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University Hospitals Cleveland Medical Center


Acupuncture significantly reduces stress, pain, and anxiety for patients undergoing IVF

A recent study found that acupuncture and traditional Chinese medicine significantly improves patient-reported levels of stress, pain, and anxiety during IVF treatment. Clinically meaningful improvements were seen with average reductions of 2.2 units in anxiety, 2.1 in stress, and 1.4 in pain.

SourceUniversity Hospitals Cleveland Medical Center·JournalGlobal Advances in Integrative Medicine and Health·DateJun 18, 2025

University Hospitals Harrington Heart & Vascular Institute unveils new structural heart program, cardiac catheterization lab at UH Lake West Medical Center

The new program offers minimally invasive treatments for cardiovascular issues, including transcatheter aortic valve replacement and left atrial appendage occlusion. The cardiac catheterization lab features state-of-the-art equipment, allowing improved diagnostic imaging and safer procedures.

Cuyahoga County Healthcare Sector Partnership, Cleveland Clinic and University Hospitals launch initiative to train more nurse educators

The Cuyahoga County Healthcare Sector Partnership is launching an initiative to train more nurse educators, aiming to address the national nursing educator shortage in Northeast Ohio. The program will recruit and train clinical faculty to support increased enrollment in nursing programs and reduce student waitlists.

Research team from Wesley Center for Immunotherapy at UH Seidman Cancer Center Awarded Top Scoring Abstract Award at the 2025 International Society for Cell and Gene Therapy Annual Meeting

A research team from UH Seidman Cancer Center developed an ultra-fast and highly scalable CAR T-cell therapy manufacturing platform, enabling wider utilization of the therapy. The approach resulted in significantly more favorable toxicity profiles compared to traditional CAR-T products.

Cholesterol drug repurposed as investigational therapy for HPV+ cancers at University Hospitals Seidman Cancer Center in nation’s first-ever clinical trials

Researchers at University Hospitals Seidman Cancer Center have successfully repurposed fenofibrate, a cholesterol drug, to treat HPV+ cancers. The study found that fenofibrate restores the function of key tumor suppressor gene p53 and reactivates immune cells, offering a potential targeted therapy for these cancers.

Chiropractic associated with reduction in opioid-related adverse drug events: new study

A new study found that adults with newly diagnosed sciatica who received chiropractic spinal manipulation experienced significantly lower rates of opioid-related adverse drug events compared to those receiving usual medical care. The study highlights the potential benefits of non-pharmacological approaches in managing pain.

University Hospitals and Case Western Reserve University collaborative science pilot awards infuse $250,000 to accelerate five promising research projects

The Collaborative Science Pilot Awards program aims to inspire innovative research projects across UH and Case Western Reserve. Five teams will focus on organizing an MR Fingerprinting database, developing a genetic risk aid for early keratoconus detection, analyzing Alzheimer's treatment mechanisms, treating gastrointestinal symptoms ...

Reiki therapy demonstrates significant symptom relief for cancer patients receiving infusion treatments

A study published in Journal of Pain and Symptom Management found that Reiki therapy resulted in clinically significant improvements in pain, fatigue, anxiety, nausea, and well-being among outpatients with cancer. The study involved 392 Reiki sessions for 268 unique patients, showing a mean improvement of 1.78 in pain and 2.09 in anxiety.

SourceUniversity Hospitals Cleveland Medical Center·JournalJournal of Pain and Symptom Management·DateDec 12, 2024

University Hospitals Connor Whole Health study finds spinal manipulative therapy benefits patients with tension-type headaches

A retrospective study of over 6,200 patients found that spinal manipulative therapy significantly reduced the need for butalbital prescriptions and medication overuse headache. Patients receiving SMT were also less likely to develop MOH, with only 1.7% prescribed butalbital compared to 3.8% in non-SMT groups.

SourceUniversity Hospitals Cleveland Medical Center·JournalHealth Science Reports·DateDec 3, 2024

University Hospitals Connor Whole Health uses patient feedback to improve intake experience

The study evaluated the functionality and acceptability of electronic intake forms in an outpatient Whole Health Center. Patients perceived the forms as relevant to their health concerns and valuable for communicating important information to providers. The forms were deemed easy to navigate, with minor suggestions for improvement.

