Dual Perigee, a lightweight algorithm that streamlines network connections to enable secure and low-latency data sharing in IoT networks. The study reduces block-related delays by 48.54% compared to standard approaches.
A study by Chungnam National University finds that climate adaptation can significantly reduce migration from drought and armed conflict in Africa. Countries with stronger adaptive capacity experience lower migration levels during crisis conditions, highlighting the importance of policies addressing environmental and security threats.
A recent study found that organic matter carried from rivers into the Arctic Ocean creates more clouds and keeps the region cooler. Aerosol particles formed by this biological matter act as 'seeds' for cloud formation, increasing their ability to form bright, long-lasting clouds.
A new Perspective article explores the role of biofilms in health during long-duration spaceflight and how this research can reshape our understanding of microbial communities on Earth. The study highlights the importance of biofilms in enabling human and plant health, particularly in space-based environments.
Researchers found that combining selective CDK2 inhibitor BLU-222 with CDK4/6 inhibitors produces strong, durable anti-tumor effects across preclinical models of breast cancer. This approach targets cancer cells' reliance on CDK proteins and restores control over the cell cycle in resistant tumors.
Research reveals that chemotherapy alters the gut microbiota, producing indole-3-propionic acid, which travels to the bone marrow and rewires immune cell production. This leads to a metastasis-refractory state in preclinical models and improved survival outcomes in patients with colorectal cancer.
Smartwatches with PPG and ECG functionality improve atrial fibrillation detection, detecting it four times more often than standard care. Researchers detected heart arrhythmia in 21 patients using smartwatches compared to five in those receiving standard care after six months of monitoring.
A new study has found that living walls can significantly enhance urban biodiversity by attracting pollinators and other wildlife. The research revealed that soil-based living walls with plants in soil attracted more wildlife than those with artificial substrates, and specific plant species like ivy and honeysuckle were most effective.
Researchers have developed a new AI method called Riff-Diff to construct artificial biocatalysts, resulting in enzymes that are significantly faster, more stable and versatile. The technology allows for precise design of protein structures around active centres, making enzyme design more accessible to the wider biotechnology community.
A team of researchers from Institute of Science Tokyo developed a novel enzyme, MAN, that efficiently converts common nucleotide substrates into RNA nucleotides with remarkable efficiency. This method simplifies the production of RNA building blocks by using inexpensive and stable polyphosphate as a phosphate donor.
Researchers at Kobe University have identified a specific bacterial strain, Staphylococcus epidermidis and Corynebacterium tuberculostearicum, as the primary causes of foot odor in Nagashima-type palmoplantar keratosis. Topical application of benzoyl peroxide reduces odor by decreasing C. tuberculostearicum levels.
Researchers found that humans in northern Mozambique use distinct calls, trills, grunts, whoops, and whistles when communicating with honeyguide birds. These regional dialects allow communities to coordinate cooperation with greater honeyguides, revealing a striking parallel to human language diversification.
Researchers have developed a new way to produce fluorescence by using molecular stacking, which can lead to the creation of smarter and more sensitive pressure sensors. The study focused on two crystalline organoboron compounds that exhibit piezofluorochromism, changing color in response to pressure.