The INSULIN Act would cap out-of-pocket insulin costs at $35 per month for people on private insurance, establishing a resource center and hotline for uninsured individuals. The Endocrine Society applauds the bipartisan bill, which aligns with its Insulin Access and Affordability Position Statement.
A review of existing evidence on testosterone and heart health found that both low and high testosterone levels increase the risk of atrial fibrillation. The risk appears to follow a U-shaped pattern, with the lowest risk in the middle of the normal testosterone range. This suggests that treatment should be individualized and monitored.
A recent study published in the Journal of the Endocrine Society suggests a link between exposure to phthalates and elevated blood pressure during pregnancy. Pregnant women with higher levels of fragrance-associated phthalates were found to have higher systolic and diastolic blood pressure markers, increasing their risk of hypertensive...
The Endocrine Society recommends a diagnosis of hypogonadism based on low testosterone levels and symptoms. Testosterone replacement therapy (TRT) can improve quality of life for men with appropriately diagnosed hypogonadism, but its long-term safety is uncertain. Standardized testing and monitoring are crucial to minimize risks.
A recent study found that women and individuals with minimal motivation to lose weight experienced greater weight loss on tirzepatide. The research also identified baseline clinical, demographic, and behavioral variables associated with weight loss trajectories over 12 months.
Clinical trials suggest that GLP-1s can improve testosterone levels and sperm quality in men with obesity-related low testosterone. The research also found that GLP-1s address the underlying effects of obesity on fertility. The studies showed no negative impact on hormones, sexual function, or sperm quality.
A new study reveals that obesity is reshaping the global cardiovascular disease crisis, with heart disease now peaking in people aged 50-54 rather than the elderly. The study projects over 1.37 million premature cardiovascular deaths attributed to obesity by 2050, primarily in South Asia and low-income countries.
A recent study found that long naps may increase the risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD) in people with type 2 diabetes. MASLD is characterized by excessive fat buildup in the liver, which can lead to chronic disorders like NAFLD.
A study of 165,832 women found that later menarche is associated with an increased risk of tobacco use disorder and various conditions, including digestive issues, heart problems, and brain disorders. The researchers suggest a shift in perspective to recognize childhood influences as the primary cause of adult health problems.
A study found that tirzepatide significantly increases brown adipose tissue activity and volume in premenopausal women with obesity. The medication also shows potential signs of converting white subcutaneous fat into more metabolically active 'beige' fat.
A retrospective cohort study found that menopausal hormone therapy significantly reduces the risk of low bone mineral density by 69% compared to non-users. This suggests that hormone therapy could be an effective way to prevent bone loss and lower fracture risks in women after menopause.
A study presented at ENDO 2026 found semaglutide was associated with a 15% reduction in bone fractures and greater weight loss compared to other anti-obesity medications. The results suggest that semaglutide may have beneficial effects on bone health in people with type 2 diabetes.
A study found that nearly 4 in 10 patients stopped GLP-1 medication within the first year and nearly two-thirds restarted therapy within two years. The researchers also identified sociodemographic, clinical, and provider-level predictors of discontinuation, including Medicaid or Medicare status, Black patients, and side effects.
The first real-world study of fezolinetant found the treatment improved hot flashes, depression, and anxiety in women with menopausal vasomotor symptoms. In a study of 656 women, fezolinetant significantly reduced hot flash symptoms and showed benefits similar to those seen in clinical trials.
A study presented at the Endocrine Society's annual meeting found that exposure to the plasticizer DEHP in early development can lead to increased anxiety-like behavior in adult male rats. The research suggests that humans exposed to endocrine disruptors before and shortly after birth may experience long-lasting behavioral changes.
A study of 336 mother-infant pairs found that breast milk and infant urine contained over 50 different chemicals, including BPA and phthalates, which can interfere with hormones during baby's development. These chemicals were detected in breast milk and urine up to 6 months after birth.