SourceUniversity Hospitals Cleveland Medical Center·JournalGlobal Advances in Integrative Medicine and Health·DateNov 13, 2024

Large integrative medicine center implements processes to measure and understand clinical effectiveness

A new study published in PLOS ONE explores the implementation of a paper-based system for collecting patient-reported outcomes (PROs) in an outpatient integrative health and medicine (IHM) setting. The research found that provider, operational, and clinical-level factors have a greater impact on successful completion than patient factors.

Patients report significant symptom reduction within a single integrative medicine encounter

A new study by University Hospitals Cleveland Medical Center found that patients seeking outpatient integrative health and medicine (IHM) care experience clinically meaningful reductions in symptoms of pain, anxiety, and stress after just one treatment. For all IHM modalities, patients with moderate-to-severe symptoms reported clinical...

SourceUniversity Hospitals Cleveland Medical Center·JournalGlobal Advances in Integrative Medicine and Health·DateMay 15, 2024

New study finds chiropractic spinal manipulation does not increase the risk of cauda equina syndrome

A large retrospective cohort study found no increased risk of cauda equina syndrome in adults with low back pain who received chiropractic spinal manipulation. The study analyzed over 130,000 patients and suggested that underlying disc degeneration may be a risk factor for CES regardless of treatment approach.

Novel oral hormone therapy shows promising results for prostate cancer treatment with radiation therapy

A high-impact study demonstrates the safety and efficacy of relugolix in conjunction with radiation therapy for localized and advanced prostate cancer, achieving rapid castration and maintaining low testosterone levels. The study also shows no difference between relugolix and leuprolide in time to castration-resistant prostate cancer.

Researchers provide recommendations for understanding music therapy’s impact on chronic pain

A recent article recommends measuring meaningful outcomes such as pain interference, self-efficacy, and physical functioning to improve the evidence-base for music therapy within sickle cell disease populations. Music therapists can play an important role in chronic pain management by addressing stress, depressed mood, and loneliness.

SourceUniversity Hospitals Cleveland Medical Center·JournalNordic Journal of Music Therapy·DateMar 12, 2024

Study reveals disparities in use of evidence-based integrative pain management modalities among adults with chronic pain

A recent study found disparities in access to integrative health and medicine, as well as nonpharmacologic therapies, among vulnerable populations with chronic pain. These findings highlight the need for policy changes to promote equitable access to these evidence-based modalities.

SourceUniversity Hospitals Cleveland Medical Center·JournalJournal of Pain Research·DateJan 23, 2024

New study reveals significant reduction in lumbar spine reoperation with chiropractic spinal manipulation

A new study published in BMC Musculoskeletal Disorders found that chiropractic spinal manipulation significantly reduces the likelihood of undergoing additional lumbar surgery. Adults who received CSM for sciatica experienced a substantial 45% reduction in lumbar spine reoperation compared to those receiving usual medical care.

SourceUniversity Hospitals Cleveland Medical Center·JournalBMC Musculoskeletal Disorders·DateJan 16, 2024

Music therapy team increases collection of patient-reported outcomes to improve clinical research and practice

Researchers at University Hospitals Cleveland Medical Center implemented a quality improvement initiative to improve documentation consistency and increase the capture of patient-reported outcomes. The findings show that music therapists' rates of capturing PROs increased significantly, with notable improvements in stress, pain, anxiet...

SourceUniversity Hospitals Cleveland Medical Center·JournalJMIR Human Factors·TypeObservational study·DateJul 31, 2023

Study in journal Nature Communications finds high blood glucose levels sensitizes pancreatic cancer cells to chemotherapy

Researchers discovered that high blood glucose levels make pancreatic cancer cells more sensitive to chemotherapy, which could lead to improved treatment outcomes. In a mouse model and clinical data, the study found a nearly 40% lower risk of death among patients with elevated glucose levels compared to those with normal levels.