A nationwide study of over 5.7 million women aged 40 found a link between longer reproductive spans and an increased risk of thyroid cancer. The research also showed that hormone replacement therapy, especially for five years or more, was associated with a higher risk of developing the disease.
The study found a significant increase in type 1 diabetes cases among Hispanic/Latino adolescents in Puerto Rico, from 10.1 per 100,000 in 2009 to 24.1 in 2021, with an average annual increase of 4.1%. This trend has important implications for patient care and public health.
A study published by the Endocrine Society found that testosterone therapy was often prescribed without adequate diagnostic testing, highlighting opportunities for quality-improvement efforts. The research suggests that targeted interventions may be needed to improve guideline-concordant prescribing practices and prevent avoidable risks.
A study found that testosterone alone is not enough to prevent type 2 diabetes in older men; lifestyle interventions are crucial for improving blood sugar control and reducing obesity. Testosterone treatment can improve body composition and sexual desire, but its benefits diminish over time.
Researchers found that eliminating sugar from a low-fat diet can lead to impaired glucose control, insulin resistance, and gut microbial imbalance. Balanced dietary carbohydrates are essential for supporting gut and immune homeostasis.
A new AI model analyzed 30 years of EHR data to identify patients with primary aldosteronism, a common cause of high blood pressure. The model correctly flagged over 90% of cases while missing fewer than 10%, suggesting it could improve screening for this condition.
A comprehensive analysis of solid-organ transplant recipients found that both existing and new-onset diabetes significantly increase mortality risk. Organ transplant recipients who developed or have diabetes after surgery had a higher risk of death compared to those without diabetes, with kidney recipients having the highest risk.
A study found that adults taking GLP-1 receptor agonist medications experienced significant decreases in daily step counts and moderate-to-vigorous physical activity, highlighting the need for targeted interventions to promote exercise alongside obesity treatment.
Children who start puberty earlier than usual may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline. The guideline suggests different approaches for various subgroups, including monitoring girls with slow progression and using simpler testing methods.
The Endocrine Society and Keystone Symposia will host their first joint conference in October to explore discovery in cancer, diabetes, and cardiometabolic disease. The conference series aims to strengthen the exchange of scientific knowledge through coordinated programming, facilitating discovery and collaboration among researchers.
Italian researchers Anna Pilatone and Gabriella Milan won the Endocrine Society's 2026 Endocrine Images Art Competition with their image of a pre-adipocyte cell, highlighting the complexity of adipose tissue in obesity. The winning entry will be displayed at ENDO 2026 and featured in Endocrine News magazine.
A ketogenic diet has been shown to improve beta-cell function in patients with type 2 diabetes by decreasing proinsulin secretion and reducing pancreas stress. This improvement is associated with changes in the proinsulin-C-peptide ratio, a biomarker of pancreas stress.
The Endocrine Society suggests that redefining obesity beyond BMI could complicate diagnosis and delay treatment. The proposed framework requires clinicians to prove organ dysfunction is caused by body fat for a clinical obesity diagnosis. This approach may hinder access to effective obesity treatment.
The Endocrine Society supports the INSULIN Act to address insulin affordability, setting a $35 monthly cap for people with private insurance and creating a program for uninsured individuals. The bill aims to reduce insulin prices by encouraging competition in the market.
Early-life exposure to PFAS may influence how teens' bones develop during adolescence, leading to lower bone density. The study found that teens with higher PFAS levels had lower forearm bone density, with stronger associations among females.
A mouse study found that a father's nicotine exposure can affect his offspring's ability to process sugar, potentially contributing to diabetes risk. The study's findings suggest that tobacco use in men may be linked to an increased risk of their descendants developing diabetes.
The Endocrine Society has elected Joy Wu as its 2027-2028 President, a board-certified endocrinologist with a focus on osteoporosis and bone health. Wu is also a leading researcher in stem cell therapies for bone formation and prevention of cancer metastases to bone.
The Endocrine Society's annual meeting ENDO 2026 offers journalists the opportunity to discuss groundbreaking research on various hormone-related topics with world-renowned experts. Over 7,200 attendees, 100 exhibitors, and nearly 2,500 abstracts are expected.