SourceUniversity Hospitals Cleveland Medical Center·JournalNature Communications·DateJul 26, 2023

Reduced likelihood of gabapentin prescription in U.S. adults receiving chiropractic spinal manipulation for low back pain

A study found that US adults with radicular low back pain receiving chiropractic spinal manipulation for low back pain had significantly lower odds of being prescribed gabapentin. The odds ratio was 0.53, indicating a meaningful reduction in gabapentin use among patients who received chiropractic care.

SourceUniversity Hospitals Cleveland Medical Center·JournalBMJ Open·TypeObservational study·DateJul 25, 2023

New study demonstrates how music therapy can be integrated across a large health system

A new study from University Hospitals Cleveland Medical Center describes the scope and integration of their music therapy program within10 UH medical centers. The study examined 14,261 music therapy sessions provided to 7,378 unique patients who had been referred by 1,169 healthcare professionals.

SourceUniversity Hospitals Cleveland Medical Center·JournalJournal of Integrative and Complementary Medicine·TypeObservational study·DateJul 14, 2023

A new study published in NEJM Evidence with University Hospitals Seidman Cancer Center researchers and ArteraAI validates the first-ever predictive AI biomarker of androgen deprivation therapy (ADT) benefit in prostate cancer

A new study published in NEJM Evidence validates a predictive AI biomarker for androgen deprivation therapy (ADT) benefit in prostate cancer. The study found that personalized use of short-term ADT could improve patient outcomes in men with predominantly intermediate-risk prostate cancer.

SourceUniversity Hospitals Cleveland Medical Center·JournalNEJM Evidence·TypeData/statistical analysis·DateJun 30, 2023

University hospitals and Case Western Reserve University research teams receive Collaborative Science Pilot Awards

Three University Hospitals and Case Western Reserve University research teams received $50,000 Collaborative Science Pilot Awards to explore innovative research projects. The awards aim to increase competitiveness and capacity for major external funding opportunities in key areas such as cancer, brain health and genetics.

New study shows non-optimal temperature is a significant contributor to cardiovascular disease burden globally

A new study published in European Journal of Preventive Cardiology reveals that non-optimal temperatures have a significant impact on global cardiovascular disease burden, contributing to nearly 1.2 million CVD deaths and 22 million disability-adjusted life years (DALYs) annually.

SourceUniversity Hospitals Cleveland Medical Center·JournalEuropean Journal of Preventive Cardiology·DateMay 2, 2023

New study finds unintentional weight loss often goes unrecognized by primary care physicians

A new study found that unintentional weight loss is grossly under-recognized in primary care, with only 21% recognized by doctors. The researchers recommend using electronic health record alerts to prompt clinicians to ask about intentional or unintentional weight loss, which can be a sign of a serious underlying condition.

SourceUniversity Hospitals Cleveland Medical Center·JournalDiagnosis·TypeData/statistical analysis·DateApr 26, 2023

University Hospitals research published in New England Journal of Medicine shows minimally invasive procedure saves most patients with severe vascular disease from amputation

The PROMISE II clinical trial showed that LimFlow therapy enabled 76% of patients to avoid amputation and experience wound healing. This minimally invasive procedure bypasses blocked arteries in the leg and rushes blood back into the foot through the veins, providing a unique alternative to major amputation.

SourceUniversity Hospitals Cleveland Medical Center·JournalNew England Journal of Medicine·DateMar 30, 2023

Researchers describe hands-on treatments for patients with low back pain after lumbar spine surgery

A recent study found that spinal manipulation is a gentle therapy used to treat low back pain in patients after previous lumbar spine surgery. The study, published in Chiropractic & Manual Therapies, compiled data from over 100 patients and reported most cases were done using a potentially gentler method.

SourceUniversity Hospitals Cleveland Medical Center·JournalChiropractic & Manual Therapies·DateMar 9, 2023

Cleveland researchers reveal how oxygen is delivered to tissues, open door to new class of drugs

Researchers at University Hospitals Cleveland Medical Center discovered that S-nitrosohemoglobin senses areas with insufficient oxygen and restores blood flow for oxygenation. This breakthrough opens up a new line of drug development to correct poor tissue oxygenation, including peripheral artery disease and sickle cell disease.

SourceUniversity Hospitals Cleveland Medical Center·JournalProceedings of the National Academy of Sciences·DateMar 1, 2023