The Endocrine Society has announced its inaugural Rare Endocrine Disease (RED) Fellows Program, designed to improve outcomes for people living with rare endocrine diseases. The program addresses critical gaps in awareness, diagnosis, and care through a partnership with the National Organization for Rare Disorders.
A new study published in The Journal of Clinical Endocrinology & Metabolism found a causal link between high body mass index (BMI) and dementia. High blood pressure was identified as a driving factor behind the increased risk. Researchers suggest that preventing or treating obesity and high blood pressure could help reduce dementia risk.
A new study found that maternal thyroid hormones are crucial for fetal neurodevelopment, and gestational thyroid imbalance increases the risk of autism spectrum disorder. Women with persistent thyroid dysfunction across pregnancy were at a higher risk of having children with autism.
People with higher muscle mass, as indicated by stronger grip strength, are less likely to develop organ damage or die from obesity. Building and maintaining muscle through weight training may be a practical way to identify individuals at risk and act early.
Researchers have found that GLP-1 therapies may help reduce alcohol and other substance use by modulating neurobiological pathways underlying addictive behaviors. The therapies, which are commonly used to treat diabetes and obesity, have shown encouraging results in early clinical trials.
The Endocrine Society has recognized 12 exceptional endocrinologists with its 2026 Laureate Awards, honoring their groundbreaking research and clinical breakthroughs in treating hormone disorders. The winners include Robert M. Carey, Christopher Kevin Glass, Rebecca Reynolds, Samuel Klein, and Lisa B. Nachtigall, among others.
A recent study published in the Journal of the Endocrine Society found that skipping breakfast and having late dinners are associated with an increased risk of osteoporosis. Additionally, unhealthy eating habits were linked to other lifestyle risk factors such as physical inactivity, smoking, and insufficient sleep.
The Endocrine Society guideline suggests universal screening for primary aldosteronism in people with hypertension. This condition is associated with a higher risk of cardiovascular disease if left undiagnosed and untreated.
A new mouse study suggests that watching others eat, especially palatable food, can cause overeating in the absence of hunger. The study found that satiated mice increased their intake of sucrose diet when observing fasted peers, but dopamine receptor inhibitors suppressed this behavior.
Despite supply shortages and insurance coverage obstacles, patients taking GLP-1 medications achieve clinically significant weight loss when paired with intensive lifestyle interventions. The study found that consistent medication courses combined with lifestyle changes and support remain the most effective weight-loss program option.
Adrenal hormone function was restored in animal studies using implantable cell therapy, demonstrating potential for a functional cure for primary adrenal insufficiency. The treatment also followed the animals' natural circadian rhythm and showed improved survival rates.
A new study found that anti-obesity medications can normalize testosterone levels in men with obesity or type 2 diabetes. This positive effect on reproductive health was observed after a 10% weight loss, with total and free testosterone levels increasing by 24%.
A study published by The Endocrine Society found that obesity and early type 2 diabetes in adolescence can interfere with bone development, potentially increasing the risk of fractures and osteoporosis later in life. Researchers followed 48 teenagers for a year, finding that teens with obesity and type 2 diabetes showed less improvemen...
A novel AI-powered retina tracker, SMART, analyzes retinal images with near-perfect accuracy in under one second, offering hope for sight-saving screenings for diabetic retinopathy. The tracker expands access to high-quality retinal assessments globally, reducing vision loss from diabetic retinopathy.
A study found that night shift work disrupts the body's internal timing, causing irregular reproductive cycles and hormonal imbalances. Women exposed to shiftwork-like light exposure had a higher risk of ovarian disruption, pregnancy complications, and difficult labor, even if they were not experiencing disrupted cycles.
A new study by The Endocrine Society finds a strong link between acromegaly and an increased risk of various cancers, often at younger ages than expected. Patients with the rare growth hormone disorder had higher rates of certain types of cancer, including colon, gastric, breast, lung, ovarian, prostate, and blood cancers.